throbber
Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 1 of 510 PageID #: 1535
`
`(cid:44)(cid:49)(cid:3)(cid:55)(cid:43)(cid:40)(cid:3)(cid:56)(cid:49)(cid:44)(cid:55)(cid:40)(cid:39)(cid:3)(cid:54)(cid:55)(cid:36)(cid:55)(cid:40)(cid:54)(cid:3)(cid:39)(cid:44)(cid:54)(cid:55)(cid:53)(cid:44)(cid:38)(cid:55)(cid:3)(cid:38)(cid:50)(cid:56)(cid:53)(cid:55)(cid:3)
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`(cid:12)(cid:3)
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`(cid:12)(cid:3)
`(cid:51)(cid:79)(cid:68)(cid:76)(cid:81)(cid:87)(cid:76)(cid:73)(cid:73)(cid:86)(cid:3)(cid:68)(cid:81)(cid:71)(cid:3)(cid:38)(cid:82)(cid:88)(cid:81)(cid:87)(cid:72)(cid:85)(cid:70)(cid:79)(cid:68)(cid:76)(cid:80)(cid:3)(cid:39)(cid:72)(cid:73)(cid:72)(cid:81)(cid:71)(cid:68)(cid:81)(cid:87)(cid:86)(cid:15)(cid:3) (cid:12)(cid:3)
`(cid:12)(cid:3)
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`(cid:12)(cid:3)
`(cid:12)(cid:3)
`(cid:12)(cid:3)
`(cid:12)(cid:3)
`(cid:12)(cid:3)
`(cid:3)
`(cid:42)(cid:40)(cid:49)(cid:40)(cid:49)(cid:55)(cid:40)(cid:38)(cid:43)(cid:15)(cid:3)(cid:44)(cid:49)(cid:38)(cid:17)(cid:3)(cid:68)(cid:81)(cid:71)(cid:3)(cid:38)(cid:44)(cid:55)(cid:60)(cid:3)(cid:50)(cid:41)(cid:3)(cid:43)(cid:50)(cid:51)(cid:40)(cid:15)(cid:3)(cid:3) (cid:12)(cid:3)
`(cid:12)(cid:3)
`(cid:12)(cid:3)
`(cid:12)(cid:3)
`(cid:12)(cid:3)
`(cid:12)(cid:3)
`(cid:12)(cid:3)
`(cid:12)(cid:3)
`(cid:12)(cid:3)
`(cid:12)(cid:3)
`(cid:45)(cid:50)(cid:44)(cid:49)(cid:55)(cid:3)(cid:38)(cid:47)(cid:36)(cid:44)(cid:48)(cid:3)(cid:38)(cid:50)(cid:49)(cid:54)(cid:55)(cid:53)(cid:56)(cid:38)(cid:55)(cid:44)(cid:50)(cid:49)(cid:3)(cid:38)(cid:43)(cid:36)(cid:53)(cid:55)(cid:3)
`(cid:36)(cid:51)(cid:51)(cid:40)(cid:49)(cid:39)(cid:44)(cid:59)(cid:3)(cid:38)(cid:3)(cid:57)(cid:50)(cid:47)(cid:56)(cid:48)(cid:40)(cid:3)(cid:20)(cid:3)
`
`(cid:89)(cid:17)(cid:3)
`(cid:3)
`
`(cid:36)(cid:48)(cid:42)(cid:40)(cid:49)(cid:3)(cid:44)(cid:49)(cid:38)(cid:17)(cid:15)(cid:3)
`
`(cid:39)(cid:72)(cid:73)(cid:72)(cid:81)(cid:71)(cid:68)(cid:81)(cid:87)(cid:3)(cid:68)(cid:81)(cid:71)(cid:3)(cid:38)(cid:82)(cid:88)(cid:81)(cid:87)(cid:72)(cid:85)(cid:70)(cid:79)(cid:68)(cid:76)(cid:80)(cid:3)(cid:51)(cid:79)(cid:68)(cid:76)(cid:81)(cid:87)(cid:76)(cid:73)(cid:73)(cid:17)(cid:3)
`
`(cid:38)(cid:17)(cid:36)(cid:17)(cid:3)(cid:49)(cid:82)(cid:17)(cid:3)(cid:20)(cid:27)(cid:16)(cid:28)(cid:21)(cid:23)(cid:16)(cid:38)(cid:41)(cid:38)(cid:3)
`
`(cid:51)(cid:79)(cid:68)(cid:76)(cid:81)(cid:87)(cid:76)(cid:73)(cid:73)(cid:86)(cid:15)(cid:3)
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`(cid:89)(cid:17)(cid:3)
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`
`(cid:39)(cid:72)(cid:73)(cid:72)(cid:81)(cid:71)(cid:68)(cid:81)(cid:87)(cid:17)(cid:3)
`
`(cid:3)(cid:3)
`
`(cid:38)(cid:17)(cid:36)(cid:17)(cid:3)(cid:49)(cid:82)(cid:17)(cid:3)(cid:20)(cid:27)(cid:16)(cid:20)(cid:22)(cid:25)(cid:22)(cid:16)(cid:38)(cid:41)(cid:38)(cid:3)
`
`

`

`Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 2 of 510 PageID #: 1536
`Appendix C to Joint Claim Construction Chart
`Index
`
`Patents-in-Suit
`Page(s)
`JA00000001 - JA00000038
`JA00000039 - JA00000077
`JA00000078 - JA00000114
`JA00000115 - JA00000132
`JA00000133 - JA00000151
`JA00000152 - JA00000246
`JA00000247 - JA00000306
`JA00000307 - JA00000361
`JA00000362 - JA00000417
`JA00000418 - JA00000443
`JA00000444 - JA00000447
`JA00000448 - JA00000465
`JA00000466 - JA00000493
`
`Description
`United States Patent No. 6,627,196
`United States Patent No. 7,371,379
`United States Application No. 14/073,659
`United States Patent No. 7,993,834
`United States Patent No. 8,076,066
`United States Patent No. 8,574,869
`United States Patent No. 6,407,213
`United States Patent No. 8,512,983
`United States Patent No. 9,714,293
`United States Patent No. 7,485,704
`United States Patent No. 7,390,660
`United States Patent No. 6,620,918
`United States Patent No. 9,249,218
`
`

`

`Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 3 of 510 PageID #: 1537
`Intrinsic Evidence for U.S. Patent No. 6,627,196
`
`JA00000733 - JA00000740
`
`3/1996
`
`U.S. Patent No. 6,627,196
`Description
`Page(s)
`U.S. Patent No. 6,627,196
`JA00000001 - JA00000038
`Prosecution History for U.S. Patent No. 6,627,196, Application No. 09/648,067
`Page(s)
`Date
`Description
`JA00000494 - JA00000661
`8/25/2000
`Original Application
`JA00000662 - JA00000669
`12/18/2001
`Office Action
`JA00000670 - JA00000671
`1/18/2002
`Response to Office Action
`JA00000672 - JA00000686
`3/28/2002
`Non-Final Rejection
`JA00000687 - JA00000697
`8/28/2002
`Amendment and Response to Office Action
`JA00000698 - JA00000702
`12/3/2002
`Final Rejection
`JA00000703 - JA00000707
`3/3/2003
`Response to Office Action
`JA00000708 - JA00000709
`4/28/2003
`Examiner Interview Summary Record
`JA00000710 - JA00000712
`5/27/2003
`Applicant Interview Summary Record
`JA00000720 - JA00000724
`5/29/2003
`Amendment and Response to Office Action
` JA00000713 - JA00000719
`6/2/2003
`Examiner Interview Summary Record
`JA00000725 - JA00000732
`6/6/2003
`Notice of Allowance
`Baselga et al., Phase II Study of Weekly Intravenous Recombinant Humanized Anti-
`p185HER2 Monoclonal Antibody in Patients With HER2/neu-Overexpressing
`Metastatic Breast Cancer, J. CLIN. ONCOL. 14(3):737-744
`Pegram et al., Phase II Study of Receptor-Enhanced Chemosensitivity Using
`Recombinant Humanized Anti-pl85HER2 /neu Monoclonal Antibody Plus Cisplatin in
`Patients With HER2/neu-Overexpressing Metastatic Breast Cancer Refractory to
`Chemotherapy Treatment, J. CLIN. ONCOL. 16(8):2659-2671
`
`JA00000741 - JA00000753
`
`1998
`
`Related Applications
`5/31/2006
`JA00000754 - JA00000841
`1/9/2008
`JA00000842 - JA00000852
`7/2/2008
`JA00000853 - JA00000861
`10/29/2008
`JA00000862 - JA00000871
`1/29/2009
`JA00000872 - JA00000881
`5/14/2009
`JA00000882 - JA00000888
`8/14/2009
`JA00000889 - JA00000896
`9/11/2009
`JA00000897 - JA00000902
`9/11/2009
`JA00000903 - JA00000903
`5/7/2010
`JA00000904 - JA00000904
`12/23/2010
`JA00000905 - JA00000913
`7/11/2011
`JA00000914 - JA00000915
`6/23/2011
`JA00000916 - JA00000994
`4/17/2012
`JA00000995 - JA00000996
`3/8/2012
`JA00000997 - JA00001073
`2/19/2013
`JA00001074 - JA00001076
`7/18/2013
`JA00001077 - JA00001089
`2/20/2014
`JA00001090 - JA00001091
`See Appendix C Volume 3 for the following
`JA00001092 - JA00001185
`6/20/2003
`JA00001186 - JA00001195
`5/11/2006
`JA00001196 - JA00001205
`5/24/2006
`JA00001206 - JA00001217
`8/9/2006
`JA00001218 - JA00001225
`2/9/2007
`JA00001226 - JA00001235
`5/4/2007
`JA00001236 - JA00001243
`10/4/2007
`JA00001244 - JA00001248
`12/28/2007
`JA00001249 - JA00001250
`1/4/2008
`See Appendix C Volume 4 for the following
`JA00001251 - JA00001338
`11/6/2013
`JA00001339 - JA00001347
`8/6/2015
`JA00001348 - JA00001350
`11/19/2015
`JA00001351 - JA00001357
`1/6/2016
`JA00001358 - JA00001359
`1/6/2016
`
`Application No. 11/443,943, Divisional Application
`Office Action
`Amendment and Response to Office Action
`Office Action
`Amendment and Response to Office Action
`Office Action
`Amendment and Response to Office Action
`Office Action
`Advisory Action
`Request for Continued Examination
`Office Action
`Abandonment
`Application No. 13/167,599 Divisional Application
`Abandonment
`Application No. 13/415,271 File History, Divisional Application
`Preliminary Amendment
`Office Action
`Abandonment
`
`’379 Patent File History, Application No. 10/600,152, Divisional Application
`Office Action
`Amendment and Response to Office Action
`Non-Final Rejection
`Response to Office Action
`Final Rejection
`Amendment and Response to Office Action
`Notice of Allowance
`Examiner Interview Summary Record
`
`Application No. 14/073,659, Continuation Application
`Office Action
`Applicant Initiated Interview Summary
`Amendment and Response to Office Action
`Terminal Disclaimer
`
`

`

`Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 4 of 510 PageID #: 1538
`Intrinsic Evidence for U.S. Patent No. 6,627,196
`
`Prosecution History for U.S. Patent No. 6,627,196, Application No. 09/648,067
`Page(s)
`Date
`Description
`JA00001360 - JA00001373
`11/18/2016
`Office Action
`JA00001374 - JA00001376
`5/3/2017
`Examiner and Applicant Initiated Summaries
`JA00001377 - JA00001398
`5/17/2017
`Amendment and Response to Office Action
`JA00001399 - JA00001416
`7/6/2018
`Office Action
`JA00001417 - JA00001419
`9/13/2018
`Applicant Initiated Interview Summary
`JA00001420 - JA00001445
`10/5/2018
`Amendment and Response to Office Action
`JA00001446 - JA00001453
`10/23/2018
`Notice of Allowance
`
`

`

`Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 5 of 510 PageID #: 1539
`Intrinsic Evidence for U.S. Patent No. 7,371,379
`
`JA00000733 - JA00000740
`
`3/1996
`
`U.S. Patent No. 7,371,379
`Description
`Page(s)
`U.S. Patent No. 7,371,379
`JA00000039 - JA00000077
`Prosecution History for U.S. Patent No. 7,371,379, Application No. 10/600,152
`Page(s)
`Date
`Description
`JA00001092 - JA00001185
`6/20/2003
`’379 Patent File History, Application No. 10/600,152, Divisional Application
`JA00001186 - JA00001195
`5/11/2006
`Office Action
`JA00001196 - JA00001205
`5/24/2006
`Amendment and Response to Office Action
`JA00001206 - JA00001217
`8/9/2006
`Non-Final Rejection
`JA00001218 - JA00001225
`2/9/2007
`Response to Office Action
`JA00001226 - JA00001235
`5/4/2007
`Final Rejection
`JA00001236 - JA00001243
`10/4/2007
`Amendment and Response to Office Action
`JA00001244 - JA00001248
`12/28/2007 Notice of Allowance
`JA00001249 - JA00001250
`1/4/2008
`Examiner Interview Summary Record
`See Appendix C Volume 2 for the following
`Prosecution History for U.S. Patent No. 6,627,196, Application No. 09/648,067 Original
`JA00000494 - JA00000661
`8/25/2000
`Application
`JA00000662 - JA00000669
`12/18/2001 Office Action
`JA00000670 - JA00000671
`1/18/2002
`Response to Office Action
`JA00000672 - JA00000686
`3/28/2002
`Non-Final Rejection
`JA00000687 - JA00000697
`8/28/2002
`Amendment and Response to Office Action
`JA00000698 - JA00000702
`12/3/2002
`Final Rejection
`JA00000703 - JA00000707
`3/3/2003
`Response to Office Action
`JA00000708 - JA00000709
`4/28/2003
`Examiner Interview Summary Record
`JA00000710 - JA00000712
`5/27/2003
`Applicant Interview Summary Record
`JA00000720 - JA00000724
`5/29/2003
`Amendment and Response to Office Action
` JA00000713 - JA00000719
`6/2/2003
`Examiner Interview Summary Record
`JA00000725 - JA00000732
`6/6/2003
`Notice of Allowance
`Baselga et al., Phase II Study of Weekly Intravenous Recombinant Humanized Anti-p185HER2
`Monoclonal Antibody in Patients With HER2/neu-Overexpressing Metastatic Breast Cancer, J.
`CLIN. ONCOL. 14(3):737-744
`Pegram et al., Phase II Study of Receptor-Enhanced Chemosensitivity Using Recombinant
`Humanized Anti-pl85HER2 /neu Monoclonal Antibody Plus Cisplatin in Patients With
`HER2/neu-Overexpressing Metastatic Breast Cancer Refractory to Chemotherapy Treatment, J.
`CLIN. ONCOL. 16(8):2659-2671
`
`JA00000741 - JA00000753
`
`1998
`
`See Appendix C Volume 4 for the following
`Application No. 14/073,659, Continuation Application
`JA00001251 - JA00001338
`11/6/2013
`Office Action
`JA00001339 - JA00001347
`8/6/2015
`JA00001348 - JA00001350
`11/19/2015 Applicant Initiated Interview Summary
`JA00001351 - JA00001357
`1/6/2016
`Amendment and Response to Office Action
`JA00001358 - JA00001359
`1/6/2016
`Terminal Disclaimer
`JA00001360 - JA00001373
`11/18/2016 Office Action
`JA00001374 - JA00001376
`5/3/2017
`Examiner and Applicant Initiated Summaries
`JA00001377 - JA00001398
`5/17/2017
`Amendment and Response to Office Action
`JA00001399 - JA00001416
`7/6/2018
`Office Action
`JA00001417 - JA00001419
`9/13/2018
`Applicant Initiated Interview Summary
`JA00001420 - JA00001445
`10/5/2018
`Amendment and Response to Office Action
`JA00001446 - JA00001453
`10/23/2018 Notice of Allowance
`
`

`

`Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 6 of 510 PageID #: 1540
`Intrinsic Evidence for U.S. Patent Application No. 14/073,659
`
`U.S. Patent Application No. 14/073,659
`Page(s)
`Description
`JA00000078 - JA00000114
`U.S. Patent Application No. 14/073,659
`Prosecution History for U.S. Patent Application No. 14/073,659
`Page(s)
`Date
`Description
`JA00001251 - JA00001338
`11/6/2013
`Application No. 14/073,659, Continuation Application
`JA00001339 - JA00001347
`8/6/2015
`Office Action
`JA00001348 - JA00001350
`11/19/2015
`Applicant Initiated Interview Summary
`JA00001351 - JA00001357
`1/6/2016
`Amendment and Response to Office Action
`JA00001358 - JA00001359
`1/6/2016
`Terminal Disclaimer
`JA00001360 - JA00001373
`11/18/2016
`Office Action
`JA00001374 - JA00001376
`5/3/2017
`Examiner and Applicant Initiated Summaries
`JA00001377 - JA00001398
`5/17/2017
`Amendment and Response to Office Action
`JA00001399 - JA00001416
`7/6/2018
`Office Action
`JA00001417 - JA00001419
`9/13/2018
`Applicant Initiated Interview Summary
`JA00001420 - JA00001445
`10/5/2018
`Amendment and Response to Office Action
`JA00001446 - JA00001453
`10/23/2018
`Notice of Allowance
`See Appendix C Volume 2 for the following
`JA00000494 - JA00000661
`8/25/2000
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`12/18/2001
`JA00000670 - JA00000671
`1/18/2002
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`
`Prosecution History for U.S. Patent No. 6,627,196,
`Application No. 09/648,067 Original Application
`Office Action
`Response to Office Action
`Non-Final Rejection
`Amendment and Response to Office Action
`Final Rejection
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`Examiner Interview Summary Record
`Applicant Interview Summary Record
`Amendment and Response to Office Action
`Examiner Interview Summary Record
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`
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`
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`
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`6/20/2003
`JA00001186 - JA00001195
`5/11/2006
`JA00001196 - JA00001205
`5/24/2006
`JA00001206 - JA00001217
`8/9/2006
`
`

`

`Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 7 of 510 PageID #: 1541
`Intrinsic Evidence for U.S. Patent Application No. 14/073,659
`
`See Appendix C Volume 3 for the following
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`2/9/2007
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`5/4/2007
`JA00001236 - JA00001243
`10/4/2007
`JA00001244 - JA00001248
`12/28/2007
`JA00001249 - JA00001250
`1/4/2008
`
`Response to Office Action
`Final Rejection
`Amendment and Response to Office Action
`Notice of Allowance
`Examiner Interview Summary Record
`
`

`

`Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 8 of 510 PageID #: 1542
`Intrinsic Evidence for U.S. Patent No. 7,993,834
`
`U.S. Patent No. 7,993,834
`Description
`Page(s)
`U.S. Patent No. 7,993,834
`JA00000115 - JA00000132
`Prosecution History for U.S. Patent No. 7,993,834, Application No. 11/942,449
`Page(s)
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`JA00001454 - JA00001504
`11/19/2007
`Continuation Application
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`6/11/2009
`Office Action
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`9/11/2009
`Amendment and Response to Office Action
`JA00001539 - JA00001551
`1/7/2010
`Office Action
`JA00001552 - JA00001560
`4/7/2010
`Amendment and Response to Office Action
`JA00001561 - JA00001570
`6/23/2010
`Office Action
`JA00001571 - JA00001576
`10/25/2010 Response to Office Action
`JA00001577 - JA00001579
`11/24/2010 Advisory Action
`JA00001580 - JA00001584
`11/29/2010
`Supplemental Amendment and Response to Office Action
`JA00001585 - JA00001586
`4/1/2011
`Notice of Allowance
`Application No. 09/863,101 File History, Application No.
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`5/18/2001
`09/863,101, Original Application
`JA00001685 - JA00001688
`9/25/2002
`Office Action
`JA00001689 - JA00001692
`10/22/2002 Response to Office Action
`JA00001693 - JA00001699
`12/31/2002 Office Action
`JA00001700 - JA00001705
`5/29/2003
`Amendment and Response to Office Action
`JA00001706 - JA00001713
`8/25/2003
`Office Action
`JA00001714 - JA00001717
`1/29/2004
`Notice of Appeal
`JA00001718 - JA00001725
`6/24/2004
`Amendment and Response to Office Action and RCE
`JA00001726 - JA00001731
`9/16/2004
`Office Action
`JA00001732 - JA00001733
`10/19/2004
`Examiner Interview Summary Record
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`11/9/2004
`Amendment and Response to Office Action
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`3/14/2005
`Office Action
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`7/13/2005
`Amendment and Response to Office Action
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`9/27/2005
`Office Action
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`3/27/2006
`Amendment and Response to Office Action
`JA00001778 - JA00001778
`6/20/2006
`Office Action
`JA00001795 - JA00001796
`6/27/2007
`Abandonment
`Application No. 11/441,995 File History. Application
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`No. 11/441,995, Divisional Application
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`9/22/2006
`Office Action
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`10/23/2006 Response to Office Action
`JA00001871 - JA00001876
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`Office Action
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`2/16/2007
`Response to Office Action
`JA00001880 - JA00001899
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`12/28/2007 Abandonment
`’402 Patent File History. Application No. 13/323,322,
`JA00001902 - JA00001957
`12/12/2011
`Continuation Application
`
`

`

`Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 9 of 510 PageID #: 1543
`Intrinsic Evidence for U.S. Patent No. 7,993,834
`
`Prosecution History for U.S. Patent No. 7,993,834, Application No. 11/942,449
`Page(s)
`Date
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`JA00001958 - JA00001964
`5/4/2012
`Office Action
`JA00001965 - JA00001967
`11/2/2012
`Response to Office Action
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`11/2/2012
`Terminal Disclaimers
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`1/16/2013
`Notice of Allowance
`See Appendix C Volume 6 for the following
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`JA00001975 - JA00002124
`3/23/2007
`Continuation Application
`Original Application Claims
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`3/23/2007
`Office Action
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`5/1/2008
`Amendment and Response to Office Action
`JA00002145 - JA00002151
`11/3/2008
`Office Action
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`1/21/2009
`Amendment and Response to Office Action
`JA00002166 - JA00002175
`4/16/2009
`Advisory Action
`JA00002176 - JA00002178
`5/13/2009
`Request for Continued Examination
`JA00002179 - JA00002179
`2/1/2010
`Notice of Allowance
`JA00002180 - JA00002186
`7/22/2010
`Request for Continued Examination
`JA00002187 - JA00002187
`9/23/2010
`Office Action
`JA00002188 - JA00002193
`4/27/2011
`Amendment and Response to Office Action
`JA00002194 - JA00002197
`5/19/2011
`Notice of Allowance
`JA00002198 - JA00002202
`8/5/2011
`JA00002203 - JA00002204
`11/17/2011 Notice of Allowance
`
`

`

`Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 10 of 510 PageID #: 1544
`Intrinsic Evidence for U.S. Patent No. 8,076,066
`
`U.S. Patent No. 8,076,066
`Description
`Page(s)
`U.S. Patent No. 8,076,066
`JA00000133 - JA00000151
`Prosecution History for U.S. Patent No. 8,076,066, Application No. 11/690,304
`Page(s)
`Date
`Description
`’066 Patent File History. Application No. 11/690,304,
`JA00001975 - JA00002124
`3/23/2007
`Continuation Application
`JA00002125 - JA00002135
`3/23/2007
`Original Application Claims
`JA00002136 - JA00002144
`5/1/2008
`Office Action
`JA00002145 - JA00002151
`11/3/2008
`Amendment and Response to Office Action
`JA00002152 - JA00002165
`1/21/2009
`Office Action
`JA00002166 - JA00002175
`4/16/2009
`Amendment and Response to Office Action
`JA00002176 - JA00002178
`5/13/2009
`Advisory Action
`JA00002179 - JA00002179
`2/1/2010
`Request for Continued Examination
`JA00002180 - JA00002186
`7/22/2010
`Notice of Allowance
`JA00002187 - JA00002187
`9/23/2010
`Request for Continued Examination
`JA00002188 - JA00002193
`4/27/2011
`Office Action
`JA00002194 - JA00002197
`5/19/2011
`Amendment and Response to Office Action
`JA00002198 - JA00002202
`8/5/2011
`Notice of Allowance
`JA00002203 - JA00002204
`11/17/2011 Notice of Allowance
`See Appendix C Volume 5 for the following
`’834 Patent File History Application No. 11/942,449,
`JA00001454 - JA00001504
`11/19/2007
`Continuation Application
`Office Action
`JA00001505 - JA00001523
`6/11/2009
`Amendment and Response to Office Action
`JA00001524 - JA00001538
`9/11/2009
`Office Action
`JA00001539 - JA00001551
`1/7/2010
`Amendment and Response to Office Action
`JA00001552 - JA00001560
`4/7/2010
`Office Action
`JA00001561 - JA00001570
`6/23/2010
`JA00001571 - JA00001576
`10/25/2010 Response to Office Action
`JA00001577 - JA00001579
`11/24/2010 Advisory Action
`Supplemental Amendment and Response to Office
`JA00001580 - JA00001584
`11/29/2010
`Action
`JA00001585 - JA00001586
`4/1/2011
`Notice of Allowance
`Application No. 09/863,101 File History, Application
` JA00001590 - JA00001684
`5/18/2001
`No. 09/863,101, Original Application
`JA00001685 - JA00001688
`9/25/2002
`Office Action
`JA00001689 - JA00001692
`10/22/2002 Response to Office Action
`JA00001693 - JA00001699
`12/31/2002 Office Action
`JA00001700 - JA00001705
`5/29/2003
`Amendment and Response to Office Action
`JA00001706 - JA00001713
`8/25/2003
`Office Action
`JA00001714 - JA00001717
`1/29/2004
`Notice of Appeal
`JA00001718 - JA00001725
`6/24/2004
`Amendment and Response to Office Action and RCE
`JA00001726 - JA00001731
`9/16/2004
`Office Action
`JA00001732 - JA00001733
`10/19/2004
`Examiner Interview Summary Record
`
`

`

`Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 11 of 510 PageID #: 1545
`Intrinsic Evidence for U.S. Patent No. 8,076,066
`
`Prosecution History for U.S. Patent No. 8,076,066, Application No. 11/690,304
`Page(s)
`Date
`Description
`JA00001734 - JA00001737
`11/9/2004
`Amendment and Response to Office Action
`JA00001738 - JA00001744
`3/14/2005
`Office Action
`JA00001745 - JA00001752
`7/13/2005
`Amendment and Response to Office Action
`JA00001753 - JA00001767
`9/27/2005
`Office Action
`JA00001768 - JA00001777
`3/27/2006
`Amendment and Response to Office Action
`JA00001778 - JA00001778
`6/20/2006
`Office Action
`JA00001795 - JA00001796
`6/27/2007
`Abandonment
`JA00001797 - JA00001861
`5/26/2006
`Application No. 11/441,995 Divisional Application
`JA00001862 - JA00001866
`9/22/2006
`Office Action
`JA00001867 - JA00001870
`10/23/2006 Response to Office Action
`JA00001871 - JA00001876
`1/16/2007
`Office Action
` JA00001877 - JA00001879
`2/16/2007
`Response to Office Action
`JA00001880 - JA00001899
`5/17/2007
`Office Action
`JA00001900 - JA00001901
`12/28/2007 Abandonment
`’402 Patent File History. Application No.
`JA00001902 - JA00001957
`12/12/2011
`13/323,322, Continuation Application
`JA00001958 - JA00001964
`5/4/2012
`Office Action
`JA00001965 - JA00001967
`11/2/2012
`Response to Office Action
`JA00001968 - JA00001969
`11/2/2012
`Terminal Disclaimers
`JA00001970 - JA00001974
`1/16/2013
`Notice of Allowance
`
`

`

`Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 12 of 510 PageID #: 1546
`Intrinsic Evidence for U.S. Patent No. 8,574,869
`
`JA00002458 - JA00002467
`
`2010
`
`JA00002468 - JA00002478
`
`2010
`
`U.S. Patent No. 8,574,869
`Description
`Page(s)
`U.S. Patent No. 8,574,869
`JA00000152 - JA00000246
`Prosecution History for U.S. Patent No. 8,574,869, Application No. 13/354,223
`Page(s)
`Date
`Description
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`JA00002205 - JA00002394
`1/19/2012
`13/354,223, Continuation Application
`JA00002395 - JA00002407
`9/26/2012
`Preliminary Amendment and Remarks
`JA00002408 - JA00002413
`1/10/2013
`Office Action
`JA00002414 - JA00002416
`2/8/2013
`Amendment and Response to Office Action
`JA00002417 - JA00002426
`2/25/2013
`Non-Final Rejection
`JA00002427 - JA00002442
`5/24/2013
`Amendment Response
`JA00002443 - JA00002448
`7/3/2013
`Examiner initiated interview summary
`JA00002449 - JA00002452
`7/3/2013
`Notice of Allowance
`JA00002453 - JA00002457
`7/26/2013
`Amendment after Allowance
`Melody Trexler-Schmidt et al., Identification and
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`Yung-Hsian Kao et al., Mechanism of Antibody
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`Office Action
`7/19/2011
`Abandonment
`2/16/2012
`Application No. 14/043,758 File History, Divisional
`10/1/2013
`Application
`Preliminary Amendment
`1/17/2014
`Office Action
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`11/17/2015 Response to Office Action
`2/9/2016
`Office Action
`8/8/2016
`Amendment and Response to Office Action
`10/18/2016 Office Action
`1/17/2017
`Applicant Initiated Interview Summary
`2/15/2017
`Response to Office Action
`3/3/2017
`Examiner initiated Interview Summary
`5/26/2017
`Abandonment
`4/17/2017
`Application No. 15/488,917 Divisional Application
`7/25/2017
`Preliminary Amendment
`
`JA00002510 - JA00002690
`JA00002691 - JA00002703
`JA00002704 - JA00002705
`JA00002706 - JA00002859
`JA00002860 - JA00002871
`JA00002872 - JA00002880
`JA00002881 - JA00002885
`JA00002886 - JA00002899
`JA00002900 - JA00002917
`JA00002918 - JA00002934
`JA00002935 - JA00002937
`JA00002938 - JA00002948
`JA00002949 - JA00002949
`JA00002950 - JA00002951
`JA00002952 - JA00003110
`JA00003111 - JA00003123
`
`JA00002479 - JA00002509
`
`2/12/2004
`
`

`

`Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 13 of 510 PageID #: 1547
`Intrinsic Evidence for U.S. Patent No. 8,512,983
`
`1990
`
`U.S. Patent No. 8,512,983
`Description
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`U.S. Patent No. 8,512,983
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`6/4/2012
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`
`1971
`
`

`

`Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 14 of 510 PageID #: 1548
`Intrinsic Evidence for U.S. Patent No. 9,714,293
`
`U.S. Patent No. 9,714,293
`Description
`Page(s)
`U.S. Patent No. 9,714,293
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`10/9/2015
`Preliminary amendment to claims
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`11/29/2016 Applicant Arguments/Remarks Made in Amendment
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`
`

`

`Case 1:18-cv-01363-CFC Document 48-1 Filed 12/11/18 Page 15 of 510 PageID #: 1549
`Intrinsic Evidence for U.S. Patent No. 7,485,704
`
`U.S. Patent No. 7,485,704
`Description
`Page(s)
`U.S. Patent No. 7,485,704
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`JA00003483-JA00003533
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`Original Application
`JA00003534-JA00003540
`10/6/2006
`Office Action
`JA00003541-JA00003549
`1/4/2007
`Amendment and Response to Office Action
`JA00003550-JA00003559
`3/20/2007
`Office Action
`JA00003560-JA00003569
`6/14/2007
`Amendment and Response to Office Action
`JA00003570-JA00003572
`7/10/2007
`Advisory Action
`JA00003573-JA00003573
`9/20/2007
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`JA00003574-JA00003580
`12/26/2007 Office Action
`JA00003581-JA00003591
`4/25/2008
`Amendment and Response to Office Action
`JA00003592-JA00003597
`7/14/2008
`Office Action
`JA00003598-JA00003603
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`JA00003604-JA00003609
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`JA00003610-JA00003619
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`3/2/2010
`Amendment and Response to Office Action
`JA00003705-JA00003706
`5/3/2010
`Terminal Disclaimer
`JA00003707-JA00003713
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`JA00003714-JA00003781
`9/16/2016
`IPR2016-01837 Paper 1
`JA00003782-JA00003803
`4/7/2017
`IPR2016-01837 Paper 19, Decision on Institution
`IPR2016-01837 Exhibit 2010, Deposition Transcript of
`JA00003804-JA00004016
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`Todd M. Przybycien
`JA00004017-JA00004080
`6/28/2017
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`IPR2016-01837 Exhibit 2008, Declaration of Steven
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`Cramer, Ph.D.
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`JA00004265-JA00004316
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`IPR2016-01837 Paper 40, Final Written Decision
`Appeal From The United States Patent And Trademark
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`1933 (Aug. 17, 2018)
`
`JA000043

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