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`Supercell
`Exhibit 1036
`Page 3
`
`
`
`
`" #
`
`Supercell
`Exhibit 1036
`Page 3
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`Supercell
`Exhibit 1036
`Page 4
`
`
`" "
`
`
`Supercell
`Exhibit 1036
`Page 4
`
`
`
`2/8/2021
`
`
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`The new coronavirus variant
`The new variant of the virus that causes COVlD-lg has several
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`mutations on its spike proteins. These spikes are used by the
`virus to attach to and infect cells. The spikes also are what
`vaccines and antibody drugs target.
`
`
`
`New coronavirus variant could take over by spring, experts say
`
`Spike protein
`
`
`
`
`
`Host cell
`
`Envelope
`
`(person)
`Membrane
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`attach to host and
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`protein
`virus replicates
`
`inside cell
`
`
`
`.
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`
`
`
`Genomic RNA is a complete
`set of genetic instructions
`written in 30,000 "letters” of
`
`code. Different sections of the
`genome guide how different
`parts of the virus are
`constructed when the virus
`
`replicates in host cells.
`
`think mutations
`
`The result
`
`in spike proteins Variant virus
`allow virus to
`seems to be
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`Other
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`SOURCE: The Associated Press, Reuters, Dal/as Morning News reporting
`
`Carol Zuber-Mallison/Staff Artist
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`
`The new coronavirus variant
`The new variant of the virus that causes COVlD-lg has several
`
`mutations on its spike proteins. These spikes are used by the
`virus to attach to and infect cells. The spikes also are what
`vaccines and antibody drugs target.
`
`
`
`New coronavirus variant could take over by spring, experts say
`
`Spike protein
`
`
`
`
`
`Host cell
`
`Envelope
`
`(person)
`Membrane
`Protein spikes
`protein
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`Envelope
`attach to host and
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`protein
`virus replicates
`
`inside cell
`
`
`
`.
`ill
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`
`
`
`Genomic RNA is a complete
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`written in 30,000 "letters” of
`
`code. Different sections of the
`genome guide how different
`parts of the virus are
`constructed when the virus
`
`replicates in host cells.
`
`think mutations
`
`The result
`
`in spike proteins Variant virus
`allow virus to
`seems to be
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`
`®
`
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`The genome
`
`-
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`I
`
`I
`
`I
`
`I I II
`
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`
`
`
`I
`
`Other
`structural proteins
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`Non-structural proteins
`Regulate other aspects Allow virus to attach Used for envelope,
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`to healthy cells
`membrane, etc.
`SOURCE: The Associated Press, Reuters, Dal/as Morning News reporting
`
`Carol Zuber-Mallison/Staff Artist
`
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`Some say the US. likely has its own, more contagious homegrown variants. But the US. hasn’t done as much
`
`genetic analysis of virus samples as some other countries.
`
`https://www.dallasnews.com/news/2021/01/16/new-coronavirus—variant-could-take-over-by-spring-experts-say/
`
`5/14
`
`" #
`
`Page 5
`
`Supercell
`Exhibit 1036
`
`Supercell
`Exhibit 1036
`Page 5
`
`
`
`
`Some say the US. likely has its own, more contagious homegrown variants. But the US. hasn’t done as much
`
`genetic analysis of virus samples as some other countries.
`
`https://www.dallasnews.com/news/2021/01/16/new-coronavirus—variant-could-take-over-by-spring-experts-say/
`
`5/14
`
`" #
`
`Page 5
`
`Supercell
`Exhibit 1036
`
`Supercell
`Exhibit 1036
`Page 5
`
`
`
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`! !
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`Supercell
`Exhibit 1036
`Page 6
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` "
`
`Supercell
`Exhibit 1036
`Page 6
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`
`
`2/8/2021
`
`New coronavirus variant could take over by spring, experts say
`
`SARS-CoV-Z variants of concern
`
`ÿ
`
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`
`Scientists are concerned about the spread of corona
`
`these different genome sequences.
`
`September 2020—Tuesday
`
`Variant
`
`First
`identified
`
`Current sequence-
`confirmed cases
`
`United
`
`States Worldwide
`
`8.1.1.7
`
`United Kingdom
`
`88*
`
`15,369
`
`September 2020
`
`8.1.351
`
`South Africa
`
`October 2020
`
`P1
`
`Brazil and Japan
`
`January 2021
`
`0
`
`0
`
`415
`
`35
`
`COVlD-19 B.1.1.7 variant in the U.S
`
`The cases are based on a sampling of SARS—CoV-2-
`
`specimens and do not represent the total number 0
`
`lineage cases that may be circulating. In Texas, sing
`have been confirmed in Dallas and Harris counties.
`
`1 case I 2-5 cases
`
` *U.S. case count as of Friday;
`
`
`
`
`Scientists are concerned about the spread of corona
`
`these different genome sequences.
`
`September 2020—Tuesday
`
`Variant
`
`First
`identified
`
`Current sequence-
`confirmed cases
`
`United
`
`States Worldwide
`
`8.1.1.7
`
`United Kingdom
`
`88*
`
`15,369
`
`September 2020
`
`8.1.351
`
`South Africa
`
`October 2020
`
`P1
`
`Brazil and Japan
`
`January 2021
`
`0
`
`0
`
`415
`
`35
`
`COVlD-19 B.1.1.7 variant in the U.S
`
`The cases are based on a sampling of SARS—CoV-2-
`
`specimens and do not represent the total number 0
`
`lineage cases that may be circulating. In Texas, sing
`have been confirmed in Dallas and Harris counties.
`
`1 case I 2-5 cases
`
` *U.S. case count as of Friday;
`
`
!
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`
`
!
!
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`
`
`Immunization and Respiratory Diseases,
`Division of Viral Diseases
`https://www.dallasnews.com/news/2021/01/16/new-coronavirus—variant—could-take-over-by-spring-experts-say/
`
`other totars as of Tuesday.
`
`SOURCE: National Center for
`
`" #
`
`7/14
`
`Supercell
`Exhibit 1036
`
`Page 7
`
`Supercell
`Exhibit 1036
`Page 7
`
`
`
`
`
`Immunization and Respiratory Diseases,
`Division of Viral Diseases
`https://www.dallasnews.com/news/2021/01/16/new-coronavirus—variant—could-take-over-by-spring-experts-say/
`
`other totars as of Tuesday.
`
`SOURCE: National Center for
`
`" #
`
`7/14
`
`Supercell
`Exhibit 1036
`
`Page 7
`
`Supercell
`Exhibit 1036
`Page 7
`
`
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` "
`
`Supercell
`Exhibit 1036
`Page 8
`
`
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` "
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`Supercell
`Exhibit 1036
`Page 8
`
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