`
`D. P. Curran
`
`CURRICULUM VITAE
`
`Name:
`Address:
`
`Dennis Patrick Curran
`Department of Chemistry
`University of Pittsburgh
`Pittsburgh, PA 15260
`
`Updated:
`
`8/15/16
`
`Phone:
`
`(412) 624-8240 (Office)
`(412) 661-0566 (Home)
`(412) 624-9861 (FAX)
`curran@pitt.edu
`email:
`http://radical.chem.pitt.edu/
`websites:
`https ://en. wikipedia.org/wiki/Dennis P. Curran
`
`PERSONAL
`
`Born:
`Citizenship:
`
`June 10, 1953,Easton,PA
`United States of America
`
`EDUCATION
`
`Boston College
`Chestnut Hill, Massachusetts
`Sept., 1971 to June, 1975
`B .S. Chemistry, Magna Cum Laude
`
`University of Rochester
`Rochester, New York
`Matriculated Sept., 1975
`Ph.D. June, 1979
`
`University of Wisconsin
`Madison, Wisconsin
`Postdoctoral Fellow
`August, 1979-July, 1981
`
`EMPLOYMENT
`
`Department of Chemistry
`University of Pittsburgh
`Pittsburgh, PA 15260
`Assistant Professor, 1981-1986; Associate Professor, 1987, Full Professor, 1988-1995
`Distinguished Service Professor and Bayer Professor, 1996-present
`
`SOCIETIES AND HONORS
`
`Chaire Joliot, Ecole Superieure de Physique et de Chimie Industrielles (ESPCI), Paris, 2015
`American Chemical Society Ernest Guenther Award in the Chemistry of Natural Products, 2014
`Visiting Professor, Osaka Prefecture University, Japan, 2011
`Visiting Professor, Westfalische Wilhelms-Universitat, Munster, Germany, 2011
`Honorary Doctorate, Universite Pierre et Marie Curie (UPMC), Paris, France, 2010
`Fellow of the American Chemical Society, Inaugural Class of 2009
`Provost's Award for Excellence in Mentoring, University of Pittsburgh, 2009
`Chaire d'excellence, Agence National de la Recherche (ANR), France, 2009-2010
`American Chemical Society Award for Creative Work in Fluorine Chemistry, 2008
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`PAGE -1-
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`FINCHIMICA EXHIBIT 2020
`ADAMA MAKHTESHIM v. FINCHJMICA
`CASE IPR2016-00577
`
`
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`Curriculum Vitae
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`
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`D. P. Curran
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`Most Cited Paper in Tetrahedron, 2005–2008 (#355, a review on fluorous solid phase extraction)
`University of Pittsburgh Innovator Award, 2007
`Harry and Carol Mosher Award, Santa Clara Valley Section, ACS, 2007
`Blaise Pascal International Research Chair, Préfecture de la Région d’Ile-de-France (Paris), 2007-2008
`2nd International Society of Fluorous Technology (ISOFT) Noguchi Award, 2007 (Shared with J. Gladysz)
`Ryudo Visiting Professor, Tokyo Institute of Technology, 2007
`The Pittsburgh Award, Pittsburgh Section, American Chemical Society, 2006
`Morley Medal, Cleveland Section, American Chemical Society, 2006
`National Science Foundation, Creativity Extension, 2005-2006
`National Institutes of Health (NIGMS), Merit Award, 2004-2014
`Pittsburgh Magazine, Innovator of the Year Award, 2003
`Fellow, American Association for the Advancement of Sciences, 2001
`ISI Highly Cited Researcher, among top 100 in chemistry (www.ISIHighlyCited.com), 2000-present
`Boston College Alumni Achievement Award for Excellence in Science, 2000
`American Chemical Society Award for Creativity in Organic Synthesis, 2000
`Chancellor’s Distinguished Research Award, Senior Scholar, University of Pittsburgh, 1999
`Janssen Prize for Creativity in Organic Synthesis, 1998
`Humboldt Senior Research Awardee, 1998-2002
`University Visiting Professor, Kyushu University, 1996
`Fuson Professor, University of Illinois, 1995
`Reichstein Professor, University of Basel, 1994
`Japan Society for the Promotion of Science Fellow, 1994
`ICI Award for Excellence in Chemistry, 1990
`President’s Distinguished Research Award, Junior Scholar, University of Pittsburgh, 1989
`American Chemical Society Cope Scholar Award, 1988
`Research Career Development Award, National Institutes of Health, 1987-1992
`Dreyfus Teacher-Scholar Awardee, 1986-1991
`Alfred P. Sloan Foundation Fellow, 1985-1987
`Merck Faculty Development Grantee, 1986-1988
`Eli Lilly Grantee, 1985-1987
`Dreyfus Grant for Newly Appointed Young Faculty in Chemistry, 1981-1986
`National Institutes of Health (NCI), Postdoctoral Fellow, University of Wisconsin, 1979-1980
`Elon Huntington Hooker Fellow and Sherman Clarke Fellow, University of Rochester, 1977-1979
`President, University of Rochester Chemistry Graduate Association, 1977-78
`
`
`
`OUTSIDE ACTIVITIES
`
`
`Advisory Boards
`European Journal of Organic Chemistry, Advisory Board, 2011-present
`Arkivoc, Honorary Advisory Board, 2006-present
`Organic Syntheses, Inc., Member of the Corporation, Editorial Advisory Board, 2006-present
`Beilstein J. Org. Chem., Advisory Editorial Board, 2005-present
`J. Am. Chem. Soc. Editorial Advisory Board, 2005-2008
`Advanced Synthesis & Catalysis, Editorial Advisory Board, 2001-2013
`Organic Reactions, Editorial Advisory Board, 2001-present
`Journal of Combinatorial Chemistry, Editorial Advisory Board, 1999-2005
`Tetrahedron Board of Consulting Editors, 1998-present
`Tetrahedron International Advisory Board, 1992-1995
`Progress in Heterocyclic Chemistry, Editorial Advisory Board, 1999-2001
`Chemical Society Perkin: Journals, Editorial Advisory Board, 1992-2003
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`PAGE -2-
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`Curriculum Vitae
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`
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`D. P. Curran
`
`
`Meetings Organized
`International Advisory Board, ISoFT’17 (International Society of Fluorous Technologies), Boston, MA,
`2017
`International Advisory Board, ISoFT’15 (International Society of Fluorous Technologies), Milan, Italy,
`2015
`International Organizing Committee, 13th EUCHEM Conference on Organic Free Radicals (ECOFR),
`Prague, Czech Republic, 2014.
`International Organizing Committee, 5th Pacific Symposium on Radical Chemistry (PSRC-5), Shirahama,
`Japan, 2011
`International Advisory Committee, ISoFT’11 (International Society of Fluorous Technologies), Hong
`Kong, China, 2011
`US-Co-organizer, Japan-US Workshop on Green Chemistry, Honolulu, HI, 2010
`Chair, ISoFT’09 (International Society of Fluorous Technologies), Jackson Hole, Wyoming, 2009
`Organizing Committee, 19th International Symposium of Fluorine Chemistry (ISFC), Jackson Hole,
`Wyoming, 2009
`Advisory Committee, 10th International Symposium for Organic Free Radicals, and 3rd Pacific
`Symposium on Radical Chemistry, Heron Island, Australia, 2008
`International Advisory Committee, ISoFT’07 (International Society of Fluorous Technologies),
`Yokohama, Japan, 2007
`International Advisory Committee, EUCHEM Free Radical Meeting, Bergen, Norway, 2006
`US-Co-organizer, Japan-US Workshop on Sustainable Chemical Synthesis, Honolulu, HI, 2005
`Co-organizer, Pacifichem 2005, Symposium on Green Chemistry, Honolulu, HI, 2005
`Co-organizer, Pacifichem 2005, Symposium on Organic Free Radicals, Honolulu, HI, 2005
`International Advisory Committee, ISoFT’05 (International Society of Fluorous Technologies),
`Bordeaux, France, 2005
`Organizer of Symposium on “Recent Advances in Fluorous Chemistry”, ACS Meeting, Washington,
`D.C., 2005
`Advisory Committee, 9th International Symposium for Organic for Free Radicals, Corsica, France, 2004
`Euchem Meeting on Free Radicals, International Advisory Board, 2002
`Co-organizer, ACS Meeting, Symposium on Combinatorial Synthesis of Natural Products, 2002
`Co-organizer, Organic Radical Chemistry Symposium, Pacifichem, 2000
`International Organizing Committee, “Gomberg 2000: A Century of Radical Chemistry”, 2000
`Free Radical Gordon Conference: vice chair, 1997; chair, 1999
`Organizer, NSF Synthetic Workshop, 1994-1997
`
`Scientific Consulting
`Fluorous Technologies, Inc., Founder and Chief Scientific Advisor, 2000-2012
`Consultant, Arno Therapeutics, 2007-2011
`Member, University of Pittsburgh Center for Methodology and Library Development (UPCMLD) Board,
`2003-2014
`Scientific Advisory Board, NeoGenesis, Inc., Boston, MA, 1997-2000
`Consultant, Bayer, Inc., 1994-2004
`Consultant, Wyeth-Ayerst Pharmaceuticals, 1986-1999
`Scientific Advisory Board, CombiChem, Inc., LaJolla, CA, 1997-1999
`Consultant, Parke-Davis, 1996-1997
`Consultant, Cubist, Inc., 1994-1995
`Consultant, FMC, Inc., 1992-1996
`Consultant, Lederle Laboratories, 1988-1990
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`PAGE -3-
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`Curriculum Vitae
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`D. P. Curran
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`Volunteer Organizations
`AAAS Annual Scientific Meeting Program Committee, 2016–2018
`Council Delegate, Chemistry, Amer. Assoc. for the Advancement of Science (AAAS), 2004-2007
`Advisory Board, International Society of Heterocyclic Chemistry, 2002-2004
`Chair, ACS Division of Organic Chemistry Graduate Fellowship Program, 1999-2004
`ACS Division of Organic Chemistry, Past Chair, 2001, Chair, 2000, Chair-Elect, 1999, Alternate
`Councilor, 1992-1994, Executive Committee Member, 1990-1992
`Advisory Board, International Society for Heterocyclic Chemistry, 1998-1999
`
`Editorial Positions
`Co-editor (w J. Gladysz), Tetrahedron “Symposium in Print” on Fluorous Chemistry, 2002
`Associate Editor, Organic Syntheses, 1998-2006
`American Co-Editor, Tetrahedron Lett., 1998-2001, American Associate Editor, Tetrahedron:
`Asymmetry, 1993-2001 and Tetrahedron Lett., 1995-1997
`Associate Editor, Organic Reactions, 1991-2001
`Editor, Advances in Cycloaddition, JAI Press, 1987-1993
`
`Other
`ACS Minicourse on Chemical Discovery, Organizer and Presenter, 2000-2003
`Invited Expert Analyst, Chemtracts: Organic Chemistry, 1993-2000
`NIH Study Sections, various years
`ACS National Historic Chemical Landmark for “The Discovery of Organic Free Radicals by Moses
`Gomberg”, Presented to the University of Michigan on the Gomberg centenial in 2000; co-
`nominator and member of the Historical Site Committee
`American Cancer Society Study Section, 1993-1996
`Contributor to “Articles Alert” column of The Scientist, 1990-1991
`Member, American Chemical Society (ACS), American Association for the Advancement of Science
`(AAAS) Society for Heterocyclic Chemistry, Pittsburgh Cancer Center, University of Pittsburgh Drug
`Discovery Institute
`
`
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`
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`
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`PUBLICATIONS
`
`480. A. J. Clark, D. P. Curran, D. J. Fox, F. Ghelfi, C. S. Guy, B. Hay, N. James, J. M. Phillips, F.
`Roncaglia, P. B. Sellars, P. Wilson, H. Zhang, Axially Chiral Enamides: Substituent Effects,
`Rotation Barriers and Implications for Their Cyclization Reactions, J. Org. Chem. 2016, 81,
`5547-5565. 10.1021/acs.joc.6b00889
`479. D. P. Curran, T. R. McFadden, Understanding Initiation with Triethylboron and Oxygen: The
`Differences between Low-Oxygen and High-Oxygen Regimes, J. Am. Chem. Soc. 2016, 138,
`7741-7752. 10.1021/jacs.6b04014
`T. H. Allen, D. P. Curran, Relative Reactivity of Stable Ligated Boranes and a Borohydride Salt
`in Rhodium(II)-Catalyzed Boron–Hydrogen Insertion Reactions, J. Org. Chem. 2016, 81, 2094-
`2098. 10.1021/acs.joc.6b00091
`477. A. Studer, D. P. Curran, Catalysis of Radical Reactions: A Radical Chemistry Perspective,
`Angew. Chem. Int. Ed. 2016, 55, 58-102. 10.1002/anie.201505090
`476. S. Gardner, T. Kawamoto, D. P. Curran, 1,3-Dimethylimidazoyl-2-ylidene Borane, Org. Synth.
`2015, 92, 342-355. 10.15227/orgsyn.092.0342
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`478.
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`474.
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`473.
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`472.
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`471.
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`469.
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`468.
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`475. H. Zhang, E. B. Hay, S. J. Geib, D. P. Curran, Fates of Imine Intermediates in Radical
`Cyclizations of N-Sulfonylindoles and Ene-Sulfonamides, Beil. J. Org. Chem. 2015, 11, 1649-
`1655. 10.3762/bjoc.11.181
`S. Gardner, T. Kawamoto, D. P. Curran, Synthesis of 1,3-Dialkylimidazol-2-ylidene Boranes
`from 1,3-Dialkylimidazolium Iodides and Sodium Borohydride, J. Org. Chem. 2015, 80, 9794-
`9797. 10.1021/acs.joc.5b01682
`S. Nerkar, D. P. Curran, Synthesis and Suzuki Reactions of N-Heterocyclic Carbene
`Difluoro(aryl)boranes, Org. Lett. 2015, 17, 3394-3397. 10.1021/acs.orglett.5b01101
`T. Watanabe, D. P. Curran, T. Taniguchi, Hydroboration of Arynes Formed by Hexadehydro-
`Diels–Alder Cyclizations with N-Heterocyclic Carbene Boranes, Org. Lett. 2015, 17, 3450-3453.
`10.1021/acs.orglett.5b01480
`T. Kawamoto, S. J. Geib, D. P. Curran, Radical Reactions of N-Heterocyclic Carbene Boranes
`with Organic Nitriles: Cyanation of NHC-Boranes and Reductive Decyanation of Malononitriles,
`J. Am. Chem. Soc. 2015, 137, 8617-8622. 10.1021/jacs.5b04677
`470. K. Damodaran, X. Li, X. Pan, D. P. Curran, Dynamic Behavior of N-Heterocyclic Carbene
`Boranes: Boron–Carbene Bonds in B,B-Disubstituted N,N-Dimethylimidazol-2-ylidene Boranes
`Have Substantial Rotation Barriers, J. Org. Chem. 2015, 80, 4465-4469. 10.1021/acs.joc.5b00324
`E. B. Hay, H. Zhang, D. P. Curran, Rearrangement Reactions of 1,1-Divinyl-2-phenylcyclo-
`propanes, J. Am. Chem. Soc. 2015, 137, 322-327. 10.1021/ja510608u
`T. Taniguchi, D. P. Curran, Hydroboration of Arynes with N-Heterocyclic Carbene Boranes,
`Angew. Chem. Int. Ed. 2014, 53, 13150-13154. 10.1002/anie.201408345
`467. N. Basar, K. Damodaran, H. Liu, G. A. Morris, H. M. Sirat, E. J. Thomas, D. P. Curran,
`Systematic Comparison of Sets of 13C NMR Spectra That Are Potentially Identical. Confirmation
`of the Configuration of a Cuticular Hydrocarbon from the Cane Beetle Antitrogus Parvulus, J,
`Org. Chem. 2014, 16, 7477-7490. 10.1021/jo5012027
`466. A. Studer and D. P. Curran, The Electron is a Catalyst, Nature Chem. 2014, 6, 765-773.
`10.1038/nchem.2031
`465. X. Pan, D. P. Curran, Neutral Sulfur Nucleophiles: Synthesis of Thioethers and Thioesters by
`Substitution Reactions of N-Heterocyclic Carbene Boryl Sulfides and Thioamides. Org. Lett.
`2014, 16, 2738-21. 10.1021/ol5010164
`464. H. Zhang, K. O. Jeon, E. B. Hay, S. J. Geib, D. P. Curran, M. G. LaPorte, Radical [3 + 2]-
`Annulation of Divinylcyclopropanes: Rapid Synthesis of Complex Meloscine Analogs, Org. Lett.
`2014, 16, 94-97. 10.1021/ol403078e
`463. C. R. J. Stephenson, A. Studer, D. P. Curran, The Renaissance of Organic Radical Chemistry –
`Deja Vu All over Again, Beil. J. Org. Chem. 2013, 9, 2778-2780. 10.3762/bjoc.9.312
`462. X. Pan, J. Lalevée, E. Lacôte, D. P. Curran, Disulfides and Boryl Sulfides Serve as Both Initiators
`and Precatalysts in Radical Reductions of Halides by an N-Heterocyclic Carbene⋅Borane, Adv.
`Synth. Catal. 2013, 355, 3522-3526. 10.1002/adsc.201300752
`461. A. Dewanji, S. Murarka, D. P. Curran, A. Studer, Phenyl Hydrazine as Initiator for Direct Arene
`C–H Arylation Via Base Promoted Homolytic Aromatic Substitution, Org. Lett. 2013, 15, 6102-
`6105. 10.1021/ol402995e
`460. A. Boussonnière, X. Pan, S. J. Geib, D. P. Curran, Borenium-Catalyzed Hydroborations of Silyl-
`Substituted Alkenes and Alkynes with a Readily Available N-Heterocyclic Carbene–Borane,
`Organometallics 2013, 32, 7545-7550. 10.1021/om400932g
`S. Telitel, A.-L. Vallet, S. Schweizer, B. Delpech, N. Blanchard, F. Morlet-Savary, B. Graff, D.
`P. Curran, M. Robert, E. Lacôte, J. Lalevée, Formation of N-Heterocyclic Carbene–Boryl
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`459.
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`Curriculum Vitae
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`D. P. Curran
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`Radicals through Electrochemical and Photochemical Cleavage of the B–S Bond in N-
`Heterocyclic Carbene–Boryl Sulfides, J. Am. Chem. Soc. 2013, 135, 16938-16947.
`10.1021/ja4066267
`458. H. Zhang, E. B. Hay, S. J. Geib, D. P. Curran, Radical Cyclizations of Cyclic Ene Sulfonamides
`Occur with β-Elimination of Sulfonyl Radicals to Form Polycyclic Imines, J. Am. Chem. Soc.
`2013, 135, 16610-16617. 10.1021/ja408387d
`457. A. Prokofjevs, J. W. Kampf, A. Solovyev, D. P. Curran, E. Vedejs, Weakly Stabilized Primary
`Borenium Cations and Their Dicationic Dimers, J. Am. Chem. Soc. 2013, 135, 15686-15689.
`10.1021/ja407458k
`456. X. Pan, A. Boussonnière, D. P. Curran, Molecular Iodine Initiates Hydroborations of Alkenes
`with N-Heterocyclic Carbene Boranes, J. Am. Chem. Soc. 2013 135, 14443-14447.
`10.1021/ja407678e
`455. X. Li, D. P. Curran, Insertion of Reactive Rhodium Carbenes into Boron–Hydrogen Bonds of
`Stable N-Heterocyclic Carbene Boranes, J. Am. Chem. Soc. 2013, 135, 12076-12081.
`10.1021/ja4056245
`454. X. Pan, A.-L. Vallet, S. Schweizer, K. Dahbi, B. Delpech, N. Blanchard, B. Graff, S. J. Geib, D.
`P. Curran, J. Lalevée, E. Lacôte, Mechanistic and Preparative Studies of Radical Chain
`Homolytic Substitution Reactions of N-Heterocyclic Carbene Boranes and Disulfides, J. Am.
`Chem. Soc. 2013, 135, 10484-10491. 10.1021/ja403627k
`453. M. Makhlouf Brahmi, M. Malacria, D. P. Curran, L. Fensterbank, E. Lacôte, Substituent Effects
`in NHC-Boranes: Reactivity Switch in the Nucleophilic Fluorination of NHC-Boranes, Synlett
`2013, 24, 1260-1262. 10.1055/s-0033-1338847
`J. Buter, E. A. Yeh, O. W. Budavich, K. Damodaran, A. J. Minnaard, D. P. Curran, Synthesis and
`Analysis of the All-(S) Side Chain of Phosphomycoketides: A Test of NMR Predictions for
`Saturated Oligoisoprenoid Stereoisomers, J. Org. Chem. 2013, 78, 4913-4918.
`10.1021/jo4005298
`J. Mandel, X. Pan, E. B. Hay, S. J. Geib, C. S. Wilcox, D. P. Curran, Rotational Isomers of N-
`Methyl-N-Arylacetamides and Their Derived Enolates: Implications for Asymmetric Hartwig
`Oxindole Cyclizations, J. Org. Chem. 2013, 78, 4083-4089. 10.1021/jo400385t
`450. D. Gatineau, Q. Zhao, D. P. Curran, M. Malacria, E. Lacote, L. Fensterbank, J.-P. Goddard, N-
`Heterocyclic Carbene-Initiated Hydrosilylation of Styryl Alcohols with Dihydrosilanes: A
`Mechanistic Investigation, Dalton Trans. 2013, 42, 7458-7462. 10.1039/C3DT32983F
`449. T. Kawamoto, T. Okada, D. P. Curran, I. Ryu, Efficient Hydroxymethylation Reactions of
`Iodoarenes Using CO and 1,3-Dimethylimidazol-2-ylidene Borane, Org. Lett. 2013, 15, 2144-
`2147. 10.1021/ol4006294
`448. V. Lamm, X. Pan, T. Taniguchi, D. P. Curran, Reductions of Aldehydes and Ketones with a
`Readily Available N-Heterocyclic Carbene Borane and Acetic Acid, Beilstein J. Org. Chem.
`2013, 9, 675-680. 10.3762/bjoc.9.76
`S. Zhu, A. Das, L. Bui, H. Zhou, D. P. Curran, M. Rueping, Oxygen Switch in Visible-Light
`Photoredox Catalysis: Radical Additions and Cyclizations and Unexpected C–C-Bond Cleavage
`Reactions, J. Am. Chem. Soc. 2013, 135, 1823-1829. 10.1021/ja309580a
`446. E. A.-H. Yeh, E. Kumli, K. Damodaran, D. P. Curran, Bare-Minimum Fluorous Mixture
`Synthesis of a Stereoisomer Library of 4,8,12-Trimethylnonadecanols and Predictions of Nmr
`Spectra of Saturated Oligoisoprenoid Stereoisomers, J. Am. Chem. Soc. 2013, 135, 1577-1584.
`10.1021/ja311606u
`445. A. Sasmal, T. Taniguchi, P. Wipf, D. P. Curran, Memory of Chirality in Rebound Cyclizations of
`α-Amide Radicals, Can. J. Chem. 2012, 91, 1-5. 10.1139/v2012-085
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`452.
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`451.
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`447.
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`440.
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`439.
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`438.
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`437.
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`444. A. Solovyev, E. Lacôte, D. P. Curran, Tetrahydrofuran Ring Opening and Related Reactions with
`an N-Heterocyclic Carbene-Boryl Trifluoromethanesulfonate, Dalton Trans. 2013, 42, 695-700.
`10.1039/c2dt31773g
`443. D. P. Curran, Free at Last!, Nat. Chem. 2012, 4, 958. 10.1038/nchem.1507
`442.
`T. Taniguchi, D. P. Curran, Silica Gel Promotes Reductions of Aldehydes and Ketones by N-
`heterocyclic Carbene Boranes, Org. Lett. 2012, 14, 4540-4543. 10.1021/ol302010f
`441. A. Prokofjevs, A. Boussonnière, L. Li, H. Bonin, E. Lacôte, D. P. Curran, E. Vedejs, E.,
`Borenium Ion Catalyzed Hydroboration of Alkenes with N-heterocyclic Carbene-Boranes, J. Am.
`Chem. Soc. 2012, 134, 12281-12288. 10.1021/ja305061c
`E. Lacôte, D. P. Curran, D. P., J. Lalevée, NHC-boranes: Air- and Water-tolerant Co-initiators for
`Type II Photopolymerizations, Chimia 2012, 66, 382-385. 10.2533/chimia.2012.382
`J. Lalevée, S. Telitel, M. A. Tehfe, J. P. Fouassier, D. P. Curran, E. Lacôte, N-Heterocyclic
`Carbene Boranes Accelerate Type I Radical Photopolymerizations and Overcome Oxygen
`Inhibition, Angew. Chem. Int. Ed. 2012, 51, 5958-5961. 10.1002/anie.201200975
`E. Merling, V. Lamm, S. J. Geib, E. Lacôte, D. P. Curran, [3+2]-Dipolar Cycloaddition Reactions
`of an N-Heterocyclic Carbene Boryl Azide, Org. Lett. 2012, 14, 2690-2693. 10.1021/ol300851m
`J. D. Moretti, X. Wang, D. P. Curran, Minimal Fluorous Tagging Strategy that Enables the
`Synthesis of the Complete Stereoisomer Library of SCH725674 Macrolactones, J. Am. Chem.
`Soc. 2012, 134, 7963-7970. org/10.1021/ja302260d
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`436. X. Pan, E. Lacôte, J. Lalevée, D. P. Curran, Polarity Reversal Catalysis in Radical Reductions of
`Halides by N-Heterocyclic Carbene Boranes, J. Am. Chem. Soc. 2012, 134, 5669−5674.
`10.1021/ja300416f
`435. D. P. Curran, A. Boussonnière, S. J. Geib, E. Lacôte, The Parent Borylene: Betwixt and Between,
`Angew. Chem. Int. Ed. 2012, 15, 1602-1605. 10.1002/anie.201107238
`434. Q. Zhao, D. P. Curran, M. Malacria, L. Fensterbank, J.-P. Goddard, E. Lacôte, NHC-Catalyzed
`Chemo- and Regioselective Hydrosilylation of Carbonyl Derivatives, Synlett, 2012, 23, 433-437.
`10.1055/s-0031-1290208
`433. D. P. Curran, M. K. Sinha, K. Zhang, J. J. Sabatini, D.-H. Cho, Binary Fluorous Tagging Enables
`the Synthesis and Separation of a 16-Stereoisomer Library of Macrosphelides, Nature Chemistry,
`2012, 4, 124-129. 10.1038/NCHEM.1233
`432. A. Solovyev, S. J. Geib, E. Lacôte, D. P. Curran, Reactions of Boron-Substituted N-Heterocyclic
`Carbene Boranes with Triflic Acid. Isolation of a New Dihydroxyborenium Cation,
`Organometallics, 2012, 31, 54-56. 10.1021/om201260b
`431. M. Horn, H. Mayr, E. Lacôte, E. Merling, J. Deaner, S. Wells, T. McFadden, D. P. Curran, N-
`Heterocyclic Carbene Boranes are Good Hydride Donors, Org. Lett. 2012, 14, 82-85.
`10.1021/ol202836p
`430. M.-A. Tehre, J. Monot, M. Malacria, L. Fensterbank, J.-P. Fouassier, D. P. Curran, E. Lacôte, J.
`Lalevée, A Water-Compatible NHC-Borane: Photopolymerizations in Water and Rate Constants
`for Elementary Radical Reactions, ACS Macro Lett. 2012, 1, 92-95. 10.1021/mz200087g
`429. R. Bajpai, D. P. Curran, Synthesis and Spectroscopic Analysis of a Stereoisomer Library of the
`Phytophthora Mating Hormone α1 and Derived Bis-Mosher Esters, J. Am. Chem. Soc. 2011, 133,
`20435-20443. 10.1021/ja2082679
`428. A. Solovyev, E. Lacôte, D. P. Curran, Ring Lithiation and Functionalization of Imidazol-2-
`ylidene-boranes, Org. Lett. 2011, 13, 6042-6045. 10.1021/ol202516c
`
`PAGE -7-
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`
`Curriculum Vitae
`
`
`
`D. P. Curran
`
`422.
`
`421.
`
`427. A. Bruch, R. Fröhlich, S. Grimme, A. Studer, D. P. Curran, The Product, Two Pathways: Initially
`Divergent Radical Reactions Reconverge to Form a Single Product in High Yield, J. Am. Chem.
`Soc. 2011, 133, 16270-16276. 10.1021/ja2070347
`
`426. D. P. Curran, A. Solovyev, M. Makhlouf Brahmi, L. Fensterbank, M. Malacria, E. Lacôte,
`Synthesis and Reactions of N-Heterocyclic Carbene Boranes, Angew. Chem. Int. Ed. 2011, 50,
`10294-10317. 10.1002/anie.201102717
`425. M. Jiménez, W. Zhu, A. Vogt, B. W. Day, D. P. Curran, Efficient Syntheses of 25,26-
`Dihydrodictyostatin and 25,26-Dihydro-6-epi-dictyostatin: Two Potent New Microtubule-
`Stabilizing Agents, Beilstein J. Org. Chem. 2011, 7, 1372-1378. 10.3762/bjoc.7.161
`424. Q. Zhao, D. P. Curran, M. Malacria, L. Fensterbank, J.-P. Goddard, E. Lacôte, N-Heterocyclic
`Carbene-Catalyzed Hydrosilylation of Styryl and Propargylic Alcohols with Dihydrosilanes,
`Chem. Eur. J. 2011, 17, 9911-9914. 10.1002/chem.201101822
`423. H. Zhang and D. P. Curran, A Short Total Synthesis of (±)-Epimeloscine and (±)-Meloscine
`Enabled by a Cascade Radical Annulation of a Divinylcyclopropane, J. Am. Chem. Soc. 2011,
`133, 10376-10378. 10.1021/ja2042854
`J. C. Walton, M. Makhlouf Brahmi, J. Monot, L. Fensterbank, M. Malacria, D. P. Curran, E.
`Lacôte, Electron Paramagnetic Resonance and Computational Studies of Radicals Derived from
`Boron-Substituted N-Heterocyclic Carbene Boranes, J. Am. Chem. Soc. 2011, 133, 10312-10321.
`10.1021/ja2038485
`L. L. Vollmer, M. Jiménez, D. P. Camarco, W. Zhu, H. N. Daghestani, R. Balachandran, C. E.
`Reese, J. S. Lazo, N. A. Hukriede, D. P. Curran, B. W. Day, A. Vogt, A Simplified Synthesis of
`Novel Dictyostatin Analogues with In Vitro Activity against Epothilone B-Resistant Cells and
`Antiangiogenic Activity in Zebrafish Embryos, Mol. Cancer Ther. 2011, 10, 994-1006.
`10.1158/1535-7163.MCT-10-1048
`420. A. J. Clark, D. P. Curran, J. V. Geden, N. James, P. Wilson, Bond Rotation Dynamics of
`Enamides: The Effect of the Acyl Group and Potential for Chirality Transfer during 5-Endo Trig
`Radical Cyclizations. J. Org. Chem. 2011, 76, 4546-4551. 10.1021/jo200343z
`419. A. Studer, D. P. Curran, Organocatalysis and C–H Activation Meet Radical- and Electron-
`Transfer Reactions, Angew. Chem. Int. Ed. 2011, 50, 5018-5022. 10.1002/anie.201101597
`S.-H. Ueng, L. Fensterbank, E. Lacôte, M. Malacria, and D. P. Curran, Radical Reductions of
`Alkyl Halides Bearing Electron Withdrawing Groups with N-heterocyclic Carbene Boranes, Org.
`Biomol. Chem. 2011, 9, 3415-3420. 10.1039/c0ob01075h
`417. V. Gudipati, D. P. Curran, Synthesis of C1-C20 and C21-C40 Fragments of Tetrafibricin,
`Tetrahedron Lett. 2011, 52, 2254-2257. 10.1016/j.tetlet.2011.01.086
`416. A. S. Jogalekar, K. Damodaran, F. H. Kriel, W.-H. Jung, A. A. Alcaraz, S. Zhong, D. P. Curran,
`J. P. Snyder, Dictyostatin Flexibility Bridges Conformations in Solution and in the β-Tubulin
`Taxane Binding Site. J. Am. Chem. Soc. 2011, 133, 2427-2436. 10.1021/ja1023817
`415. M.-A. Tehfe, J. Monot, M. Makhlouf Brahmi, H. Bonin-Dubarle, D. P. Curran, M. Malacria, L.
`Fensterbank, E. Lacôte, J. Lalevée, J.-P. Fouassier, N-Hetereocyclic Carbene-Borane Radicals as
`Efficient Initiating Species of Photopolymerization Reactions under Air, Polym. Chem. 2011, 2,
`625-631. 10.1039/c0py00296h
`414. D. B Guthrie, S. J. Geib, D. P. Curran, Radical and Heck Cyclizations of Diastereomeric o-
`Haloanilide Atropisomers, J. Am. Chem. Soc. 2010, 133, 115-122. 10.1021/ja108795x
`J. Monot, A. Solovyev, H. Bonin-Dubarle, É. Derat, D. P. Curran, M. Robert, L. Fensterbank, M.
`Malacria, E. Lacôte, Generation and Reactions of an Unsubstituted N-Heterocyclic Carbene
`Boryl Anion, Angew. Chem. Int. Ed. 2010, 49, 9166-9169. 10.1002/anie.201004215
`
`418.
`
`413.
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`PAGE -8-
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`Curriculum Vitae
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`
`D. P. Curran
`
`409.
`
`412. Y. Lu, S. J. Geib, K. Damodaran, B. Sui, Z. Zhang, D. P. Curran, W. Zhang, Fluorous
`Diasteromeric Mixture Synthesis (FDMS) of Hydantoin-fused Hexahydrochromeno[4,3-b]
`pyrroles. Chem. Comm. 2010, 46, 7578-7580. 10.1039/c0cc01967d
`411. M. Makhlouf Brahmi, J. Monot, M. Desage-El Murr, D. P. Curran, L. Fensterbank, E. Lacôte, M.
`Malacrai, Preparation of NHC Borane Complexes by Lewis Base Exchange with Amine- and
`Phosphine-Boranes, J. Org. Chem. 2010, 75, 6983- 6985. 10.1021/jo101301d
`410. A. Solovyev, Q. Chu, S. J. Geib, L. Fensterbank, M. Malacria, E. Lacôte, D. P. Curran,
`Substitution Reactions of Tetracoordinate Boron: Synthesis of N-Heterocyclic Carbene Boranes
`with Boron–Heteroatom Bonds, J. Am. Chem. Soc. 2010, 132, 15072-15080. 10.1021/ja107025y
`J. Monot, L. Fensterbank, M. Malacria, E. Lacôte, S. J. Geib, D. P. Curran, CAAC Boranes.
`Synthesis and Characterization of Cyclic (Alkyl) (Amino) Carbene Borane Complexes from BF3
`and BH3, Beilstein J. Org. Chem. 2010, 6, 709–712. 10.3762/bjoc.6.82
`408. D. C. Harrowven, D. P. Curran, S. L. Kostiuk, I. L. Wallis-Guy, S. Whiting, K. J. Stenning, B.
`Tang, E. Packard, L. Nanson, Potassium Carbonate-Silica: A Highly Effective Stationary Phase
`for the Chromatographic Removal of Organotin Impurities, Chem. Comm., 2010, 46, 6335-6337.
`10.1039/b000000x
`407. A. Bruch, A. Ambrosius, R. Fröhlich, A. Studer, D. B. Guthrie, H. Zhang, D. P. Curran, Memory
`of Axial Chirality in Aryl Radical Phosphanylations, J. Am. Chem. Soc. 2010, 132, 11452-11454.
`10.1021/ja105070k
`406. K. Nozaki, Y. Aramaki, M. Yamashita, S.-H. Ueng, M. Malacria, E. Lacôte, D. P. Curran,
`Boryltrihydroborate: Synthesis, Structure, and Reactivity as a Reductant in Ionic, Organometallic,
`and Radical Reactions, J. Am. Chem. Soc. 2010, 132. 11449-11451. 10.1021/ja105277u
`405. W. Zhu, M. Jiménez, W.-H. Jung, D. P. Camarco, R. Balachandran, A. Vogt, B. W. Day, D. P.
`Curran, Streamlined Syntheses of (–)-Dictyostatin, 16-Desmethyl-25,26-dihydrodictyostatin, and
`6-epi-16-Desmethyl-25,26-dihydrodictyostatin, J. Am. Chem. Soc. 2010, 132, 9175-9187.
`10.1021/ja103537u; PMCID: PMC2903049
`S.-H. Ueng, L. Fensterbank, E. Lacôte, M. Malacria, D. P. Curran, Radical Deoxygenation of
`Xanthates and Related Functional Groups with New Minimalist N-Heterocyclic Carbene
`Boranes. Org. Lett. 2010, 12, 3002-3005. 10.1021/ol101015m
`403. A. Solovyev, S.-H. Ueng, J. Monot, L. Fensterbank, M. Malacria, E. Lacôte, D. P. Curran,
`Estimated Rate Constants for Hydrogen Abstraction from N-Heterocyclic Carbene⎯Borane
`Complexes by an Alkyl Radical, Org. Lett. 2010, 12, 2998-3001. 10.1021/ol101014q
`402. B. Sui, E. A.-H. Yeh, D. P. Curran, Assignment of the Structure of Petrocortyne A by Mixture
`Synthesis of Four Candidate Stereoisomers, J. Org. Chem. 2010, 75, 2942-2954.
`10.1021/jo100115h; PMCID: PMC2871111
`401. M.-A. Tehfe, M. Makhlouf Brahmi, J.-P. Fouassier, D. P. Curran, M. Malacria, L. Fensterbank,
`E. Lacôte, J. Lalevée, N-Heterocyclic Carbenes–Borane Complexes: A New Class of Initiators
`for Radical Photopolymerization, Macromolecules 2010, 43, 2261-2267. 10.1021/ma902492q
`J. C. Walton, M. Makhlouf Brahmi, L. Festerbank, E. Lacôte, M. Malacria, Q. Chu, S.-H. Ueng,
`A. Solovyev, D. P. Curran, EPR Studies of the Generation, Structure, and Reactivity of N-
`Heterocyclic Carbene Borane Radicals, J. Am. Chem. Soc. 2010, 132, 2350-2358.
`10.1021/ja909502q
`399. K. Zhang, V. Gudpati, D. P. Curran, Fluorous Mixture Synthesis of Four Stereoisomers of the
`C21-C40 Fragment of Tetrafibricin, Synlett, 2010, 667-671. 10.1055/s-0029-1219376; PMCID:
`PMC2914344
`398. X. Li, D. P. Curran, Diverging Chemoselective Reactions of Separable Amide Rotational
`Isomers, Org. Lett. 2010, 12, 612-614. 10.1021/ol902808m
`
`404.
`
`400.
`
`PAGE -9-
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`Curriculum Vitae
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`D. P. Curran
`
`397.
`
`395.
`
`L. Wang, C. Cai, D. P. Curran, W. Zhang, Enantioselective α-Chlorination of Aldehydes with
`Recyclable Fluorous (S)-Pyrrolidine-Thiourea Bifunctional Organocatalyst, Synlett, 2010, No. 3,
`433-436. 10.1055/s-0029-1219198; PMCID: PMC2922060
`396. D. B. Guthrie, S. J. Geib, D. P. Curran, Synthesis of Highly Enantioenriched 3,4-
`Dihydroquinolin-2-ones by 6-Exo-trig Radical Cyclizations of Axially Chiral α-Halo-ortho-
`alkenyl Anilides, J. Am. Chem. Soc. 2009, 131, 15492-15500. 10.1021/ja9066282; NIHMS ID:
`150630; PMCID: PMC2784126
`J. Monot, M. Makhlouf Brahmi, S.-H. Ueng, C. Robert, M. Desage-El Murr, D. P. Curran, M.
`Malacria, L. Fensterbank, E. Lacôte, Suzuki–Miyaura Coupling of NHC–Boranes: A New
`Addition to the C–C Coupling Toolbox, Org. Lett. 2009, 11, 4914-4917. 10.1021/ol902012c
`394. K. Damodaran, S. D. Nielsen, S. J. Geib, W. Zhang, Y. Lu, D. P. Curran, Aryl–Csp3 Bond
`Rotation Barriers of 2-Aryl Perhydropyrrolo[3,4-c]pyrrole-1,3-diones, J. Org. Chem. 2009, 74,
`5481-5485. 10.1021/jo901123c
`393. A. L. Mandel, V. Bellosta, D. P. Curran, J. Cossy, A Versatile Route to the Tulearin Class of
`Macrolactones: Synthesis of a Stereoisomer of Tulearin A, Org. Lett. 2009, 11, 3282-3285.
`10.1021/ol900936t; NIHMS ID: 128190; PMCID: PMC2736336
`S.-H. Ueng, A. Solovyev, X. Yuan, S. J. Geib, L. Fensterbank, E. Lacôte, M. Malacria, M.
`Newcomb, J. C. Walton, D. P. Curran, N-Heterocyclic Carbene Boryl Radicals: A New Class of
`Boron-Centered Radical, J. Am. Chem. Soc. 2009, 131, 11256-11262. 10.1021/ja904103x
`S. Werner, S. D. Nielsen, P. Wipf, D. M. Turner, P. G. Chambers, S. J. Geib, D. P. Curran, W.
`Zhang, Fluorous Parallel Synthesis of a Piperazinedione-Fused Tricyclic Compound Library, J.
`Comb. Chem. 2009, 11, 452-459. 10.1021/cc900003q; PMCID: PMC2921976
`390. Q. Chu, M. Makhlouf Brahmi, A. Solovyev, S.-H. Ueng, D. P. Curran, M. Malacria, L.
`Fensterbank, E. Lacôte, Ionic and Organometallic Reductions with N-Heterocyclic Carbene
`Boranes, Chem. Eur. J. 2009, 15, 12937-12940. 10.1002/chem.200902450
`389. V. Gudipati, R. Bajpai, D. P. Curran, Sulfanylation of 1,3-Dithiane Anions by 5-(Alkylsulfanyl)-
`1-Phenyltertrazoles, Collect. Czech. Chem. Commun. 2009, 74, 771-783. 10.1135/cccc2008195;
`PMCID: PMC2907546
`388. D. B. Guthrie, K. Damodaran, D. P. Curran, P. Wilson, A. J. Clark, Bond Rotation Dynamics of
`N-Cycloalkenyl-N-benzyl α-Haloacetamide Derivatives, J. Org. Chem. 2009, 74, 4262-4266.
`10.1021/jo900491w
`387. A. G. Sancho, X. Wang, B. Sui, D. P. Curran, Comparison of the Relative Reactivities of the
`Triisopropylsilyl Group With Two Fluorous Analogs, Adv. Synth. Catal. 2009, 351, 1035-1040.
`10.1002/adsc.200900061; PMCID: PMC2772155
`386. D. P. Curran and B. Sui, A “Shortcut” Mosher Ester Method to Assign Configurations of
`Stereocenters in Nearly Symmetric Environments, Fluorous Mixture Synthesis and Structure
`Assignment of Petrocortyne A, J. Am. Chem. Soc. 2009, 131, 5411-5413.
`10.1021/ja900849f; PMCID: PMC2891898
`
`F. Zhang, W. Zhang, Y. Zhang, D. P. Curran, G. Liu, Synthesis and Applications of a Light-
`385.
`Fluorous Glycosyl Donor, J. Org. Chem. 2009, 74, 2594-2597.
`10.1021/jo9000993; PMCID: PMC275420