12/5/2016
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`Rysurg - BlephEx® Home
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`Rysurg - BlephEx® Home
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`BlephEx® ... The First and Only Doctor Treatment for Dry Eye and
`Blepharitis
`
`Over 50% of all patients suffer from some type of dry eye and blepharitis symptoms.
`BlephEx® is a new, in-office procedure that allows your doctor to take an active role in treating dry
`eye and blepharitis.
`BlephEx® removes excess bacteria, biofilm and bacterial toxins, the main causes of inflammatory dry
`eye and lid disease.
`With regular treatments, patients finally enjoy a life free from the chronic and irritating symptoms
`associated with dry eye and blepharitis.
`The BlephEx® treatment is well tolerated and only takes a few minutes to perform.
`BlephEx® can save the patient hundreds of dollars in the costs of prescription drops and artificial
`tears.
`See your eye doctor for this latest breakthrough in eyecare technology and dry eye treatment.
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`http://www.rysurg.com/patients/
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`1/5
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`Blephex EX2016, p. 1
`MiBo v. Blephex, Case IPR 2016-01670
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`

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`Rysurg - BlephEx® Home
`12/5/2016
`I have several autoimmune diseases and suffer from dry, uncomfortable eyes. I was so excited when my
`husband, Dr. Thomas C. McIntosh told me he was adding the BlephEx treatment as a service to our
`patients. He and my daughter completed the training in Raleigh, NC and I looked forward with anticipation
`to receiving my first treatment.
`
`I was not disappointed! On the day of my first treatment, I was a bit anxious. All of my anxiety was
`completely eased, as the procedure was comfortable and to my surprise, quite relaxing! I compare it to a
`"spa procedure". As soon as my right eye was complete, I immediately noticed how "dirty" my left eye felt
`and could hardly wait for the treatment on the left eye to begin. After the treatment was completed, my
`eyes felt so fresh and clean. The BlephEx will certainly be a regular procedure for me every few months.
`
`- Carolina Vision Care
`Melonie Macintosh
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`Patient experience:
`"As an Eye Care Professional I did not know exactly what was causing my dry eyes. I did not have visable
`blepharitis and my glands did not look clogged, so when I had the BlephEx treatment and my eyelids
`expressed, I did not expect any big improvements, but my TBUT went from 4 seconds to 12 seconds in a
`2 week period."
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`Practice experience
`"Our office has had tremendous success combining the Oculus K5N, Eye Eco dry eye masks, and the
`BlephEx treatment. We feel the combination of treatments has elevated our dry eye level of care to new
`heights."
`
`- Kevin Whaley, LDO
`Practice Administrator The Eye Doctors
`
`“I was the first volunteer that you demonstrated the procedure on last night. The next morning my eyes
`were a little irritated when I stopped by the booth and bought the kit. By that evening my eyes were
`better. This morning and all day today my lids were not red, I actually felt moisture in my eyes when I
`woke up, and my conjunctivae were white. This is amazing! For the first time in decades my eyes look
`and feel good! I have not had to use a lubricating drop all day, and I usually use them every day. I was
`doing the Bruder mask every night with massage afterwards. I did not do lid scrubs much because they
`never seemed to work. I was about ready to go on Restasis, but have been delaying because of the cost.
`I also have used steroids and gotten short term relief. Punctal plugs also helped, but I could feel them, so
`had them removed. Finally I have found something that addresses the root of the problem and actually
`works! This is going to revolutionize my patient care. Thank you.”
`
`- Michael Moorehead, O.D.
`Hamilton Eyecare Center
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`http://www.rysurg.com/patients/
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`2/5
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`Blephex EX2016, p. 2
`MiBo v. Blephex, Case IPR 2016-01670
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`

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`Rysurg - BlephEx® Home
`12/5/2016
`“After 100 procedures performed, I can tell you the wonderful results in killing Mites. BlephEx is an
`amazing product for managing patients with ocular surface disease. Not only does it clean the palpebral
`margin, but it also massages the MB glands. I really love BlephEx, as does my patients.”
`
`- Sarah Veronica Benchimol, Benchimol Eye Clinic, Rio De Janeiro, Brazil
`
`“We have now had the BlephEx unit for about a month. In order to implement BlephEx into our office we
`did several steps. The first step was we dedicated a staff meeting to go over the reasons we are now
`doing BlephEx and how it was going to help our patients. Dr. Picken did the procedure on myself so the
`staff could watch. This allowed them to help understand how the procedure worked. We then put videos
`in each exam room that we obtained from your website. When a patient comes in for an exam and has
`any dry eye complaints the technician has them fill out the SPEED dry eye questionnaire and they are
`shown the video before the doctor sees them. If it is found during the exam that they are good
`candidates, we take pictures of their meibomian glands and blepharitis on their lids using the
`keratograph 5M. This helps the patient understand what is going on. After showing the pictures, doing
`the questionnaire and being told about the new procedure we have had very little resistance in going
`forward with the treatment. In three weeks we have done 15 procedures and patients coming back have
`been very pleased. We have started some on Cliradex at two weeks and explain at the procedure this is
`necessary if Demodex is the cause. The patients coming back being very pleased has made the entire
`office buy into the procedure. Thank you for giving us this new weapon to treat dry eyes.”
`
`- Bill Welder, OD
`
`“I am excited to get started with BlephEx. I did a treatment on my husband, who has been blessed with
`horrible Bleph/MGD, and he did it on me. (He is an MD). Then I offered it for free to two of my worst
`patients. People love to hear about my husbands treatment, and the I am seeing the first of my other two
`patients next week. I take pictures using a digital AS camera and also documented my husbands
`treatment using digital stills. Plan to use these images on our Facebook and page and website, as well as
`an article for Optometry Times.”
`
`- Tracy Swartz, OD
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`“BlephEx has fundamentally changed the way we practice. Its become an essential element for managing
`blepharitis and I use it routinely for debridement of the lids prior to manual expression or LipiFlow for
`MGD. It has definitely improved outcomes and makes a tremendous difference in patient comfort. I could
`not practice without it.”
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`- Art Epstein, OD
`
`“I have been using BlephEx for only a few months also and am really happy with it. I tried it out on my
`staff first and they gave me lots of great feedback regarding comfort and I was able to use this
`information with patients. I did the treatment on one lady recently and a few hours later she called from
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`http://www.rysurg.com/patients/
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`3/5
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`Blephex EX2016, p. 3
`MiBo v. Blephex, Case IPR 2016-01670
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`

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`Rysurg - BlephEx® Home
`12/5/2016
`the car elated, saying that "her eyes felt the best they had in months and her vision had already
`improved". I was surprised by that rapid improvement but very pleased that the treatment worked so fast
`for her.”
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`- Bridget A. Sundell, MD
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`“My practice acquired the BlephEx in January 2015. I used my mother as a "test" patient prior to
`purchasing the unit. She has grade 3-4 blepharitis. My mother felt immediately better after the
`procedure. After trying countless tear formulations, Restasis, and lid scrubs, nothing really worked to
`help her dryness and blepharitis. BlephEx has been truly helpful for her and it was worth the purchase if
`not only to just help my mother! To encourage sales in my office, I sent a mailing out to my blepharitis
`and dry eye patients. Within the first week of the mailing, calls were coming in to book the procedure. So
`far, I am very happy with my purchase of BlephEx!”
`
`- Alexandra Kostick, MD
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`“I really like everything about this procedure, I believe that I can finally have some effect on a nagging
`problem that is a root cause of many aspects of external ocular disease. It's certainly not glamorous but it
`gets down into the trench and begins the heavy lifting. Thanks for starting a new procedure that we
`should have had at least 35 yrs ago.”
`
`- Lewis Kizer O.D.
`
`"We have had our Blephex system for about 2 months. Before the system arrived, I had made a list of
`potential patients that would benefit from the treatment. As soon as it arrived my OD student intern and I
`reviewed the instructional materials/videos and started booking. We have treated over 20 patients in the
`last month. 19 out of the 20 have noted significant improvement of symptoms (you can’t please
`everyone). Many are looking forward to the next treatment! An added bonus is that my intern has a new
`technique for treating MGD and blepharitis"
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`- Bruce Lidkea, OD
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`"We are loving our Blephex. It was a little slow to get started, so I offered free treatments to 3 of my worst
`dry eye and blepharitis patients. That's all it took. We now have a real buzz going. The staff is
`enthusiastic, and patients are bringing in their family members and friends. A few people are already
`scheduling their next treatments several months out."
`
`- Julie S. Lee, MD
`
`President, Kentucky Academy of Eye Physicians and Surgeons
`“I have found great success with the use of the BlephEx device not only for anterior blepharitis cleaning
`and treatment in cases of staphylococcal and demodex blepharitis, but also to remove biofilms from the
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`http://www.rysurg.com/patients/
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`4/5
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`Blephex EX2016, p. 4
`MiBo v. Blephex, Case IPR 2016-01670
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`

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`Rysurg - BlephEx® Home
`12/5/2016
`lower eyelid margin in patients with MGD. The clinical effectiveness and response from patients has been
`remarkable”
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`- Paul Karpecki, OD
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`http://www.rysurg.com/patients/
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`5/5
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`Blephex EX2016, p. 5
`MiBo v. Blephex, Case IPR 2016-01670