Petitioner: Haag-Streit AG
`Petitioner: Haag-Streit AG
`
`Ex. 100(cid:22)
`
`EX. 1003
`
`

`

`
`
`
`
`'4us.pram"‘
`
`56929
`
`
`
`
` FEE
`
`
`
`illllillllllllllllllllillillllli
`
`
`,
`
`12/93”
`
`ttttt
`
`
`—-_——r
`
`
`
`
`1
`
`
`
`
`mums
`
`
`
`
`
`
`
`“A.“
`Wat-aver "
`0“
`L
`”t
`\ v
`‘ PCCAKW
`
`
`
`mt“
`‘23
`4
`
`_,.»
`
`i M”. M .,
`
`
`
`
`
`
` TERMINAL
`
`
`DISCLAIMER/
`
`
`
` g The term of this patent shall
`
`/ DRAWINGS
`Total Claims
`
`
`Print Fig.
`Sheets Drwg.
`'"ZC?
`
`
`
`_ The term of this patent
`
`
`
`(date)
`subsequent to
`(Assistant Examiner)
`has been disclaimed.
`
`
`
`
`not extend beyond the expiration date
`of U.S Patent. No.
`
`
`Date Paid
`Amount Due
`
`
`
`
`(0/;41m
`(Dale)
`
`
`
`
`l’éZCl “0‘3
`
`ISSUE BATCH NUMBER
`
`
`
` E The terminal
`months of
`/2/N?/_(Datei‘
`
`
`
`
`V this patent have been disclaimed.
`
`(Legal instruments Examiner)
`
`
` WARNING:
`
`
`The information disclosed herein may be restricted. Unauthorized disclosure may be prohibited by the United States Code Title 35, Sections 122. 181 and 368.
`Possession outside the US. Patent & Trademark Office is restricted to authorized employees and contractors only,
`
`Fm PTO-436A
`(Rev. 6/99)
`
`
`
`FILED WITH: [:| DISK (CRF) [j FICHE E] CD-FlOM
`‘
`.
`.
`V
`(Attached In pocket on right inside flap i
`
`issue the int—m:
`
`ISSUE We i A.
`
`4m: m5't‘
`
`-
`
`~
`
`l
`
`i
`
`(FACE)
`
`
`
`

`

`iliiiiiliiilliiiiiiiiiiiili’iiim
`1
`”976873.
`.
`_
`
`.1759”! 11.5. P
`iiiiiiii‘iiimii
`CONTENTS
`Date Received
`(incl. C. of ME)
`or
`
`Date Mailed
`
`W;
`
`> Date Received
`(Incl. C. of M.)
`or ,
`
`Date Mailed
`
`
`42.
`43.
`'
`>
`
`44.
`
`
`L
`
`i.
`f
`
`1. Application
`
`papers.+F7147/76
`
`-
`
`
`
`45.
`
`46.
`
`47.
`48.
`
`49.
`50.
`
`51.
`52.
`
`53.
`
`
`
`
`_
`.. ___._ '
`
`.
`
`-
`
`L
`
`_
`
`,
`
`W
`
`.
`
`$7“
`
`,_
`_
`
`_.fl;._
`
`
`
`
`
`
`
`
`54.
`
`55.
`
`56.
`
`57.
`
`
`
`
`
`53.
`
`59.
`
`
`
`
`
`60.
`
`61.
`
`62.
`
`63.
`
`64.
`
`ii
`
`
`
`
`
`
`
`55.
`
`66.
`
`67.
`
`68.
`
`70.
`
`71.
`
`69.M ___,v_
`
`
`
`
`72.
`
`_ _.._*w
`
`
`73.
`
`74.
`
`
`
`
`
`
`
`75.
`
`76.
`
`77. ____________.__._ _._____e
`
`
`A
`
`78.
`79.
`
`80.
`
`
`
`____
`
`
`41.
`
`81.
`
`82-
`
`(LEFT OUTSIDE)
`
`

`

`ISSUE SLIP STAPLE AREA (for additional crpss references)
`
`,
`
`POSITION
`
`"— T iNITlTAL'.,1
`
`'
`
`‘
`
`ID No.
`
`DATE
`
`
`
`
`
`
`
`FEE DETERMINATION
`; O.|.P.E. CLASSIFIER ‘
`‘ FORMALITY REVIEW
`RESPONSE FORMALITY REVIEW
`L__
`
`
`'
`*
`'
`‘
`
`
`72?”
`3
`frayed l
`of} wy— Qj
`'51 4....
`£53
`/0 /
`giégwflfllhe—Jfl¥%iié—
`INDEX OF CLAIMS
`.1 ................................. Rejected
`N ................................. Non-elected
`= ................................. Allowed
`|
`................................. Interference
`— (Through numeral)... Canceled
`A ................................. Appeal
`+ ................................. Restricted
`0 ................................. Objected
`
`
`Claim
`.
`Date
`Claim
`Date
`Claim
`,J
`Date
`E
`- *9CWT——
`
`SE g
`EE
`E?
`LL 0
`k
`u’. o
`T
`LT- O
`__4
`
`r
`451
`4101
`l 1d 5;
`
`52
`102
`'1,
`2
`7’)
`3
`J‘
`T
`T
`H 103
`v
`
`
`
`
`T
`l
`T
`fix 4 Q
`104
`
`F 5 IO
`_
`105
`‘
`
`
`to!
`6 9
`‘
`l
`T106
`’ m '
`
`'7‘ 7 Q T:‘
`7107*"—
`‘
`
`43
`a}!~
`1013
`‘
`_ _Tsa
`L
`T
`_
`(’T
`9
`‘3
`109
`59
`
`
`
`
`
`
`,
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`
`Ilfmore than 150 claims or 10 actions
`staple additiorf‘al sheet here
`
`(LEFT INSIDE)
`
`
`
`-
`
`
`
`

`

`
`SEARCH NOTES
`SEARCHED
`
`(INCLUDING SEARCH STRATEGY)
`
`
`
`
`
`
`
`
`
`
`INTERFESRENCE SEARCHED
`
`(RIGHT OUTSIDE)
`
`

`

`Page 1 ofl
`
`ffl
`
`(f I
`“‘ ~
`\. UNITED STATES PATENT AND TRADEMARK OFFICE
`
`s,
`
`‘4
`
`COMMISSIONER FOR PATENTS
`WASHINGTCA. D.C, 2023i
`UNITED STATES PATENT AND TRADEMARK OFFICE
`wwwmspfogov
`
`lllllllllllllllllII|ll|lIlIII|l||lll|llllllllllllllllllllll
`Bib Data Sheet
`
`CONFIRMATION NO.1784
`
`SERIAL NUMBER
`09/758,731
`
`A PPLICANTS
`
`FILING DATE
`01,2
`0
`4’20 1
`RULE
`
`‘
`
`Victor J. Doherty, Wellesley, MA;
`
`* CONTINUING DATA *fi*fi*******fi****fl****i*iv*i
`THIS APPLICATION IS A CIP OF 09/175,79610/20/1998 ABN
`
`* FOREIGN APPLICATIONS *Ri****t*tk****k*w*k
`
`"
`GROUP ART UNIT
`2872
`
`ATTORNEY
`DOCKET No.
`389841
`
`Foreign Priority claimed
`,.
`35 USC119(a-d)condmons
`erified and
`me‘
`‘
`
`1‘
`E] yes B’no D Metafter
`Allaance
`Examiner‘s Signature
`
`initials
`
`
`
`STATE 0R
`COUNTRY
`MA
`
`SHEETS
`DRAWING
`5
`
`CLAIMS
`20
`
`Curtis A, Vock, Esq.
`Lathrop, Gage & Sullivan
`Suite 302
`. 845 Pearl East Circle
`Boulder ,CO 80301
`TITLE
`
`Hand-held Ophthalmic illuminator
`
`FILING FEE FEES: Authority has been given in Paper
`RECEIVED NO.
`to charge/credit DEPOSIT ACCOUNT
`for following:
`
`:1 1117 Fees ( Processing Ext. 0f
`tlme)
`
`‘_
`
`D All Fees
`
`CI 1.16 Fees(Filing)
`
`
`
`
`
`
`
`.3.
`
`

`

` ~
`
`,_
`
`ELeeez454sous
`
`/
`// 1795’0/
`/‘
`.:
`PT isB/os ( a—oo)
`:roved for use through 10/3/2002. OMB 08510032
`u 3. Patent a.
`Please type a blur; sign (+) instrte this:
`11
`temark Oiiice; Us. DEPARTMENT OF COMMERCE
`
`Under the Pe-erwork Resection Act of 1995 no ersons are re-urred to resend to a collection o1 ‘nuglrmatlon unless it dis-la s a valid OMB control number
`r
`
`UTILITY
`3898le
`Attorney DooketNo.
`
`
`-
`TRANSMITTAL
`
`
`
`
`
`- fun/y for new nonprovisional application under 37 OFF?
`,s.‘£tlb))
`
`Express Mail Label No.
`
`
`
`APPLICATION ELEMENTS
`
`Assistant Commissioner for Patents
`-
`Box Patent Application
`ADDRESS TO' Washington, Dc 20231
` See MPEP chapter 600 concerning utility patent application contents,
`
`
`
`Fee Transmittal Form (eg. PTO/88117)
`
`
`
`(Submit an original anda duplicate Iorfee processing)
`7~
`CD'HOM 0’ CD‘R m duplicate, [5199 table or Computer
`
`Applicant claims small entity status.
`See 37 CFR 1.27.
`
`8. Nucleotide and/or Amino Acide Sequence Submission
`
`
`(if applicable, all necessary)
`
`
`
`Specification
`[Total Pages _10_ ]
`(preferred arrangement set forth below)
`
`
`a.
`Computer Readable Form (CHF)
`~ Descriptive title of the invention
`
`b. Specification Sequence Listing on:
`
`- Cross Reference to Related Applications
`
`
`
`i.
`CD-FlOM or CD-R (2 copies); or
`
`
`
`~ Statement Regarding Fed sponsored Ft & D
`
`ii.
`paper
`- Reference to sequence listing, a table,
`
`or a computer program listing appendix
`
`
`- Background ofthe Invention
`
`Statements verifying identity of above copies
`c.
`
`
`~ Brief Summary of the Invention
`
`
`- Brief Description of the Drawings (if filed)
`- Detailed Description
`
`- Claimts)
`
`- Abstract of the Disclosure
`
`
`[ Total Sheets _6___ 1
`Drawingts) (35 u.s.c. 113)
`ACCOM PANYINGAEPLICATrON PARTSm
`
`[ Total Pages _4._]
`Oath or Declaration
`9.
`Assignment Papers (cover sneetal-dooumenttsl)
`
`
`10.
`STCFR 3.730)) Statement
`X ‘Poirver of Attorney
`a.
`Newly executed (original or copy)
`(when there IS an assrgnee)
`
`b‘ X Copy from a prior application (37 CFR 1.63 (d))
`Engtr hTranslatlon Document (if applicable)
`(for continualion/divislonal v'vith Box 17 completed)
`
`
`information Disclosure
`_
`Copies of "33 Citations
`
`
`Statement (lDS)/PTO_,~1449
`l.
`DELFl'lON OF INVENTOFt S
`
`PreliminaryAmendn‘vent
`Signed statement attached deleting inventorls)
`named in the prior application, see 37 CFR
`
`1.ss(d)(2) and 1.33m).
`
`
` Application Data Sheet. See 37 CFFl 1.76
`
`
`If a CONTINUING APPLICATION, check appropriate box, and supply the requisite Information
`17.
`Application Data Sheet Under 37 CH? 1.76:
`X Continuation (ClP)
`Continuation
`Divrsronai
`Examiner _J. Treas
`Prior application lnlorrnatlcn
`
`
`
`
`
`
`
`
`
`11.,
`12.
`13.
`
`14. X Fteturnfleceipl Postcard (MPEP 503)
`(Should be specifically itemized)
`Certified Copy of Priority Dooument(s))
`{if foreign priority is claimed)
`
`15.
`
`w and in a preliminary amendment, or in an
`‘ "
`ot prior application No: 09/175,796
`
`.
`
`
`
`
`
`18. CORRESPONDENCE ADDRESS
`
`{Insert Customer No, orAttach bar code label hers)
`
`,X Correspondence address beiow
`
`Customer Number or Bar Code Label
`
`
`
`
`
`
`
`NamerrnmperM HelgsrarmnaNrAromer/Agenv m
`Mlfla!
`-”/
`Burden Hour Statement. This to
`is estimated to take 02 hours to complete Time will Vary depending man the needs of the individual rase A
`comments on the amount of time you
`are required to complete this to rn should be sent to the Chief Information Oflicer, US. Patent and Trademark Office, Washington, DC 20231. DO NOT SEND FEES OFt COMPLETED
`FORMS TO THIS ADDRESS. SEND TO: Assistant Commissioner tar Patents, Box Patent Application, Washington, DC 20231
`g:‘1
`8647271
`
`
`
`

`

`PIG/513117 (0800)
`L
`, Approved for use through 10/31/2002. OMB 0651-0032
`U.S. Patent and Trademark Office: US. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 19951 no persons are required to respond to a collection of information unless it displays a valid OMB control number.
`
`FEE TRANSMITTAL
`
`forpyzooo
`
`-
`
`,
`
`
`
`
`1.
`
`2.
`
`The commissioner is hereby authorized to charge indicated fees and
`
`credit any nVfii‘i’t‘yments to:
`Deposit Aewunt Number 12-0600
`
`Deposit Account Name
`Lathrop & Gage LC
`X
`Charge Any Additional Fee Required Under 37 CFR 1.16 and 1,17
`
`X
`Applicant claims small entity status, See 37 CFR 1.27
`
`x
`Payment Enclosed:
`X
`Check
`0015f
`
`Credit Card
`
`Money Order
`
`FEE CALCULATION
`
`lice Description
`
`_
`
`BASIC FILING FEE
`Large
`Entity Small Entity
`Fee
`Fee
`Fee
`Fee
`Fee Paid
`€056
`(3)
`Code
`(3)
`Utility filing fee _
`101
`710
`201
`355
`Design filing fee
`__
`106
`320
`206
`160
`Plant filing fee
`_
`__
`107
`490
`207
`245
`Reissue filing fee
`‘_
`108
`710
`208
`355
`Provisional filing fee _
`1 14
`150
`214
`75
`SUBTOTAL (1)
`($)____
`
`'
`
`,
`
`
`
`
`
`
`
`ADDITIONAL FEES
`Large
`Entity Small Entity
`Fee
`Fcc
`Fee
`Fee
`Code
`(S)
`Code
`($)
`
`.
`
`,
`
`Fee Description
`
`105
`127
`
`139
`147
`112
`
`113
`
`115
`116
`117
`118
`128
`119
`120'
`121
`138
`140
`‘ 141
`142
`143
`144
`122
`123
`
`‘
`
`,
`
`179
`
`130
`50
`
`205
`227
`
`139
`130
`147
`2,520
`920* ' 112
`
`1,840‘ 113
`
`.
`
`110
`390
`890
`1,390
`1, E90
`310 4
`310
`270
`1,510
`110
`1,240
`1,240
`440
`600
`130
`50
`2/10
`
`40
`
`710
`710
`
`710
`
`1
`
`,1
`
`'
`
`65
`25
`
`Surcharge - late filing fee or oath
`Surcharge - late provisional tiling
`fee or cover sheet
`Non-English specification
`130
`licr filing a request for ex pane
`2.520
`reexamination
`920‘ Requesting publication of SIR prior
`to Examiner action
`.
`,
`1,840‘ Requesting publication‘of SIR after
`14’
`‘ Examinei’nction
`55
`Extension for reply within first month
`195
`Extension for reply Within second month
`445
`Extension for reply Within third month
`695
`Extension for reply within fourth month
`945,
`Extension for reply within fifth moidh
`155
`Notice of Appeal
`155
`Filing a brief in support of an appeal
`135
`Request for oral hearing
`.
`1.5.10 Petition to institute a public use
`‘.
`Proceeding
`55
`Petition to revive ~ unavoidable
`620
`Petition to revive - unintentional
`620
`Utility issue fee (or reissue)
`220
`Design issue fee
`300
`Plant issue fee
`130
`Petitions to the Commissioner
`50
`Petitions related to provisional
`Applications
`240
`Submission oflnformation
`Disclosure Statement
`Recording each patent assigrunent
`Per property (times number ofproperties)
`Filing a submission aficr final
`Rejection (37 CFR§ 1.129119)
`For each additional invention to be
`Examined (37 CPR § 1.1749071)
`Request for Continued Examination
`(RC5)
`Request for expedited examination
`of a design applicatim
`
`900
`169
`Other fee (specify)
`*Roduced by Basic Filing Fee Paid
`
`SUBTOTAL (3)
`
`($)
`
`445.00
`
`EXTRA CLAJM FEES
`
`Fee from
`Fee Paid
`below
`Extra Claims
`= _
`X __
`otul Claims __ ‘20“ = _
`dependent
`lai ms
`__
`- 3““ = *— X _ = _
`Multiple Dependent
`_
`= _
`* *or number previously paid, ifgreater,‘ For Reissues, see below
`
`
`
`Fee Description
`
`Large
`Fee
`Code
`103
`102
`104
`109
`110
`
`Entity Sinnll Entity
`Fee
`lice
`Fee
`($)
`Code
`(3)
`18
`203
`9
`80
`202
`40
`270
`204
`135
`80
`209
`40
`18
`210
`9
`
`Claims in excess of 20
`Independent claims in excess of 3
`Multiple dependent claim, it not paid
`“Reissue independent claims over original patent
`* *Reissue claims in excess of 20 and over original
`patent
`SUBTOTAL (2)
`
`(SS)
`
`
`
`SUBMITTED BY
`
`Name (Print/[wet
`
`Curtis A, Vock
`
`Reg'stration Sop
`(Attorney/Agent)
`
`
`
`Telephone
`
`303-449~5 800
`
`Complete (if applicable)
`
`—l .4 no
`
`WARNING: Infonuation on this form may become public. Credit card infunnalion should not be included on this tom]. Provide credit card infurmation and outlwfizntimi
`
`onPTO-ZDSS.
`
`.m
`
`

`

`Practitioner’s Docket No. 389841
`
`’
`
`.
`
`PA TENT '
`
`
`
`IN THE UNITED STATES PATENT AND TRADEMARK OFFICE
`
`In re application of:
`Application No.:
`Filed:
`
`Victor J. Doherty
`09/ 175,796
`October 20, 1998
`
`Group No.:
`Examiner:
`
`2872
`I. Treas
`
`For:
`
`HAND HELD OPHTHALMIC ILLUMINATOR
`
`Box Patent Application
`Commissioner for Patents
`Washington, DC. 20231
`
`EXPRESS MAIL CERTIFICATE
`
`”Express Mail“ label number EL656245460US
`Date of Deposit: January 24, 2000
`
`Ihereby state that the following attached papers
`
`,
`
`at;
`
`.
`
`.
`
`»_
`
`.
`
`.
`
`'
`
`i a
`
`1. Utility/CIP Patent Application Transmittal (1 page)
`2. Fee Transmittal (1 page)
`3 Check No. 2061 in the amount of $445.00
`4
`Specification (6 pages)
`5. Claims (3 pages, claims numbered 1—20)
`6. Abstract (1 page)
`Drawings (6 pages figures 1-7
`Declaration and Power of Attorney (4 pages)
`Petition for 3 Month Extension (1 page)
`0. Certificate of Mailing — 1 page
`
`7 8 9
`
`1
`
`’
`
`.
`
`are being deposited with the United States Postal Service ‘Express Mail Post Office to Addressee‘ service
`under 37 CFR 1. 10 on the date indicated above and1s addressed to: Box Patent Application, Commissioner
`for Patents, Washington, D.C. 20231.
`
`
`
`Nancy Halas
`
`ay-
`
`
`
`
`

`

`Abstract
`
`including a battery, an electrical
`The invention provides an ophthalmic illuminator,
`resistor, an electrical switch and an LED. The battery is in circuit with the battery; and
`the electrical switch is in circuit with the resistor, where electrical energy flows through
`the circuit when the switch is in the closed’ position. The light emitting diode is in circuit
`with the switch and generates blue light energy which in turn causes fluorescence in a
`
`fluorescien dye administered to the patient’s eye when the switch is in the closed
`position. An optical element (eg, a lens or reflector) can be disposed between the diode
`and the eye to increase blue light energy reaching the eye. The energy can be “pulsed”
`such that the diode generates the blue light at‘a predetermined frequency. A user of the
`illuminator, e.g., a physician, can hold the system by hand to operate the switch (e.g.,
`through a button). A magnifier coupled to the system provides a magnified” image of the
`patient’s eye, if desired. Preferably, an annular housing integrates the LED (or a pltirality
`of LEDs) together suchthat a button activates and generates the» blue light energy, and a
`user views through the center of the housing, through a magnifier therein, to View the
`patient’s eye.
`
`fig,
`
`
`
`”1
`
`

`

`‘y. Docket No. 389841
`
`Hand-Held Qphthalmic llluminator
`
`Related Applications
`
`This applicationis a continuation--1n—part of, and claims priority to, commonlyowngdgpd
`{U
`‘3»
`co--pending US Application No. 09/175,,796 filed on October 20, 1998\and hereby
`incorporated by reference.
`
`Background of the Invention
`
`Ophthalmologists, optometrists and other medical doctors and health care professionals
`frequently are required to examine the cornea of the human eye for scrapes ab1as1ons -.
`di1t or foreign bodies The current technology utilizes a battery operated hand—held 7
`pcnlight illuminatorin conjunction with a solution of Sodium Fluorescein. Anexample of”:
`an existing prior art device is the Solan Blu-Slit® manufactured by‘Xomed Surgical
`Products, Inc. of Jacksonville, FL. The penlight illuminator typically uses conventional
`batteries as a power source and an incandescent or halogen light bulb A cobalt blue filter
`attached over the lamp filters the white light emitted bythe bulb to produce a blue beam.
`This blue beam is used to illuminate the patients eye after application of the Sodium
`Fluorescein dye.
`
`
`
`The fluorescein dye, which is typically impregnated in sterile paper, is administered by
`the physician in the following manner. The ,patient’s upper eyelid is retracted and the
`sodium fluorescein impregnated paper applicator
`is made to contact
`the bulbar
`conjunctiva of the eye at the temporal side. The applicator is removed and the eyelid is
`opened and closed several times to allow diffusion of the dye over the entire conjunctiva]
`area and cornea.
`
`The fluorescein dye tends to accumulate in epithelial defects of the cornea and
`illumination of the eye will cause the defect to fluoresce vividly. By using blue filtered
`light to illuminate the eye of the patient, which. has been dyed with fluorescein,
`this
`
`,1»
`
`

`

`fluorescenceis most observable. The amount of fluorescence observable is proportional
`
`to the accumulation of the fluorescein or the magnitude of the defect. However,
`
`the
`
`magnitude of the fluorescence is also proportional to both the intensity and spectral purity
`
`of the light illuminating the patient’s eye. In other words, a brighter and more spectrally
`pure beam will show more detail and thus is more desirable to the physician.
`
`Summary of the Invention
`
`The subject of this invention is a device which is used to illuminate a patient’s eye that
`
`has been administered with a fluorescent dye for the purpose of examining the eye for
`
`epithelial defects. The invention in its simplest form utilizes four components: a battery.
`
`an electrical resistor, an electrical switch and a blue light emitting diode,
`
`Brief Description of the Invention
`
`Figure 1 depicts an electrical schematic of an ophthalmicilluminator utilizing a blueLED
`source according to the invention
`Figure 2 shows an alternative ophthalmic illuminator of the invention.
`Figuie 3 shows a perspective View of a hand held eye illuminator constructed according
`to the invention.
`
`Figure 4 shows a perspective View of another hand held eye illuminator constructed
`
`according to the invention.
`
`Figure 5 shows a perspective interior view of the illuminator of Figure 4.
`
`Figure 6 shows a perspective View of another hand held eye illuminator constructed
`
`according to the invention.
`
`Figure 7 shows a perspective interior View of the illuminator of Figure 6.
`
`Detailed Description of the Invention
`
`In schematic 10 of Figure 1, when the switch 12 is closed electrical energy from the
`
`battery 14 flows through the circuit 10 and causes the blue LED 16 to produce blue light
`
`
`
`«23
`
`a)“
`
`

`

`18. The resistor 20 is used to limit the current that is applied to the LED 16 as per the
`manufacturer specification: which is typically 20 to 30 milli—amps. Certain LED’s have an
`internal resistor 20 built into the LED package, as known in the art. Battery 14 voltage is
`typically four to twelve volts DC. The blue LED’s are for example manufactured by both
`CREE and NICHIA and typically produce illumination on the-order of 0.50 candle or
`more at a wavelength of 450 nano—meters with a typical bandpass of 50mm. These LED’s
`typically are comprised of Gallium Nitride on a Silicon Carbide substrate (NICHIA) or
`just Silicon Carbide (CREE). In one embodiment of the invention, resistor 20 is not
`
`required; rather, battery 14 serves as the resistor for circuit 10.
`
`The ophthalmic illuminator as depicted in Figure l is superior to the current incandescent
`technology for the following reasons: first, the blue LED 16 emits more illumination in
`the desired blue spectrum (425 to 475 NM) than the filtered incandescent lamp which
`results in more fluorescence of the fluorescein dyed eye 22 and thus has better sensitivity;
`second, the blue LED 18 uses less power than a blue optically filtered incandescent or
`halogen bulb so that the battery power source 14 should last significantly longer; third,
`the invention is simpler to the prior art technology in that there is no need for a blue
`bandpass Optical filter.
`
`ll
`
`There are a number of enhancements that can be made to the basic invention as shown in
`
`Figure 1. First, a lens 24 may be added close to the LED 18. between the LED 18 and the
`
`patient’s eye 22 to maximize the light collection efficiency of the system. A reflector
`could be added separately or used in conjunction with a lens for the same purpose.
`Second, the electrical circuit 10 could be modified with a pulse means 13 to cause the
`blue LED 16 to operate in a pulsed mode instead of continuous mode. This would enable
`higher peak current to be applied to the blue LED 16 to produce the appearance of an
`even brighter beam and hence more fluorescence sensitivity to the physician. Third, a
`simple magnifier tens could be added to the device 10 to provide a magnified view of the
`patient’s eye 22 to the physician or user (see Figure 2). The fixed magnification of this
`lens would typically be chosen to between 1.5x and 15x. Typically the magnifications are
`
`
`
`“l
`
`a»
`
`

`

`between 2x and 10x. A variable focal length zoom lens could also be substituted as the
`
`simple magnifier to provide a range of magnification for the physician user.
`
`The invention described here can be manufactured as a stand-alone hand held device or
`incorporated into other ophthalmic diagnostic instruments such as a table—top or hand
`held slit lamp.
`
`Figure 2 shows an alternative system 100 of an ophthalmic illuminator constructed
`
`according to the invention. Figure 2 also shows the patient’s eye 102 illuminated by blue
`light 104 generated by the diode 106. The light 104 is preferably coupled to the eye 102
`through an optical lens (or reflector, known in the art) 108 to increase the blue light
`energy at the eye 102.
`
`System 100 preferably integrates to a common housing 110 such“ that a user can «hold the
`
`system 100 during treatment of the eye 102. Although I;
`hown, the circuit of Figure 1
`can reside within the housing 110; and a button 112 can be used to operate the switch 12
`(Figure 1) which in turn causes the generation of light 104. The button 112 is for example
`operated by a physician’s finger.
`
`I,
`
`System 100 can also include a magnifier 114 coupled to the housing 110 such that the
`
`physician’s eye 116 can view the patient’seye 102 with increased magnifier. A zoom
`
`lens (known in the art can replace the magnifier 114 such that selective control of that
`magnification is achieved.
`
`Figure 3 shows a hand held illuminator 200 constructed according to the invention.
`Illuminator 200 has an annular housing 202 that contains circuitry such as schematic 10
`
`of Figure l. A button 204 is arranged with housing 202 such that a user may press to
`
`generate light energy 206 to illuminate a patient‘s eye 208. Button 204 for example
`functions as switch 12, Figure l. A user of illuminator 200 may then peer through
`aperture 210, along path 212, to conveniently view patient eye 208. Aperture 210 may
`optionally include a magnifying lens, or zoom lens, according to preferred embodiments
`
`
`
`4R
`
`«4'
`
`

`

`of the invention. Sources for generating energy 206 include a LED such as LED 16,
`
`Figure 1. Sources may be integrated with housing 202 in various ways as illustrated
`
`below.
`
`In accord with the invention, energy 206 delivered from sources (e.g., LEDs)
`
`may be considered a transmit channel while path 212 may be considered a receive
`channel. 1n one embodiment of the invention, the energy is blue light that creates green
`fluorescence from the eye; and thus a lens in aperture 210 is preferably coated with a
`
`green filter thin film coating to filter light along the receive channel.
`
`Figure 4 shows a hand held illuminator 214 constructed according to the invention.
`
`llluminator 214 has an annular housing 216 that contains circuitry such as schematic 10
`of Figure 1. A button 218 is arranged with housing 216 such that a user may press to
`
`generate light energy 221 to illuminate a patient’s eye 217, as above. Eutton 218 for
`example functions as switch 12, Figure 1. Illuminator 214 further has an optical
`magnifier in the form of a lens 219 for a user to peer through to conveniently view patient,
`eye 217. A LED 220 integrates with housing 216 to generate light energy 218. LED 220
`may optionally include a focusing lens, though one is not required.
`
`Figure 5 shows an interior portion 222 of illuminator 21.4. Specifically, interior portion
`222 shows further features of button 218 and LED 220, each. connected in circuit to
`
`internal battery 224. Battery 224 for example operates as in battery 14, Figure 1, to power
`LED 220. Element 216a forms the back of housing‘216.
`
`
`
`ith housing 232 to generate light
`patient eye 236. A plurality of LEDs 238 integrate
`energy 234. Each of LEDs 238 may Optionally include a
`cusing lens, though one is not
`
`
`
`b
`
`1m
`
`

`

`required. Although
`
`departing from the scop
`
`
`LEDs 238 are shown, more or fewer LEDs can be used without
`
`e invention.
`
`
`Figure 7 shows an interior portion 240 of illuminator 230. Specifically, interior portion
`
`240 shows further features of button 234 and LEDs 238, each connected in circuit to
`
`internal battery 242. Battery 242 for example operates as in battery 14, Figure 1, to power
`
`LEDs 238. Element 232a forms the back of housing 232.
`
`In addition to the advantages apparent in the foregoing description, the invention may
`
`have application in other fields outside of ophthalmology. For example, in the field of
`
`dermatology, an illuminator of the invention may be used to illuminate skin, along the
`
`transmit channel, and to View the skin along the receive channel,
`
`In View of the foregoing, what is claimed is:
`
`
`
`a.
`
`

`

`
`
`1.
`
`An ophthalmic illuminator, comprising:
`
`a battery;
`
`an electrical resistor in circuit with the battery;
`
`an electrical switch in circuit with the resistor;
`
`at least one light emitting diode,
`
`in circuit with the switch, for generating blue light
`
`energy in response to activation of the switch; and
`
`a fluorescein dye administered to a patent’s eye, the dye being responsive to the energy to
`fluoresce.
`
`
`
`2.
`
`An illuminator of claim 1,
`
`further comprising an optical element disposed
`
`between the diode and the eye to increase blue light energy reaching the’eye.
`
`,
`
`V,
`
`An illuminator of claim 2, wherein the element is one of a lens or a poWered
`3.
`reflector.
`_V
`,
`7
`,.
`g
`‘
`,
`_
`,
`f-
`
`An illuminator of claim 1, further comprising electronics fOr cyclically energizing
`4.
`the diode, wherein the diode generates the blue light at a predetermined frequency in
`
`order to increase the illumination appearance of the energy.
`
`5.
`
`An illuminator of claim 1, further, comprising a housing for integrating the
`
`battery, switch, resistor and diode into an integral package, the diode being positioned to
`
`generate blue light energy away from the package, and further comprising a magnifier
`
`lens coupled to the housing for providing a magnified image of the patient’s eye to a user
`of the illuminator.
`
`An illuminator of claim 5, wherein the magnifier lens has a magnification
`6.
`between about 1.5X and 15X.
`
`7.
`
`An illuminator of claim 1, further comprising a housing for integrating the
`
`battery, switch, resistor and diode into an integral package, the diode being positioned to
`
`a
`
`.5»
`
`

`

`generate blue light energy away from the package, and further comprising a zoom lens
`
`coupled to the housing for providing a selective magnified image of the patient’s eye to a
`user of the illuminator.
`
`8.
`
`9.
`
`An illuminator of claim 1, wherein the dye comprises’Sodium Fluorescein.
`
`An illuminator of claim 1, wherein the diode comprises Gallium nitride.
`
`10.
`
`An illuminator of claim 1, wherein the diode comprises Silicon Carbide.
`
`
`
`An illuminator of claim 1, further comprising a substantially annular housing
`11.
`constructed and arranged with a button for operating the switch, a user of the illuminator
`
`viewing through an aperture in the housing to view the patient’s eye.
`
`An illuminatorcf claim 11,rfurther comprising a magmfying lens constructed
`12.
`and arranged with the aperture, for magnifying the patient’s eye for theus'er;
`4
`
`its
`
`An illuminator of claim ll, further, comprising a plurality of light emitting
`13.
`diodes, each diode responsive to activation by the button to generate the blue-light.
`
`An illuminator of claim 1, further comprising a focusing lens constructed and
`14.
`arranged with at least one of the diodes to focus the blue light energy onto the patient’s
`eye.
`
`15.
`
`A method for
`
`illuminating a patient’s eye for ophthalmic examination,
`
`comprising the steps of: administering a fluorescein dye to the patent’s eye, illuminating
`the eye with blue light energy generated from one or more light emitting diodes, the dye
`being responsive to the blue light energy to fluoresce, and viewing the patient’s eye, and
`viewing the eye while the dye fluoresces.
`
`us
`
`

`

`16.
`
`A method of claim 15, wherein the step of administering a fluorescein dye
`
`comprises administering Sodium Fluorescein to the eye.
`
`17.
`
`A method of claim 15, wherein the step of illuminating the eye comprises
`
`pressing a button on an annular-shaped housing, and wheiéin the step of Viewing the
`
`patient‘s eye comprises viewing through a center of the housing.
`
`18.
`
`A method of claim 15, wherein the step of illuminating comprises generating
`
`light from a plurality of light emitting diodes.
`
`19.
`
`A method of claim 15, wherein the step of Viewing comprises Viewing through a
`
`magnifying lens coupled with a housing that supports the diodes.
`
`20.
`
`A method of claim 15, further comprising the step of focusing the blue light
`
`energy onto the patient’ ”sceye.
`
`,.
`
`'
`
`--
`
`
`
`4‘
`
`

`

`Atty Docket No. 389841
`Express Mail Label No. EL656245460US
`
`
`PATENT
`
`COMBINED DECLARATION AND POWER OF ATTORNEY
`
`(ORIGINAL, DESIGN, NATIONAL STAGE OF PCT,
`SUPPLEMENTAL, DIVISIONAL, CONTINUATION OR CIP)
`
`As a below named inventor, I hereby declare that:
`
`TYPE OF DECLARATION
`
`This declaration is of the following type:
`
`X
`
`Continuation—impart
`
`INVENTORSHIP IDENTIFICATION
`
`
`
`My residence post office address and citizenship are as stated below nextto my name. I
`bel1eve I am the original, first and sole inventor (if only one name is listed below) or an original
`first and joint inventor (if plural names are listed below)of the subject matter which1s claimed
`and for which a patent is sought on the invention entitled:
`,
`,,
`,
`y
`>
`
`HAND HELD OPHTHALMIC ILUMINATORI
`
`J
`
`SPECIFICATION IDENTIFICATION
`
`The specification
`
`X
`
`is attached hereto.
`
`ACKNOWLEDGMENT OF REVIEW_ OF PAPERS AND DUTY OF CANDOR
`
`I hereby state that I have reviewed and understand the contents of the above-mentioned
`specification, including the claims, as amended by any amendment referred to above (if any).
`
`I acknowledge the duty to disclose all information known to me to be material to
`patentability of this application in accordance with Title 37, Code of Federal Regulations, § 1.56
`(a).
`
`and which is material to the examination of this application, namely, information where
`there is a substantial likelihood that a reasonable examiner would consider it important in
`deciding whether to allow the application to issue as a patent, and
`
`

`

`
`
`PATENT
`
`Atty Docket No. 389841
`Express Mail Label No. EL656245460US
`
`CLAIM FOR BENEFIT OF EARLIER U.S./PCT APPLICATION(S)
`UNDER 35 USC. 120
`
`I hereby claim the benefit under Title 35, United States ,Code,§ 120 of any United States
`application(s) or PCT international application(s) designating the United States of America that
`is/are listed below and, insofar as the subject matter of each of the claims of the application is not
`disclosed in that/those prior application(s) in the manner provided by the first paragraph of Title
`35, United States Code, § 112, I acknowledge the duty to disclose material information as
`defined in Title 37, Code of Federal Regulations, § 1.56(a) which occurred between the filing
`date of the prior application(s) and the national or PCT international filing date of this
`application.
`
`PRIOR U. S. APPLICATIONS OR PCT INTERNATIONAL APPLICATION(S)
`DESIGNATING THE U. S. FOR BENEFIT UNDER 35 USC 120
`
`U.S. APPLICATION(S)
`
`
`WPATENTEDA?PENDING ABANDONED
`US FILING DATE
`US APPLICATION(S)
`
`X 09/175 796 10/20/98 ' ‘
`
`
`
`
`
`
`STATUS (Check One)
`
`PRIORITY CLAIM
`
`I hereby claim foreign prion'ty benefits under Title 35 United States Code § 119 of any
`foreign application(s) for patent or inventor‘s certificate or of any PCT international application(s)
`designating at least one country other than the United States of America listed below and have also
`identified below any foreign application(s) for patent or inventor's certificate or any PCT
`international application(s) designating at least one country other than the United States of America
`filed by me on the same subject matter having a filing date before that of the application(s) of which
`priority is claimed.
`
`X
`
`No such applications have been filed.
`Such applications have been filed as follows.
`
`.1»
`
`

`

`
`
`PATENT
`
`‘ Atty Docket No. 389841
`Express Mail Label No. EL656245460US
`
`POWER OF ATTORNEY
`
`As a named inventor, I hereby appoint the following attorney(s) and/or agent(s) to prosecute
`this application and transact all business in the Patent and Trademark Office connected therewith:
`
`William A. Rudy, Reg. No. 34,916; Peter C. Knops, Reg. No. 37,659; Curtis A. Vock, Reg.
`No. 38,356; Dan Cleveland, Jr., Reg. No. 36,106, Thomas Swenson, Reg. No. 36,696; Patri