UNITED STATES PATENT AND TRADEMARK OFFICE
`
`CERTIFICATE OF CORRECTION
`
`PATENT NO.
`APPLICATION NO.
`DATED
`
`INVENTOR(S)
`
`: 9,562,263 B2
`: 14/067620
`
`: February 7, 2017
`: Brian K. Maples et al.
`
`Page 1 of 1
`
`It is certified that error appears in the above-identified patent and that said Letters Patent is hereby corrected as shown below:
`
`In the Claims
`
`Column 34, Line 63, Claim 23, after “sequence” insert -- , --
`
`Signed and Sealed this
`
`Twenty-sixth Day of September, 2017
`
`‘
`
`-
`
`
`,
`ELK
`:1:
`‘
`175;; y {f
`Joseph Matal
`Performing the Functions and Duties ofthe
`Under Secretary of Commercefor Intellectual Property and
`Director ofthe United States Patent and Trademark Office
`
`. ”r w -’-
`.fx
`X”? 5 mi :33;
`
`ELIX 1009
`
`1
`
`ELIX 1009
`
`

`

`Attorney's Docket No.: 30171-0025002 / ITI-OOI
`
`IN THE UNITED STATES PATENT AND TRADEMARK OFFICE
`
`First Named Inventor
`Patent No.
`Issue Date
`Serial No.
`Filed
`Title
`
`: Brian K. Maples
`:
`9,562,263
`:
`February 7, 2017
`:
`14/067,620
`: October 30, 2013
`I NICKING AND EXTENSION AMPLIFICATION REACTION FOR THE
`EXPONENTIAL AMPLIFICATION OF NUCLEIC ACIDS
`
`Art Unit
`Examiner
`Conf. No.
`
`: 1637
`: Angela Marie Bertagna
`: 4288
`
`Attention Certificate of Corrections Branch
`Commissioner for Patents
`PO. Box 1450
`
`Alexandria, VA 22313—1450
`
`REQUEST FOR CERTIFICATE OF CORRECTION
`
`Please issue a certificate of correction in accordance with the attached form.
`
`All errors to be corrected were made in printing by the Patent and Trademark Office, and
`
`no fee is believed to be due.
`
`Apply any other necessary charges or credits to Deposit Account 06— 1050, referencing
`
`the above attorney docket number.
`
`Respectfully submitted,
`
`/Ian JS. Lodovice, Reg. No. 59,749/
`Ian J. Lodovice
`
`Reg. No. 59,749
`
`Date: March 9, 2017
`
`Customer Number 26161
`Fish & Richardson PC.
`
`Telephone: (617) 956-5972
`Facsimile:
`(877) 769-7945
`
`23623696.d0c
`
`2
`
`

`

`PTO/SB/44 (09-07)
`Approved for use through 08/31/2013. OMB 0651-0033
`U.S. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`Under the PapenNork Reduction Act of 1995, no persons are required to respond to a collection of information unless it displays a valid OMB control number.
`(Also Form PTO-1050)
`
`
`
`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`CERTIFICATE OF CORRECTION
`
`Page 1 of1
`
`PATENT NO.
`
`:
`
`9,562,263
`
`APPLICATION NO.:
`
`14/067,620
`
`ISSUE DATE
`
`:
`
`February 7, 2017
`
`:
`
`INVENTOR(S)
`
`Brian K. Maples, Rebecca C. Holmberg, Andrew P. Miller, Ph.D., Jarrod Provins, Richard Roth,
`Jeffrey Mandell and
`It is certified that an error appears or errors appear in the above-identified patent and that said Letters Patent
`is hereby corrected as shown below:
`
`Col. 34, line 63, claim 23, after “sequence” insert - - , - -
`
`
`
`
`
`MAILING ADDRESS OF SENDER (Please do not use customer number below):
`Fish & Richardson P.C.
`PO. Box 1022
`
`Minneapolis, MN 55440-1022
`
`This collection of information is required by 37 CFR 1.322, 1.323, and 1.324. The information is required to obtain or retain a benefit by the public which is to file (and
`by the USPTO to process) an application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is estimated to take 1.0 hourto complete,
`including gathering, preparing, and submitting the completed application form to the USPTO. Time will vary depending upon the individual case. Any comments on the
`amount of time you require to complete this form and/orsuggestions for reducing this burden, should be sent to the Chief Information Officer, US. Patent and
`Trademark Office. US. Department ofCommerce, PO. Box 1450, Alexandria, VA 22313-1450. DO NOT SEND FEES OR COMPLETED FORMS TO THIS
`ADDRESS. SEND TO: Attention Certificate of Corrections Branch, Commissioner for Patents, P.O. Box1450, Alexandria, VA 22313-1450.
`
`If you need assistance in completing the form, call 1-800-PTO-9199 and selection option2.
`
`3
`
`

`

`Electronic Acknowledgement Receipt
`
`“—
`
`——
`
`T'tle 0f lnventlon:
`
`Nicking and Extension Amplification Reaction forthe Exponential
`Amplification of Nucleic Acids
`
`
`
`First Named Inventor/Applicant Name:
`
`Brian K. Maples
`
`Customer Number:
`
`26161
`
`Ian J.S. Lodovice/Mary Florczak
`
`Filer Authorized By:
`
`Ian J.S. Lodovice
`
`Attorney Docket Number:
`
`3017170025002 / ITerO1
`
`Receipt Date:
`
`Filing Date:
`
`09—MAR—201 7
`
`30—OCT—201 3
`
`Time Stamp:
`
`09:52:14
`
`
`
`Application Type: Utility under 35 USC 111(a)
`
`Payment information:
`
`Submitted with Payment
`
`L506
`
`Document
`Number
`
`Document Descri
`
`tion
`
`p
`
`File SizelBytes)I
`Message Digest
`130995
`
`Pages
`Multi
`Part I.zip (if appl.)
`
`Request for Certificate of Correction
`
`30171 RequestCertCor.pdf
`
`77006677bc04|750d03L68Lli3dc1d724bl 2
`
`4
`
`

`

`This Acknowledgement Receipt evidences receipt on the noted date by the USPTO of the indicated documents,
`characterized by the applicant, and including page counts, where applicable. It serves as evidence of receipt similar to a
`Post Card, as described in MPEP 503.
`
`Total Files Size (in bytes)
`
`130995
`
`New Applications Under 35 U.S.C. 111
`lfa new application is being filed and the application includes the necessary components for a filing date (see 37 CFR
`1.53(b)—(d) and MPEP 506), a Filing Receipt (37 CFR 1.54) will be issued in due course and the date shown on this
`Acknowledgement Receipt will establish the filing date of the application.
`
`National Stage of an International Application under 35 U.S.C. 371
`If a timely submission to enter the national stage of an international application is compliant with the conditions of 35
`U.S.C. 371 and other applicable requirements a Form PCT/DOIEOI903 indicating acceptance of the application as a
`national stage submission under 35 U.S.C. 371 will be issued in addition to the Filing Receipt, in due course.
`
`the application.
`
`New International Application Filed with the USPTO as a Receiving Office
`lfa new international application is being filed and the international application includes the necessary components for
`an international filing date (see PCT Article 11 and MPEP 1810), a Notification of the International Application Number
`and of the International Filing Date (Form PCT/ROI105) will be issued in due course, subject to prescriptions concerning
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`
`5
`
`

`

`UNITED STATES PATENT AND TRADEMARK OEEICE
`
`
`
`UNITED STATES DEPARTMENT OF COMMERCE
`United States Patent and Trademark Office
`Address: COMIVIISS IONER FOR PATENTS
`PO Box 1450
`Alexandria Virginia 22313-1450
`www.uspt0 gov
`
`APPLICATION NO.
`
`14/067.620
`
`ISSUE DATE
`
`02/07/2017
`
`PATENT NO.
`
`9562263
`
`ATTORNEY DOCKET NO.
`
`CONFIRMATION NO.
`
`30171-0025002/ITI-001
`
`4288
`
`26161
`
`7590
`
`01/18/2017
`
`FISH & RICHARDSON I’.C. (BO)
`PO. BOX 1022
`MINNEAPOLIS, MN 55440—1022
`
`The projected patent number and issue date are specified above.
`
`ISSUE NOTIFICATION
`
`Determination of Patent Term Adjustment under 35 U.S.C. 154 (b)
`(application filed on or after May 29, 2000)
`
`The Patent Term Adjustment is 0 day(s). Any patent to issue from the above-identified application will include
`an indication of the adjustment on the front page.
`
`If a Continued Prosecution Application (CPA) was filed in the above-identified application, the filing date that
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`Retrieval (PAIR) WEB site (http://pair.uspto. gov).
`
`Any questions regarding the Patent Term Extension or Adjustment determination should be directed to the
`Office of Patent Legal Administration at (571)-272-7702. Questions relating to issue and publication fee
`payments should be directed to the Application Assistance Unit (AAU) of the Office of Data Management
`(ODM) at (571)-272-4200.
`
`APPLICANT(S) (Please see PAIR WEB site http://pairllspto gov for additional applicants):
`
`Ionian Technologies, Inc., San Diego, CA;
`Brian K. Maples, Lake Forest, CA;
`Rebecca C. Holmberg, San Diego, CA;
`Andrew P. Miller, San Diego, CA;
`Jarrod Provins, Dana Point, CA;
`Richard Roth, Carlsbad, CA;
`Jeffrey Mandell, San Diego. CA;
`
`The United States represents the largest, most dynamic marketplace in the world and is an unparalleled location
`for business investment, innovation, and commercialization of new technologies. The USA offers tremendous
`resources and advantages for those who invest and manufacture goods here. Through SelectUSA, our nation
`works to encourage and facilitate business investment. To learn more about why the USA is the best country in
`the world to develop technology, manufacture products, and grow your business, visit SelectUSA.gov.
`
`IR103 (Rev. 10/09)
`
`6
`
`

`

`IN THE UNITED STATES PATENT AND TRADEMARK OFFICE
`
`Attorney's Docket No.: 30171-0025002 / ITI-001
`
`First Named Inventor : Brian K. Maples
`Serial No.
`:
`14/067,620
`Filed
`: October 30, 2013
`
`1637
`:
`Art Unit
`: Angela Marie Bertagna
`Examiner
`:
`4288
`Confirmation No.
`Notice of Allowance Date: December 15, 2016
`N ICKIN G AND EXTENSION AMPLIFICATION REACTION FOR
`THE EXPONENTIAL AMPLIFICATION OF NUCLEIC ACIDS
`
`Title
`
`:
`
`MAIL STOP ISSUE FEE
`Commissioner for Patents
`PO. Box 1450
`
`Alexandria, VA 22313-1450
`
`REPLY TO NOTICE OF ALLOWANCE
`
`In response to the Notice of Allowance dated December 15, 2016, enclosed is a
`
`completed Part B — F ee(s) Transmittal.
`
`The issue fee was previously paid on September 21, 2016 and no fee is believed to be
`
`due. However, please apply any necessary charges or credits to Deposit Account 06 1050,
`
`referencing the above attorney docket number.
`
`Respectfully submitted,
`
`/Ian JS. Lodovice Reg. No. 59 749/
`Ian J. Lodovice
`
`Reg. No. 59,749
`
`Date: December 19, 2016
`
`Customer Number 26161
`Fish & Richardson P.C.
`
`Telephone: (6] 7) 956—5972
`Facsimile:
`(877) 769-7945
`
`23598852.doc
`
`7
`
`

`

`Note: A certificate of maiiing can only be used for domestic mailings of the
`Fee(s) Transmittal. This certificate cannot be used for any other accompanying
`papers. Each additional paper, such as an assignment or formal drawing, must
`have its own certificate of mailing or transmission.
`_
`_
`Certificate of Mailing or Transmission
`I hereby certify that this Fee(s) Transmittal is being depos1ted With the Umted
`States Postal Service with sufficient postage for first class mail in an envelope
`addressed to the Mail Stop ISSUE FEE address above, or being facsimile
`
`transmitted to the USPTO (571) 273-2885 on the date indicated below,
`
`(Daposnot's name)
`(Signature)
`(Date)
`
`APPLICATION NO.
`FILING DATE
`FIRST NAMED INVENTO 1
`ATTORNEY DOCKET NO.
`CONFIRMATION NO.
`
`
`
`
`30171-0025002
`Brian K. Maples
`10/30/2013
`14/067,620
`TITLE OF INVENTION: NICKING AND EXTENSION AMP SIFICATION REACTION FOR THE EXPONENTIAL AMPLIFICATION OF NUCLEIC ACIDS
`
`4288
`
`PART B - FEE(S) TRANSMITTAL
`
`Complete and send this form, together with applicable fee(s), to: M_ail Mail Stop ISSUE FEE
`Commissioner for Patents
`P.0. Box 1450
`Alexandria, Virginia 22313-1450
`
`or Fax (571)-273-2885
`INSTRUCTIONS: This form should be used for transnritting the ISSUE FEE and PUBLICATION FEE (if required). Blocks 1 through 5 should be completed where
`appropriate. A11 further correspondence including the Patent, advance orders and notification of maintenance fees will be mailed to the current correspondence address as
`indicated unless corrected below or directed otherwise in Block 1, by (a) specifying a new correspondence address; and/or (b) indicating a separate "FEE ADDRESS“ for
`
`maintenance fee notifications.
`CURRENT CORRESPONDENCE ADDRESS (Notc2Usc Block 1 for any change ofaddrcss)
`
`26161
`
`7590
`
`12/ 15/2016
`
`FISH & RICHARDSON P.C.
`P 0 BOX 1022
`MINNEAPOLIS~ MN 554404022
`
`
`
`
`
`
`
`
`
`
`
`PUBLICATION FEE DUE PREV. PAID ISSUE FEE
`APPLN. TYPE
`ENTITY STATUS
`ISSUE FEE DUE
`TOTAL FEE(S) DU 3
`DATE DUE
`
`
`
`
`nonprovisional
`EXAMlNER
`
`LARGE
`
`$0
`ART UNIT
`
`$0
`CLASS-SUB CLASS
`
`$960.00
`
`$0
`
`03/15/2017
`
`BERTAGNA, ANGELA MARIE
`
`1637
`
`
`43 5-006120
`
`1. Change of correspondence address or indication of "Fee Address" (3 7
`CFR l .3 63 ).
`
`1 Change of correspondence address (or Change of Correspondence
`I
`Address form PTO/SB/l22) attached.
`[
`] "Fee Address" indication (or "Fee Address" Indication form
`PTO/SB/47; Rev 03-02 or more recent) attached. Use of a Customer
`Number is required.
`
`2, For priming on the patent from page, list
`(l) the names of up to 3 registered patent attomeys
`of agerrts OR, alternatively,
`(2) the name of a single firm (having as a member a
`registered attorney or agent) and the names of up to
`2 registered patent attorneys or agents. If no name is
`listed, no name will be printed.
`
`1 Fish & Richardson P.C.
`2
`
`3
`
`3. ASSIGNEE NAME AND RESIDENCE DATA TO BE PRINTED ON THE PATENT (print or type)
`PLEASE NOTE: Unless an assignee is identified below, no assignee data will appear on the patent. If an assignee is identified below, the document has been filed for
`recordation as set forth in 37 CFR 311. Completion of this form is NOT a substitute for filing an assignment.
`
`(B) RESIDENCE: (CITY and STATE OR COUNTRY)
`(A) NAME OF ASSIGNEE
`Ionian Technologies, Inc.
`San Diego, CA
`
`Please check the appropriate assignee category or categories (will not be printed on the patent): [
`] Individual [X] Corporation or other private group entity [
`1 Government
`4a. The following fee(s) are submitted:
`4b. Payment of Fee(s): (Please first reapply any previously paid issue fee shown above)
`[X] Issue Fee
`[
`] A check in the amount of the feet5) is enclosed.
`[
`] Publication Fee (No small entity discount permitted)
`[
`] Payment by credit card. Form PTO-203 8 is attached
`[
`] Advance Order - # of Copies
`[X] The Director is hereby authorized to charge the required fee(s), or credit any overpayment, to
`Deposit Account Number 06-1050
`
`5. Change in Entity Status (from status indicated above)
`[
`] Applicant cemfy‘mg mien) entity status, See 37 CFR 119
`
`[
`
`J Applicant asserting small entity status. See 37 CFR 127‘
`
`NOTE: Absent a valid certification of Micro Entity Status (see form PTO/SB/ 15A and 15B), issue fee
`payment in the micro entity amount will not be accepted at the risk of application abandonment.
`NOTE: Ifthe application was previously under micro entity status. checking this box will be
`taken to be a notification of loss of entitlement to micro entity status.
`NOTE: Checking this box will be taken to be a notification of loss of entitlement to small or
`] Applicant changing to regular undiscounted fee status.
`[
`micro entity status, as applicable.
`The Director of the USPTO is requested to apply the Issue Fee and Publication Fee (if any) or to re-apply any previously paid issue fee to the application identified above.
`NOTE: The Issue Fee and Publication Fee (if required) will not be accepted from anyone other than the applicant; a registered attorney or agent,. or the assignee or other party
`
`in interest as shown by the records of the United States Patent and Trademark Office.
`
`Authorized Signature /Ian J.S. Lodovice. Reg. No. 59,749/
`Date December 19, 2016
`
`1311 J. LOdOVICC
`Registration No.
`59,749
`
`Typed or printed name
`
`23598864doc
`
`8
`
`

`

`IN THE UNITED STATES PATENT AND TRADEMARK OFFICE
`
`Attorney's Docket No.: 30171-0025002 / ITI-001
`
`I637
`:
`Art Unit
`First Named Inventor : Brian K. Maples
`: Angela Marie Bertagna
`Examiner
`Serial No.
`:
`14/067,620
`:
`4288
`Conf. No.
`Filed
`: October 30, 2013
`Title
`: NICKING AND EXTENSION AMPLIFICATION REACTION FOR
`THE EXPONENTIAL AMPLIFICATION OF NUCLEIC ACIDS
`
`Mail Stop Amendment
`Commissioner for Patents
`PO. Box 1450
`
`Alexandria, VA 22313-1450
`
`INTERVIEW SUMNIARY
`
`The undersigned representative thanks the Examiner for the courtesy of the telephonic
`
`interview held on November 29, 2016.
`
`The substance of the interview included a discussion of claims 67, 95, and 107 and the
`
`reference Nelson et a1. During the interview, an agreement was reached on December 1, 2016.
`
`Applicant acknowledges and thanks Examiner Bertagna for the Examiner-Initiated Interview
`
`Summary dated December 15, 2016.
`
`Respectfully submitted,
`
`/Ian IS. Lodovice, Reg. No. 59,749/
`Ian J. Lodovice
`
`Reg. No. 59,749
`
`Date: December 19, 2016
`
`Customer Number 26161
`Fish & Richardson P.C.
`
`Telephone: (617) 956-5972
`Facsimile:
`(877) 769—7945
`23598848.doc
`
`9
`
`

`

`Electronic Acknowledgement Receipt
`
`“—
`
`——
`
`T'tle 0f lnventlon:
`
`Nicking and Extension Amplification Reaction forthe Exponential
`Amplification of Nucleic Acids
`
`
`
`First Named Inventor/Applicant Name:
`
`Brian K. Maples
`
`Customer Number:
`
`26161
`
`Ian J.S. Lodovice/Stacey Hill
`
`Filer Authorized By:
`
`Ian J.S. Lodovice
`
`Attorney Docket Number:
`
`3017170025002 / ITerO1
`
`Receipt Date:
`
`Filing Date:
`
`19—DEC—201 6
`
`30—OCT—201 3
`
`Time Stamp:
`
`14:44:33
`
`
`
`Application Type: Utility under 35 USC 111(a)
`
`Payment information:
`
`Submitted with Payment
`
`E18509
`
`Document
`Number
`
`Document Descri
`
`tion
`
`p
`
`File SizelBytes)I
`Message Digest
`196349
`
`Pages
`Multi
`Part I.zip (if appl.)
`
`Issue Fee Payment (PTO—858)
`
`30171|ssueFee.pdf
`
`9d51:54259[911792d89llbl40090337b27cfi
`
`10
`
`10
`
`

`

`Information:
`
`Applicant summary of interview with
`.
`examiner
`
`301710025002|S.pdf
`
`e5d6e1eel531095332c325kb1788d623de
`35597
`
`
`
`
`New Applications Under 35 U.S.C. 111
`lfa new application is being filed and the application includes the necessary components for a filing date (see 37 CFR
`1.53(b)—(d) and MPEP 506), a Filing Receipt (37 CFR 1.54) will be issued in due course and the date shown on this
`Acknowledgement Receipt will establish the filing date of the application.
`
`National Stage of an International Application under 35 U.S.C. 371
`If a timely submission to enter the national stage of an international application is compliant with the conditions of 35
`U.S.C. 371 and other applicable requirements a Form PCT/DOIEOI903 indicating acceptance of the application as a
`national stage submission under 35 U.S.C. 371 will be issued in addition to the Filing Receipt, in due course.
`
`Warnings:
`Information:
`
`Total Files Size (in bytes)
`
`267703
`
`This Acknowledgement Receipt evidences receipt on the noted date by the USPTO of the indicated documents,
`characterized by the applicant, and including page counts, where applicable. It serves as evidence of receipt similar to a
`Post Card, as described in MPEP 503.
`
`New International Application Filed with the USPTO as a Receiving Office
`lfa new international application is being filed and the international application includes the necessary components for
`an international filing date (see PCT Article 11 and MPEP 1810), a Notification of the International Application Number
`and of the International Filing Date (Form PCT/ROI105) will be issued in due course, subject to prescriptions concerning
`national security, and the date shown on this Acknowledgement Receipt will establish the international filing date of
`the application.
`
`11
`
`11
`
`

`

`Complete and send this form, together with applicable fee(s), to: M_ail Mail Stop ISSUE FEE
`Commissioner for Patents
`PO. Box 1450
`Alexandria, Virginia 22313-1450
`
`or Fax (57l)-273-2885
`INSTRUCTIONS: This form should be used for transmitting the ISSUE FEE and PUBLICATION FEE (if required). Blocks 1
`through 5 should be completed where
`appropriate. All further correspondence including the Patent, advance orders and notification of maintenance fees will be mailed to the crrnent conespondeuce address as
`indicated unless conected below or directed otherwise in Block 1, by (a) specifying a new correspondence address; and/or (b) indicating a separate "FEE ADDRESS" for
`
`maintenance fee notifications.
`CURRENTCOKRESPONDENCE ADDRESS (Note. Us: Black 1 [many change ofaddress)
`Note: A certificate of mailing can only be used for domestic mailings of the
`Fee(s) Transmittal. This certificate cannot be used for any other accompanying
`papers. Each additional paper, such as an assignment or formal drawing, must
`have its own certificate ofmailing or transmission
`Certificate of Mailing or Transmission
`I hereby certify that this Fee(s) Transmittal is being deposited with the United
`States Postal Service with sufficient postage for first class mail in an envelope
`addressed to the Mail Stop ISSUE FEE address above, or being facsimile
`transmitted to the USPTO 571 273-2885 on the date indicated below.
`(Depositor‘s name)
`(Signature)
`
`ARI)
`
`.
`'
`FI H
`50“ P C
`S & RICH
`PO' BOX 1022
`MINNEAPOLIS, MN 55440-1022
`
`,
`
`
`
`
`
`PART B - FEE(S) TRANSMITTAL
`
`fiW/
`
`26161
`
`7590
`
`12/15/2016
`
`
`‘74;
`1,,
`
`DEC 1 9 2MB :0
`4'7
`
`.,
`-
`
`FIRST NAMED INVENTUR
`
`
`
`(Dale)
`
`-
`
`APPLICATION No
`
`FILING DATE
`
`ATTORNEY DOCKET NO.
`
`CONFIRMATION NO.
`
`30171-0025002
`Brian K. Maples
`10/30/2013
`14/067,620
`TITLE OF INVENTION: NICKING AND EXTENSION AMPLIFICATION REACTION FOR THE EXPONENTIAL AMPLIFICATION OF NUCLEIC ACIDS
`
`
`4288
`
`APPLN. TYPE
`
`ENTITY STATUS
`
`ISSUE FEE DUE
`
`PUBLICATION FEE DUE PREV. PAED ISSUE FEE
`
`TOTAL FEE(S) DUE
`
`nonprovisional
`
`LARGE
`
`$0
`
`$0
`
`$960.00
`
`$0
`
`03/15/2017
`
`435-006120
`I637
`BERTAGNA, ANGELA MARIE
`2, For printing on the patent fro n1 page, list
`l. Change of conespondence address or indication of "Fee Address" (37
`CFR 1.363).
`(l) the names of up to 3 registered patent attorneys
`or agents 0R, alternatively,
`
`1 Fish & Richardson P.C.
`
`] Change of conespondence address (or Change of Correspondence
`[
`Address form PTO/SB/ 1'22) attached.
`as a membera
`(2) the name of a single firm (havi
`.
`.
`,,
`,,
`,,
`.
`.
`.
`,,
`registered attorney or agent) and tllrlegnames of up to
`] Fee Address indication (or Fee Address Indication form
`l
`2 registered patent attorneys or agents. If no name is
`PTO/SB/47; Rev 03-02 or more recent) attached. Use of a Customer
`listed, no name will be printed.
`Number '5 required.
`3. ASSIGNEE NAME AND RESIDENCE DATA TO BE PRINTED ON THE PATENT (print or type)
`
`2
`
`3
`
`.
`
`PLEASE NOTE: Unless an assignee is identified below, no assignee data will appear on the patent. If an nssignee is identified below, the document has been filed for
`recordation as setforth in 37 CFR 3.11. Completion of this form is NOT a substitute for filing an assignment.
`(A) NAME OF ASSIGNEE
`(B) RESIDENCE: (CITY and STATE OR COUNTRY)
`Ionian Technologies, Inc.
`San Diego, CA
`
`] Govemment
`] Individual [X] Corporation or other private group entity [
`Please check the appropriate assignee category or categories (will notbe printed on the patent): [
`4a. The following fee(s) are submitted:
`4b. Paymentof Fee(s): (Please first reapply any previously paid issue fee shown above)
`[X] Issue Fee
`[
`] A check inthe amount ofthe fee(s) is enclosed.
`[
`] Publication Fee (No small entity discount permitted)
`[
`| Payment by credit card. Forrn PTO-2038 is attached
`[
`] Advance Order - it of Copies
`[X] The Director is hereby authorized to charge the required fee(s), or credit any overpayment, to
`Deposit Account Number 06-1050
`5. Change in Entity Status (from status indicated above)
`.
`[
`] Applicant certifying micro entity status. 55¢ 37 CFR [.29
`NOTE: Absent a valid certification of Micro Entity Status (sec form PTO/SB/ISA and 15B), issue fee
`payment in the micro cntity amount will not be accepted at the risk of application abandonment.
`] Applicant asserting small entity status. See 37 CFR 127. m: Il‘tlie application was previously under micro entity status, checking this box will be
`taken to be a notification of loss of entitlement to micro entity slams.
`
`[
`
`[
`
`] Applicant changing to regular undiscounted fee status. my Checking this box will be taken to be a notification of loss of entitlement to small or
`
`micro entity status, as applicable.
`The Director of the USPTO is requested to apply the lssrre Fee and Publication Fee (ifany) orto re-apply any previously paid issue fee to the application identified above.
`NOTE: The Issue Fee and Publication Fee (if required) will not be accepted from anyone other titan the applicant; a registered attomey or agent; or the assignee or other party
`
`in interest as shown by the records of the United States Patent and Trademark Office.
`
`Authorized Signature /lan J.S. Lodovicea Reg. No. 59,749/
`'
`Date December 19E 2016
`Ian J. LOdOViCCTyped or primed name 592749 Registration No.
`
`
`
`
`
`
`
`235
`
`8,54. oc
`Jus lent date: 12/21/2315 5311251112
`89/22/20161NTEFSU 33335299 351353
`31 FC:1581
`968.88 ca
`
`14867620
`
`RUDE 80088003 861858
`968.88 Di)
`
`10067620
`
`12/31/2316 SDI
`mm
`'
`
`5‘
`
`12
`
`12
`
`

`

`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`
`
`UNITED STATES DEPARTMENT OF CONEVIERCE
`United States Patent and Trademark Office
`Addiess: COMSIISSIONER FOR PATENTS
`P.O. Box 1450
`Alexandria. Virginia 2231371430
`www.uspto.gov
`
`NOTICE OF ALLOWANCE AND FEE(S) DUE
`
`26161
`
`7590
`
`_
`12/13/2016
`
`FISH & RICHARDSON PC. (BO)
`PO. BOX 1022
`MINNEAPOLIswss440-1022
`
`EXAMINER
`
`BERTAGNA, ANGELA MARIE
`
`1637
`
`DATE MAILED: 12/15/2016
`
`APPLICATION NO.
`
`FILING DATE
`
`FIRST NAIVIED INVENTOR
`
`ATTORNEY DOCKET NO.
`
`CONFIRMATION NO.
`
`30171—0025002 / ITI-001
`Brian K. Maples
`10/30/2013
`14/067,620
`TITLE OF INVENTION: Nicking and Extension Amplification Reaction for the Exponential Amplification of Nucleic Acids
`
`4288
`
`APPIN TYPE
`ENTITY STATIIS
`ISSI IF FEE DIIE
`PIIBI IC ATION FEE DIIE
`PREV. PAID ISSITE FEE
`TOTAI FEE(S) DIIE
`DATE DIIE
`
`nonprovisional
`UNDISCOUN TED
`$960
`$960
`03/15/2017
`
`THE APPLICATION IDENTIFIED ABOVE HAS BEEN EXAMINED AND IS ALLOWED FOR ISSUANCE AS A PATENT.
`PROSECUTION ON TIIE MERITS IS CLOSED. TIIIS NOTICE OF ALLOWANCE IS NOT A GRANT OF PATENT RIGIITS.
`THIS APPLICATION IS SUBJECT TO WITHDRAVVAL FROM ISSUE AT THE INITIATIVE OF THE OFFICE OR UPON
`PETITION BY THE APPLICANT. SEE 37 CFR 1.313 AND MPEP 1308.
`
`THE ISSUE FEE AND PUBLICATION FEE (IF REQUIRED) MUST BE PAID WITHIN TI-IREE MONTI-IS FROM THE
`MAILING DATE OF THIS NOTICE OR THIS APPLICATION SHALL BE REGARDED AS ABANDONED.
`THIS
`STATUTORY PERIOD CANNOT BE EXTENDED.
`SEE 35 U.S.C. 151. THE ISSUE FEE DUE INDICATED ABOVE DOES
`NOT REFLECT A CREDIT FOR ANY PREVIOUSLY PAID ISSUE FEE IN THIS APPLICATION.
`IF AN ISSUE FEE HAS
`PREVIOUSLY BEEN PAID IN THIS APPLICATION (AS SHOWN ABOVE), THE RETURN OF PART B OF THIS FORIVI
`WILL BE CONSIDERED A REQUEST TO REAPPLY THE PREVIOUSLY PAID ISSUE FEE TOWARD THE ISSUE FEE NOW
`DUE.
`
`HOW TO REPLY TO THIS NOTICE:
`
`I. Review the ENTITY STATUS shown above. If the ENTITY STATUS1S shown as SMALL or MICRO verify whether entitlement to that
`entity status still applies.
`
`If the ENTITY STATUSIs the same as shown above, pay the TOTAL FEE(S) DUE shown above.
`
`If the ENTITY STATUS is changed from that shown above, on PART B - FEE(S) TRANSMITTAL, complete section number 5 titled
`"Change in Entity Status (from status indicated above)".
`
`For purposes of this notice, small entity fees are 1/2 the amount of undiscounted fees, and micro entity fees are 1/2 the amount of small entity
`fees.
`
`II. PART B - FEE(S) TRANSMITTAL, or its equivalent, must be completed and returned to the United States Patent and Trademark Office
`(USPTO) with your ISSUE FEE and PUBLICATION FEE (if required). If you are charging the fee(s) to your deposit account, section "4b"
`of Part B - Fee(s) Transmittal should be completed and an extra copy of the form should be submitted. If an equivalent of Part B is filed, a
`request to reapply a previously paid issue fee must be clearly made, and delays in processing may occur due to the difficulty in recognizing
`the paper as an equivalent of Part B.
`
`III. All communications regarding this application must give the application number. Please direct all communications prior to issuance to
`Mail Stop ISSUE FEE unless advised to the contrary.
`
`IMPORTANT REMINDER: Utility patents issuing on applications filed on or after Dec. 12, 1980 may require payment of
`maintenance fees. It is patentee's responsibility to ensure timely payment of maintenance fees when due.
`
`PTOL—SS (Rev. 02/11)
`
`Page 1 of 3
`
`13
`
`13
`
`

`

`PART B - FEE(S) TRANSMITTAL
`
`Complete and send this form, together with applicable fee(s), to: M_ail Mail Stop ISSUE FEE
`Commissioner for Patents
`P.0. Box 1450
`Alexandria, Virginia 22313-1450
`or m (571 )-273-2885
`through 5 should be completed where
`INSTRUCIIONS: This form should be used for transmitting the ISSUE FEE and PUBLICATION FEE (if required). Blocks 1
`propriate. All further correspondence including the Patent advance orders and notification of maintenance fees will be mailed to the current correspondence address as
`incated unless corrected below or directed otherwise in Block 1 by (a) specifying a new correspondence address; and/or (b) indicating a separate "FEE ADDRESS" for
`maintenance fee notifications.
`
`CURRENT CORRESPONDENCE ADDRESS (Note: Uh: Block HUI any chime: of minim»)
`
`12/15/7016
`7590
`75161
`“
`“
`“
`FISH & RICHARDSON P.C. (BO)
`P 0 BOX 1022
`'
`'
`MINNEAPOLIS’WWO'W
`
`Note: A certificate of mailin can only be used for domestic mailings of the
`Fee(s) Transmittal. This certi icate cannot be used for any other accompanying
`apers. Each additional paper such as an assignment or formal drawing, must
`Eave its own certificate of mailing or transmission.
`
`Certificate of Mailing or Transmission
`I hereby certify that this Fee(s) Transmittal is being deposited with the Lnited
`States Postal Service with sufficient postage for first class mail in an envelope
`addressed to the Mail Stop ISSUE FEE address above, or being facsimile
`transmitted to the USPTO (571) 273—2885, on the date indicated below.
`epositor's name
`
`
`
`APPLICATION 1\O.
`FILING DATE
`FIRST NMIED INVENTOR
`ATTORNEY DOCKET NO.
`CONFIRMATION NO.
`
`14/067.620
`10/30/2013
`Brian K. Maples
`3017170025002 / ITIAOOI
`4288
`TITLE OF INVENTION: Nicking and Extension Amplification Reaction for the Exponential Amplification of Nucleic Acids
`
`
`PREV. PA ) ISSI E FFF
`
`
`APPLN TYPE
`
`ENTITY STATUS
`
`ISSUE FEE DUE
`
`PUBLICATION FEE DUE
`
`nonprovisiona]
`
`UNDISCOUNTFD
`
`TOTAL FEE(S) DUE
`
`$960
`
`DATE DUE
`
`03/15/2017
`
`EXAMINER
`
`ART UNIT
`
`CLASS-SUB CLASS
`
`BERTAGNA, ANGELA MARIE
`
`1637
`
`43 5-006120
`
`2. For printing on the patent front page, list
`1. Change of correspondence address or indication of "Fee Address" (37
`CF 1 1.363).
`(1) The names of up to 3 registered patent attorneys
`or agents OR alternatively.
`3 Chan e of correspondence address (or Change of Correspondence
`Addressoorm PTO/SB/122) attached.
`(2) The name of a single firm (having as a member a
`registered attorney or agent) and the names of 11p to
`3 ”Fee Address" indication (or ”Fee Address" Indication form
`2 registered patent attorneys or agents. If no name is
`)TO/SB/47; Rev 03—02 or more recent) attached. Use of a Customer
`listed no name will be printed
`Number is required.
`3. ASSIGNEj I\AV1E AND RESIDENCE DATA TO BE PRINTED ON THE PATENT (print or type)
`If an assignee is identified below. the document has been filed for
`)LEASE NOTE: Unless an assignee is identified below. no assignee data will appear on the patent.
`recordation as set forth in 37 CFR 3.11. Completion of this form is NOT a substitute for filing an assignment.
`(A) NAMj OF ASSIGNEE
`(B) RESIDENCE: (CITY and S TATE OR COUNTRY)
`
`
`
`
`
`
`
`2
`w
`
`Please check the appropriate assignee category or categories (will not be printed on the patent) : D Individual D Corporation or other private group entity D Government
`
`4a. The following fee(s) are submitted:
`3 Issue Fee
`3 Publication Fee (No small entity discount permitted)
`3 Advance Order , # of Copies
`
`5. Change in Entity Status (from status indicated above)
`3 Applicant certifying micro entity status. See 37 CFR 1.29
`
`3 Applicant asserting small entity status. See 37 CFR 1.27
`
`3 Applicant changing to regular undiscounted fee status.
`
`
`
`4b. Payment of Fee(s): (Please first reapply any previously paid issue fee shown above)
`3 A check is enclosed.
`3 Payment by credit card. Form PTO—2038 is attached.
`jThe director is hereby authorized to charge the required fee(s), any deficiency, or credits any
`overpayment, to Deposit Account Number
`(enclose an extra copy of this form).
`
`
`
`NOTE: Absent a valid certification of Micro Entity Status (see forms PTO/SB/ 15A and 15B), issue
`fee payment in the micro entity amount will not be accepted at the risk of application abandonment.
`NOTE: If the application was previously under micro entity status, checking this box will be taken
`to be a notification of loss of entitlement to micro entity status.
`NOTE: Checking this box will be taken to be a notification of loss of entitlement to small or micro
`entity status. as applicable.
`
`NOTE: This form must be signed in accordance with 37 CFR 131 and 1.33. See 37 CFR 1.4 for signature requirements and certifications.
`
`Authorized Signature
`
`Typed or printed name
`
`
`Date
`
`Registration No.
`
`PTOL-85 Part B (IO-l3) Approved for use through 10/31/2013.
`
`OMB 0651-0033
`
`US. Patent and Trademark Office; US. DEPARTMENT OF COMMERCE
`
`Page 2 of 3
`
`14
`
`14
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`

`

`UNITED STATES PATENT AND TRADEMARK OFFICE
`
`
`
`UNITED STATES DEPARTMENT OF CONEVIERCE
`United States Patent and Trademark Office
`Addiess: COME/IISSION'ER FOR PATENTS
`P.O. Box 1450
`Alexandria. Virginia 2231371430
`www.mspto.gov
`
`APPLICATION NO.
`FILING DATE
`FIRST NAIVIED INV