`University of California San Francisco
`
`CURRICULUM VITAE
`
`ROBERT LUKE NUSSBAUM
`
`Professor In Residence Step 7
`Department of Medicine
`School of Medicine, 2006-
`Holly Smith Distinguished Professor of Science and Medicine
`Chief, Division of Medical Genetics
`
`Professor of Neurology, UCSF (Secondary)
`
`Member, UCSF Institute for Human Genetics
`Member. Biomedical Sciences Graduate Group
`
`HSE901E, Box 0794
`University of California, San Francisco
`
`(415) 476-3200
`Voice
`(415) 502-0720
`Fax:
`E-mail: nussbaumr@humgen.ucsf.edu
`http://medicine.ucsf.edu/genetics/
`http://bms.ucsf.edu/directory/faculty/robert-nussbaum-md
`
`
`Name:
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`Position:
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`Address:
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`1976-1977
`
`1977-1978
`
`
`EDUCATION
`
`1967-1971 Harvard College, Cambridge, MA A.B. Appl Mathematics, cum laude
`1971-1975 Harvard Medical School
`M.D. Medicine
`1971-1975 Harvard-MIT Program in Health Sciences and Technology M.D. Medicine
`1975-1976
`Intern in Internal Medicine, Barnes Hospital, Washington University, St.
`Louis, Mo.
`Junior Assistant Resident, Barnes Hospital, Washington University, St.
`Louis, Mo.
`Senior Assistant Resident, Barnes Hospital, Washington University, St.
`Louis, Mo. (Chief Resident, John Cochran VA Hospital, Wash University
`service)
`Fellow in Medical Genetics, Baylor College of Medicine, Houston, TX
`1978-1981
`1981-1983 Associate, Howard Hughes Medical Institute, Baylor College of Medicine.
`
`LICENSES, CERTIFICATIONS
`
`4/26/06
`12/31/94
`
`California Medical License C52306, exp. 2/28/2014 (active)
`Maryland Medical License D46971, exp. 9/30/07 (Inactive)
`
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`1
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`Ariosa Exhibit 1038, pg. 1
`IPR2013-00277
`
`

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`12/3/76
`2/21/81
`10/8/84
`
`9/13/78
`3/19/82
`9/24/93
`
`Missouri Medical License (Inactive)
`Texas Medical License (Inactive)
`Pennsylvania Medical License (Inactive)
`
`Certified, American Board of Internal Medicine #65308, 9/13/78
`Certified, American Board of Medical Genetics in Clinical Genetics #1367
`Certified American Board of Medical Genetics, Clinical Molecular Genetics
`#93220; Recertified, 8/15/2002
`Basic Federal Project Officer Certification, DHHS
`
`7/28/94
`
`PRINCIPLE POSITIONS HELD
`
`1981-1984 Assistant Professor of Medicine, Baylor College of Medicine
`1983-1984 Associate Investigator, Howard Hughes Medical Institute at Baylor
`1984-1993 Associate Investigator, Howard Hughes Medical Institute at UPenn
`1984-1989 Assistant Professor of Human Genetics, University of
`
`
`Pennsylvania, School of Medicine (Primary)
`1989-1993 Associate Professor of Human Genetics
`
`
`University of Pennsylvania School of Medicine
`1993-1994
`Professor of Genetics, University
`
`
`of Pennsylvania School of Medicine
`1993-2006
`Chief, Genetic Disease Research Branch, NHGRI
`1995-2006 Acting Chief, Inherited Disease Research Branch, NHGRI
`2000-2006 Medical Director, Johns Hopkins/NIH joint training program in Genetic
`Counseling.
`Professor of Medicine and Chief, Division of Medical Genetics,
`Department of Medicine, UCSF
`Faculty member, Biomedical Sciences Graduate Group, UCSF
`Professor of Neurology (Secondary), UCSF
`
`2006-now
`
`
`2006-now
`2007-now
`
`OTHER POSITIONS HELD CONCURRENTLY:
`
`2006-
`2007-2010
`2006-2010
`2008-
`
`Member, Executive Committee, UCSF Institute for Human Genetics
`Executive Committee, Medical Scientist Training Program, UCSF
`Executive Committee, Biomedical Sciences Graduate Group, UCSF
`Director, Molecular Medicine Pathway to Discovery, UCSF School of
`Medicine
`
`
`HONORS AND AWARDS
`1975
`
`Alpha Omega Alpha, Harvard Medical School
`1977
`
`Outstanding Medical Resident, Barnes Hospital
`1978-80
`Arthritis Foundation Research Fellowship
`1986
`
`Medical Research Award, Lowe's Syndrome Association
`1987
`
`Elected Member, American Society for Clinical Investigation
`1989
`
`Dean’s Award for Excellence in Basic Science Teaching, University of
`Pennsylvania
`
`
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`2
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`Ariosa Exhibit 1038, pg. 2
`IPR2013-00277
`
`

`

`
`
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`
`
`1989
`1989
`
`1989
`1990
`1990
`
`1991
`
`
`1991
`
`
`1993
`1994
`
`1996
`1996
`
`1996
`
`1996
`
`1998
`
`1999
`
`2000
`
`2003
`
`2003
`
`2004
`
`
`
`
`2004
`2007
`
`2008
`
`2009
`2010
`2011
`
`Master of Arts (honorary), University of Pennsylvania
`Commendation for Outstanding Teaching, University of Pennsylvania
`School of Medicine, Class of 1992
`Member, Human Genome Organization
`Leonard Berwick Memorial Teaching Award, University of Pennsylvania
`Commendation for Outstanding Teaching, University of Pennsylvania
`School of Medicine, Class of 1993
`Commendation for Outstanding Teaching, University of Pennsylvania
`School of Medicine, Class of 1994
`Sir Clavering Fison Visiting Professor, Institute for Child
`Health, Hospital for Sick Children, Great Ormond Street, London, UK
`Medical Research Award, Lowe's Syndrome Association
`Morehouse School of Medicine Human Genome/Molecular Medicine
`Symposium Lecturer
`Medical Research Award, Lowe's Syndrome Association
`Elected Member, Association of American Physicians
`NHGRI Director's Award
`NIH Director's Award
`NHGRI Director's Award (Group award)
`G. Burroughs Mider Lectureship, National Institutes of Health
`Special Service Award, NIMH
`NHGRI Director’s Award (Group Award)
`Forbes Lectureship, Medical College of Virginia
`Elected Member, Institute of Medicine of the National Academies of
`Science.
`NHGRI Director’s Distinguished Service Award
`Certificate of Appreciation from the NHGRI for Teaching and Mentoring in
`the NIH/Johns Hopkins Genetic Counseling Training Program
`Legacy Award, Lowe’s Syndrome Association, awarded in recognition of
`over two decades of service and commitment to patients and families with
`Lowe Syndrome.
`Excellence In Teaching Award, UCSF Academy of Medical Educators
`Elected Fellow, American College of Physicians
`Klaus Joachim Zülch-Prize for Neurological Research, Gertrud Reemtsma
`Foundation/Max Planck Society
`
`
`
`KEYWORDS/AREAS OF INTEREST:
`
`Parkinson disease, animal models of neurological disease, alpha-synuclein, Lowe
`syndrome, phosphatidylinositol metabolism, personalized medicine, human genetics,
`genomics, physician-scientist education, medical school education.
`
`PROFESSIONAL ACTIVITIES
`
`CLINICAL
`
`
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`3
`
`Ariosa Exhibit 1038, pg. 3
`IPR2013-00277
`
`

`

`2006-now
`2007-now
`
`2008-now
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`2006-2007
`2007-now
`2006-2009
`
`Consultant in Genetics, UCSF Medical Center
`Director, Program in Cardiovascular Genetics. I have attended in this
`clinic one afternoon per week for the past 3 years as well as supervising a
`genetic counselor.
`Director, Cancer Risk Program, Diller Cancer Center and UCSF/Mt. Zion
`Medical Center. I have attended I this clinic three afternoons per month as
`well as supervising the clinical activities of 5 genetic counselors.
`I attended in General Genetics Clinic (Pediatrics) one morning per week.
`I attended in General Genetics Clinic (Pediatrics) one morning per month.
`I attended in Metabolic Clinic two afternoons per month.
`
`SUMMARY OF CLINICAL ACTIVITIES
`
`American Society of Human Genetics
`Society for Inherited Metabolic Disease
`Human Genome Organization
`American College of Medical Genetics
`American Society of Cell Biology
`Society for Neuroscience
`
`I pioneered the introduction of genetic counseling and family outreach into adult
`cardiology, established a new genetics focus in the care of patients with cardiovascular
`disease through a partnership with the Division of Cardiology and the Heart and Vascular
`Center of the UCSF Medical Center. I expanded the genetics care of patients with
`hereditary cancers to include multiple neoplasia syndromes and formed partnerships with
`the urological surgery, neurological surgery, and head and neck surgery programs.
`
`PROFESSIONAL ORGANIZATIONS
`
`Memberships
`
`1980-
`1986-
`1989-
`1991-
`2003-
`2006-
`
`Service to Professional Societies and Organizations
`
`Co-Chair, Xq committee, International Human Gene Mapping
`1988-1991
`Conferences HGM 9.5, (1988), 10 (1989), 10.5 (1990) and 11 (1991)
`
`
`1990-1992 American Society of Human Genetics Annual Meeting Program
`Committee (Chairman of Program Committee, 1992 meeting)
`1992-1996 American Society of Human Genetics Board of Directors
`1998-2000 American Society of Human Genetics Awards Committee
`1995, 1997 Gordon Conference on Molecular Genetics (Co-Chair 1995, Chair 1997)
`1999-2002 Molecular Genetic Pathology Test Committee, American College of
`Pathology
`1997-2000 American College of Medical Genetics, Board of Directors
`
`
`(Chairman of Program Committee, 1999 meeting)
`2000-2006
`Board of Scientific Overseers, The Jackson Laboratory
`2004
`
`President, American Society of Human Genetics
`2005-2008 American Society of Human Genetics Awards Committee
`
`
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`4
`
`Ariosa Exhibit 1038, pg. 4
`IPR2013-00277
`
`

`

`2006
`
`2006-2008
`2007
`
`1992-
`1995-
`2006
`2006-
`2007-
`
`2009-
`2009-2011
`
`ACCE Guidelines Committee on Warfarin Dosing, American College of
`Medical Genetics
`2006-2008 Association of Professors of Human and Medical Genetics representative
`for UCSF
`Scientific Review Committee, the Parkinson’s Study Group
`Personalized Health Care Expert Panel, Dept. of Health and Human
`Services
`March of Dimes/Birth Defects Foundation Clinical Advisory Committee
`Medical Advisory Board, The Lowe Syndrome Association
`External Advisory Committee, The Parkinson’s Institute
`dbGaP Working Group, NCBI, NLM
`Member, Institute of Medicine Roundtable on Translating Genomic Based
`Research for Health.
`OMIM Scientific Advisory Board
`Scientific Advisory Board, Institute of Genetics, Canadian Institutes for
`Health Research.
`March of Dimes/Basil O’Connor Grant Review Committee
`Board of Directors, American Board of Medical Genetics
`NCBI/NIH Working Group on Medical Genetics
`
`2010-
`2010-
`2010-
`
` SERVICE TO PROFESSIONAL PUBLICATIONS:
`
`Editorial Board, American Journal of Human Genetics
`1987-89
`Editorial Board, Cytogenetics and Cell Genetics
`1989-1993
`Communicating Editor, Human Mutation
`1992-1998
`1994-1996 Editorial Board, Human Genetics
`1997-
`Editorial Board, Journal of Clinical Investigation
`1997-2003
`Editor-in-Chief, Human Genetics (for Asia and Americas)
`1998-
`Editorial Board, Human Molecular Genetics, American Journal of Medical
`Genetics, Functional and Integrative Genomics, Journal of Clinical
`Investigation, Genome Medicine.
`Section Editor, Genetics in Medicine
`2006-
`Ad hoc Reviewer for Nature, Nature Genetics, Nature Neuroscience, Neurology, Journal of
`Neuroscience, Neurogenetics, American Journal of Human Genetics, Molecular and
`Cellular Biology, Journal of Cell Biology, Human Mutation, Human Genetics, New
`England Journal of Medicine.
`
`
`INVITED PRESENTATIONS (Since 2004)
`
`INTERNATIONAL
`
`Lowe Syndrome Trust International Meeting on Lowe Syndrome, December 2004
`(platform)
`Parkinson Disease and Diffuse Lewy Body Disease Symposium, World Parkinson’s
`Congress, Washington DC February 22, 2006 (platform)
`World Parkinson’s Disease Congress, Washington, DC, February 23, 2006 (platform)
`
`
`
`5
`
`Ariosa Exhibit 1038, pg. 5
`IPR2013-00277
`
`

`

`Italian Lowe Syndrome Association Formiggiana, Italy, Sept. 6-9, 2007 (platform)
`International Lowe Syndrome Meeting, London, UK, December 7, 2007
`World Parkinson’s Congress, Glasgow, UK, September 2010
`
`NATIONAL
`President's Council on Bioethics November 16, 2006(Platform)
`Alzheimer's Association Medical Scientific Advisory Council Research Symposium.
`Stanford University, June 5, 2007 (Platform)
`Society for Neuroscience, December 2008, (Poster)
`Lowe Syndrome Association, Orlando, FL, June 26-28, 2008 (Platform)
`American College of Medical Genetics, March 2009 (platform)
`American Society of Human Genetics, October 2010 (Poster)
`American Society for Cell Biology Satellite Meeting on Cell Biology of Lowe Syndrome,
`San Diego, December 2009 (Platform)
`American Society for Cell Biology (Poster) December 2009
`
`2004
`2004
`2004
`2004
`
`2004
`2004
`2005
`2005
`2005
`2005
`
`2005
`2005
`
`2005
`2005
`
`2006
`2006
`
`2006
`2006
`
`REGIONAL AND OTHER INVITED PRESENTATIONS
`2004
`University of Western Ontario, London, ON, Canada
`2004
`Bruce Rapaport Symposium, Maimonides Medical Center, Haifa, Israel
`2004
`University College London and Guy’s and St. Thomas’ Hospital Medical
`School
`Columbia College of Physicians and Surgeons, New York, NY
`Fox-Chase Cancer Center, Philadelphia, PA
`Thomas Jefferson University School of Medicine, Philadelphia, PA
`Short Course in Medical and Mammalian Genetics, Jackson Lab, Bar Harbor,
`ME.
`American Medical Writers’ Association.
`University of California Program in Human Genetics, San Francisco, CA
`Astra-Zeneca Neurodegeneration meeting Scottsdale, AZ
`University of California, Irvine
`Children’s Hospital of Philadelphia
`Short Course in Medical and Mammalian Genetics, Jackson Lab, Bar Harbor,
`ME.
`Gordon conference on Human Molecular Genetics and Genomics
`Brigham and Women’s Hospital, Harvard Medical School continuing Medical
`Education Course in Genetics
`Brigham and Women’s Hospital Medical Grand Rounds
`Cold Spring Harbor Laboratory Banbury Conference on mitochondria in
`neurodegeneration and aging
`The Parkinson’s Institute Annual Retreat Asilomar, CA April 21, 2006
`Short Course in Medical and Mammalian Genetics, Jackson Lab, Bar Harbor,
`ME.
`National Genetic Policy Summit Washington, D.C. September 20, 2006
`BMS Graduate Program Retreat, Granlibakken, Lake Tahoe, CA, October 14,
`2006
`UCSF Medical Grand Rounds (Moffitt/Long) December 7, 2006
`UCSF Department of Neurology Frontiers (Grand Rounds), February 7, 2007
`
`2006
`2007
`
`
`
`6
`
`Ariosa Exhibit 1038, pg. 6
`IPR2013-00277
`
`

`

`2007
`2007
`2007
`2007
`
`2007
`2007
`2007
`2007
`2007
`2007
`2008
`2008
`
`2008
`2008
`2008
`2008
`2008
`2009
`2009
`2009
`
`2009
`
`2009
`2010
`2010
`2010
`2010
`
`2010
`2010
`2010
`2012
`2012
`
`University of New Mexico Cancer Center, March 2007
`Gladstone Institutes, May 2007
`San Francisco Veterans Administration, Medical Grand Rounds
`Short Course in Medical and Mammalian Genetics, Jackson Lab, Bar Harbor,
`ME.
`GME Grand Rounds, UCSF,
`American Bar Association Continuing Education, South San Francisco, CA,
`Van Andel Institute, Grand Rapids, MI
`Inositide Signaling, Janelia Farms (HHMI)
`NHGRI Workshop on Personalized Medicine, Bethesda, MD
`UCSF Research Retreat on Parkinson Disease
`Gallo Institute, Emeryville, CA
`Short Course in Medical and Mammalian Genetics, Jackson Lab, Bar Harbor,
`ME.
`National Human Genome Research Institute, Bethesda, MD
`Michael J. Fox Foundation Therapeutics Conference, Chicago, IL
`Kaiser Office of Research, Oakland, CA
`University of California, San Diego
`University of Texas Southwestern Dallas, TX,
`San Francisco Veterans Hospital Medical Grand Rounds, February 2009
`UCSF Pediatric Grand Rounds
`Invited Keynote Speaker, Bowes Genetics Award, Harvard Partners, Boston,
`Short
`Short Course in Medical and Mammalian Genetics, Jackson Lab, Bar Harbor,
`ME.
`Michael J. Fox Foundation Conference, New York, NY,
`Medical Grand Rounds, Moffett-Long
`Genetics Rounds, Kaiser Permanente, San Francisco, CA
`Medical Grand Rounds, San Francisco General Hospital
`Short Course in Medical and Mammalian Genetics, Jackson Lab, Bar Harbor,
`ME.
`Renal Grand Rounds, UCSF School of Medicine
`Grand Rounds, Dept. of Neurosurgery, UCSF
`Radiation Oncology Conference, UCSF School of Medicine
`Medical Grand Rounds, Dept. of Medicine, San Francisco General Hospital
`25th Anniversary Symposium, Dept. of Molecular and Human Genetics, Baylor
`College of Medicine
`
`
`CME COURSES ATTENDED
`
`2010
`
`California Physician Update Pain: Current Understanding of Assessment and
`Management, Self-Directed Learning on the Internet
`2011-12 Genomic Medicine, El Camino Hospital
`
`GOVERNMENT and OTHER PROFESSIONAL SERVICE
`1985
`Special Study Section on Linkage Analysis in Alzheimer's Disease, NIA
`1986
`Camden Cell Repository Advisory Committee, NIGMS
`
`
`
`7
`
`Ariosa Exhibit 1038, pg. 7
`IPR2013-00277
`
`

`

`2001
`2002
`2002
`2002
`2003-08
`
`RFA: Data Management of Mapping and Sequencing Information NIGMS
`1987
`RFA: Program Projects on Rett's Syndrome, NICHD.
`1987
`1987-91 Genetic Basis of Disease, NIGMS. regular member
`1988
`RFA: Mapping and Sequencing Human and Representative Genomes NIGMS
`1989
`RFA: SBA applications for Genome Analysis, NHGRI
`1990
`RFA: SBA applications for Genome Analysis, NHGRI
`1990
`Special Study Section, Division of Research Grants, NHGRI
`1991
`Site Visitor, Genome Center Application, Duke University, NHGRI
`1992-96 Human Genome Research Study Section, regular member
`1994
`Chair, Site visit, Genome Center Application, Washington University, NHGRI
`1997
`NIMH Genetics and Mental Disorders Planning Committee, NIMH
`1998
`NIMH Intramural Research Planning Group on Genetics, NIMH
`1998
`Neurogenetics Planning Group, NINDS
`1998
`Model Organisms Database Workshop, NHGRI
`1998-00 Mammalian Genetics Study Section, regular member
`1998
`Model Organisms Database Workshop, NHGRI
`2000
`Member, Advisory Panel on Genomics for Office of AIDS Research, NHGRI
`2001
`GRASPP panel on sequencing other whole genomes, NHGRI
`2001
`Chair, Subgroup on Genotyping Methods, SNP Mapping Advisory Committee
`NHGRI
`Site Visit to Review Department of Human Genetics, University of Michigan
`Consultant for Department of Genetics, University of North Carolina
`Haplotype Mapping RFA Review Committee, NHGRI
`Canadian Institutes for Health Research, Genetics Strategy meeting
`External Advisory Board, COBRE Program in Neuroscience, University of
`North Dakota
`Site Visit, NIA DIR.
`2003
`Udall Center Review, NINDS
`2003
`Haplotype Mapping RFA Review Committee, NHGRI
`2004
`2005-07 Working Group, National Chemical Genomics Center, NHGRI
`2006-
`NCBI/NLM Working Group, dbGAP Implementation, NHGRI
`2006-
`Technical Contract Review for Pharmacological agents in Parkinson disease
`(CINAPS), NINDS
`Site Visit to Review Department of Genetics, University of Alabama,
`Birmingham
`Bioethics of Biobank Studies, Ontario Genome Center, Toronto, Canada
`Site visit to review Scientific Director of NHGRI, NHGRI
`California Technology Assessment Forum of Blue Cross-Blue Shield
`Foundation on utility of genotype-directed warfarin dosing
`2010-now Medical Genetics Working Group, NCBI/NLM/NIH
`2012-now Returning Incidnetal Genomic Findings to Patients Working Group, ACMG
`
`
`Grant Reviews for Private Foundations
`2006
`Michael J. Fox Foundation Fast-Track Grant Reviews
`2006
`Parkinson’s Study Group Clinical Grant Applications Reviews
`
`2007
`
`2007
`2008
`2008
`
`
`
`8
`
`Ariosa Exhibit 1038, pg. 8
`IPR2013-00277
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`

`

`Simons Foundation Reviews for grants in Autism Research
`2007
`2010-now March of Dimes Basil O’Connor Grant review Panel
`
`UNIVERSITY AND PUBLIC SERVICE
`
`UCSF CAMPUS-WIDE
`
`2008-2009
`2008-now
`
`
`Co-Director, Demystifying Medicine Lecture Series, UCSF
`UCSF Chancellor’s Council
`
`SCHOOL OF MEDICINE
`
`2006-2007
`
`Search Committee for Division Chief, Pediatric Genetics, Dept. of
`Pediatrics
`Co-Chair, Search Committee for Psychiatric/Behavioral Genetics
`recruitment
`Search Committee for Division Chief, Maternal-Fetal Medicine, Dept. of
`Ob/Gyn
`Search Committee for Pediatric Neurologist, Department of Neurology
`Chair, Search Committee for Pediatric Genetics Faculty, Department of
`Pediatrics
`Search Committee for Statistical Geneticist, the Gallo Institute and Dept. of
`Neurology, UCSF.
`Search Committee for new Chairman of Pediatrics
`Search Committee for geneticists for the Cardiovascular Research Institute
`(Co-Chair)
`Search Committee for faculty for the Neonatal Brain Research Institute
`(Chair)
`School of Medicine Committee on Student Welfare
`School of Medicine Admissions Committee
`
`2006-2008
`
`2007-2008
`
`2007-2008
`2008-2010
`
`2008-2010
`
`2009-
`2009-
`
`2009-
`
`2009-
`2009-
`
`SCHOOL OF PHARMACY
`
`2006-2007
`2007-2008
`
`Search Committee for Joint Pharmaceutical Sciences/IHG recruitment
`Search Committee for Genetics in Clinical Pharmacy, School of Pharmacy
`
`DEPARTMENTAL SERVICE:
`
`2007
`2007-now
`
`2010-now
`
` PUBLIC SERVICE:
`
`
`Search Committee for Nephrology Division Chief, Department of Medicine.
`Interviewer for internal medicine residency applicants, Department of
`Medicine, UCSF
`Director, Molecular Medicine Program
`
`
`
`9
`
`Ariosa Exhibit 1038, pg. 9
`IPR2013-00277
`
`

`

`1996
`
`1999
`
`2003
`
`Organized and taught courses for the public on genetics and genomics for the
`Smithsonian Associates Program, Washington DC.
`Organized and taught courses for the public on genetics and genomics for the
`Smithsonian Associates Program, Washington DC.
`Organized and taught courses for the public on genetics and genomics for the
`Smithsonian Associates Program, Washington DC.
`Advances in Parkinson Disease Genetics, NINDS-sponsored press conference
`2005
`2003-2006 DNA Day Outreach Participant
`2006
`Public Outreach on Genomic Medicine, Toronto, Canada
`2007
`Judge, Biotech Educator Awards
`2008
`Wellness Lecture for the UCSF Development Office on Personalized Medicine
`and Genetics
`Numerous interviews with the lay press on Direct-to-Consumer Genetics
`testing
`Science Café Interview for UCSF Public Affairs
`UCSF Minimedical School Lecture “’It’s All in the Family’ – Genetics in
`Medicine”
`Arrhythmia Family Outreach Day talk “Introduciton to Genetics”
`UCSF Minimedical School Lecture “When Cancer Runs in Families”
`
`2008
`
`2008
`2010
`
`2011
`2011
`
`
` SUMMARY OF SERVICE ACTIVITIES
`
`I have served on numerous faculty search committees for the Schools of Medicine
`and Pharmacy, serving as chair for some of the committees. I am also very active in
`admissions committees for medical students and interviewing applicants for the internal
`medicine residency, particularly those with an interest in the Molecular Medicine Program.
`
`I have a long track record of public education in Genetics.
`
`TEACHING and MENTORING
`FORMAL SCHEDULED CLASSES FOR UCSF STUDENTS:
`Teaching Contributio Units
`Qtr Academic Yr Course No. & Title
`(hrs.)
`Small Group Leader 2
`
`F
`
`2005-2006
`
`Prologue IDS 101
`
`Class Size
`
`12
`
`S
`
`2005-2006
`
`Brain Mind Behavior IDS 104 Small Group Leader 2
`
`W 2005-2006
`
`Life Cycle IDS 107
`
`Small Group Leader 2
`
`2006-2007
`
`Prologue IDS 101
`
`Small Group Leader 2
`
`2006-2007
`
`Organs IDS 102
`
`Lecturer
`
`2
`
`2006-2007
`
`Organs IDS 102
`
`Small Group Leader 2
`
`F
`
`F
`
`F
`
`
`
`12
`
`12
`
`12
`
`120
`
`12
`
`10
`
`Ariosa Exhibit 1038, pg. 10
`IPR2013-00277
`
`

`

`S
`
`2006-2007
`
`Brain Mind Behavior IDS 104 Small Group Leader 2
`
`W 2006-2007
`
`Life Cycle IDS 107
`
`Small Group Leader 2
`
`F
`
`F
`
`F
`
`F
`
`S
`
`2007-2008
`
`Prologue IDS 101
`
`Small Group Leader 2
`
`2007-2008
`
`Organs IDS 102
`
`Lecturer
`
`2
`
`2007-2008
`
`2007-2008
`
`2007-2008
`
`Small Group Leader 2
`
`Organs IDS 102
`Mechanisms, Methods and
`Malignancies IDS 106
`Brain Mind Behavior IDS 104 Small Group Leader 2
`
`Small Group Leader 2
`
`W 2007-2008
`
`Life Cycle IDS 107
`
`Small Group Leader 2
`
`2007-2009
`
`Genetics 224
`
`Seminar Leader
`
`6
`
`2008-2009
`
`Prologue IDS 101
`
`Small Group Leader 2
`
`2008-2009
`
`Organs IDS 102
`
`Lecturer
`
`2
`
`120
`
`12
`
`12
`
`12
`
`120
`
`12
`
`12
`
`12
`
`12
`
`8
`
`12
`
`12
`
`12
`
`12
`
`12
`
`120
`
`12
`
`120
`
`12
`
`12
`
`12
`
`11
`
`F
`
`F
`
`F
`
`F
`
`F
`
`S
`
`2008-2009
`
`2008-2009
`
`2008-2009
`
`Small Group Leader 2
`
`Organs IDS 102
`Mechanisms, Methods and
`Malignancies IDS 106
`Brain Mind Behavior IDS 104 Small Group Leader 2
`
`Small Group Leader 2
`
`W 2008-2009
`
`Life Cycle IDS 107
`
`Small Group Leader 2
`
`W 2008-2009 Metabolism and Nutrition IDS 10Lecturer
`
`1
`
`2009-2010
`
`Prologue IDS 101
`
`Small Group Leader 2
`
`2009-2010
`
`Organs IDS 102
`
`Lecturer
`
`2
`
`2009-2010
`
`2009-2010
`
`2009-2010
`
`Small Group Leader 2
`
`Organs IDS 102
`Mechanisms, Methods and
`Malignancies IDS 106
`Brain Mind Behavior IDS 104 Small Group Leader 2
`
`Small Group Leader 2
`
`F
`
`F
`
`F
`
`F
`
`S
`
`
`
`Ariosa Exhibit 1038, pg. 11
`IPR2013-00277
`
`

`

`W 2009-2010
`
`Life Cycle IDS 107
`
`Small Group Leader 2
`
`W 2009-2010 Metabolism and Nutrition IDS 10Lecturer
`
`2010-2011
`
`Organs IDS 102
`
`Lecturer
`
`1
`
`3
`
`F
`
`F
`F
`
`S
`
`2010-2011
`2010-2011
`
`2010-2011
`
`W 2010-2011
`
`W 2010-2011
`
`F
`
`F
`
`F
`
`F
`
`S
`
`2011-2012
`
`2011-2012
`
`2011-2012
`
`2011-2012
`
`2011-2012
`
`W 2011-2012
`
`Small Group Leader 2
`Small Group Leader 2
`
`Organs IDS 102
`Mechanisms, Methods and
`Malignancies IDS 106
`Brain Mind Behavior IDS 104 Small Group Leader 2
`Small Group Leader 2
`
`Life Cycle IDS 107
`
`Metabolism and Nutrition IDS 10
`
`Prologue IDS 101
`
`Organs IDS 102
`
`Organs IDS 102
`Mechanisms, Methods and
`Malignancies IDS 106
`Brain Mind Behavior IDS 104
`
`Lecturer
`
`1
`
`Small Group Leader 2
`
`Lecturer
`
`3
`
`Small Group Leader 2
`
`Small Group Leader 2
`
`Small Group Leader 2
`
`Small Group Leader 2
`
`Lecturer
`
`Lecturer
`
`1
`
`2
`
`Life Cycle IDS 107
`W 2011-2012 Metabolism and Nutrition
`IDS 103
`Graduate Education in Medical
`Science (GEMS)
`
`W 2011-2012
`
`
`
`12
`
`120
`
`120
`
`12
`12
`
`12
`
`12
`
`120
`
`12
`
`120
`
`12
`
`12
`
`12
`
`12
`
`120
`
`28
`
`POSTGRADUATE AND OTHER COURSES
`2008 CME, Dept. of Medicine, Electrophysiology Update, gave 1 lecture
`2009 CME, Dept. of Medicine, Occupational Medicine, gave 1 lecture
`2009 CME, Dept. of Pediatrics, Update on Personalized Medicine, gave 1 lecture.
`2010 CME, Dept of Otolaryngology, Update on Head and Neck Surgery, gave 1 lecture.
`
`PREDOCTORAL STUDENTS SUPERVISED OR MENTORED:
`
`
`Dates
`
`Name
`
`Program or
`
`Role
`
`Current Position
`
`
`
`12
`
`Ariosa Exhibit 1038, pg. 12
`IPR2013-00277
`
`

`

`1995
`
`1997
`
`Laura Pomerance
`
`Rachel Perline
`
`1999-2001 Sotiria Sotiriou
`
`2005-2010 Susan Bothwell
`
`2006
`
`Adam Hoagland
`
`1984-1989 Dorothy Reilly
`
`1985-1991 Diane Merry
`
`1991-1996
`
`Isabelle Olivos
`
`1992-1995 Pasi Janne
`
`School
`Sidwell
`Friends School
`Olivette High
`School
`University of
`Edinburgh
`Lafayette
`College
`Colorado
`College
`University of
`Pennsylvania
`
`University of
`Pennsylvania
`
`University of
`Pennsylvania
`
`MD/PhD
`University of
`Pennsylvania
`
`Research Advisor
`
`?
`
`Research Advisor Medical Resident, NYU
`
`Research Advisor
`
`Postdoctoral Fellow, U of
`Pennsylvania
`Research Advisor Applying to Medical
`School
`Research Advisor Graduate School, UC
`Berkeley
`Novartis Pharmaceuticals
`Bioinformatician
`
`Thesis Advisor
`
`Thesis Advisor
`
`Thesis Advisor
`
`Thesis Advisor
`
`Professor, Thomas
`Jefferson School of
`Medicine
`Scientist, GeneDx
`Laboratory
`
`Professor, Harvard
`Medical School
`
`
`
`13
`
`Ariosa Exhibit 1038, pg. 13
`IPR2013-00277
`
`

`

`1989-1992
`
`Jeannie Lee
`
`MD/PhD
`University of
`Pennsylvania
`1993-1996 Sudha Srinivasan University of
`Pennsylvania
`
`George
`Washington
`University
`Johns Hopkins
`University
`Rotation in
`BMS, UCSF
`Research
`Rotation
`Rotation in
`BMS, UCSF
`
`2001-2005 Leslie Farber
`
`2003-2008 Sotiria Sotiriou
`
`2007
`
`Karen Ring
`
`2009
`(summer)
`2009
`
`Sam Brondfield
`
`Mike Andos
`
`Thesis Advisor
`
`Professor, Harvard
`Medical School
`
`Thesis Advisor
`
`NIH, Program Officer
`
`Thesis Advisor
`
`Home raising children
`
`Thesis Advisor
`
`Rotation Advisor
`
`Postdoctoral Fellow
`U of Pennsylvania
`Graduate student
`BMS, UCSF
`Rotation Advisor Medical Student, UCSF
`
`Rotation Advisor
`
`Graduate student
`BMS, UCSF
`
`
` POSTDOCTORAL FELLOWS AND RESIDENTS DIRECTLY SUPERVISED OR MENTORED:
`[list all, defining research or clinical supervision; give dates; list current position if known;
`describeMentoring role, e.g. personal advisor, research advisor, career advisor, etc.]
`
`Name
`Dates
`1985-1988 Anne Maddalena
`
`Faculty role
`Research Advisor
`
`Current Position
`Scientist, GeneDx
`
`Fellow
`Post-Doc
`researcher
`Genetics
`Fellow
`Genetics
`Fellow
`
`1987-1990 Max Muenke
`
`86-90
`
`Rhonda Schnur
`
`1989-1991 Alessandra
`Murgia
`1991-1993 Anne-Marie
`Leahey
`
`Post-Doc
`Researcher
`Oncology
`Fellow
`
`1992-1994 Rebecca Oakey
`
`Post-Doc
`Researcher
`
`Research Advisor
`
`Research Advisor Chief, Medical Genetics
`Branch, NHGRI/NIH
`Research Advisor Attending Genetics, Cooper
`Hospital, Camden,
`New Jersey
`Professor Pediatrics,
`University of Padova, Italy
`Research Advisor Asst. Professor of Oncology
`Children’s Hospital of
`Philadelphia
`(Currently homemaker
`caring for
`children)
`Research Advisor Lecturer in Genetics,
`Department of Medical &
` Molecular Genetics, Guy’s
`
`
`
`14
`
`Ariosa Exhibit 1038, pg. 14
`IPR2013-00277
`
`

`

`1993-1996 Christian
`Lavedan
`1993-1997 Sharon Suchy
`
`1994-1995
`
`Ichiro Okabe
`
`1995-1900 Ti Lin
`
`1996-1998 Marlene
`Dressman
`1996-1998 Roger Bascom
`
`1996-1999 Lei Bi
`
`1996-2001 Elina Hellsten
`
`1999-2001 Suzana Gispert
`
`2002-2005 Felicia Eason
`Forbes
`1999-2006 Deborah Cabin
`
`1999-2006 Ornit Chiba-
`Falek
`
`1999-2006 Nelson Cole
`
`2000-2007 Christopher Ellis
`
`04-07
`
`05-10
`
`2010-
`
`Melinda
`McFarland
`Valerie Drews
`
`Ianai Fishbein
`
`Post-Doc
`Researcher
`Post-Doc
`Researcher
`
`
`Post-Doc
`Researcher
`Post-Doc
`Researcher
`Post-Doc
`Researcher
`Post-Doc
`Researcher
`Post-Doc
`Researcher
`Post-Doc
`Researcher
`Post-Doc
`Researcher
`Post-Doc
`Researcher
`
`Post-Doc
`Researcher
`
`Post-Doc
`Researcher
`
`Post-Doc
`Researcher
`Post-Doc
`Researcher
`Post-Doc
`Researcher
`Post-Doc
`Researcher
`
`King’s & St Thomas’
`School of Medicine,
`London, UK
`Research Advisor Head of Discovery, Vanda
`Pharmaceuticals
`Scientist, GeneDx
`
`Research Advisor
`
`Research Advisor Dept of Pediatrics
`Haga Red Cross Hospital,
`Japan
`Program Officer, NINDS
`
`Research Advisor
`
`Research Advisor
`
`Scientist, Vanda
`Pharmaceuticals
`Research Advisor Research Fellow, University
`of Alberta
`Research Advisor Research Scientist, FDA
`
`Research Advisor Corning Sciences
`
`Research Advisor
`
`Research Advisor
`
`Staff Scientist, Goethe
`University, Frankfurt
`Public School Science
`Teacher
`Research Advisor Assistant Professor,
`McLaughlin Research
`Institute, Great Fall, MT
`Research Advisor Assistant Professor, Duke
`University Medical
`School
`Research Advisor Research Associate, NICHD
`Division of Intramural
`Research
`Food and Drug
`Administration, CBER
`Research Advisor Ctr for Food Safety &
`Applied Nutrition/FDA
`Scientist, Catalyst
`Biosciences
`Current
`
`Research Advisor
`
`Research Advisor
`
`
`
`
`
`15
`
`Ariosa Exhibit 1038, pg. 15
`IPR2013-00277
`
`

`

`2007
`
`INFORMAL TEACHING: [Describe nature of this teaching since last advancement]
`2006
`
`Sue-Ann Lee (Muchowski Lab) Prelim Committee and Thesis Committee
`2007
`Internal Medicine Resident Education Sessions on Genetics at Moffett-Long,
`SFGH and SFVA Hospitals (3 hours)
`Education Sessions on Genetics and Individualized Medicine for Fellows in the
`Division of General Internal Medicine (2 hours)
`Beth Theusch (Gitschier Lab) (Chair of thesis Committee)
`
`2007
`Angela Sia (Muchowski Lab) Prelim Committee
`
`2007
`2007-2008 Supervise Journal Club presentations in BMS 255 Genetics course (4 hours)
`2008-2009 Facilitator for BEST Microteaching workshop, Academic Career Development
`Office, UCSF Office of Career and Professional Development
`2007-now Resident teaching through regular attendance at the weekly M&M Conference
`in the Department of Medicine (30 hours)
`2009-2010 Familial Cancer Syndromes for Oncology Fellows, 1 hour lecture
`2009-2010 Three 2-hour lectures for Cal State Stanislaus Genetic Counseling Students
`2009-2010 Facilitator for BEST Microteaching workshop, Academic Career Development
`Office, UCSF Office of Career and Professional Development
`Ryan Devon (Ptacek lab) Thesis Committee
`
`2009
`Ian Kratter (Finkbeiner Lab) Prelim Committee
`
`2010
`Todd Logan, BMS Prelim Exam Committee (Chair)
`
`2010
` Michael Andos, BMS Prelim Exam Committee (Chair)
`2010
`
`Jonathan Russell, Prelim Exam Committee (Chair)
`2011
`2010-2011 I organize and participate in a bi-weekly case presentation/journal club for two
`hours every other Friday morning to which Medical Students in the Molecular
`Medicine Pathway, MSTP students, and medicine and pediatric residents come
`to hear about an interesting case and then review recent articles presenting
`novel basic or translational science applicable to the case.
`
`
`FACULTY MENTORING
`
`FACULTY MENTORED: [list all; list the current position of the faculty mentored; list
`dates; describe Mentoring role, e.g. assigned faculty Mentor, informal career advisor,
`personal advisor, research/grant review, etc.]
`
`
`Dates
`
`Name
`
`Position while
`Mentored
`2006-2010 Wen-Chi Hsue Asst. Prof. Academic Advisor
`
`Mentoring Role
`
`Current Position
`
`Assoc. Prof., Medicine,
`UCSF
`
`
`TEACHING AIDS:
`
`
`
`
`16
`
`Ariosa Exhibit 1038, pg. 16
`IPR2013-00277
`
`

`

`Cardiovascular Genetics syllabus in Essential Core Curriculum
`Complex Trait Small Group syllabus in Essential Core Curriculum
`Metabolism and Nutrition syllabus in the Essential Core curriculum
`Heredi