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`Mansoor A. Khan, R.Ph., Ph.D.
`Professor & Vice Dean
`Director, Formulations Design and Development Core Laboratory
`Irma Lerma Rangel College of Pharmacy | Texas A&M Health Science Center
`Reynolds Medical Building, Suite 159 | College Station, Texas 77843-1114
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`PERSONAL INFORMATION
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`US Citizen
`Wife - Rehana; Three children
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`EMPLOYMENT
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`Texas A&M Health Science Center – College of Pharmacy, College Station, TX:
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`Sept 2015 to present
`Professor and Vice Dean – Director of Formulations Design and Development Core
`Laboratories
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`Food and Drug Administration, Center for Dug Evaluation and Research, Maryland
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`May 2004 to Sept 2015
`Director, Division of Product Quality Research,
`SBRS Scientist, August 2005 to Sept 2015
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`Texas Tech University Health Sciences Center, School of Pharmacy:
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`September 2000 to May 2004
`Professor of Pharmaceutics (Tenured) and Director of Graduate Program
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`August 1998 to August 2000
`Associate Professor of Pharmaceutics and Director of Graduate Program
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`University of Louisiana at Monroe
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`July 1996 to July 1998
`Associate Professor of Pharmaceutics (Tenured)
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`June 1992 to June 1996
`Assistant Professor of Pharmaceutics
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`Novartis Pharmaceuticals Inc., New Jersey;
`Pharmaceutical R & D
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`May 1991- August 1991
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`PSG2002
`Catalent Pharma Solutions v. Patheon Softgels
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`Mansoor A. Khan Page 2
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`St. John's University, New York; September 1987- May 1992
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`Teaching and Research Fellow in Pharmaceutics
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`Biological Evans Pharmaceutical Company; Sept 1985- July 1986
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`Research and Development Scientist
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`EDUCATION
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`Ph.D. in Pharmaceutics (focus on industrial pharmacy and biopharmaceutics), May
`1992, St. John's University, College of Pharmacy and Allied Health Professions, New
`York.
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`Dissertation: Product and Process Optimization, and Bioavailability Evaluation of
`Controlled Release Ibuprofen:Eudragit Coprecipitates in Normal Human Volunteers
`(Major Advisor: Prof. Sanford Bolton)
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`M.S. in Pharmaceutics (focus on physical pharmacy and drug delivery systems),
`January 1988, Idaho State University, Idaho.
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`M.S. in Pharmaceutical Technology, June 1984, Andhra University, India
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`B.S. in Pharmacy, July 1982, Kakatiya University, India.
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`PROFESSIONAL LICENSURE
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`Registered Pharmacist. NY State Lic. # 44017 - Active
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`SEMESTER-LONG COURSES TAUGHT
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`Advanced Pharmaceutics, Industrial Pharmacy (Manufacturing Science), Product
`Formulation, Biopharmaceutics, Pharmacokinetics, and Drug Stability to MS and Ph.D.
`students.
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`Biopharmaceuitcs/Pharmacokinetics, Pharmaceutical and Clinical Calculations,
`Pharmaceutics (1, 2, and 3), and Pharmaceutics and Compounding Laboratories to
`Pharm.D. students.
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`PEER-REVIEWED MANUSCRIPTS (*indicates corresponding author)
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`1. Kislalioglu, M. S., Khan, M. A., Blount, C., Goettsch, R. W., & Bolton, S. (1991).
`Physical characterization and dissolution properties of ibuprofen: Eudragit
`coprecipitates. Journal of pharmaceutical sciences, 80(8), 799-804.
`2. Tammara, V. K., Narurkar, M. M., Crider, A. M., & Khan, M. A. (1993). Synthesis
`and evaluation of morpholinoalkyl ester prodrugs of indomethacin and naproxen.
`Pharmaceutical research, 10(8), 1191-1199.
`3. Tammara, V. K., Narurkar, M. M., Crider, A. M., & Khan, M. A. (1994).
`Morpholinoalkyl ester prodrugs of diclofenac: synthesis, in vitro and in vivo
`evaluation. Journal of pharmaceutical sciences, 83(5), 644-648.
`4. Khan, M. A., Bolton, S., & Kislalioglu, M. S. (1994). Optimization of process
`variables for the preparation of ibuprofen coprecipitates with Eudragit S100.
`International journal of pharmaceutics, 102(1), 185-192.
`5. Singh, S.K, Karnachi, A.A., Durani, M.J., Dodge, J., and Khan, M.A.* (1995).
`Application of a Novel Latex on Ibuprofen Pellets. Control Rel. Bioact. Mater.22.
`6. Karnachi, A.A., Singh, S.K, Sastry, S.V., Reddy, I.K., and Khan, M.A.*(1995).
`Characterization and In Vivo Ulcerogenecity Study of Oral Extended Release
`Preparations. Control Rel. Bioact. Mater., 22, pp. 1135-1136.
`7. Karnachi, A.A., DeHon, R.A. and Khan, M.A.* (1995). Plackett-Burman Screening
`of Coprecipitates with Polymer Mixtures for Controlled Drug Delivery. Die
`Pharmazie, 50, pp. 550-553.
`8. Karnachi, A.A., DeHon, R.A. and Khan, M.A.*(1995). Compression of
`Indomethacin Coprecipitates with Polymer Mixtures; Effect of Preparation
`Methodology. Drug Dev. Ind. Pharm., 21(12), pp. 1473-1483.
`9. Singh, S. K., Dodge, J., Durrani, M. J., & Khan, M. A. * (1995). Optimization and
`characterization of controlled release pellets coated with an experimental latex: I.
`Anionic drug. International journal of pharmaceutics, 125(2), 243-255.
`10. Khan, M. A. *, Karnachi, A. A., Singh, S. K., Sastry, S. V., Kislalioglu, S. M., &
`Bolton, S. (1995). Controlled release coprecipitates: formulation considerations.
`Journal of controlled release, 37(1), 131-141.
`11. Karnachi, A. A., & Khan, M. A. * (1996). Box-Behnken design for the optimization
`of formulation variables of indomethacin coprecipitates with polymer mixtures.
`International journal of Pharmaceutics, 131(1), 9-17.
`12. Singh, S. K., Durrani, M. J., Reddy, I. K., & Khan, M. A. * (1996). Effect of
`permeation enhancers on the release of ketoprofen through transdermal drug delivery
`systems. Die Pharmazie, 51(10), 741-744.
`13. Singh, S. K., Reddy, I. K., & Khan, M. A.* (1996). Optimization and
`characterization of controlled release pellets coated with an experimental latex: II.
`Cationic drug. International journal of pharmaceutics, 141(1), 179-195.
`14. Sastry, S.V., Karnachi, A.A., Durrani, M.J., Reddy, I.K., and Khan, M.A.* (1996).
`Carbopol Polymers in Osmotically Controlled Drug Delivery of Atenolol: Influence
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`of Formulation Variables on Drug Release. Control. Rel. Bioac. Mater., 23, pp.20-
`21.
`15. Sastry, S.V., Reddy, I.K., and Khan, M.A.* (1996). Atenolol Gastrointestinal
`Therapeutic System: Effect of Surface Area, Curing Temperature, and pH on In-Vitro
`Dissolution Profiles. Control. Rel. Bioac. Mater., 23, pp. 115-116.
`16. Reddy, I.K., and Khan, M.A. (1996). Responsive Drug Delivery. US Pharmacist, 21,
`pp. 72-78.
`17. Singh, S. K., Roane, D. S., Reddy, L. K., Durrani, M. J., & Khan, M. A. * (1996).
`Effect of additives on the diffusion of ketoprofen through human skin. Drug
`development and industrial pharmacy, 22(5), 471-474.
`18. Reddy, I. K., Khan, M. A., Wu, W. M., & Bodor, N. S. (1996). Permeability of a soft
`steroid, loteprednol etabonate, through an excised rabbit cornea. Journal of ocular
`pharmacology and therapeutics, 12(2), 159-167.
`19. Khan, M. A., Dib, J., & Reddy, L. K. (1996). Statistical optimization of ketoprofen-
`Eudragit® S100 coprecipitates to obtain controlled-release tablets. Drug development
`and industrial pharmacy, 22(2), 135-141.
`20. Reddy.I.K. and Khan, M.A. (1997). Glaucoma: Etiology, Symptoms and Clinical
`Management. Pharmacy Times, 5, pp. 82-92.
`21. Naidu, S. V., Sastry, S. V., Maxie, C. S., & Khan, M. A. (1997). Effect of plasticizer
`on free volume and permeability in cellulose acetate pseudolatex membranes studied
`by positron annihilation and tracer diffusion methods. Materials Science Forum,
`Vol. 255, pp. 333-335.
`22. Sastry, S. V., Degennaro, M. D., Reddy, L. K., & Khan, M. A. *(1997). Atenolol
`gastrointestinal therapeutic system. I. Screening of formulation variables. Drug
`development and industrial pharmacy, 23(2), 157-165.
`23. Singh, S. K., & Khan, M. A.*(1997). Ibuprofen release from beads coated with an
`experimental latex: Effect of certain variables. Drug development and industrial
`pharmacy, 23(2), 145-155.
`24. Karnachi, A.A, Reddy, I.K., Degennaro, M., & Khan, M.A.*(1997). Comparative
`evaluation of the severity of gastric ulceration by solid dispersions and coprecipitates
`of indomethacin. Journal of drug targeting, 4(5), 297-301.
`25. Sastry, S. V., Reddy, I. K., & Khan, M. A. * (1997). Atenolol gastrointestinal
`therapeutic system: optimization of formulation variables using response surface
`methodology. Journal of controlled release, 45(2), 121-130.
`26. Khan, M.A.* and Reddy, I.K. (1997). Controlled Drug Delivery: Use of Acrylate
`Polymers in Solid Oral Dosage Forms. S.T.P. Pharma. Sci., 7(6), 483-490.
`27. Kunta, J. R., Goskonda, V. R., Brotherton, H. O., Khan, M. A., & Reddy, I. K.
`(1997). Effect of menthol and related terpenes on the percutaneous absorption of
`propranolol across excised hairless mouse skin. Journal of pharmaceutical sciences,
`86(12), 1369-1373.
`28. Reddy, I.K., Stasinos, M., and Khan, M.A. (1998). Arthritis: Etiology, Symptoms,
`and Clinical Management. Drug Store News, Sept, 27-31.
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`29. Kommuru, T. R., Khan, M. A., & Reddy, I. K. (1998). Racemate and enantiomers of
`ketoprofen: phase diagram, thermodynamic studies, skin permeability, and use of
`chiral permeation enhancers. Journal of pharmaceutical sciences, 87(7), 833-840.
`30. Zahir, A., Kunta, J. R., Khan, M. A., & Redely, I. K. (1998). Effect of menthol on
`permeability of an optically active and racemic propranolol across guinea pig skin.
`Drug development and industrial pharmacy, 24(9), 875-878.
`31. Reddy, I.K., Toedter, N.M., and Khan, M.A.(1998). Therapy for Dry Eye. US
`Pharmacist., 23(1), 38-56.
`32. Reddy, I.K. and Khan, M.A.(1998). Fundamentals of Fluid, Electrolyte, and Acid-
`Base Balance. Louisiana Pharmacist, 57(1), 11-15.
`33. Goskonda, V. R., Reddy, I. K., Durrani, M. J., Wilber, W., & Khan, M. A.* (1998).
`Solid-state stability assessment of controlled release tablets containing Carbopol®
`971P. Journal of controlled release, 54(1), 87-93.
`34. Sastry, S. V., & Khan, M. A.*(1998). Aqueous-based polymeric dispersion: face-
`centered cubic design for the development of atenolol gastrointestinal therapeutic
`system. Pharmaceutical development and technology, 3(4), 423-432.
`35. Sastry, S. V., & Khan, M. A. *(1998). Aqueous based polymeric dispersion:
`Plackett–Burman design for screening of formulation variables of atenolol
`gastrointestinal therapeutic system. Pharmaceutica Acta Helvetiae, 73(2), 105-112.
`36. Sastry, S. V., Wilber, W., Reddy, I. K., & Khan, M. A.* (1998). Aqueous-based
`polymeric dispersion: preparation and characterization of cellulose acetate
`pseudolatex. International journal of pharmaceutics, 165(2), 175-189.
`37. Kommuru, T. R., Khan, M. A., Ashraf, M., Kattenacker, R., & Reddy, I. K. (1998).
`A simplified chromatographic method for quantitative determination of Coenzyme Q
`10 in dog plasma. Journal of pharmaceutical and biomedical analysis, 16(6), 1037-
`1040.
`38. Reddy, I.K., B. Ross, W.H., Khan,M.A..(1999). “Diabetes Mellitus: Symptoms,
`Complications, and Clinical Management,” Drug Store News, p22-26.
`39. Kommuru, T.R., Khan, M.A., and I. Reddy, I.K. (1999). “Powder Patterns of
`Enantiomers and Racemate of Ketoprofen,” Powder Diffraction File, 87:833.
`40. Ross, W. H., Lawrence, L. W., Reddy, I. K., Dick, R. M., Roane, D. S., Schulte, M.
`K., Khan, M.A., Olivier, K.J., & Sponberg, L. A. (1999). Implementation of a new
`course with a focus on active learning through integrated curricular approach:
`Pharmacy Care Laboratory I. Journal of Pharmacy Teaching, 7(2), 15-34.
`41. Kommuru, T. R., Ashraf, M., Khan, M. A., & REDDY, I. K. (1999). Stability and
`bioequivalence studies of two marketed formulations of coenzyme Q10 in beagle
`dogs. Chemical and pharmaceutical bulletin, 47(7), 1024-1028.
`42. Khan, M.A.*, Agarwal, V., Vaithiyalingam, S.R., Nazzal, S., Reddy, I.K., and
`Sastry, S.V. (1999). Osmotically-Controlled Oral Dosage Form of a Dipeptide:
`Screening of Formulation Variables. Control. Rel. Bioac. Mater., 26, 980-981.
`43. Khan, M.A.*, Vaithiyalingam, S.R., Agarwal, V., Nazzal, S., Reddy, I.K., and
`Sastry, S.V. (1999). Effect of Temperature and Humidity on Long Term Storage of
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`Atenolol Gastrointestinal Therapeutic System. Control. Rel. Bioac. Mater., 26, 982-
`983).
`44. Goskonda, V. R., Khan, M. A., Hutak, C. M., & Reddy, I. K. (1999). Permeability
`characteristics of novel mydriatic agents using an in vitro cell culture model that
`utilizes SIRC rabbit corneal cells. Journal of pharmaceutical sciences, 88(2), 180-
`184.
`45. Goskonda, V. R., Khan, M. A., Bodor, N. S., & Reddy, I. K. (1999). Chemical
`delivery systems: Evaluation of physicochemical properties and enzymatic stability
`of phenylephrone derivatives. Pharmaceutical development and technology, 4(2),
`189-198.
`46. Kommuru, T. R., Khan, M. A., & Reddy, I. K. (1999). Effect of chiral enhancers on
`the permeability of optically active and racemic metoprolol across hairless mouse
`skin. Chirality, 11(7), 536-540.
`47. Agarwal, V., Singh, S. K., Reddy, I. K., Durrani, M. J., & Khan, M. A.*(1999).
`Cataplasm-based controlled drug delivery: development and optimization of a novel
`formulation. Drug development and industrial pharmacy, 25(5), 659-665.
`48. Shojaei, A. H., Khan, M.A., Lim, G., & Khosravan, R. (1999). Transbuccal
`permeation of a nucleoside analog, dideoxycytidine: effects of menthol as a
`permeation enhancer. International journal of pharmaceutics, 192(2), 139-146.
`49. Khan, M. A.*, Shojaei, A. H., Karnachi, A. A., & Reddy, I. K. (1999). Comparative
`evaluation of controlled-release solid oral dosage forms prepared with solid
`dispersions and coprecipitates. Pharmaceutical technology, 23(5), 58-74.
`50. Goskonda, V. R., Hill, R. A., Khan, M. A., & Reddy, I. K. (2000). Permeability of
`chemical delivery systems across rabbit corneal (SIRC) cell line and isolated corneas:
`a comparative study. Pharmaceutical development and technology, 5(3), 409-416.
`51. Reddy, I.K., Kommuru, T. R., Zaghloul, A. A. A., & Khan, M. A. (2000). Chirality
`and its implications in transdermal drug development. Critical Reviews™ in
`Therapeutic Drug Carrier Systems, 17(4), 285-325.
`52. Vaithiyalingam, S., Zaghloul, A. A., Reddy, I. K., & Khan, M. A. *(2000). Artificial
`neural network and simplex optimization for mixing of aqueous-coated beads to
`obtain controlled-release formulations. Pharmaceutical technology,24(6), 60-72.
`53. Agarwal, V., Reddy, I. K., & Khan, M. A.* (2000). Oral Delivery of Proteins: Effect
`of Chicken and Duck Ovomucoid on the Stability of Insulin in the Presence of
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`α(cid:486)Chymotrypsin and Trypsin. Pharmacy and Pharmacology Communications, 6(5),
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`223-227.
`54. Khan, M. A.*, Karnachi, A. A., Agarwal, V., Vaithiyalingam, S. R., Nazzal, S., &
`Reddy, I. K. (2000). Stability characterization of controlled release coprecipitates and
`solid dispersions. Journal of controlled release, 63(1), 1-6.
`55. Khan, M. A.*, Sastry, S. V., Vaithiyalingam, S. R., Agarwal, V., Nazzal, S., &
`Reddy, I. K. (2000). Captopril gastrointestinal therapeutic system coated with
`cellulose acetate pseudolatex: evaluation of main effects of several formulation
`variables. International journal of pharmaceutics, 193(2), 147-156.
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`56. Nazzal, S., Zaghloul, A. A., Reddy, I. K., & Khan, M. A.* (2001). Analysis of
`ubidecarenone (CoQ10) aqueous samples using reversed phase liquid
`chromatography. Die Pharmazie, 56(5), 394-396.
`57. Reddy, N., Khan, M.A. (2000). “Type II Diabetes: Oral Medications and Clinical
`Management, Drug Store News, October.
`58. Reddy, I. K., Vaithiyalingam, S. R., Khan, M. A., & Bodor, N. S. (2001). Intraocular
`pressure-lowering activity and in vivo disposition of dipivalyl terbutalone in rabbits.
`Drug development and industrial pharmacy, 27(2), 137-141.
`59. Vaithiyalingam, S. R., Sastry, S. V., Dehon, R. H., Reddy, I. K., & Khan, M. A.*
`(2001). Long-term stability characterization of a controlled release gastrointestinal
`therapeutic system coated with a cellulose acetate pseudolatex. Die Pharmazie, 56(1),
`66-69.
`60. Zaghloul, A. A., El-Shattawy, H. H., Kassem, A. A., Ibrahim, E. A., Reddy, I. K., &
`Khan, M. A.* (2001). Honey, a prospective antibiotic: extraction, formulation, and
`stability. Die Pharmazie, 56(8), 643-647.
`61. Nazzal, S., Guven, N., Reddy, I. K., & Khan, M. A.* (2002). Preparation and
`characterization of Coenzyme Q10–Eudragit® solid dispersion. Drug development
`and industrial pharmacy, 28(1), 49-57.
`62. Zaghloul, A. A., Vaithiyalingam, S. R., Faltinek, J., Reddy, I. K., & Khan, M. A.*
`(2001). Response surface methodology to obtain naproxen controlled release tablets
`from its microspheres with Eudragit L100-55. Journal of microencapsulation, 18(5),
`651-662.
`63. Vaithiyalingam, S. R., Tuliani, P., Wilber, W., Reddy, I. K., & Khan, M. A.*(2002).
`Formulation and stability evaluation of Ketoprofen sustained-release tablets prepared
`by fluid bed granulation with Carbopol® 971P Solution. Drug development and
`industrial pharmacy, 28(10), 1231-1240.
`64. Vaithiyalingam, S., Reddy, I. K., Khan, M. A.*, & Guven, N. (2001). Aqueous-
`based cellulose acetate butyrate dispersion: Screening of process and formulation
`variables to obtain verapamil HCl-controlled release beads. Particulate science and
`technology, 19(2), 131-144.
`65. Nazzal, S., Guven, N., Reddy, I. K., & Khan, M. A.*(2002). Preparation and
`characterization of Coenzyme Q10–Eudragit® solid dispersion. Drug development
`and industrial pharmacy, 28(1), 49-57.
`66. Khan, M.A.*, Rambur, S, and Vaithiyalingam, S. (2001). Surface Roughness
`Characterization in Formulation Development. Control Rel. Bioac. Mat.,3008.
`67. Zaghloul, A.A., Nazzal, S, Reddy, I.K., and Khan, M.A.*(2001). Optimization and
`Characterization of Controlled Release Naproxen Microspheres and Tablets, Control
`Rel. Bioac. Mat., 6111.
`68. Kommuru, T. R., Gurley, B., Khan, M. A., & Reddy, I. K. (2001). Self-emulsifying
`drug delivery systems (SEDDS) of coenzyme Q 10: formulation development and
`bioavailability assessment. International journal of pharmaceutics, 212(2), 233-246.
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`vitro stability, and ocular hypotensive activity of t(cid:486)butalone chemical delivery
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`69. Reddy, I. K., Vaithiyalingam, S. R., Khan, M. A., & Bodor, N. S. (2001). Design, in
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`systems. Journal of pharmaceutical sciences, 90(8), 1026-1033.
`70. Zaghloul, A. A., Faltinek, J., Vaithiyalingam, S. R., Reddy, I. K., & Khan, M. A.*
`(2001). Naproxen-Eudragit microspheres: screening of process and formulation
`variables for the preparation of extended release tablets. Pharmazie, 56(4), 321-324.
`71. Vaithiyalingam, S. R., Agarwal, V., Reddy, I. K., Ashraf, M., & Khan, M. A.*
`(2001). Formulation development and stability evaluation of a multicomponent
`nutritional supplement. Pharmaceutical technology, 25(4), 38-48.
`72. Vaithiyalingam, S.R., and Khan, M.A.* (2001). Preparation and Characterization of
`Cellulose Acetate Butyrate Pseudolatex for Multi-Particulate Controlled Drug
`Delivery, Control Rel. Bioac. Mat.,4439.
`73. Vaithiyalingam, S.R., Reddy, I.K., and Khan, M.A.*(2001). Artificial Neural
`Network (ANN) in the Modeling and Optimization of Controlled Release Beads
`Coated with a Cellulose Acetate Butyrate Aqueous Dispersion. Control Rel. Bioac.
`Mat., 5136.
`74. Lockman, P. R., Mumper, R. J., Khan, M. A., & Allen, D. D. (2002). Nanoparticle
`technology for drug delivery across the blood-brain barrier. Drug development and
`industrial pharmacy, 28(1), 1-13
`75. Nazzal, S., Zaghloul, A. A., & Khan, M. A.* (2002). Effect of extragranular
`microcrystalline cellulose on compaction, surface roughness, and in vitro dissolution
`of a self-nanoemulsified solid dosage form of ubiquinone. Pharmaceutical
`technology, 26(4), 86-98.
`76. Vaithiyalingam, S., & Khan, M. A.* (2002). Optimization and characterization of
`controlled release multi-particulate beads formulated with a customized cellulose
`acetate butyrate dispersion. International journal of pharmaceutics, 234(1), 179-193
`77. Nazzal, S., Smalyukh, I. I., Lavrentovich, O. D., & Khan, M. A.* (2002).
`Preparation and in vitro characterization of a eutectic based semisolid self-
`nanoemulsified drug delivery system (SNEDDS) of ubiquinone: mechanism and
`progress of emulsion formation. International journal of pharmaceutics, 235(1), 247-
`265.
`78. Agarwal, V., Reddy, I. K., & Khan, M. A.* (2001). Polymethyacrylate based
`microparticulates of insulin for oral delivery: preparation and in vitro dissolution
`stability in the presence of enzyme inhibitors. International journal of
`pharmaceutics, 225(1), 31-39.
`79. Agarwal, V., Nazzal, S., Reddy, I. K., & Khan, M. A.* (2001). Transport studies of
`insulin across rat jejunum in the presence of chicken and duck ovomucoids. Journal
`of Pharmacy and Pharmacology, 53(8), 1131-1138.
`80. Agarwal, V., & Khan, M. A.* (2001). Current status of the oral delivery of insulin.
`Pharm. Technol, 10, 76-90.
`81. Guven, N., Nazzal, S., and Khan, M. A.* 2003). Powder X-Ray Diffraction of
`Ubiquinone, Powder Diffraction File.
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`82. Shah, R. B., Ahsan, F., & Khan, M. A.* (2002). Oral delivery of proteins: progress
`and prognostication. Critical Reviews™ in Therapeutic Drug Carrier Systems, 19(2).
`83. Nazzal, S. and Khan, M.A.*(2002). Lipid Based Formulation for the Development
`of a Nutritional Supplement for Oral Delivery of Ubiquinone, Drug Del. Tech, 2, 68.
`84. Ahsan, F., Rivas, I. P., Khan, M. A., & Suarez, A. I. T. (2002). Targeting to
`macrophages: role of physicochemical properties of particulate carriers—liposomes
`and microspheres—on the phagocytosis by macrophages. Journal of controlled
`release, 79(1), 29-40.
`85. Nazzal, S., & Khan, M.A.*(2002). Response surface methodology for the
`optimization of ubiquinone self-nanoemulsified drug delivery system. AAPS
`PharmSciTech, 3(1), 23-31.
`86. Zaghloul, A. A., Gurley, B., Khan, M.A., Bhagavan, H., Chopra, R., & Reddy, I.K.
`(2002). Bioavailability assessment of oral coenzyme Q10 formulations in dogs. Drug
`development and industrial pharmacy, 28(10), 1195-1200.
`87. Nazzal, S., Nutan, M., Palamakula, A., Shah, R., Zaghloul, A. A., & Khan, M.A.*
`(2002). Optimization of a self-nanoemulsified tablet dosage form of Ubiquinone
`using response surface methodology: effect of formulation ingredients. International
`journal of pharmaceutics, 240(1), 103-114.
`88. Vaithiyalingam, S., Nutan, M., Reddy, I., & Khan, M.A.* (2002). Preparation and
`characterization of a customized cellulose acetate butyrate dispersion for controlled
`drug delivery. Journal of pharmaceutical sciences, 91(6), 1512-1522.
`89. Vuppagalla, R., Agarwal, V., and Khan, M.A.* (2003). A Simple High Performance
`Liquid Chromatographic Method for Simultaneous Analysis of Insulin and
`Ovomucoid, Pharmazie, 58(11), pp. 793-5.
`90. Taha, E. I., Zaghloul, A. A. A., Kassem, A. A., & Khan, M. A.* (2003). Salbutamol
`sulfate suppositories: influence of formulation on physical parameters and stability.
`Pharmaceutical development and technology, 8(1), 21-30.
`91. Zaghloul, A. A., Hussain, A., Khan, M. A., & Ahsan, F. (2003). Development of a
`HPLC method for the determination of cyclosporin-A in rat blood and plasma using
`naproxen as an internal standard. Journal of pharmaceutical and biomedical
`analysis, 31(6), 1101-1107.
`92. Shah, R. B., Siddiqui, A., Shah, G., & Khan, M.A.*(2003). A validated HPLC assay
`for simultaneous analysis of salmon calcitonin and duck ovomucoid. Die Pharmazie-
`An International Journal of Pharmaceutical Sciences, 58(9), 620-622.
`93. Motlekar, N. A., Shah, R. B., Reddy, I. K., Keller, W. J., & Khan, M.A.*(2003).
`Permeation of genistein through human skin. Pharmaceutical technology, 27(3), 140-
`148.
`94. Afouna, M. I., Fincher, T. K., Khan, M. A., & Reddy, I. K. (2003). Percutaneous
`permeation of enantiomers and racemates of chiral drugs and prediction of their flux
`ratios using thermal data: a pharmaceutical perspective. Chirality, 15(5), 456-465.
`95. Haase, M.R., Khan, M.A., and Bonilla, J. (2003). Stability of Two Concentrations of
`Tiagabine in an Extemporaneously Compounded Suspension, Int. J. Comp.,
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`7(5):485-89.
`96. Hussain, A., Arnold, J. J., Khan, M. A., & Ahsan, F. (2004). Absorption enhancers
`in pulmonary protein delivery. Journal of controlled release, 94(1), 15-24.
`97. Shah, R. B., Palamakula, A., & Khan, M. A.* (2004). Cytotoxicity evaluation of
`
`enzyme inhibitors and absorption enhancers in Caco(cid:486)2 cells for oral delivery of
`98. Mustafa, F., Yang, T., Khan, M. A., & Ahsan, F. (2004). Chain length(cid:486)dependent
`
`salmon calcitonin. Journal of pharmaceutical sciences, 93(4), 1070-1082.
`
`effects of alkylmaltosides on nasal absorption of enoxaparin. Journal of
`pharmaceutical sciences, 93(3), 675-683.
`99. Shah, R. B., & Khan, M. A.*(2004). Protection of salmon calcitonin breakdown
`with serine proteases by various ovomucoid species for oral drug delivery. Journal of
`pharmaceutical sciences, 93(2), 392-406.
`100. Palamakula, A. and Khan, M. A.*, Evaluation of Cytotoxicity of Oils Used in
`Coenzyme Q10 Self-Emulsifying Drug Delivery Systems (SEDDS), Int. J. Pharm.,
`(2004), 273(1), 63-73.
`101. Taha, E., Zaghloul, Z. A., Al-Saidan, S., and Khan, M. A.*, Bioavailability
`Assessment of Salbutamol Sulfate Suppositories in Human Volunteers, Int. J.
`Pharm., (2004), 279(1), 3-7.
`102. Palamakula, A., Nutan M. and Khan, M. A.*, Response Surface Methodology for
`Optimization and Characterization of Limonene Based Coenzyme Q10 Self-
`Nanoemulsified Capsule Dosage Form, AAPSPhamSciTech, (2004), 5(4), 114-121
`103. Shah, R. B., Nutan, M. T., and Khan, M. A.*. ‘Preparation and Characterization Of
`Dual Controlled Gastrointestinal Therapeutic System Of Salmon Calcitonin And
`Turkey Ovomucoid’ Clin. Res. Reg, Affairs, (2004), 21, pp. 81-96.
`104. Shah, R. B. and Khan, M. A.*. Regional Permeability Of Salmon Calcitonin In
`Isolated Rat Gastrointestinal Tracts: Transport Mechanism Using Caco-2 Cell
`Monolayer’, AAPS Pharm Sci., (2004), 6(4), pp. 36-40
`105. Palamakula, A., Soliman, M., Reddy, I. K. and Khan, M. A.*., Preparation And In
`Vitro Characterization Of Self-Nanoemulsified Capsules With Limonenes, Pharm.
`Technol., (2004), pp. 74-88.
`106. Taha, E. I., Al-Saidan, S., Samy, A. M. and Khan, M.A.*, Preparation and in-vitro
`characterization of self-nanoemulsified drug d elivery system (SNEDDS) of all trans-
`retinol acetate, Int. J. Pharm., (2004), 285(1), pp. 109-19.
`107. Shah, R. B., Nutan, M. T., Reddy, I. K. and Khan, M. A.*. A dual controlled
`gastrointestinal therapeutic system of salmon calcitonin. II. Screening of process and
`formulation Variables. Clinical Research and Regulatory Affairs, (2004), 21(3-4),
`pp. 231-238
`108. Soliman, M., and Khan, M.A.*. Preparation and in vitro characterization of semi-
`solid dispersion of flurbiprofen with Gelucire 44/14 and Labrasol, Pharmazie, (2005),
`60(4), pp. 288-293.
`109. Taha, E. I., Samy, A. M., Kassem, A. A., and Khan, M.A. *. Response surface
`methodology for the development of self-nanoemulsified drug delivery system
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`(SNEDDS) of all-trans-retinol acetate. Pharmaceutical development and technology,
`(2005), 10(3), pp. 363-370.
`110. Nutan M.T., Soliman, M.S., Taha, E. I., & Khan, M. A. *. Optimization and
`characterization of controlled release multi-particulate beads coated with starch
`acetate. International journal of pharmaceutics, (2005), 294(1), pp. 89-101.
`111. Vaithiyalingam, S., Ahmed, S. and Khan, M. A. *. Current Status of Controlled
`Drug Delivery. Drug Deliveries Companies Report (UK), (2005), 30-33.
`112. Shah, R. B. and Khan, M. A.*. ‘Oral Delivery of Salmon Calcitonin with
`Ovomudoids’ Amer. Pharm. Rev., (2005), 8(1), 45-47.
`113. Palamakula, A., Soliman, M., & Khan, M. A. *. Regional permeability of coenzyme
`Q10 in isolated rat gastrointestinal tracts. Die Pharmazie-An International Journal of
`Pharmaceutical Sciences, (2005), 60(3), 212-214.
`114. Zaghloul, A. A. A., Mustafa, F., Siddiqu, A., & Khan, M. A. *. Biodegradable
`microparticulates of beta-estradiol: preparation and in vitro characterization. Drug
`development and industrial pharmacy, (2005), 31(8), 803-811
`115. Shah, R. B., Hullahalli, P. R., Tawakkul, M. A., Faustino, P. J., Nguyenpho, A., &
`Khan, M. A. *. Development of a validated stability indicating HPLC method for
`ranitidine hydrochloride syrup. Clinical Research and regulatory affairs, (2006),
`23(1), 35-51.
`116. Nazzal, S., & Khan, M. A. *. Controlled release of a self-emulsifying formulation
`from a tablet dosage form: Stability assessment and optimization of some processing
`parameters. International journal of pharmaceutics, (2006), 315(1), 110-121.
`117. Motlekar, N., Khan, M. A. *, & Youan, B. B. C.. Preparation and characterization of
`genistein containing poly (ethylene glycol) microparticles. Journal of applied
`polymer science, (2006), 101(3), 2070-2078.
`118. Zaghloul, A. A., Mustafa, F., Siddiqui, A., & Khan, M. A. *. Response surface
`methodology to obtain β-estradiol biodegradable microspheres for long-term therapy
`of osteoporosis. Pharmaceutical development and technology, (2006), 11(3), 377-
`387.
`119. Wu, H., Shen, M., Wheelock, T. D., & Khan, M. A. *. Engineering Considerations
`on Modeling for Pharmaceutical Process Analytical Technology (PAT) Applications.
`In The 2006 Annual Meeting, November 12-17, (2006)
`120. Wu, H., & Khan, M. A. *. Mapping the State of a Pharmaceutical Co-precipitation
`Process: An Integrated Process Analytical Technology (PAT) Approach. In
`Conference Proceedings of the 2006 AIChE Annual Meeting (CD-ROM). AIChE
`Proceeding P-235, ISBN: 0-8169-1012-X., November 12-17, (2006)
`121. Zidan, A. S., Sammour, O. A., Hammad, M. A., Megrab, N. A., Habib, M. J., &
`Khan, M. A. *. Process analytical technology: non-destructive assessment of
`anastrozole entrapment within PLGA microparticles by near infrared spectroscopy
`and chemical imaging. Journal of microencapsulation, (2008), 25(3), 145-153.
`122. Zidan, A. S., Sammour, O. A., Hammad, M. A., Megrab, N. A., Hussain, M. D.,
`Khan, M. A. *, & Habib, M. J.. Formulation of anastrozole microparticles as
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`biodegradable anticancer drug carriers. AAPS PharmSciTech, (2006), 7(3), E38-E46.
`123. Nutan, M. T., Vaithiyalingam, S. R., & Khan, M. A. *. Controlled release
`multiparticulate beads coated with starch acetate: Material characterization, and
`identification of critical formulation and process variables. Pharmaceutical
`development and technology, (2007), 12(3), 307-320.
`124. Wu, H., Hussain, A. S., & Khan, M. A. *. On-line Process Control and Process
`Analytical Technology: Integration of Chemical Engineering Practice into
`Semiconductor and Pharmaceutical Industries. Chemical Engineering
`Communication,(2007), 194, 760-779.
`125. Zidan, A. S., Sammour, O. A., Hammad, M. A., Megrab, N. A., Habib, M. J., &
`Khan, M. A. *. Quality by design: Understanding the product variability of a
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`self(cid:486)nanoemulsified drug delivery system of cyclosporine A. Journal of
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`pharmaceutical sciences, (2007), 96(9), 2409-2423.
`126. Zidan, A. S., Sammour, O. A., Hammad, M. A., Megrab, N. A., Habib, M. J., &
`Khan, M. A. *. Quality by design: Understanding the formulation variables of a
`cyclosporine A self-nanoemulsified drug delivery systems by Box–Behnken design
`and desirability function. International journal of pharmaceutics, (2007), 332(1),