`QuickLinks -- Click here to rapidly navigate through this document
`
` The following entities are wholly owned entities of Edwards Lifesciences Corporation:
`
`Page 1 of 4
`
`Exhibit 21.1
`
`Legal Entity
`Edwards Lifesciences Asset Management Corporation
`Edwards Lifesciences Corporation of Puerto Rico
`Edwards Lifesciences Financing LLC
`Edwards Lifesciences International Assignments Inc.
`Edwards Lifesciences International Holdings LLC
`Edwards Lifesciences LLC
`Edwards Lifesciences (U.S.) Inc.
`Edwards Lifesciences World Trade Corporation
`Edwards Lifesciences PVT, Inc.
`Red Hill Holding LLC
`Red Hill Insurance Corporation
`Edwards Lifesciences Austria GmbH
`Edwards Lifesciences Pty. Limited
`Edwards Lifesciences S.P.R.L.
`Edwards Lifesciences Macchi Ltda.
`Edwards Lifesciences Participacoes e Comercial Ltda.
`Edwards Lifesciences Comercio de Produtos Medico-
`Cirurgicos Ltda.
`Edwards Lifesciences (Canada) Inc.
`Edwards Lifesciences (Shanghai) Medical Products Co., Ltd.
`Edwards Lifesciences Columbia S.A.S.
`Edwards Lifesciences Czech Republic s.r.o.
`Edwards Lifesciences A/S
`Edwards Lifesciences SAS
`Edwards Lifesciences Services GmbH
`Edwards Lifesciences Hellas, EPE
`Edwards Lifesciences (India) Private Limited
`Edwards Lifesciences (Israel) Ltd.
`Edwards Lifesciences Sales (Israel) Ltd.
`Edwards Lifesciences Italia SpA
`Edwards Lifesciences (Japan) Limited
`Edwards Lifesciences Korea Co., Ltd.
`Edwards Lifesciences (Malaysia) Sdn. Bhd.
`Edwards Lifesciences Mexico, S.A. de C.V.
`BMEYE B.V.
`Edwards Lifesciences B.V.
`Edwards Lifesciences Holding B.V.
`Edwards Lifesciences (Poland) Ltd.
`Edwards Lifesciences (Portugal) Comércio e Distribuicao de
`Dispositivos Medicos, Lda.
`Edwards Lifesciences Export (Puerto Rico) Corporation
`Edwards Lifesciences (Asia) Pte., Ltd.
`Edwards Lifesciences (Singapore) Pte Ltd
`Edwards Lifesciences (Proprietary) LTD
`Edwards Lifesciences S.L.
`Edwards Lifesciences Nordic AB
`Edwards Lifesciences AG
`Edwards Lifesciences Technology S.A.R.L.
`
`State of
`Incorporation/
`Formation
`Delaware
`Delaware
`Delaware
`Delaware
`Delaware
`Delaware
`Delaware
`Delaware
`Delaware
`Delaware
`D.C.
`
`Country of
`Incorporation/
`Formation
`
`U.S.
`U.S.
`U.S.
`U.S.
`U.S.
`U.S.
`U.S.
`U.S.
`U.S.
`U.S.
`U.S.
`Austria
`Australia
`Belgium
`Brazil
`Brazil
`Brazil
`
`Canada
`China
`Columbia
`Czech Republic
`Denmark
`France
`Germany
`Greece
`India
`Israel
`Israel
`Italy
`Japan
`Korea
`Malaysia
`Mexico
`The Netherlands
`The Netherlands
`The Netherlands
`Poland
`Portugal
`
`Puerto Rico
`Singapore
`Singapore
`South Africa
`Spain
`Sweden
`Switzerland
`Switzerland
`
`http://www.sec.gov/Archives/edgar/data/1099800/000104746914001583/a2218406zex-21_...
`
`3/3/2016
`
`Edwards Exhibit 1047, pg. 1
`Edwards vs. Endoheart
`IPR2016-00300
`
`
`
`Edwards Lifesciences IPRM AG
`
`Switzerland
`
`Page 2 of 4
`
`http://www.sec.gov/Archives/edgar/data/1099800/000104746914001583/a2218406zex-21_...
`
`3/3/2016
`
`Edwards Exhibit 1047, pg. 2
`Edwards vs. Endoheart
`IPR2016-00300
`
`
`
`Page 3 of 4
`
`Legal Entity
`Edwards Lifesciences (Taiwan) Corporation
`Edwards Lifesciences (Thailand) Ltd.
`Edwards Lifesciences Saguk Urunleri Limited Sirketi
`Edwards Lifesciences Limited
`Whitland Research Limited
`
`State of
`Incorporation/
`Formation
`
`Country of
`Incorporation/
`Formation
`Taiwan
`Thailand
`Turkey
`United Kingdom
`United Kingdom
`
`http://www.sec.gov/Archives/edgar/data/1099800/000104746914001583/a2218406zex-21_...
`
`3/3/2016
`
`Edwards Exhibit 1047, pg. 3
`Edwards vs. Endoheart
`IPR2016-00300
`
`
`
`Page 4 of 4
`
`QuickLinks
`
`Exhibit 21.1
`
`http://www.sec.gov/Archives/edgar/data/1099800/000104746914001583/a2218406zex-21_...
`
`3/3/2016
`
`Edwards Exhibit 1047, pg. 4
`Edwards vs. Endoheart
`IPR2016-00300
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