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`Trichloroacetic acid, 99+%, ACS reagent
`
`~
`~
`
`MSOS Specifications Applications Categories 3D model
`
`Infrared Molfile Other grades
`
`I
`
`General
`Product Name
`
`Trichloroacet ic acid
`TCA
`
`CAS RN
`
`76-03-9 /
`
`ACD Code
`Structure
`
`MFCD00004177
`
`0 V OH
`
`Cl Cl
`
`p
`
`Molecular Formula
`
`C2 H Cl3 02
`
`Molecular weight
`
`163.39
`
`Pack size
`
`Catalog
`
`Qty / UM Price
`(USD)
`;:l' 421450025 2.5 KG
`494.90 Order Check stock
`;:l' 421451000 100 GR
`48.20 Order Check stock
`;:l' 421451000 6 x 100 GR 245.82 Order Check stock
`;:l' 421455000 500 GR
`127.50 Order Check stock
`;:l' 421455000 6 x 500 GR 650.28 Order Check stock
`
`Physical
`Density (g/cm3) 1.62
`Boiling Point (°C) 196
`Melting Point (°C) 52 - 58
`Safety
`GHS Pictogram
`
`GHS Signal Word
`
`Danger
`
`GHS H statement
`
`H314: Causes severe skin burns and eye damage
`H335: May cause respiratory irritation
`H410: Very toxic to aquatic life with long lasting effects
`GHS P statement P305 + P351 +
`P338:
`P310:
`P280:
`P301 + P330 +
`P331:
`P303 + P361 +
`P353:
`P304 + P340:
`
`IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
`do. Continue rinsing
`Immediately call a POISON CENTER or doctor/physician
`Wear protective gloves/protective clothing/eye protection/face protection
`
`IF SWALLOWED: ri nse mouth. Do NOT induce vomiting
`
`IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower
`
`IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing
`
`Categories
`
`Preparation, Purification and Analysis > Derivatization Reagents > Derlyat ization Reagents TLC > TLC Visualization Reagents
`(by application) > Steroids, Terpenes, lipids, Bile acids /
`Preparation, Purification and Analysis > Derivatization Reagents > Derivatization Reagents TLC > TLC Visualization Reagents
`(by application) > Saccharides & Lignins /
`Preparation, Purification and Analysis > Derivatization Reagents > Derivatization Reagents TLC > TLC Visualization Reagents
`(alphabetic sort) > TLC Reagents, S-Z )
`Preparation, Purification and Analysis > Derlvatization Reagents > Derivatization Reagents TLC > TLC Visualization Reagents
`(alphabetic sort) I
`Preparation, Purification and Analysis > Derlvatlzation Reagents > TLC Visualization Reagents (alphabetic sort) > TLC
`Reagents, S-Z I
`Preparation, Purification and Analysis > Derivatization Reagents > TLC Visua lization Reagents (by application) > Steroids,
`Terpenes, lipids, Bile acids /'
`Biochemicals and Reagents > Proteomics > Protein Electrophoresis > SOS-PAGE > Buffers /
`Biochemicals and Reagents > Molecular Biology > Protein Electrophoresis > SOS-PAGE > Buffers f
`FINC1IlMICA EXHIBIT 2016
`ADAMA MAKHTESHIM v. FINCHIMICA
`CASE IPR2016-00577
`
`

`
`MSDS Specifications Applications Categories 3D model Infrared Molfile Other grades
`
`Trichloroacetic acid, 99+%, ACS reagent
`
`General
`Product Name Trichloroacetic acid
`TCA
`CAS RN 76-03-9
`ACD Code MFCD00004177
`Structure
`
`Molecular Formula C2 H Cl3 O2
`Molecular weight 163.39
`Pack size
`Catalog
`
`Qty / UM Price
`(USD)
` 421450025 2.5 KG
` 494.90 Order Check stock
` 421451000 100 GR
` 48.20 Order Check stock
` 421451000 6 x 100 GR 245.82 Order Check stock
` 421455000 500 GR
` 127.50 Order Check stock
` 421455000 6 x 500 GR 650.28 Order Check stock
`
`Physical
`Density (g/cm³) 1.62
`Boiling Point (°C) 196
`Melting Point (°C) 52 - 58
`Safety
`GHS Pictogram
`
`^
`
`^
`
`^
`
`GHS Signal Word Danger
`GHS H statement H314: Causes severe skin burns and eye damage
`H335: May cause respiratory irritation
`H410: Very toxic to aquatic life with long lasting effects
`GHS P statement P305 + P351 +
`P338:
`P310:
`P280:
`P301 + P330 +
`P331:
`P303 + P361 +
`P353:
`P304 + P340:
`
`IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to
`do. Continue rinsing
`Immediately call a POISON CENTER or doctor/physician
`Wear protective gloves/protective clothing/eye protection/face protection
`
`IF SWALLOWED: rinse mouth. Do NOT induce vomiting
`
`IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower
`
`IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing
`
`Categories
`
`Preparation, Purification and Analysis > Derivatization Reagents > Derivatization Reagents TLC > TLC Visualization Reagents g
`
`^
`
`(by application) > Steroids, Terpenes, Lipids, Bile acids
`Preparation, Purification and Analysis > Derivatization Reagents > Derivatization Reagents TLC > TLC Visualization Reagents
`(by application) > Saccharides & Lignins
`Preparation, Purification and Analysis > Derivatization Reagents > Derivatization Reagents TLC > TLC Visualization Reagents
`(alphabetic sort) > TLC Reagents, S-Z
`Preparation, Purification and Analysis > Derivatization Reagents > Derivatization Reagents TLC > TLC Visualization Reagents
`(alphabetic sort)
`Preparation, Purification and Analysis > Derivatization Reagents > TLC Visualization Reagents (alphabetic sort) > TLC
`Reagents, S-Z
`Preparation, Purification and Analysis > Derivatization Reagents > TLC Visualization Reagents (by application) > Steroids,
`Terpenes, Lipids, Bile acids
`Biochemicals and Reagents > Proteomics > Protein Electrophoresis > SDS-PAGE > Buffers
`Biochemicals and Reagents > Molecular Biology > Protein Electrophoresis > SDS-PAGE > Buffers
`
`1
`
`

`
`Preparation, Purification and Analysis > Derivatization Reagents > TLC Visualization Reagents (by application) > Saccharides
`& Lignins
`Biochemicals and Reagents > Plant Biotechnology > Plant Proteomics > Protein Electrophoresis > SDS-PAGE > Buffers
`Preparation, Purification and Analysis > Routine Reagents > ACS Grade
`Functional Reagents > Organic Acids
`Biochemicals and Reagents > Denaturation > Acids and Bases
`Biochemicals and Reagents > Denaturation > Alphabetical
`Biochemicals and Reagents > Common Reagents
`Preparation, Purification and Analysis > Analytical Reagents for General Use
`
`Applications
`
`^
`
`Caveat
`Function Transformation Type
`Reagent Organic Acid
`Catalyst Variety of uses particularly as dichlorocarbene precursor,
`diazotization of amines, synthesis of porphyrins, addition of
`trichloromethyl anion into alkenes and aromatic systems.
`
`Reference
`SC 1990, 20, 1967; OSC
`1973, 5, 54; JHC 1990, 27,
`1657; CC 1983, 140.
`
`^
`
`Other
`Infrared Show
`Parameter EINECS
`Solubility
`
`200-927-2
`Solubility in water: 120 g/100 mL (20°C) Solubility in other solvents: SOLUBLE IN ALCOHOL AND ETHER,
`CARBON TETRACHLORIDE
`synthetic
`Randolph B. Caldwell et al.: Simple and Reliable Method To Precipitate Proteins from Bacterial Culture
`Supernatant, Appl. Environ. Microbiol., 2004, 70(1), 610-12.
`Roberto M. Aguilar et al.: Precipitation of Dilute Chromatographic Samples (ng/ml) Containing Interfering
`Substances for SDS-PAGE, Anal. Biochem., 1999, 267, 344-50.
`T. Sivaraman et al.: The Mechanism of 2,2,2-Trichloroacetic Acid-Induced Protein Precipitation, J. Prot.
`Chem., 1997, 16(4), 291-7.
`Byung Joon Hwang et al.: Trichloroacetic Acid Precipitation by Ultracentrifugation to Concentrate Dilute Protein
`in Viscous Solution, BioTechniques, 1996, 20(6), 982-4.
`02,206
`
`Origin
`References:
`Literature
`References:
`Literature
`References:
`Literature
`References:
`Literature
`Reference:
`Beilstein
`Reference: Fieser 01,1194; 02,425; 04,520; 15,168
`Reference: Merck 15,9792
`3D model Show
`
`2