US009651533B2
`
`a2) United States Patent
`US 9,651,533 B2
`(0) Patent No.:
`*May 16, 2017
`(45) Date of Patent:
`Islam
`
`(54)
`
`(71)
`
`(72)
`
`SHORT-WAVE INFRARED
`SUPER-CONTINUUM LASERS FOR
`DETECTING COUNTERFEIT OR ILLICIT
`DRUGS AND PHARMACEUTICAL PROCESS
`CONTROL
`
`Applicant: OMNI MEDSCI, INC., Ann Arbor, MI
`(US)
`
`Inventor:
`
`MohammedN.Islam, Ann Arbor, MI
`(US)
`
`(58) Field of Classification Search
`CPC ....... GOIN 33/15; GOIN 21/359; GOIN 33/49
`(Continued)
`
`(56)
`
`References Cited
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`(Continued)
`
`FOREIGN PATENT DOCUMENTS
`
`(73)
`
`Assignee:
`
`Omni Medsci, Inc., Ann Arbor, MI
`(US)
`
`CN
`DE
`
`101849821 B
`102010012987 Al
`
`7/2013
`10/2010
`
`(*)
`
`Notice:
`
`Subject to any disclaimer, the term ofthis
`patent is extended or adjusted under 35
`U.S.C. 154(b) by 0 days.
`
`This patent is subject to a terminal dis-
`claimer.
`
`(21)
`
`Appl. No.: 14/875,709
`
`(22)
`
`Filed:
`
`Oct. 6, 2015
`
`(Continued)
`
`OTHER PUBLICATIONS
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`Istepanian, Robert H., “The Comparative Performance of Mobile
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`(Continued)
`
`(65)
`
`(63)
`
`(51)
`
`(52)
`
`Prior Publication Data
`
`Primary Examiner — David Porta
`Assistant Examiner — Abra Fein
`
`US 2016/0047787 Al
`
`Feb. 18, 2016
`
`(74) Attorney, Agent, or Firm — Brooks Kushman P.C.
`
`Related U.S. Application Data
`
`Continuation of application No. 14/108,986, filed on
`Dec. 17, 2013, now Pat. No. 9,164,032.
`(Continued)
`
`(2006.01)
`(2006.01)
`(Continued)
`
`Int. Cl.
`GOLT 5/20
`GOIN 33/15
`US. Cl.
`CPC wee GOIN 33/15 (2013.01); A61B 5/0013
`(2013.01); A61B 5/0022 (2013.01);
`(Continued)
`
`(57)
`
`ABSTRACT
`
`A measurement system includes a wearable measurement
`device for measuring one or more physiological parameters,
`including a light source comprising a plurality of light
`emitting diodes (LEDs) configured to generate an output
`optical beam with a near-infrared wavelength between 700
`nanometers and 2500 nanometers. The light source is con-
`figured to increase signal-to-noise ratio by increasing a light
`intensity and pulse rate of the LEDs. The system includes a
`plurality of lenses configured to receive the output optical
`beam and to deliver an analysis output beam to a sample.
`The wearable measurement device includes a receiver con-
`figured to process the analysis output beam reflected or
`transmitted from the sample and to generate an output signal
`(Continued)
`
`1800
`
`1804
`1802
`1806
`ba
`.
`CHOPPER
`1808
`ne Fs
`
`
`
`
`
`/ a SAMPLE DETECTOR+
`
`
`
`
`
`=<]
`SCSOURCE
`MONOCHROMATOR
`SK
`SAMPLE Ky PRE-AMP(MCT}
`
`
`
`
`
`
`1807
`REFERENCE DETECTOR
`
`DN
`REFERENCE ph + PRE-ANP(CT
`/1809
`
`
`
`
`
`
`
`
`+————|_LOCK-IN AMP #2
`
`
`
`
`
`
`
`
`COMPUTER
`
`/
`1814
`
`Page 1
`
`OMNI 2004 - IPR20-00209
`
`1840
`
`Page 1
`
`OMNI 2004 - IPR20-00209
`
`

`

`US 9,651,533 B2
`
`Page 2
`
`PPPPPEErEEEEEPEPSEPPPEEPPEPEEPEPEPPPEEPS
`
`that may be transmitted to a remote device configured to
`process the received output status to generate processed data
`and to store the processed data.
`
`18 Claims, 26 Drawing Sheets
`
`Related U.S. Application Data
`
`(60) Provisional application No. 61/747,487,filed on Dec.
`31, 2012.
`
`(51)
`
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2014.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`(2006.01)
`
`Int. Cl.
`AGIB 5/1455
`AG6IB 5/00
`GOLF 3/10
`GOLJ 3/28
`GOLS 3/453
`GOIN 21/359
`AGIB 5/145
`GOIN 33/49
`HOIS 3/30
`GOLS 3/14
`GOLS 3/18
`(52) U.S. Cl.
`CPC we AG6IB 5/0075 (2013.01); A6IB 5/0086
`(2013.01); A61B 5/0088 (2013.01); A6IB
`5/1455 (2013.01); A6IB 5/14532 (2013.01):
`AGIB 5/14546 (2013.01); AGIB 5/4547
`(2013.01); GOLF 3/108 (2013.01); GOLT 3/28
`(2013.01); GOLT 3/453 (2013.01); GOIN
`21/359 (2013.01); GOIN 33/49 (2013.01):
`AGIB 2562/0233 (2013.01); A6IB 2562/0238
`(2013.01); A61B 2562/146 (2013.01); A61B
`2576/02 (2013.01); GOLJ 3/14 (2013.01);
`GOLJ 3/1838 (2013.01); GOLT 2003/104
`(2013.01); GOLJ 2003/2826 (2013.01); GOIN
`2201/061 (2013.01); GOIN 2201/062
`(2013.01); GOIN 2201/12 (2013.01); HOS
`3/302 (2013.01)
`
`(58) Field of Classification Search
`USPC iceccsesssesctessseescseecessescsenssansenseeees 250/338.4
`See application file for complete search history.
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`
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`
`OMNI 2004 - IPR20-00209
`
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