UNITED STATES PATENT AND TRADEMARK OFFICE
`
`CERTIFICATE OF CORRECTION
`
`PATENT NO.
`APPLICATION NO.
`
`: 9,562,263 B2
`: 14/067620
`
`DATED
`INVENTOR(S)
`
`: February 7, 2017
`: Brian K. Maplesetal.
`
`Page 1 of 1
`
`It is certified that error appears in the above-identified patent and that said Letters Patent is hereby corrected as shownbelow:
`
`In the Claims
`
`Column 34, Line 63, Claim 23, after “sequence”insert -- , --
`
`Signed and Sealedthis
`Twenty-sixth Day of September, 2017
`
`oe
`‘
`wy ,
`#
`Pb? fe
`fe
`aa
`Oe ep or
`RP Set Bi"
`
`
`Joseph Matal
`Performing the Functions and Duties ofthe
`Under Secretary of Commercefor Intellectual Property and
`Director ofthe United States Patent and Trademark Office
`
`1
`
`ELIX 1009
`
`1
`
`ELIX 1009
`
`

`

`Attorney's Docket No.: 30171-0025002 / ITI-001
`
`IN THE UNITED STATES PATENT AND TRADEMARKOFFICE
`
`First Named Inventor
`Patent No.
`Issue Date
`Serial No.
`Filed
`Title
`
`: Brian K. Maples
`:
`9,562,263
`:
`February 7, 2017
`:
` 14/067,620
`October 30, 2013
`> NICKING AND EXTENSION AMPLIFICATION REACTION FOR THE
`EXPONENTIAL AMPLIFICATION OF NUCLEIC ACIDS
`
`Art Unit
`Examiner
`Conf. No.
`
`: 1637
`: Angela Marie Bertagna
`: 4288
`
`Attention Certificate of Corrections Branch
`Commissioner for Patents
`P.O. Box 1450
`Alexandria, VA 22313-1450
`
`REQUEST FOR CERTIFICATE OF CORRECTION
`
`Please issue a certificate of correction in accordance with the attached form.
`
`All errors to be corrected were made in printing by the Patent and Trademark Office, and
`
`no fee is believed to be due.
`
`Apply any other necessary charges or credits to Deposit Account 06- 1050, referencing
`
`the above attorney docket number.
`
`Respectfully submitted,
`
`Man J.S. Lodovice, Reg. No. 59,749/
`lan J. Lodovice
`Reg. No. 59,749
`
`Date: March 9, 2017
`
`Customer Number 26161
`Fish & Richardson P.C.
`Telephone: (617) 956-5972
`Facsimile:
`(877) 769-7945
`
`23623696.doc
`
`2
`
`

`

`PTO/SB/44 (09-07)
`Approved for use through 08/31/2013. OMB 0651-0033
`U.S. Patent and Trademark Office; U.S. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unlessit displays a valid OMB control number.
`(Also Form PTO-1050)
`
`
`
`UNITED STATES PATENT AND TRADEMARKOFFICE
`CERTIFICATE OF CORRECTION
`
`Page 1 of 1
`
`PATENT NO.
`
`>
`
`9 562,263
`
`APPLICATION NO.:
`
`14/067 ,620
`
`ISSUE DATE
`
`:
`
`February 7, 2017
`
`
`
`:
`
`INVENTOR(S)
`
`Brian K. Maples, Rebecca C. Holmberg, Andrew P. Miller, Ph.D., Jarrod Provins, Richard Roth,
`Jeffrey Mandell and
`It is certified that an error appears or errors appear in the above-identified patent and that said Letters Patent
`is hereby corrected as shown below:
`
`Col. 34, line 63, claim 23, after “sequence”insert - - , - -
`
`MAILING ADDRESS OF SENDER (Please do not use customer number below):
`Fish & Richardson P.C.
`P.O. Box 1022
`Minneapolis, MN 55440-1022
`
`This collection of information is required by 37 CFR 1.322, 1.323, and 1.324. The information is required to obtain or retain a benefit by the public whichis to file (and
`by the USPTOto process) an application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 1.0 hour to complete,
`including gathering, preparing, and submitting the completed application form to the USPTO.Timewill vary depending uponthe individual case. Any comments on the
`amountof time you require to complete this form and/or suggestions for reducing this burden, should be sent to the Chief Information Officer, U.S. Patent and
`Trademark Office, U.S. Department of Commerce, P.O. Box 1450, Alexandria, VA 22313-1450. DO NOT SEND FEES OR COMPLETED FORMSTO THIS
`ADDRESS. SENDTO:Attention Certificate of Corrections Branch, Commissioner for Patents, P.O. Box 1450, Alexandria, VA 22313-1450.
`
`if you need assistance in completing the form, cal! 1-800-PTO-9199 and selection option2.
`
`3
`
`

`

`Electronic AcknowledgementReceipt
`
`ee
`
`Title of Invention:
`
`Nicking and Extension Amplification Reaction for the Exponential
`Amplification of Nucleic Acids
`
`ee
`
`09:52:14
`
`First Named Inventor/Applicant Name:
`
`Brian K. Maples
`
`Customer Number:
`
`26161
`
`lan J.S. Lodovice/Mary Florczak
`
`Filer Authorized By:
`
`lan J.S. Lodovice
`
`Attorney Docket Number:
`
`30171-0025002 / ITI-001
`
`Receipt Date:
`
`Filing Date:
`
`Time Stamp:
`
`09-MAR-2017
`
`30-OCT-2013
`
`
`
`Application Type: Utility under 35 USC 111{a)
`
`Paymentinformation:
`
`Submitted with Payment
`
`Pages
`Multi
`File Size(Bytes)/
`Document Description
`Document
`
`
`
`Number Message Digest|Part/.zip|P (if appl.)
`130995
`
`Requestfor Certificate of Correction
`
`30171RequestCertCor.pdf
`
`77006677bc041750a03c6ec[3ac1a724b12
`
`450e
`
`4
`
`

`

`This Acknowledgement Receipt evidences receipt on the noted date by the USPTOofthe indicated documents,
`characterized by the applicant, and including page counts, where applicable.It serves as evidence of receipt similar to a
`Post Card, as described in MPEP 503.
`
`Total Files Size (in bytes)
`
`130995
`
`the application.
`
`NewInternational Application Filed with the USPTO as a Receiving Office
`If a new international application is being filed and the international application includes the necessary components for
`an international filing date (see PCT Article 11 and MPEP 1810), a Notification of the International Application Number
`and of the International Filing Date (Form PCT/RO/105)will be issued in due course, subject to prescriptions concerning
`national security, and the date shown on this Acknowledgement Receiptwill establish the international filing date of
`
`New Applications Under 35 U.S.C. 111
`If a new applicationis being filed and the application includes the necessary componentsfora filing date (see 37 CFR
`1.53(b)-(d) and MPEP 506), a Filing Receipt (37 CFR 1.54) will be issued in due course and the date shownon this
`Acknowledgement Receiptwill establish thefiling date of the application.
`
`National Stage of an International Application under 35 U.S.C. 371
`If a timely submission to enter the national stage of an international application is compliant with the conditions of 35
`U.S.C. 371 and other applicable requirements a Form PCT/DO/EO/903indicating acceptanceof the application as a
`national stage submission under35 U.S.C. 371 will be issued in addition to the Filing Receipt, in due course.
`
`5
`
`

`

`
`
`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`UNITED STATES DEPARTMENT OF COMMERCE
`United States Patent and ‘Trademark Office
`Address: COMMISSIONER FOR PATENTS
`P.O. Box 1450
`Alexandria, Virginia 22313-1450
`www .uspto.gov
`
`APPLICATION NO.
`
`14/067,620
`
`ISSUE DATE
`
`02/07/2017
`
`PATENT NO.
`
`9562263
`
`ATTORNEY DOCKET NO.
`
`CONFIRMATION NO.
`
`30171-0025002 / ITI-001
`
`4288
`
`26161
`
`7590
`
`OL/L8/2017
`
`FISH & RICHARDSONP.C. (BO)
`P.O. BOX 1022
`MINNEAPOLIS, MN 55440-1022
`
`The projected patent numberandissue date are specified above.
`
`ISSUE NOTIFICATION
`
`Determination of Patent Term Adjustment under 35 U.S.C. 154 (b)
`(application filed on or after May 29, 2000)
`
`The Patent Term Adjustmentis 0 day(s). Any patent to issue from the above-identified application will include
`an indication of the adjustmenton the front page.
`
`If a Continued Prosecution Application (CPA) wasfiled in the above-identified application, the filing date that
`determines Patent Term Adjustmentis the filing date of the most recent CPA.
`
`Applicant will be able to obtain more detailed information by accessing the Patent Application Information
`Retrieval (PAIR) WEBsite (http://pair-uspto.gov).
`
`Any questions regarding the Patent Term Extension or Adjustment determination should be directed to the
`Office of Patent Legal Administration at (571)-272-7702. Questions relating to issue and publication fee
`payments should be directed to the Application Assistance Unit (AAU) of the Office of Data Management
`(ODM)at (571)-272-4200.
`
`APPLICANT(s) (Please see PAIR WEBsite http://pair.uspto.gov for additional applicants):
`
`lontan ‘Technologies, Inc., San Diego, CA;
`Brian K. Maples, Lake Forest, CA;
`Rebecca C. Holmberg, San Diego, CA;
`Andrew P. Miller, San Diego, CA;
`Jarrod Provins, Dana Point, CA;
`Richard Roth, Carlsbad, CA;
`Jetfrey Mandell, San Diego, CA;
`
`The United States represents the largest, most dynamic marketplace in the world and is an unparalleled location
`for business investment, innovation, and commercialization of new technologies. The USA offers tremendous
`resources and advantages for those who invest and manufacture goods here. Through SelectUSA, our nation
`worksto encourage andfacilitate business investment. To learn more about why the USA is the best country in
`the world to develop technology, manufacture products, and grow your business, visit SelectUSA. gov.
`
`IR103 (Rey. 10/09)
`
`6
`
`

`

`IN THE UNITED STATES PATENT AND TRADEMARK OFFICE
`
`Attorney's Docket No.: 30171-0025002 / ITI-001
`
`First Named Inventor :
`Serial No.
`:
`Filed
`
`Title
`
`Brian K. Maples
`14/067,620
`October 30, 2013
`
`1637
`>
`Art Unit
`: Angela Marie Bertagna
`Examiner
`:
`4288
`Confirmation No.
`Notice of Allowance Date: December 15, 2016
`NICKING AND EXTENSION AMPLIFICATION REACTION FOR
`THE EXPONENTIAL AMPLIFICATION OF NUCLEIC ACIDS
`
`MAIL STOP ISSUE FEE
`Commissionerfor Patents
`P.O. Box 1450
`Alexandria, VA 22313-1450
`
`REPLY TO NOTICE OF ALLOWANCE
`
`In response to the Notice of Allowance dated December 15, 2016, enclosed is a
`
`completed Part B - Fee(s) Transmittal.
`
`The issue fee was previously paid on September 21, 2016 and nofee is believed to be
`
`due. However, please apply any necessary charges or credits to Deposit Account 06 1050,
`
`referencing the above attorney docket number.
`
`Respectfully submitted,
`
`lan JS. Lodovice, Reg. No. 59,749/
`Ian J. Lodovice
`Reg. No. 59,749
`
`Date: December 19, 2016
`
`Customer Number 26161
`Fish & Richardson P.C.
`Telephone: (617) 956-5972
`Facsimile:
`(877) 769-7945
`
`23598852.doc
`
`7
`
`

`

`PART B - FEE(S) TRANSMITTAL
`
`26161
`
`7590
`
`12/15/2016
`
`FISH & RICHARDSONP.C.
`P.O. BOX 1022
`“
`MINNEAPOLIS, MN 55440-1022
`
`30171-0025002
`Brian K. Maples
`10/30/2013
`14/067,620
`TITLE OF INVENTION: NICKING AND EXTENSION AMPLIFICATION REACTION FOR THE EXPONENTIAL AMPLIFICATION OF NUCLEIC ACIDS
`
`4288
`
`
`
`
`
`
`
`
`
`APPLN. TYPE PUBLICATION FEE DUE|PREV. PAID ISSUE FEEENTITY STATUS ISSUE FEE DUE TOTAL FEES) DUE DATE DUE
`
`nonprovisional
`LARGE
`$0
`$0
`$960.00
`$0
`03/15/2017
`EXAMINER
`ARTUNIT
`CLASS-SUBCLASS
`
`BERTAGNA, ANGELA MARIE
`
`1637
`
`1. Change of correspondence address or indication of "Fee Address" (37
`CFR 1.363).
`)
`[
`] Change of correspondence address (or Change of Correspondence]
`Address form PTO/SB/122) attached.
`[
`] "Fee Address" indication (or "Fee Address” Indication form
`PTO/SB/47; Rev 03-02 or more recent) attached. Use of a Customer
`Numberis required.
`
`Complete and send this form, together with applicable fee(s), to: Mail Mail Stop ISSUE FEE
`Commissionerfor Patents
`P.O. Box 1450
`Alexandria, Virginia 22313-1450
`or Fax (571)-273-2885
`INSTRUCTIONS: This form should be used for transmitting the ISSUE FEE and PUBLICATION FEE (if required). Blocks 1 through 5 should be completed where
`appropriate. All further correspondence including the Patent, advance orders and notification of maintenance fees will be mailed to the current correspondence address as
`indicated unless corrected below or directed otherwise in Block 1, by (a) specifying a new correspondence address; and/or (b) indicating a separate "FEE ADDRESS" for
`maintenance fee notifications.
`CURRENT CORRESPONDENCE ADDRESS(Note: Use Block 1 for any change of address)
`Note: A certificate of mailing can only be used for domestic mailings of the
`Fee(s) Transmittal. This certificate cannot be used for any other accompanying
`papers. Each additional paper, such as an assignment or formal drawing, must
`have its owncertificate of mailing or transmission.
`/
`/
`Certificate of Mailing or Transmission
`| hereby certify that this Kee(s) ‘Transmittal is being deposited with the United
`States Postal Service with sufficient postage forfirst class mail in an envelope
`addressed to the Mail Stop ISSUE FEE addiess above, or being facsimile
`
`transmitted to the USPTO (571) 273-2885, on the date indicated below.
`(Depositor's name)
`
`(Signature)
`Mate)
`
`APPLICATION NO.
`FILING DATE
`FIRST NAMED INVENTOR
`ATTORNEY DOCKET NO.
`CONFIRMATION NO,
`
`
`
`
`
`
`
`
`
`
`
`435-006120
`2. For printing on the patent front page, list
`(1) the namesofup to 3 registered patent attorneys
`gr agents OR,alternatively,
`(2) the nameofa single firm (having as a member a
`registered attorney or agent) and the names of up to
`2 registered patent attomeys or agents. If no name is
`listed, no namewill be printed.
`
`1 Fish & RichardsonP.C.
`2
`
`3
`
`w
`
`. ASSIGNEE NAME AND RESIDENCE DATA TO BE PRINTED ON THE PATENT(printor type)
`PLEASE NOTE: Unless an assignee is identified below, no assignee data will appear on the patent. If an assignee is identified below, the document has beenfiled for
`recordation as set forth in 37 CFR 3.11. Completion of this form is NOT a substitute for filing an assignment.
`
`(B) RESIDENCE: (CITY and STATE OR COUNTRY)
`(A) NAME OF ASSIGNEE
`Ionian Technologies, Inc.
`San Diego, CA
`Please check the appropriate assignee categoryor categories (will not be printed on the patent): [
`] Individual [X] Corporation or other private group entity [
`] Government
`
`4a. The following fee(s) are submitted:
`4b. Payment of Fee(s): (Please first reapply any previously paid issue fee shown above)
`[X] Issue Fee
`[
`] Acheck in the amount of the fee(s) is enclosed.
`[
`] Publication Fee (No small entity discount permitted)
`[
`] Payment by credit card. Form PTO-2038 is attached.
`[
`] Advance Order- # of Copies
`[X] The Director is hereby authorized to charge the required fee(s), or credit any overpayment, to
`Deposit Account Number 06-1050
`
`5. Change in Entity Status (fromstatus indicated above)
`[
`] Applicant certifying micro entity status. See 37 CFR 1.29
`
`|
`
`[
`
`| Applicantasserting small entity status. See 37 CFR 1.27.
`
`] Applicant changing to regular undiscounted fee status.
`
`NOTE: Absent a valid certification of Micro Entity Status (see form PTO/SB/15A and 15B), issue fee
`paymentin the micro entity amount will not be accepted at the risk of application abandonment.
`NOTE: If the application was previously under micro entitv status, checking this box will be
`taken to be a notification of loss of entitlement to micro entity status.
`NOTE: Checkingthis box will be takento be a notification of loss of entitlement to small or
`micro entity status, as applicable.
`The Director of the USPTOis requested to apply the Issue Fee and Publication Fee (if any) or to re-apply any previously paid issue fee to the application identified above.
`NOTE: TheIssuc Fee and Publication Fee (if required) will not be accepted from anyonc other than the applicant; a registered attorncy or agent; or the assignee orotherparty
`in interest as shown by the records of the United States Patent and Trademark Office.
`
`Date December 19, 2016
`Authorized Signature /Ian J.S. Lodovice, Reg. No. 59,749/
`59,749 Ian J. Lodovice Registration No.
`
`
`Typedor printed name
`
`
`
`23598864.doc
`
`8
`
`

`

`IN THE UNITED STATES PATENT AND TRADEMARK OFFICE
`
`Attorney's Docket No.: 30171-0025002 / ITI-001
`
`1637
`:
`Art Unit
`First Named Inventor : Brian K. Maples
`: Angela Marie Bertagna
`Examiner
`Serial No.
`>
`14/067,620
`:
`4288
`Conf. No.
`Filed
`: October 30, 2013
`Title
`: NICKING AND EXTENSION AMPLIFICATION REACTION FOR
`THE EXPONENTIAL AMPLIFICATION OF NUCLEIC ACIDS
`
`Mail Stop Amendment
`Commissionerfor Patents
`P.O. Box 1450
`Alexandria, VA 22313-1450
`
`INTERVIEW SUMMARY
`
`The undersigned representative thanks the Examiner for the courtesy of the telephonic
`
`interview held on November 29, 2016.
`
`The substance of the interview included a discussion of claims 67, 95, and 107 and the
`
`reference Nelson et al. During the interview, an agreement was reached on December1, 2016.
`
`Applicant acknowledges and thanks Examiner Bertagna for the Examiner-Initiated Interview
`
`Summary dated December 15, 2016.
`
`Respectfully submitted,
`
`an J.S. Lodovice, Reg. No. 59,749/
`Ian J. Lodovice
`Reg. No. 59,749
`
`Date: December 19, 2016
`
`Customer Number 26161
`Fish & Richardson P.C.
`Telephone: (617) 956-5972
`Facsimile:
`(877) 769-7945
`23398848.doc
`
`9
`
`

`

`14:44:33
`
`Electronic AcknowledgementReceipt
`
`ae
`
`e
`
`Title of Invention:
`
`Nicking and Extension Amplification Reaction for the Exponential
`Amplification of Nucleic Acids
`
`First Named Inventor/Applicant Name:
`
`Brian K. Maples
`
`Customer Number:
`
`26161
`
`lan J.S. Lodovice/StaceyHill
`
`Filer Authorized By:
`
`lan J.S. Lodovice
`
`Attorney Docket Number:
`
`30171-0025002 / ITI-001
`
`Receipt Date:
`
`Filing Date:
`
`Time Stamp:
`
`19-DEC-2016
`
`30-OCT-2013
`
`
`
`Application Type: Utility under 35 USC 111{a)
`
`Paymentinformation:
`
`Submitted with Payment
`
`Pages
`Multi
`File Size(Bytes)/
`Document Description
`Document
`
`
`
`Number Message Digest|Part/.zip|P (if appl.)
`196349
`
`Issue Fee Payment (PTO-85B)
`
`30171|ssueFee.pdf
`
`9d56425919s792d89Mlb240090337L27¢6
`
`68509
`
`10
`
`10
`
`

`

`Information:
`
`Applicant summaryof interview with
`.
`examiner
`
`30171002500215.pdf
`
`e5d6e1¢e15310983a2c328fch1 788d623de|
`
`Warnings:
`Information:
`
`Total Files Size (in bytes)
`
`267703
`
`This AcknowledgementReceipt evidences receipt on the noted date by the USPTO ofthe indicated documents,
`characterized by the applicant, and including page counts, where applicable. It serves as evidence of receipt similar to a
`Post Card, as described in MPEP 503.
`
`
`
`
`New Applications Under 35 U.S.C. 111
`If a new applicationis being filed and the application includes the necessary componentsfora filing date (see 37 CFR
`1.53(b)-(d) and MPEP 506), a Filing Receipt (37 CFR 1.54) will be issued in due course and the date shownonthis
`Acknowledgement Receiptwill establish thefiling date of the application.
`
`National Stage of an International Application under 35 U.S.C. 371
`If a timely submission to enter the national stage of an international application is compliant with the conditions of 35
`U.S.C. 371 and other applicable requirements a Form PCT/DO/EO/903indicating acceptanceof the application as a
`national stage submission under 35 U.S.C. 371 will be issued in addition to the Filing Receipt, in due course.
`
`New International Application Filed with the USPTO as a Receiving Office
`If a new international application is being filed and the international application includes the necessary components for
`an international filing date (see PCT Article 11 and MPEP 1810), a Notification of the International Application Number
`andof the International Filing Date (Form PCT/RO/105)will be issued in due course, subject to prescriptions concerning
`national security, and the date shown on this Acknowledgement Receiptwill establish the international filing date of
`the application.
`
`11
`
`11
`
`

`

`™ ~
`
`(Date)
`CONFIRMATION NO.
`
`PARTB - FEE(S) TRANSMITTAL
`
`sw
`
`Complete and send this form, together with applicable fee(s), to: Mail Mail Stop ISSUE FEE
`Commissioner for Patents
`P.O. Box 1450
`Alexandria, Virginia 22313-1450
`
`or Fax (571)-273-2885
`through 5 should be completed where
`INSTRUCTIONS: This form should be used for transmitting the ISSUE FEE and PUBLICATION FEE (if required). Blocks 1
`appropriate. All further correspondence including the Patent, advance orders and notification of maintenance fees will be mailed to the current correspondence address as
`indicated unless comected belowor directed otherwise in Block 1, by (a) specifying a new correspondence address; and/or (b) indicating a separate "FEE ADDRESS"for
`
`maintenancefee notifications.
`CURRENT CORRESPONDENCE ADDRESS(Note: Use Block | for any changeof address)
`Note: A certificate of mailing can only be used for domestic mailings of the
`Fee(s) Transmittal. This certificate cannot be used for any other accompanying
`papers. Each additional paper, such as an assignment or formal drawing, must
`have its owncertificate of mailing or transmission.
`Certificate of Mailing or Transmission
`I hereby certify that this Fee(s) Transmittal is being deposited with the United
`States Postal Service with sufficient postage for first class mail in an envelope
`addressed to the Mail Stop ISSUE FEE address above, or being facsimile
`transmitted to the USPTO (571) 273-2885, on the date indicated below.
`(Depositors name)
`(Signature)
`
`26161
`
`7590
`
`12/15/2016
`
`FISH & RICHARDSONP.C,
`P.O. BOX 1022
`MINNEAPOLIS, MN 55440-1022
`
`",od
`
`DEC 19 2016 &
`
`~
`
`APPLICATION NO
`
`FILING DATE
`
`FIRST NAMED INVENTOR
`
`ATTORNEY DOCKET NO.
`
`30171-0025002
`Brian K. Maples
`10/30/2013
`14/067,620
`TITLE OF INVENTION: NICKING AND EXTENSION AMPLIFICATION REACTION FOR THE EXPONENTIAL AMPLIFICATION OF NUCLEIC ACIDS
`
`
`4288
`
`
`
`APPLN. TYPE PUBLICATION FEE DUE|PREV. PAID ISSUE FEE|TOTAL FEE(S) DUEENTITY STATUS ISSUE FEE DUE
`
`
`
`
`
`nonprovisional
`
`LARGE
`
`$0
`
`$0
`
`$960.00
`
`$0
`
`03/15/2017
`
`435-006120
`BERTAGNA, ANGELA MARIE
`1637
`
`2, Forprinting onthe patent front page,list
`CRe)correspondence address or indication of “Fee Address" (37}
`(1) the namesof upto 3 registered patent attorneys
`or agents OR,alternatively,
`[
`] Change of correspondence address (or Change of Correspondence]
`Address form PTO/SB/122) attached.
`2)
`the nameof a single firm (having
`as a member a
`ae
`ge
`istered attomey oFagent) a thenames ofup to
`{
`] "Fee Address"indication (or "Fee Address" Indication form
`2 registered patent attorneysor agents, If no name is
`PTO/SB/47: Rev 03-02 or more recent) attached. Use of a Customer
`listed, no name will be printed.
`Numberis required.
`we . ASSIGNEE NAME AND RESIDENCE DATA TO BE PRINTED ON THE PATENT (printortype)
`PLEASE NOTE: Unless an assignee is identified below, no assignee data will appear on the patent. If an assignee is identified below, the document has been filed for
`recordation as set forth in 37 CFR 3.11. Completion ofthis form is NOT a substitute for filing an assignment.
`(A) NAME OF ASSIGNEE
`(B) RESIDENCE: (CITY and STATE OR COUNTRY)
`Ionian Technologies, Inc.
`San Diego, CA
`
`] Individual (X] Corporationorother private group entity [_] Government
`Please check the appropriate assignee category or categories(will not be printed on the patent): [_
`4a. The following fee(s) are submitted:
`4b, Paymentof Fee(s): (Please first reapply any previously paid issue fee shown above)
`[X] Issue Fee
`[
`] Acheck in the amountof the fee(s) is enclosed.
`[
`] Publication Fee (No small entity discount permitted)
`[
`| Paymentby credit card. Form PTO-2038 is attached.
`{
`] Advance Order- # of Copies
`[X] The Director is hereby authorized to charge the required fee(s), or credit any overpay ment, to
`Deposit Account Number 06-1050
`
`1 Fish & Richardson P.C.
`2
`
`3
`
`;
`
`5. Change in Entity Status (fromstatus indicated above)
`{
`] Applicant certifying micro entity status. See 37 CFR 1.29
`
`[
`
`[
`
`] Applicant asserting small entity status. See 37 CFR 1.27.
`
`] Applicant changingto regular undiscountedfee status.
`
`.
`NOTE:Absenta valid certification of Micro Entity Status (sec form PTO/SB/15A and 15B),issue fee
`paymentin the micro entity amountwill not be accepted at the risk of application abandonment.
`NOTE:If the application was previously under micro entity status, checking this box will be
`taken to be a notification of loss of entitlement to micro entity status.
`
`NOTE:Checkingthis box will be taken to be a notification of loss of entitlement to small or
`
`micro entity status, as applicable.
`The Director of the USPTOis requested to applythe Issue Fee and Publication Fee(if any) or to re-apply any previously paid issue fee to the application identified above.
`NOTE:The Issue Fee and Publication Fee(if required) will not be accepted from anyone other than the applicant;a registered attorney or agent;or the assignee or otherparty
`
`in interest as shownbythe records of the United States Patent and Trademark Office.
`
`Authorized Signature /lan J.S. Lodovice, Reg, No. 59,749/
`
`.
`
`Date December 19, 2016
`
`Typedor printed name
`_Ian J. Lodovice
`Registration No.
`_59,749
`
`
`oRajustwent date: 12/21/2816 SDIRETA2
`B3/22/eG16 INTEFSW 88885299 B61858
`Bl FCsi581
`966.88 CR
`
`14067626
`
`ya/ar/epie SDIR
`FCr1Sa4
`@i
`FL:
`
`5a
`cTA2 @8000003 86105
`369.08 DA
`
`14067620
`
`12
`
`12
`
`

`

`
`
`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`UNITED STATES DEPARTMENT OF COMMERCE
`United States Patent and Trademark Office
`Address: COMMISSIONER FOR PATENTS
`P.O. Box 1450
`Alexandria, Virginia 22313-1450
`www.uspto.gov
`
`NOTICE OF ALLOWANCE AND FEE(S) DUE
`
`26161
`
`7590
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`-
`12/15/2016
`
`FISH & RICHARDSONP.C. (BO)
`P.O. BOX 1022
`MINNEAPOLIS, MN 55440-1022
`
`EXAMINER
`
`BERTAGNA, ANGELA MARIE
`
`1637
`
`DATE MAILED: 12/15/2016
`
`APPLICATION NO.
`
`FILING DATE
`
`FIRST NAMED INVENTOR
`
`ATTORNEYDOCKET NO.
`
`CONFIRMATION NO.
`
`30171-0025002 / ITI-001
`Brian K. Maples
`10/30/2013
`14/067 ,620
`TITLE OF INVENTION: Nicking and Extension Amplification Reaction for the Exponential Amplification of Nucleic Acids
`
`4288
`
`
`
`
`
`
`
`
`
`
`
`APPIN. TYPR PUBLICATION FER DUP.|PREV. PAID ISSUE FRRENTITY STATUS ISSTTF FRE DUR TOTAT. FER(S) DUE DATE DUR
`
`
`
`nonprovisional
`
`UNDISCOUNTED
`
`$960
`
`$960
`
`03/15/2017
`
`THE APPLICATION IDENTIFIED ABOVE HAS BEEN EXAMINED AND IS ALLOWED FOR ISSUANCEAS A PATENT.
`PROSECUTION ON THE MERITS IS CLOSED. TITS NOTICE OF ALLOWANCEIS NOT A GRANT OF PATENT RIGIITS.
`THIS APPLICATION IS SUBJECT TO WITHDRAWAL FROM ISSUE AT THE INITIATIVE OF THE OFFICE OR UPON
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`THE ISSUE FEE AND PUBLICATION FEE (IF REQUIRED) MUST BE PAID WITHIN THREE MONTHS FROM THE
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`SEE 35 U.S.C. 151. THE ISSUE FEE DUE INDICATED ABOVE DOES
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`HOW TO REPLY TO THIS NOTICE:
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`I. Review the ENTITY STATUSshownabove.If the ENTITY STATUSis shown as SMALL or MICRO,verify whether entitlement to that
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`I. PART B - FEE(S) TRANSMITTAL,or its equivalent, must be completed and returned to the United States Patent and Trademark Office
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`
`PTOL-85 (Rev. 02/11)
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`Page 1 of 3
`
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`

`

`30171-0025002 / ITI-001
`Brian K. Maples
`10/30/2013
`14/067.620
`TITLE OF INVENTION: Nicking and Extension Amplification Reaction for the Exponential Amplification of Nuclcic Acids
`
`
`
`
`
`
`
`
`
`
`APPLN. TYPE PUBLICATION FEE DUE|PREV. PAID ISSLE FEEENTITY STATUS ISSUE FEE DUE TOTAL FEE(S) DUE DATE DUE
`
`PART B - FEE(S) TRANSMITTAL
`
`Complete and send this form, together with applicable fee(s), to: Mail Mail Stop ISSUE FEE
`Commissioner for Patents
`P.O. Box 1450
`Alexandria, Virginia 22313-1450
`or Fax (571)-273-2885
`
`INSTRUCTONS: ‘This form should be used for transmitting the ISSUE KEE and PUBLICATION FEE(if required). Blocks 1
`through 5 should be completed where
`ppropriate. All further correspondence including the Patent, advance orders and notification of maintenance fees will be mailed to the current correspondence address as
`Adicated unless corrected below or directed otherwise in Block 1, by (a) specifying a new correspondence address; and/or (b) indicating a separate "FEE ADDRESS"for
`maintenance feenotifications.
`Note: A certificate of mailing
`can only be used for domestic mailings of the
`Fee(s) Transmittal. This certificate cannot be used for any other accompanying
`apers. Each additional paper, such as an assignment or formal drawing, must
`have its own certificate of mailing or transmission.
`Certificate of Mailing or Transmission
`:
`:
`:
`soy
`oP
`-
`:
`:
`I hereby certify that this Kee(s) ‘lransmittal is being deposited with the United
`States Postal Service with sufficient postage for first class mail in an envelope
`addressed to the Mail Stop ISSUE FEE address above, or being facsimile
`transmitted to the USPTO (571) 273-2885, on the date indicated below.
`(epositor's name)
`(Signature)
`
`CURRENT CORRESPONDENCE ADDRESS(Note: Use Block | for any change of address)
`
`26161
`
`7590
`
`12/15/2016
`
`FISH & RICHARDSONP.C. (BO)
`P.O. BOX 1022
`MINNEAPOLIS, MN 55440-1022
`
`(Date)
`
`
`
`4288
`
`
`
`
`
`nonprovisional
`
`UNDISCOUNTTE:D
`
`$960
`
`03/15/2017
`
`EXAMINER
`
`ART UNIT
`
`CLASS-SUBCLASS
`
`BERTAGNA, ANGELA MARIE
`
`1637
`
`435-006120
`
`2. For printing on the patent front page,list
`1. Change of correspondence address or indication of "Fee Address" (37
`CFR 1.363).
`(1) The names of up to 3 registered patent attorneys
`LY changeof correspondenceaddress (or Change of Correspondence
`or agents OR,alternatively,
`Address foorm PTO/SB/122) attached.
`(2) The nameofa single firm (having as a member a
`registered attorney or agent) and the names of up to
`L] "Fee Address"indication (or "Fee Address" Indication form
`2 registered patentattorneys or agents. If no nameis
`PTO/SB/47, Rev 03-02 or more recent) attached. Use of a Customer
`listed, no namewill be printed.
`Numberis required.
`3. ASSIGNEE NAME AND RESIDENCE DATA 'TO BE PRINTED ON THE PATENT(printor type)
`If an assignee is identified below, the documenthas beenfiled for
`PLEASE NOTE: Unless an assignee is identified below, no assignee data will appear on the patent.
`recordation as set forth in 37 CFR 3.11. Completion of this form is NOT a substitute for filing an assignment.
`(A) NAMEOF ASSIGNEE
`(B) RESIDENCE: (CITY and STATE OR COUNTRY)
`
`
`
`
`
`2
`3
`
`
`
`Please check the appropriate assignee categoryor categories (will not be printed on the patent) :
`
`(CV individual LY Corporation or other private group entity (J Government
`
`Aa. ‘The following fee(s) are submitted:
`LB issue Fee
`LY Publication Fee (No small entity discount permitted)
`LY Advance Order - # of Copies
`
` LJ Applicant changing to regular undiscounted fee status.
`
`5. Change in Entity Status (from status indicated above)
`LJ Applicant certifying micro entity status. See 37 CFR 1.29
`
`LJ Applicantasserting small entity status. See 37 CFR 1.27
`
`4b. Paymentof Kee(s): (Pleasefirst reapply any previously paid issue fee shown above)
`LIA check is enclosed.
`Lj Paymentby credit card. Form PTO-2038 is attached.
`[_] The directoris herebyauthorized to charge the required fee(s), any deficiency, or credits any
`overpayment, to Deposit Account Number
`(enclose an extra copy of this form).
`
`
`
`
`NOTE:Absenta valid certification of Micro Entity Status (see forms PTO/SB/15A and 15B), issue
`fee paymentin the micro entity amountwill not be acceptedatthe risk of application abandonment.
`
`NOTE:If the application was previously under micro entity status, checking this box will be taken
`to be a notification of loss of entitlement to micro entity status.
`NOTE:Checking this box will be taken to be a notification of loss of entitlement to small or micro
`entity status, as applicable.
`
`NOTE:This form must be signed in accordance with 37 CER 1.31 and 1.33. See 37 CFR 14 for signature requirements and certifications.
`
`Date
`
`Registration No.
`
`Typed or printed name
`
`Authorized Signature
`
`PLOL-85 Part B (10-13) Approved for use through 10/31/2013.
`
`OMB 0651-0033
`
`U.S. Patentand ‘Trademark Office; U.S. DEPARTMENT OF COMMERCE
`
`Page 2 of 3
`
`14
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`14
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`

`

`
`
`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`UNITED STATES DEPARTMENT OF COMMERCE
`United States Patent and Trademark Office
`Address: COMMISSIONER FOR PATENTS
`P.O. Box 1450
`Alexandria, Virginia 22313-1450
`www.uspto.gov
`
`APPLICATION NO.
`
`FILING DATE
`
`FIRST NAMED INVENTOR
`
`ATTORNEYDOCKET NO.
`
`CONFIRMATION NO.
`
`
`
`14/067,620
`
`10/30/2013
`
`Brian K. Maples
`
`30171-0025002 / ITI-001
`
`4288
`
`26161
`
`7590
`
`|
`12/15/2016
`
`FISH & RICHARDSONP.C. (BO)
`P.O. BOX 1022
`M