I lllll llllllll Ill lllll lllll lllll lllll lllll 111111111111111111111111111111111
`US009055953B2
`
`c12) United States Patent
`Lang et al.
`
`(10) Patent No.:
`(45) Date of Patent:
`
`US 9,055,953 B2
`*Jun. 16, 2015
`
`(75)
`
`(54) METHODS AND COMPOSITIONS FOR
`ARTICULAR REPAIR
`Inventors: Philipp Lang, Lexington, MA (US);
`Daniel Steines, Lexington, MA (US)
`(73) Assignee: ConforMIS, Inc., Bedford, MA (US)
`( * ) Notice:
`Subject to any disclaimer, the term ofthis
`patent is extended or adjusted under 35
`U.S.C. 154(b) by 300 days.
`
`This patent is subject to a terminal dis(cid:173)
`claimer.
`(21) Appl. No.: 121777,809
`May 11, 2010
`(22) Filed:
`Prior Publication Data
`(65)
`
`US 2010/0303313 Al
`
`Dec. 2, 2010
`
`Related U.S. Application Data
`
`(63) Continuation of application No. 12/317,472, filed on
`Dec. 22, 2008, which is a continuation of application
`
`(51)
`
`Int. Cl.
`G06K9/00
`G06F 17150
`
`(Continued)
`
`(2006.01)
`(2006.01)
`
`(Continued)
`
`(52) U.S. Cl.
`CPC ............. A61B 1711662 (2013.01); YJOT 29149
`(2015.01);
`
`(Continued)
`( 58) Field of Classification Search
`CPC . A61F 2/389; A61F 2/30756; A61F 2/30942;
`A61F 2/30767; A61F 2/3859; A61F
`2002/30062; A61F 2002/30677; A61F
`2002/30787; A61F 2002/30948; A61F
`2002/30957; A61F 2002/3097; A61F
`2002/4631; A61F 2310/00011; A61F
`2310/00023; A61F 2310/00029; A61F
`2310/00047; A61F 2310/00065; A61F
`2310/00071; A61F 2310/00077; A61F
`
`2310/00083; A61F 2310/00107; A61F
`2310/00113; A61F 2310/00119; A61F
`2310/00131; A61F 2310/00149; A61F
`2310/00155; A61F 2310/00293; A61F
`2310/00383; A61F 2310/00395; A61F
`2310/00592; G06F 17/50; A61B 5/4504;
`A61B 5/4528; A61B 17/8805; A61B 5/4514
`USPC ....... 606/102, 86 R, 79-85, 86 A, 96, 87-89;
`623/16.11, 18.11, 20.14, 20.21, 20.35,
`623/23.61, 914, 916; 705/2-3; 703/1-2;
`600/407,410,427,587;382/128
`See application file for complete search history.
`References Cited
`
`U.S. PATENT DOCUMENTS
`
`3,314,420 A
`3,605,123 A
`
`128/92
`4/1967 Smith et al.
`9/1971 Halm .................................... 3/1
`(Continued)
`
`FOREIGN PATENT DOCUMENTS
`
`1111987
`86209787
`2/1999
`2305966
`(Continued)
`OTHER PUBLICATIONS
`
`................ A61F 2/38
`................ A61F 2/28
`
`(56)
`
`CN
`CN
`
`Adam et al., "NMR tomography of the cartilage structures of the knee
`joint with 3-D volume image combined with a rapid optical-imaging
`computer," ROFO Fortschr. Geb. Rontgenstr. Nuklearmed., 150(1):
`44-48 (1989) Abstract Only.
`(Continued)
`
`Primary Examiner - Pedro Philogene
`(74) Attorney, Agent, or Firm - Sunstein Kann Murphy &
`Timbers LLP
`ABSTRACT
`(57)
`Disclosed herein are methods and compositions for produc(cid:173)
`ing articular repair materials and for repairing an articular
`surface. In particular, methods for providing articular repair
`systems. Also provided are articular surface repair systems
`designed to replace a selected area cartilage, for example, and
`surgical tools for repairing articular surfaces.
`61 Claims, 18 Drawing Sheets
`
`Measure size of area of diseased
`cartilage or cartilage loss
`
`Measure thickness of
`adjacent cartilage
`
`Measure curvature of articular
`surface andlor subchondral bone
`
`Select best fitting
`implant in library
`
`Generate custom implant
`patient specific
`
`Prepare implantation site
`
`Perform implantation
`
`-1-
`
`Smith & Nephew Ex. 1001
`IPR Petition - USP 9,055,953
`
`

`
`US 9,055,953 B2
`Page 2
`
`Related U.S. Application Data
`
`No. 10/305,652, filed on Nov. 27, 2002, now Pat. No.
`7,468,075, which is a continuation-in-part of applica-
`tion No. 10/160,667, filed on May 28, 2002.
`
`(60) Provisional application No. 60/293,488, filed on May
`25, 2001, provisional application No. 60/363,527,
`filed on Mar. 12, 2002, provisional application No.
`60/380,695, filed on May 14, 2002, provisional appli-
`cation No. 60/380,692, filed on May 14, 2002.
`
`(51)
`
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`
`Int. Cl.
`A61B 17116
`A61F 2130
`A61B 5100
`A61B 17188
`A61F 2138
`A61F 2146
`(52) U.S. Cl.
`CPC ............. A61B 514504 (2013.01); A61B 514514
`(2013.01); A61B 514528 (2013.01); A61B
`1718805 (2013.01); A61F 2130756 (2013.01);
`A61F 2130767 (2013.01); A61F 2130942
`(2013.01); A61F 213859 (2013.01); A61F
`2002130062 (2013.01); A61F 2002130677
`(2013.01); A61F 2002130787 (2013.01); A61F
`2002130948 (2013.01); A61F 2002130957
`(2013.01); A61F 200213097 (2013.01); A61F
`200214631 (2013.01); A61F 221010004
`(2013.01); A61F 2310100011 (2013.01); A61F
`2310100017 (2013.01); A61F 2310100023
`(2013.01); A61F 2310100029 (2013.01); A61F
`2310100047 (2013.01); A61F 2310100065
`(2013.01); A61F 2310100071 (2013.01); A61F
`2310100077 (2013.01); A61F 2310100083
`(2013.01); A61F 2310100107 (2013.01); A61F
`2310100113 (2013.01); A61F 2310100119
`(2013.01); A61F 2310100131 (2013.01); A61F
`2310100149 (2013.01); A61F 2310100155
`(2013.01); A61F 2310100293 (2013.01); A61F
`2310100383 (2013.01); A61F 2310100395
`(2013.01); A61F 2310100592 (2013.01); G06F
`17150 (2013.01); A61F 21389 (2013.01)
`
`(56)
`
`References Cited
`
`U.S. PATENT DOCUMENTS
`
`3,694,820 A
`3,798,679 A
`3,808,606 A
`3,816,855 A
`3,843,975 A
`3,852,830 A
`3,855,638 A
`3,938,198 A
`3,982,281 A
`3,987,499 A
`3,991,425 A
`4,052,753 A
`4,055,862 A
`4,085,466 A
`4,098,626 A
`4,164,793 A
`4,178,641 A
`4,203,444 A
`4,207,627 A
`4,211,228 A
`4,213,816 A
`4,219,893 A
`
`10/1972 Scales et al. .......................... 3/1
`3/1974 Ewald ................................... ~l
`5/1974 Tronzo .................................. ~l
`6/1974 Saleh .................................... ~l
`10/1974 Tronzo .................................. ~l
`12/1974 Marmor ................................ 3/1
`12/1974 Pilliar ................................... ~l
`2/1976 Kahnet al. ..................... 3/1.912
`9/1976 Giliberty ........................ 3/1.913
`10/1976 Scharbach et al. ............... 3/1.91
`1111976 Martin et al.
`.................... 3/1.91
`10/1977 Dedo .................................... ~l
`1111977 Farling ............................. 3/1.91
`4/1978 Goodfellow et al. ............ 3/1.91
`7/1978 Graham et al.
`149/19.4
`8/1979 Swanson .......................... 3/1.91
`12/1979 Grundei et al. ................ 3/1.911
`5/1980 Bonnell et al.
`128/276
`6/1980 Cloutier ......................... 3/1.911
`7/1980 Cloutier .
`128/303 R
`7/1980 Morris .
`156/245
`9/1980 Noiles ............................ 3/1.911
`
`7/1981 Swanson .......................... 3/1.91
`4,280,231 A
`111982 Buechel et al. ................ 3/1.911
`4,309,778 A
`7/1982 Buechel et al. .. .............. 3/1.911
`4,340,978 A
`8/1982 Kenny ........................... 3/1.911
`4,344,193 A
`111983 Weissman ....................... 433/36
`4,368,040 A
`3/1984 White .. ......................... 264/138
`4,436,684 A
`7/1984 McKay et al.
`128/303 R
`4,459,985 A
`2/1985 McDaniel .
`4,501,266 A
`128/69
`3/1985 Wall ................................. 3/1.91
`4,502,161 A
`3/1986 Moermann et al. .. ......... 364/474
`4,575,805 A
`5/1986 Keller .
`128/92 E
`4,586,496 A
`6/1986 Chapin et al. ................. 524/144
`4,594,380 A
`7/1986 Effron et al.
`4,601,290 A
`128/305
`9/1986 Caplan et al. ................... 424/95
`4,609,551 A
`12/1986 Campbell et al. ............... 623/16
`4,627,853 A
`4/1987 Gracovetsky .
`4,655,227 A
`128/781
`5/1987 Zichner et al. .................. 623/20
`4,662,889 A
`10/1987 Gracovetsky .
`4,699,156 A
`128/781
`12/1987 Averill et al. ................... 623/20
`4,714,472 A
`12/1987 Brooks, Jr. et al. ............. 623/20
`4,714,474 A
`12/1987 Amstutz et al. ................. 623122
`4,715,860 A
`111988 Kaufman et al.
`4,721,104 A
`128/92
`128/92 vw
`7/1988 Dunn eta!.
`4,759,350 A
`9/1988 Wevers ........................... 623/20
`4,769,040 A
`3/1989 Au.
`4,813,436 A
`128/779
`4/1989 Walker et al. ................... 623/20
`4,822,365 A
`4/1989 Russell et al.
`4,823,807 A
`128/773
`6/1989 Woolson .
`4,841,975 A
`128/653
`7/1989 Grande ........................... 623/11
`4,846,835 A
`9/1989 Witzel et al. .................... 623/20
`4,865,607 A
`10/1989 Alex son ..................... 128/92 VJ
`4,872,452 A
`1111989 Stone .............................. 623/18
`4,880,429 A
`1111989 Bloebaum et al. .................. 3/20
`4,883,488 A
`12/1989 Scott ............................. 269/328
`4,886,258 A
`12/1989 Forte et al. ...................... 623/20
`4,888,021 A
`6/1990 Fabian et al.
`4,936,853 A
`................... 623/20
`6/1990 Walker et al. ................... 623/23
`4,936,862 A
`7/1990 Martinez et al. ................ 623/20
`4,944,757 A
`12/1990 Matsen, III et al.
`4,979,949 A
`............ 606/53
`3/1991 Poggie et al. ................... 606/88
`5,002,547 A
`4/1991 Woolson ......................... 623/23
`5,007,936 A
`5/1991 Van Zile et al. ................. 623/20
`5,019,103 A
`6/1991 Wevers et al.
`5,021,061 A
`.................. 623/20
`8/1991 Vacanti et al. .................. 623/16
`5,041,138 A
`9/1991 Lawes ............................. 623/20
`5,047,057 A
`10/1991 Hofmann et al. ............... 606/87
`5,053,039 A
`10/1991 Winters .......................... 623/20
`5,059,216 A
`1111991 Richmond et al. .............. 623/18
`5,067,964 A
`3/1992 Bell
`5,099,859 A
`128/781
`4/1992 Fallin .............................. 623/23
`5,108,452 A
`6/1992 Bert et al.
`5,122,144 A
`....................... 606/88
`6/1992 Duncan et al. .................. 623/20
`5,123,927 A
`7/1992 Peterson ......................... 606/88
`5,129,908 A
`7/1992 Turner ............................ 623/20
`5,133,759 A
`9/1992 Berchem et al. ......... 364/474.24
`5,150,304 A
`10/1992 Shah .
`5,154,178 A
`128/653.2
`10/1992 Matsen, III et al.
`5,154,717 A
`............ 606/53
`1111992 Rhee et al. ................... 525/54.1
`5,162,430 A
`12/1992 Kenny ............................ 623/18
`5,171,322 A
`3/1993 Caplan et al. ................... 623/16
`5,197,985 A
`4/1993 Hunziker ...................... 424/423
`5,206,023 A
`7/1993 Caplan et al. ................... 623/16
`5,226,914 A
`8/1993 Bert et al.
`5,234,433 A
`....................... 606/88
`9/1993 Mugler, III et al. ........... 324/309
`5,245,282 A
`9/1993 Frank et al.
`5,246,013 A
`128/774
`9/1993 Bugle et al.
`5,246,530 A
`156/643
`10/1993 Poggie et al. ................... 606179
`5,250,050 A
`1111993 Bertin ............................. 623/20
`5,258,032 A
`12/1993 Hunziker ........................ 514/12
`5,270,300 A
`12/1993 Reuben .................... 364/474.24
`5,274,565 A
`2/1994 Bahler ............................ 623/20
`5,282,868 A
`2/1994 Khalil et al. .................. 524/872
`5,288,797 A
`3/1994 Glassman et al.
`5,299,288 A
`.............. 395/80
`4/1994 Mattson et al. .......... 364/413.01
`5,303,148 A
`4/1994 Senter et al. .................... 623/17
`5,306,307 A
`4/1994 Stone et al. ..................... 623/18
`5,306,311 A
`5/1994 Oka et al. ........................ 623/18
`5,314,478 A
`5,314,482 A * 5/1994 Goodfellow et al. ...... 623/20.35
`5,320,102 A
`6/1994 Paul et al.
`128/653.2
`
`-2-
`
`

`
`US 9,055,953 B2
`Page 3
`
`(56)
`
`References Cited
`
`U.S. PATENT DOCUMENTS
`
`5,326,363 A
`5,326,365 A
`5,344,459 A
`5,360,446 A
`5,365,996 A
`5,368,858 A
`5,380,332 A
`5,387,216 A
`5,403,319 A *
`5,413,116 A
`5,423,828 A
`5,433,215 A
`5,437,676 A
`5,445,152 A
`5,448,489 A
`5,452,407 A
`5,468,787 A
`5,474,559 A
`5,478,739 A
`5,486,180 A
`5,489,309 A
`5,501,687 A
`5,503,162 A
`5,507,820 A
`5,510,121 A
`5,522,900 A
`5,523,843 A
`5,540,696 A
`5,541,515 A
`5,542,947 A
`5,549,690 A
`5,554,190 A
`5,556,432 A
`
`5,560,096 A
`5,564,437 A
`5,571,191 A
`5,571,205 A
`5,575,793 A
`5,578,037 A
`5,593,450 A
`5,597,379 A
`5,601,563 A
`5,609,640 A
`5,611,802 A
`5,613,970 A
`5,616,146 A
`5,630,820 A
`5,632,745 A
`5,649,929 A
`5,658,291 A
`5,671,741 A
`5,681,316 A
`5,681,354 A
`5,682,886 A
`5,683,466 A
`5,683,468 A
`5,684,562 A
`5,687,210 A
`5,688,282 A
`5,690,635 A
`5,690,637 A
`5,702,463 A
`5,723,331 A
`5,728,162 A
`5,735,277 A
`5,737,506 A
`5,741,215 A
`5,749,362 A
`5,749,874 A
`5,749,876 A
`5,759,205 A
`5,766,259 A
`5,768,134 A
`5,769,092 A
`
`7I1994 Aikins ............................ 623/20
`7/1994 Alvine ............................ 623/21
`9/1994 Swartz ............................ 623/18
`1111994 Kennedy ......................... 623/16
`1111994 Crook .
`164/45
`1111994 Hunziker ...................... 424/423
`111995 Ferrante .......................... 606179
`2/1995 Thornhill et al. ............... 606/88
`4/1995 Matsen et al ................... 606/88
`5/1995 Radke et al.
`128/777
`6/1995 Benson ......................... 606/102
`7/1995 Athanasiou et al.
`128/774
`................. 606/88
`8/1995 Bouraly et al.
`8/1995 Bell et al.
`128/653.5
`9/1995 Reuben .................... 364/474.05
`9/1995 Crook ........................... 395/121
`1111995 Braden et al. ................. 523/113
`12/1995 Bertin et al.
`.................... 606/89
`12/1995 Slivka et al. ............. 435/240.23
`111996 Dietz et al. ...................... 606/87
`2/1996 Lackey et al. ................... 623/19
`3/1996 Willert et al .................... 606/94
`4/1996 Athanasiou et al.
`128/774
`411996 Pappas ............................ 623/20
`4/1996 Rhee et al. .................... 424/520
`6/1996 Hollister ......................... 623/18
`6/1996 Yamane et al.
`............... 356/363
`7I1996 Booth, Jr. et al. ............... 606/88
`7/1996 Tsujita .......................... 324/318
`8/ 1996 Treacy ............................ 606/88
`8/ 1996 Hollister et al.
`................ 623/21
`9/1996 Draenert ......................... 623/16
`9/1996 Kubein-Meesenburg
`............................... 623/20
`et al.
`10/1996 Stephens ......................... 29/558
`10/1996 Bainville et al.
`128/774
`1111996 Fitz ................................. 623/17
`1111996 James ............................. 623/24
`1111996 Carls et al. ...................... 606/80
`1111996 Sanders et al. .................. 606/80
`111997 Scott et al. ...................... 623/20
`111997 Haines et al. ................... 606/80
`2/1997 Burke et al ..................... 606/86
`3/ 1997 Johnson .......................... 623/20
`3/1997 Samuelson et al .............. 606/86
`3/ 1997 Houston et al. ................. 606/88
`411997 Murray ........................... 606/80
`511997 Todd ............................... 606190
`511997 Schwartz ........................ 60617 5
`7/1997 Callaway ........................ 606/88
`8/1997 Techiera ......................... 606/80
`9/1997 Lang et al.
`128/653.2
`10/ 1997 DeOrio et al. .................. 606/88
`10/ 1997 Eckhoff .......................... 623/20
`1111997 Delp et al.
`128/653.l
`1111997 Vitale ............................. 623/18
`1111997 Pappas ............................ 623/20
`1111997 Fujieda ......................... 3511212
`1111997 Maitrejean et al. ............. 378/57
`1111997 Baron et al.
`.................... 606190
`1111997 Matsen, III et al ............. 606/88
`1111997 Wen et al. ....................... 606/88
`12/1997 Pothier et al. ................... 623/20
`3/ 1998 Tubo et al. .................... 435/366
`3/ 1998 Eckhoff .......................... 623/20
`4/1998 Schuster
`128/653.l
`4/1998 McKenna et al. ............. 395/125
`4/1998 D'Urso ......................... 600/407
`5/1998 Funda et al.
`128/653.l
`511998 Schwartz ........................ 60617 5
`511998 Duvillier et al. ................ 606/88
`6/1998 Valentini ......................... 623/16
`611998 Sanunarco ...................... 623/21
`6/1998 Swaelens et al. ........ 364/468.28
`128/898
`6/1998 Williamson, Jr.
`
`5,769,899 A
`5,772,595 A
`5,776,137 A
`5,779,651 A
`5,786,217 A
`5,795,353 A
`5,800,438 A
`5,810,006 A
`5,824,085 A
`5,824,102 A
`5,827,289 A
`5,830,216 A
`5,832,422 A
`5,835,619 A
`5,842,477 A
`5,847,804 A
`5,853,746 A
`5,860,981 A
`5,871,018 A
`5,871,540 A
`5,871,542 A
`5,871,546 A
`5,879,390 A
`
`5,880,976 A
`5,885,296 A
`5,885,297 A
`5,885,298 A
`5,897,559 A
`5,899,859 A
`5,900,245 A
`5,906,643 A
`5,906,934 A
`5,911,723 A
`5,913,821 A
`5,916,220 A
`5,928,945 A
`5,939,323 A
`5,961,523 A
`5,968,051 A
`5,968,099 A
`5,972,385 A
`5,995,738 A
`6,001,895 A
`6,002,859 A
`6,007,537 A
`6,010,509 A
`6,013,103 A
`6,046,379 A
`6,056,754 A
`6,056,756 A
`6,057,927 A
`6,077,270 A
`6,078,680 A
`6,081,577 A
`6,082,364 A
`6,090,144 A
`6,093,204 A
`6,096,043 A
`6,102,916 A
`6,102,955 A
`6,106,529 A
`6,110,209 A
`6,112,109 A
`6,120,541 A
`6,120,543 A
`
`6,126,690 A
`6,139,578 A
`6,146,422 A
`6,151,521 A
`6,152,960 A
`6,156,069 A
`6,161,080 A
`6,162,208 A
`6,165,221 A
`6,171,340 Bl
`6,175,655 Bl
`6,178,225 Bl
`
`6/1998
`6/1998
`7/1998
`7/1998
`7/1998
`8/1998
`9/1998
`9/1998
`10/1998
`10/1998
`10/1998
`1111998
`1111998
`1111998
`12/1998
`12/1998
`12/1998
`111999
`2/1999
`2/1999
`2/1999
`2/1999
`3/1999
`
`3/1999
`3/1999
`3/1999
`3/1999
`4/1999
`5/1999
`5/1999
`5/1999
`5/1999
`6/1999
`6/1999
`6/1999
`7/1999
`8/1999
`10/1999
`10/1999
`10/1999
`10/1999
`1111999
`12/1999
`12/1999
`12/1999
`1/2000
`1/2000
`412000
`512000
`512000
`512000
`612000
`612000
`612000
`712000
`712000
`712000
`8/2000
`8/2000
`8/2000
`8/2000
`8/2000
`8/2000
`912000
`912000
`
`10/2000
`10/2000
`11/2000
`11/2000
`11/2000
`12/2000
`12/2000
`12/2000
`12/2000
`112001
`112001
`112001
`
`. . . . . . . . . . . . . . . 623/ 18
`Schwartz et al.
`Votruba et al. ................ 600/415
`Katz ............................... 606/88
`Buschmann et al .......... 600/587
`Tubo et al. .................... 435/402
`Felt ................................. 623/18
`Tuke et al.
`...................... 606190
`Votruba et al.
`128/653.2
`Sahay et al.
`. . . . . . . . . . . . . . . . . . . . 623/ 16
`Buscayret ....................... 623/20
`Reiley et al. .................... 606/86
`Insall et al. ..................... 606/88
`Wiedenhoefer ............... 702/154
`Morimoto et al. ............ 382/132
`Naughton et al.
`128/898
`Sarver et al. .................. 3511206
`Hunziker ...................... 424/426
`.................... 606/89
`Bertin et al.
`Delp et al.
`128/898
`Weissman et al. .............. 623/20
`Goodfellow et al ............ 623/20
`Colleran et al.
`................ 623/20
`Kubein-Meesenburg
`............................... 623/20
`et al.
`DiGioia, III et al .......... 364/578
`Masini ............................ 606/86
`Matsen, III ..................... 606/87
`Herrington et al .............. 606/88
`Masini ............................ 606/86
`Votruba et al. ................ 600/415
`Sawhney et al ............... 424/426
`Walker ............................ 623/20
`Grande et al.
`................ 435/325
`Ashby et al. .................... 606/88
`Farese et al. .................. 600/425
`Masini ............................ 606/88
`Seliktar et al. ................ 435/395
`Valentini et al ............... 435/395
`Masini ............................ 606/86
`Luckman et al. ............... 606/88
`Badorf et al. ................... 623/20
`Liu et al. ....................... 424/486
`DiGioia, III et al ..... 395/500.32
`Harvey et al. ................. 523/113
`DiGioia, III et al ..... 395/500.32
`Burkinshaw et al. ........... 606/66
`Delgado et al. ................. 606/88
`Kaufman et al.
`............... 623/20
`Stone et al. . . . . . . . . . . . . . . . . . . . . . 623/ 11
`Haines et al. ................... 606/80
`Eng et al. ........................ 606/87
`Levesque et al. .......... 356/432 T
`Katz ............................... 606/88
`Yoshida et al.
`............... 382/128
`Webber ........................... 378/23
`Balian et al.
`128/898
`Letot et al. ...................... 623/20
`Stone ......................... 623/14.12
`Techiera et al .................. 606/88
`Masini ............................ 606/88
`Mendes et al. .................. 623/20
`Techiera ......................... 606/88
`Stone ......................... 623/16.11
`D'Urso ......................... 600/407
`Johnson ..................... 623/14.12
`Kubein-Meesenburg
`............................... 623/20
`et al.
`Ateshian et al. . . . . . . . . . . . . . . . . 623/ 18
`Lee eta!. ................... 623/16.11
`Lawson ..................... 623/17.16
`Guo et al.
`..................... 600/407
`Pappas ....................... 623/20.31
`Amstutz .................... 623/22.11
`Aouni-Ateshian et al. ..... 703/11
`Hipps . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 606/ 1
`Schmotzer ................. 623/20.11
`McDowell ................. 623/18.11
`George, III et al. ........... 382/257
`Zur et al.
`. .................... 378/98.2
`
`-3-
`
`

`
`US 9,055,953 B2
`Page 4
`
`(56)
`
`References Cited
`
`U.S. PATENT DOCUMENTS
`
`6,187,010 Bl
`6,197,064 Bl
`6,197,325 Bl
`6,200,606 Bl
`6,203,546 Bl
`6,203,576 Bl
`6,205,411 Bl
`6,206,927 Bl
`6,214,369 Bl
`6,217,894 Bl
`6,219,571 Bl
`6,224,632 Bl
`6,235,060 Bl
`
`6,249,692 Bl
`6,251,143 Bl
`6,254,639 Bl
`6,261,296 Bl
`6,277,151 Bl
`6,281,195 Bl
`6,283,980 Bl
`6,289,115 Bl
`6,289,753 Bl
`6,296,646 Bl
`6,299,645 Bl
`6,299,905 Bl
`6,302,582 Bl
`6,310,477 Bl
`6,310,619 Bl
`6,316,153 Bl
`6,319,712 Bl
`6,322,588 Bl
`6,328,765 Bl
`6,334,006 Bl
`6,334,066 Bl
`6,342,075 Bl
`6,344,043 Bl
`6,344,059 Bl
`6,352,558 Bl
`6,358,253 Bl
`6,365,405 Bl
`6,371,958 Bl
`6,373,250 Bl
`6,375,658 Bl
`6,379,367 Bl
`6,379,388 Bl
`6,382,028 Bl
`6,383,228 Bl
`6,387,131 Bl
`6,429,013 Bl
`6,443,988 B2
`6,443,991 Bl
`6,444,222 Bl
`6,450,978 Bl
`6,459,948 Bl
`6,468,314 B2
`6,478,799 Bl
`6,479,996 Bl
`6,482,209 Bl
`6,510,334 Bl *
`6,514,514 Bl
`6,520,964 B2
`6,533,737 Bl
`6,556,855 B2
`6,558,421 Bl
`6,560,476 Bl
`6,575,980 Bl
`6,589,281 B2
`6,591,581 B2
`6,592,624 Bl
`6,620,168 Bl
`6,623,526 Bl
`6,626,945 B2
`6,626,948 B2
`6,632,225 B2
`
`212001 Masini ............................ 606/86
`3/2001 Haines et al. .............. 623/20.31
`3/2001 MacPhee et al .............. 424/426
`3/2001 Peterson et al.
`.............. 424/574
`3/2001 MacMahon ..................... 606/87
`3/2001 Afriat et al. ................ 623/20.27
`3/2001 Di Gioia, III et al.
`........... 703/11
`3/2001 Fell et al. ................... 623/20.29
`412001 Grande et al.
`. ............... 424/423
`412001 Sawhney et al ............... 424/426
`412001 Hargreaves et al.
`.......... 600/410
`512001 Pappas et al. .............. 623/20.34
`5/2001 Kubein-Meesenburg
`et al.
`.......................... 623/20.31
`612001 Cowin .......................... 600/407
`.......... 623/23.72
`6/2001 Schwartz et al.
`7/2001 Peckitt ....................... 623/11.11
`712001 Aebi et al.
`...................... 606190
`8/2001 Lee et al .................... 623/23.61
`8/2001 Rueger et al. ................... 514/21
`9/2001 Vibe-Hansen et al.
`....... 606/151
`912001 Takeo ........................... 382/130
`912001 Basser et al. .................... 73/866
`10/2001 Williamson .................... 606190
`10/2001 Ogden ....................... 623/20.21
`10/2001 Peterson et al.
`.............. 424/486
`10/2001 Nord et al. .................... 378/207
`10/2001 Schneider ..................... 324/307
`10/2001 Rice .............................. 345/420
`1112001 Goodman et al.
`................ 430/8
`............... 435/395
`1112001 Meenen et al.
`1112001 Ogle et al.
`................... 623/1.46
`12/2001 Hardwick et al.
`......... 623/23.72
`12/2001 Tanabe ............................ 385/12
`12/2001 Rupprecht et al. ............ 600/411
`112002 MacArthur ................ 623/20.14
`212002 Pappas ............................ 606/96
`212002 Krakovits et al. .......... 623/20.31
`3/2002 Spector ...................... 623/18.11
`3/2002 Torrie et al. ..................... 606/96
`412002 Salzmann et al.
`............ 435/366
`412002 Overaker ........................ 606172
`412002 Tsoref et al ................... 324/309
`412002 Hangody et al ................. 606/80
`412002 Vibe-Hansen et al.
`....... 606/151
`412002 Ensign et al. .............. 623/20.34
`512002 Wooh et al. ..................... 73/602
`512002 Schmotzer ................. 623/23.35
`512002 Miehlke et al. ............ 623/20.15
`8/2002 Halvorsen et al. ............ 435/377
`912002 Felt et al. ................... 623/17.12
`912002 Running .................... 623/20.27
`912002 Asculai et al. ................ 424/484
`912002 Brosseau et al ............... 600/595
`10/2002 Ateshian et al. .............. 700/117
`.......... 623/23.72
`10/2002 Schwartz et al.
`1112002 Williamson .................... 606190
`1112002 Hoogeveen et al. .......... 324/309
`1112002 Engh et al. ...................... 606179
`112003 Schuster et al.
`.............. 600/407
`212003 Atkinson et al ............... 424/423
`212003 Tallarida et al. .............. 396/567
`3/2003 Brosseau et al ............... 600/595
`4/2003 Thesen ......................... 600/419
`5/2003 Fell et al. ................... 623/14.12
`5/2003 Pelletier et al ................ 600/410
`6/2003 Robie et al. ..................... 606/88
`7/2003 Hyde, Jr ..................... 623/18.11
`7/2003 Schmieding .................... 53/396
`7/2003 Fraser et al.
`............... 623/17.16
`9/2003 Lombardo et al. .............. 606/88
`9/2003 Lloyd ........................ 623/20.28
`9/2003 Simon et al ................ 623/17.19
`9/2003 Storer et al.
`............... 623/23 .14
`10/2003 Sanford et al. .................. 606/87
`
`6,632,235 B2
`6,652,587 B2
`6,673,077 Bl
`6,673,116 B2
`6,679,917 B2
`6,690,816 B2
`6,692,448 B2
`6,702,821 B2
`6,712,856 Bl *
`6,719,794 B2
`6,770,078 B2 *
`6,772,026 B2
`6,799,066 B2
`6,816,607 B2
`6,835,377 B2
`6,855,165 B2
`6,873,741 B2
`6,875,218 B2
`6,893,463 B2
`6,893,467 Bl
`6,902,582 B2
`
`6,905,514 B2
`6,911,044 B2
`6,916,341 B2
`6,923,831 B2
`6,928,742 B2
`6,932,842 Bl
`6,964,687 Bl
`6,966,928 B2
`6,969,393 B2
`6,984,249 B2
`6,984,981 B2
`6,998,841 Bl
`7,008,430 B2
`7,020,314 Bl
`7,048,741 B2
`7,050,534 B2
`7,058,159 B2
`7,058,209 B2
`7,060,074 B2
`7,060,101 B2
`7,104,997 B2
`7,105,026 B2
`7,106,479 B2
`7,115,131 B2
`7,117,027 B2
`7,141,053 B2
`7,174,282 B2
`7,184,814 B2
`7,204,807 B2
`7,238,203 B2
`7 ,239 ,908 B 1
`7,244,273 B2
`7,245,697 B2
`7,282,054 B2
`7,292,674 B2
`7,326,252 B2
`7,379,529 B2
`7,427,200 B2
`7,438,685 B2
`7,442,196 B2
`7,467,892 B2
`7,468,075 B2 *
`7,517,358 B2
`7,520,901 B2
`7,534,263 B2
`7,603,192 B2
`7,611,519 B2
`7,611,653 Bl
`7,615,054 Bl*
`7,618,451 B2
`7,634,119 B2
`7,695,477 B2
`7,747,305 B2
`7,758,651 B2
`7,796,791 B2
`7,799,077 B2
`7,806,896 Bl
`
`10/2003 Weikel et al .................. 606/192
`1112003 Felt et al. ................... 623/20.16
`112004 Katz ............................... 606/88
`112004 Reiley ........................ 623/21.18
`112004 Ek .............................. 623/20.14
`212004 Aylward et al. ............... 382/128
`212004 Tanaka et al. ................. 600/587
`3/2004 Bonutti ........................... 606/88
`3/2004 Carignan et al ............ 623/20.35
`412004 Gerber et al. .............. 623/17.11
`8/2004 Bonutti ........................... 606/88
`8/2004 Bradbury et al ................ 700/98
`912004 Steines et al .................. 600/407
`1112004 O'Donnell et al. ........... 382/131
`12/2004 Goldberg et al ............. 424/93.7
`212005 Fell et al. ................... 623/14.12
`3/2005 Li
`................................. 382/266
`412005 Dye et al. ........................ 606/91
`512005 Fell et al. ................... 623/14.12
`512005 Bercovy ..................... 623/20.14
`6/2005 Kubein-Meesenburg
`et al.
`.......................... 623/20.31
`6/2005 Carignan et al ............ 623/20.35
`6/2005 Fell et al. ................... 623/14.12
`7/2005 Rolston ........................ 623/20.3
`8/2005 Fell et al. ................... 623/14.12
`8/2005 Broers et al. .................... 33/512
`8/2005 Litschko et al ............ 623/16.11
`1112005 Bernard et al.
`. ........... 623/17.16
`1112005 Fell eta!. ................... 623/14.12
`1112005 Pinczewski et al. ............ 606/88
`112006 Keller ........................ 623/20.24
`112006 Tamez-Pena et al. ......... 324/309
`212006 Tamez-Pena et al. ......... 324/302
`3/2006 Dong et al. ..................... 606/80
`3/2006 Suri et al. ...................... 382/130
`512006 Swanson ......................... 606/88
`512006 Lang ............................... 378/54
`612006 Lang et al. ...................... 378/54
`612006 Chen et al. .................... 382/117
`612006 Rosa et al.
`...................... 606/88
`612006 O'Connor et al. ......... 623/20.32
`912006 Lionberger et al. ............. 606/88
`912006 Johnson et al ............. 623/20.14
`912006 Roy et al ...................... 358/3.27
`10/2006 Engh et al. ...................... 606179
`10/2006 Zheng et al ................... 6001426
`1112006 Rosa et al.
`...................... 606/86
`212007 Hollister et al.
`.................. 703/2
`212007 Lang et al. .................... 600/416
`4/2007 Tsoref ........................... 600/438
`7/2007 Baggaetal. ............... 623/17.11
`7/2007 Alexander et al ............. 600/427
`7/2007 Pedersen et al ............ 623/14.12
`7/2007 Lang ............................... 378/54
`10/2007 Steffensmeier et al ......... 606/96
`1112007 Lang ............................... 378/54
`2/2008 Otto et al ................... 623/20.15
`5/2008 Lang ............................... 378/54
`9/2008 Noble et al.
`.................. 434/274
`10/2008 Burdette et al.
`.............. 600/439
`.................... 606/88
`10/2008 Fisher et al.
`12/2008 Lang et al. .................... 378/207
`12/2008 Lang et al. ................. 623/16.11
`412009 Petersen ....................... 606/247
`412009 Engh et al. ................. 623/20.21
`512009 Burdulis, Jr. et al. ...... 623/14.12
`10/2009 Martin et al.
`................... 700/98
`1112009 Lefevre et al. ................ 606/102
`1112009 Elsner et al ................... 264/255
`1112009 Bonutti ........................... 606/88
`1112009 Berez et al. ................ 623/14.12
`12/2009 Tsougarakis et al. ......... 382/128
`412010 Creger et al.
`. .................. 606/87
`612010 Dean et al. .................... 600/407
`7/2010 Chauhan et al. ........... 623/20.18
`912010 Tsougarakis et al. ......... 382/128
`9/2010 Lang et al. ................. 623/14.12
`10/2010 Bonutti
`606/86 R
`
`-4-
`
`

`
`US 9,055,953 B2
`Page 5
`
`(56)
`
`References Cited
`
`U.S. PATENT DOCUMENTS
`
`7,833,275 B2
`7,842,092 B2
`7,881,768 B2 *
`7,914,582 B2
`7,935,151 B2
`7,981,158 B2
`7,983,777 B2
`8,036,729 B2
`8,062,302 B2
`8,066,708 B2
`8,070,821 B2
`8,077,950 B2
`8,083,745 B2
`8,092,462 B2
`8,094,900 B2
`8,105,330 B2 *
`8,109,942 B2
`8,112,142 B2
`8,122,582 B2
`8,123,753 B2
`RE43,282 E
`8,167,888 B2
`8,192,498 B2
`8,211,181 B2
`8,234,097 B2
`8,236,061 B2
`8,257,360 B2
`8,265,730 B2
`8,306,601 B2
`8,337,501 B2
`8,337,503 B2
`8,337,507 B2
`8,343,218 B2
`8,352,056 B2
`8,357,111 B2
`8,357,166 B2
`8,366,771 B2
`8,369,926 B2
`8,377,066 B2
`8,377,068 B2
`8,377,073 B2
`8,377,129 B2
`8,439,926 B2
`8,460,304 B2
`8,480,754 B2
`8,500,740 B2
`8,529,568 B2
`8,529,630 B2
`8,545,569 B2
`8,551,099 B2
`8,551,102 B2
`8,551,103 B2
`8,551,169 B2
`8,556,906 B2
`8,556,907 B2
`8,556,971 B2
`8,556,983 B2
`8,561,278 B2
`8,562,611 B2
`8,562,618 B2
`8,568,479 B2
`8,568,480 B2
`8,617,172 B2
`8,617,242 B2
`8,623,026 B2
`8,634,617 B2
`8,638,998 B2
`8,641,716 B2
`8,657,827 B2
`8,682,052 B2
`8,690,945 B2
`8,709,089 B2
`8,735,773 B2
`8,768,028 B2
`8,771,365 B2
`
`............... 623/22.11
`1112010 Mears et al.
`1112010 Otto et al. .................. 623/18.11
`212011 Lang et al. .................... 600/407
`3/2011 Feltetal. ................... 623/20.16
`512011 Haines ....................... 623/20.35
`7/2011 Fitz eta!. ................... 623/17.16
`712011 Melton et al. ................... 700/98
`10/2011 Lang et al. .................... 600/407
`1112011 Lang et al. ...................... 606/87
`1112011 Lang et al. ...................... 606/88
`12/2011 Roger ........................ 623/20.17
`12/2011 Tsougarakis et al. ......... 382/128
`12/2011 Lang et al. ...................... 606/87
`112012 Pinczewski et al. ............ 606/88
`112012 Steines et al. ................. 382/128
`112012 Fitz et al. ........................ 606/88
`212012 Carson .......................... 606/130
`212012 Alexander et al. ............ 600/407
`212012 Burdulis, Jr. et al. ........ 29/527.1
`212012 Poncet ............................ 606/87
`3/2012 Alexander et al.
`512012 Steffensmeier ................. 606/88
`6/2012 Wagner et al. ............. 623/20.21
`7/2012 Walker ....................... 623/20.21
`7/2012 Steines et al. ..................... 703/1
`........... 623/20.31
`8/2012 Heldreth et al.
`912012 Richard et al. .................. 606/88
`9/2012 Alexander et al. ............ 600/410
`1112012 Lang et al. .................... 600/407
`12/2012 Fitz et al.
`606/86 R
`12/2012 Lian ................................ 606/87
`12/2012 Lang et