a2) United States Patent
`US 9,757,040 B2
`(0) Patent No.:
`*Sep. 12, 2017
`(45) Date of Patent:
`Islam
`
`US009757040B2
`
`SHORT-WAVE INFRARED
`SUPER-CONTINUUM LASERS FOR EARLY
`DETECTION OF DENTAL CARIES
`
`(56)
`
`References Cited
`U.S. PATENT DOCUMENTS
`
`(54)
`
`(71)
`
`(72)
`
`Applicant: OMNI MEDSCI, INC., Ann Arbor, MI
`(US)
`
`Inventor: Mohammed N.Islam, Ann Arbor, MI
`(US)
`
`(73)
`
`Assignee: Omni Medsci, Inc., Ann Arbor
`
`(*)
`
`Notice:
`
`Subject to any disclaimer, the term ofthis
`patent is extended or adjusted under 35
`U.S.C. 154(b) by 0 days.
`
`This patent is subject to a terminal dis-
`claimer.
`
`(21)
`
`Appl. No.: 15/357,136
`
`(22)
`
`Filed:
`
`Nov. 21, 2016
`
`(65)
`
`(63)
`
`Prior Publication Data
`
`US 2017/0071474 Al
`
`Mar. 16, 2017
`
`Related U.S. Application Data
`
`Continuation of application No. 14/651,367, filed as
`application No. PCT/US2013/075736 on Dec. 17,
`2013, now Pat. No. 9,500,635.
`(Continued)
`
`(51)
`
`Int. Cl.
`
`GOLF 3/00
`AG6IB 5/00
`
`(52)
`
`USS. Cl.
`
`(2006.01)
`(2006.01)
`(Continued)
`
`CPC we AG6IB 5/0088 (2013.01); A6IB 5/0013
`(2013.01); A6IB 5/0022 (2013.01);
`(Continued)
`Field of Classification Search
`CPC ...... GO1J 3/02; GO1J 3/28; GO1J 3/42; GOIN
`21/31
`
`(58)
`
`4,063,106 A
`4,158,750 A
`
`12/1977 Ashkin etal.
`6/1979 Sakoeet al.
`(Continued)
`
`FOREIGN PATENT DOCUMENTS
`
`CN
`DE
`
`101849821 B
`102010012987 Al
`
`7/2013
`10/2010
`
`(Continued)
`
`OTHER PUBLICATIONS
`
`Pan, Yingtian, et al., “Hand-held arthroscopic optical coherence
`tomography for in vivo high-resolution imaging of articular carti-
`lage”, Journal of Biomedical Optics 8(4), Oct. 2003, pp. 648-654.
`(Continued)
`
`Primary Examiner — Tarifur Chowdhury
`Assistant Examiner — Md M Rahman
`
`(74) Attorney, Agent, or Firm — Brooks Kushman P.C.
`
`(57)
`
`ABSTRACT
`
`A wearable device for use with a smart phone or tablet
`includes a measurement device having a plurality of LEDs
`generating a near-infrared input optical beam that measures
`physiological parameters. The measurement device includes
`lenses configured to receive andto deliver the input beam to
`skin which reflects the beam. The measurement device
`
`includesa reflective surface configured to receive and redi-
`rect the light from the skin, and a receiver configured to
`receive the reflected beam. The light source is configured to
`increase a signal-to-noise ratio of the input beam reflected
`from the skin by increasing thelight intensity from the LEDs
`and modulation of the LEDs. The measurement device is
`configured to generate an output signal representing a non-
`invasive measurement on blood contained within the skin.
`The wearable device is configured to wirelessly communi-
`cate with the smart phone or tablet which receives and
`processes the output signal.
`
`(Continued)
`
`10 Claims, 16 Drawing Sheets
`
`1270
`
`
`
` 4276
`>PUTST| 1277}
`
`/
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`f
`é
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`}
`
`| MONOCHROMATOR|{ been}
`
`
`SHIT}
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`|_
`iS DETECTOR®
`PRE-AMP
`QUIPLT
`L ANPURIER |
`
`Page 1
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`OMNI 2003 - IPR20-00209
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`Page 1
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`OMNI 2003 - IPR20-00209
`
`

`

`US 9,757,040 B2
`
`Page 2
`
`Related U.S. Application Data
`(60) Provisional application No. 61/747,477,filed on Dec.
`31, 2012, provisional application No. 61/754,698,
`filed on Jan. 21, 2013.
`
`(51)
`
`(52)
`
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2014.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2014.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`
`Int. Cl.
`A61B 5/1455
`GOLJ 3/10
`GO1J 3/28
`GOLJ 3/453
`GOIN 21/359
`AGIB 5/145
`GOIN 33/15
`GOIN 33/49
`GOIN 21/3563
`GOIN 21/39
`GOIN 33/02
`GOIN 33/44
`GOIN 21/88
`HOIS 3/30
`GOLJ 3/14
`GOLJ 3/18
`GOIM 3/38
`US. Cl.
`CPC veeeescees AGIB 5/0075 (2013.01); A61B 5/0086
`(2013.01); A61B 5/1455 (2013.01); A61B
`5/14532 (2013.01); A61B 5/14546 (2013.01);
`AGIB 5/4547 (2013.01); GOLJ 3/108
`(2013.01); GO1J 3/28 (2013.01); GOLJ 3/2823
`(2013.01); GOL 3/453 (2013.01); GOIN
`21/359 (2013.01); GOIN 21/3563 (2013.01);
`GOIN 21/39 (2013.01); GOIN 21/88
`(2013.01); GOIN 33/02 (2013.01); GOIN
`33/15 (2013.01); GOIN 33/442 (2013.01);
`GOIN 33/49 (2013.01); A61B 2562/0233
`(2013.01); A61B 2562/0238 (2013.01); AGIB
`2562/146 (2013.01); A6IB 2576/02 (2013.01);
`GOLJ 3/14 (2013.01); GOIJ 3/1838 (2013.01);
`GOLJ 2003/104 (2013.01); GOLT 2003/2826
`(2013.01); GOIM 3/38 (2013.01); GOIN
`2021/399 (2013.01); GOIN 2201/061
`(2013.01); GOIN 2201/062 (2013.01); GOIN
`2201/08 (2013.01); GOIN 2201/12 (2013.01);
`HO1S 3/302 (2013.01)
`(58) Field of Classification Search
`USPC coecccsesssessssesseseessrecsssessnesseseesseeecanecssne 356/300
`See application file for complete search history.
`.
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`
`Page 2
`
`OMNI 2003 - IPR20-00209
`
`

`

`US 9,757,040 B2
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