US007905833B2
`
`a2) United States Patent
`US 7,905,833 B2
`(0) Patent No.:
`Mar. 15, 2011
`(45) Date of Patent:
`Brister et al.
`
`(54) TRANSCUTANEOUS ANALYTE SENSOR
`
`(56)
`
`References Cited
`
`(75)
`
`Inventors: Mark Brister, Encinitas, CA (US);
`Steve Masterson, Encinitas, CA (US); J.
`MichaelDobbles, San Clemente, CA
`(US); Michael Robert Mensinger, San
`Diego, CA (US); Sean Saint, San Diego,
`CA (US); Apurv Ullas Kamath, San
`Diego, CA (US); James Brauker,
`Addison, MI (US); James Patrick
`Thrower, Oakland, NJ (US)
`
`(73) Assignee: DexCom,Inc., San Diego, CA (US)
`(*) Notice:
`Subject to any disclaimer, the term ofthis
`patent is extended or adjusted under 35
`U.S.C. 154(b) by 713 days.
`
`(21) Appl. No.: 11/157,365
`.
`Filed:
`
`(22)
`(65)
`
`Jun. 21, 2005
`Prior Publication Data
`US 2006/0036144 Al
`Feb. 16, 2006
`Related U.S. Application Data
`(60) Provisional application No. 60/614,764,filed on Sep.
`30, 2004, provisional application No. 60/614,683,
`filed on Sep. 30, 2004, provisional application No.
`60/587,787,
`filed on Jul.
`13, 2004, provisional
`application No. 60/587,800,filed on Jul. 13, 2004.
`
`(51)
`
`Int. Cl.
`(2006.01)
`AGIB 5/00
`(2006.01)
`AGIB 5/05
`(52) U.S.CL ......... 600/309; 600/345; 600/347; 600/365
`(58) Field of Classification Search .................. 600/347,
`600/365
`See application file for complete search history.
`
`10.
`
`~ 76.
`
`14:
`
`U.S. PATENT DOCUMENTS
`1.564.641 A
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`:
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`OTHER PUBLICATIONS
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`
`(Continued)
`:
`..
`.
`.
`Primary Examiner — Patricia C Mallari
`(74) Attorney, Agent, or Firm — Knobbe Martens Olson &
`Bear LLP
`
`ABSTRACT
`(57)
`The present invention relates generally to systems and meth-
`ods for measuring an analyte in a host. Moreparticularly, the
`present inventionrelates to systems and methodsfor transcu-
`taneous measurementofglucose in a host.
`
`17 Claims, 30 Drawing Sheets
`
`
`
`ABBOTT DIABETES CAREINC.
`IPR2022-00914
`Exhibit 1011 - Page 1 of 93
`
`ABBOTT DIABETES CARE INC.
`IPR2022-00914
`Exhibit 1011 - Page 1 of 93
`
`

`

`US 7,905,833 B2
`
`Page 2
`
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`PPPPPEEEPEEPSEEEEESEPSESPEEEMEPSESESEMPLEESESEEEEEPEESPPEEPPEESESEPEEPPEeePPEe
`
`5,372,719PPPPrSEESSEPEPSEEEEESEPEESEEEEEPSESPEEEPPEPEEPSEEEEPPEESEPEEPEPEEESEEEEPPEEE
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`4,883,057
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`
`ABBOTT DIABETES CAREINC.
`IPR2022-00914
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`ABBOTT DIABETES CARE INC.
`IPR2022-00914
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`

`US 7,905,833 B2
`
`Page 3
`
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`
`ABBOTT DIABETES CAREINC.
`IPR2022-00914
`Exhibit 1011 - Page 3 of 93
`
`ABBOTT DIABETES CARE INC.
`IPR2022-00914
`Exhibit 1011 - Page 3 of 93
`
`

`

`US 7,905,833 B2
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`
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`6,477,395 B2
`9/2000 Wongetal.
`6,123,827 A
`11/2002 Holkeret al.
`6,484,045 Bl
`10/2000 Sayetal.
`6,134,461 A
`11/2002 Say etal.
`6,484,046 Bl
`10/2000 Houbenetal.
`6,135,978 A
`12/2002 Schulman etal.
`6,498,043 Bl
`11/2000 Berneretal.
`6,144,869 A
`12/2002 Jackson
`6,498,941 Bl
`11/2000 Saito etal.
`6,144,871 A
`1/2003 Heckel
`6,510,239 Bl
`12/2000 Heller et al.
`6,162,611 A
`1/2003 Heckel
`6,510,329 B2
`1/2001 Gavriely
`6,168,568 Bl
`1/2003 Colvinet al.
`6,512,939 Bl
`1/2001 Alvarez etal.
`6,169,155 Bl
`2/2003 Helleretal.
`6,514,718 B2
`1/2001 Sayetal. we, 600/345
`6,175,752 B1*
`2/2003 Mcivoretal.
`6,520,326 B2
`1/2001 Kurniket al.
`6,180,416 Bl
`2/2003 Pekkarinenetal.
`6,520,997 Bl
`2/2001 Oweiset al.
`6,187,062 Bl
`2/2003 Khalil et al.
`6,526,298 Bl
`3/2001 Darrowetal.
`6,201,980 Bl
`3/2003 Turcott
`6,527,729 Bl
`3/2001 Kruse etal.
`6,201,993 Bl
`3/2003 Pollack
`6,534,711 Bl
`3/2001 Schulman etal.
`6,208,894 Bl
`3/2003 Ita et al.
`6,537,318 Bl
`4/2001 Ward et al.
`6,212,416 Bl
`4/2003 Zhong etal.
`6,541,107 Bl
`4/2001 Robinson
`6,212,424 Bl
`4/2003 Galley et al.
`6,544,212 B2
`4/2001 Offenbacheret al.
`6,214,185 Bl
`4/2003 Kilgour etal.
`6,545,085 B2
`4/2001 Cormieretal.
`6,219,574 Bl
`4/2003 Ishikawaetal.
`6,546,268 Bl
`4/2001 Rosar
`6,223,083 Bl
`4/2003 Kurnik
`6,546,269 Bl
`5/2001 Duffin
`6,230,059 Bl
`4/2003 Zhanget al.
`6,547,839 B2
`5/2001 Lietal.
`6,231,879 Bl
`4/2003 Molesetal.
`6,551,496 Bl
`5/2001 Merrill
`6,232,783 Bl
`4/2003 Mannheimeretal. ........ 600/323
`6,553,241 B2*
`§/2001 Brenneretal.
`6,233,080 Bl
`4/2003 Leshoetal.
`6,553,244 B2
`§/2001 Berneret al.
`6,233,471 Bl
`5/2003 Causey
`6,558,320 Bl
`6/2001 Causey,III etal.
`6,248,067 Bl
`5/2003 Burdet al.
`6,558,321 Bl
`6/2001 Daietal.
`6,251,280 Bl
`5/2003 Steil et al.
`6,558,351 Bl
`7/2001 Schultz
`6,256,522 Bl
`5/2003 Helleretal. ou. 600/347
`6,560,471 B1*
`7/2001 Schulman etal.
`6,259,937 Bl
`5/2003 Conn etal.
`6,561,978 Bl
`7/2001 Blackburn et al.
`6,264,825 Bl
`5/2003 Say etal.
`6,565,509 Bl
`7/2001 Han et al.
`6,268,161 Bl
`5/2003 Otsuka etal.
`6,569,309 B2
`8/2001 Kurnik
`6,272,364 Bl
`6/2003 Knobbeetal.
`6,572,545 B2
`8/2001 Trespetal.
`6,272,480 Bl
`6/2003 Abbinketal.
`6,574,490 B2
`8/2001 Grieset al.
`6,274,285 Bl
`6/2003 Knobbeetal.
`6,575,905 B2
`8/2001 Mosbachetal.
`6,274,686 Bl
`6/2003 Eglise
`6,579,498 Bl
`8/2001 Grossetal. we 600/345
`6,275,717 B1*
`6/2003 Bonnecazeet al.
`6,579,690 BI
`9/2001 Heller et al.
`6,284,478 Bl
`7/2003 Lebel etal.
`6,585,644 B2
`9/2001 Safabash etal.
`6,293,925 Bl
`7/2003 Connelly etal.
`6,589,229 Bl
`9/2001 Heller
`6,294,281 Bl
`7/2003 Buseet al.
`6,591,125 Bl
`10/2001 Kurnik et al.
`6,299,578 Bl
`7/2003 Berneretal.
`6,595,919 B2
`10/2001 Webb et al.
`6,300,002 Bl
`8/2003 Struyset al.
`6,605,072 B2
`10/2001 Knobbeet al.
`6,302,855 Bl
`9/2003 Kerr
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`10/2001 Kurnik et al.
`6,309,351 Bl
`9/2003 Ward etal.
`6,613,379 B2
`10/2001 Harrington etal.
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`9/2003 Feldman et al.
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`10/2001 Cooperet al.
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`10/2003 Fordet al.
`6,633,772 B2
`10/2001 Markowitz et al.
`6,310,110 Bl
`
`6,315,738 Bl=11/2001 Nishikawaet al. 6,641,533 B2 11/2003 Causeyetal.
`
`6,319,566 Bl
`11/2001 Polanyiet al.
`6,642,015 B2
`11/2003 Vachonetal.
`6,325,978 Bl
`12/2001 Labuda et al.
`6,645,181 Bl
`11/2003 Lavi et al.
`6,325,979 Bl
`12/2001 Hahnetal.
`6,654,625 Bl
`11/2003 Say etal.
`6,326,160 Bl
`12/2001 Dunnetal.
`6,673,596 Bl
`1/2004 Sayleretal.
`6,329,161 Bl
`12/2001 Helleretal.
`6,689,265 B2
`2/2004 Heller etal.
`6,329,929 Bl
`12/2001 Weijand etal.
`6,695,860 Bl
`2/2004 Ward etal.
`6,330,464 Bl
`12/2001 Colvin,Jr. etal.
`6,699,383 B2
`3/2004 Lemire etal.
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`1/2002 Clark, Jr.
`6,702,857 B2
`3/2004 Braukeretal.
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`3/2002 Berneretal.
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`3/2004 Markle
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`3/2002 Melveret al.
`6,705,833 B2
`3/2004 Tam etal.
`6,365,670 Bl
`4/2002 Fry
`6,721,587 B2
`4/2004 Gough
`6,366,794 Bl
`4/2002 Moussyetal.
`6,730,200 Bl
`5/2004 Stewart et al.
`6,368,141 Bl
`4/2002 VanAntwerpetal.
`6,733,655 Bl
`5/2004 Davieset al.
`6,368,274 Bl
`4/2002 Van Antwerp etal.
`6,737,158 Bl
`5/2004 Thompson
`6,370,941 B2
`4/2002 Nakamuraetal.
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`5/2004 Shultset al.
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`4/2002 Worthingtonetal.
`6,742,635 B2
`6/2004 Neelet al.
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`4/2002 Kintzig et al.
`6,773,565 B2
`8/2004 Kunimotoet al.
`6,379,883 B2
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`6,801,041 B2
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`6/2002 Essenpreiset al.
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`10/2004 Jungetal.
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`6/2002 Uegane
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`10/2004 Mann etal.
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`7/2002 Miller
`6,815,186 B2
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`6,862,465 B2
`3/2005 Shults et al.
`6,424,847 B1*
`7/2002 Mastrototaroetal. ........ 600/316
`6,869,413 B2
`3/2005 Langley etal.
`6,447,448 Bl
`9/2002 Ishikawaetal.
`6,875,386 Bl
`4/2005 Ward et al.
`6,447,542 Bl
`9/2002 Weadock
`6,891,317 B2
`5/2005 Pei etal.
`6,459,917 Bl
`10/2002 Gowdaetal.
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`10/2002 Feldman etal.
`6,893,552 Bl
`5/2005 Wanget al.
`
`ABBOTT DIABETES CAREINC.
`IPR2022-00914
`Exhibit 1011 - Page 4 of 93
`
`ABBOTT DIABETES CARE INC.
`IPR2022-00914
`Exhibit 1011 - Page 4 of 93
`
`

`

`US 7,905,833 B2
`
`Page 5
`
`12/2002 Boerensteinetal.
`2002/0182241 Al
`5/2005 Shin etal.
`6,895,263 B2
`
`
`6,925,393 Bl 2002/0188185 Al=12/2002 Sohrab8/2005 Kalatz etal.
`6,931,327 B2
`8/2005 Goodeetal.
`2002/0188216 Al
`12/2002 Kayyali et al.
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`2002/0193885 Al
`12/2002 Legeayet al.
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`11/2005 Hitchcock etal.
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`12/2002 Lebeletal.
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`6,972,080 Bl=12/2005 Tomiokaetal. 2003/0004457 Al 1/2003 Andersson
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`2/2006 Monfreetal.
`2003/0006669 Al
`1/2003 Pei et al.
`7,003,336 B2
`2/2006 Holkeretal.
`2003/0023171 Al
`1/2003 Sato etal.
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`1/2003 Braukeretal.
`7,011,630 B2
`3/2006 Desaietal.
`2003/0028089 Al
`2/2003 Galley etal.
`7,025,743 B2
`4/2006 Mannet al.
`2003/0032874 Al
`2/2003 Rhodesetal.
`7,058,437 B2
`6/2006 Buse etal.
`2003/0036773 Al
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`6/2006 Keith et al.
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`7,070,580 B2
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`2003/0065254 Al
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`7,074,307 B2
`7/2006 Simpsonetal.
`2003/0070548 Al
`4/2003 Clausen
`7,078,582 B2
`7/2006 Stebbingsetal.
`2003/0078481 Al
`4/2003 Mclvoretal.
`7,081,195 B2
`7/2006 Simpsonetal.
`2003/0078560 Al
`4/2003 Miller et al.
`7,098,803 B2
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`2003/0097082 Al
`5/2003 Purdy et al.
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`7,134,999 B2
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`12/2006 Vachon
`2003/0125613 Al
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`1/2007 Schulein etal.
`2003/0130616 Al
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`7,190,988 B2
`3/2007 Say et al.
`2003/0134347 Al
`7/2003 Helleretal.
`7,207,974 B2
`4/2007 Safabashetal.
`2003/0138674 Al
`7/2003 Zeikusetal.
`7,225,535 B2
`6/2007 Feldman etal.
`2003/0181794 Al
`9/2003 Rini etal.
`7,267,665 B2
`9/2007 Steil etal.
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`2003/0200040 Al
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`7,310,544 B2
`12/2007 Bristeretal.
`2003/0203498 Al
`10/2003 Neeletal.
`7,344,499 Bl
`3/2008 Prausnitz etal.
`2003/0211625 Al
`11/2003 Cohan etal.
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`4/2008 Steil et al.
`2003/0212317 Al
`11/2003 Kovatchevetal.
`7,366,566 B2
`4/2008 Bristeretal.
`2003/0212346 Al
`11/2003 Yuzhakovetal.
`7,381,184 B2
`6/2008 Funderburk etal.
`2003/0212347 Al
`11/2003 Sohrab
`7,399,277 B2
`7/2008 Saidaraetal.
`2003/0217966 Al
`11/2003 Tapsak etal.
`7,402,153 B2
`7/2008 Steil etal.
`2003/0225437 Al
`12/2003 Ferguson
`7,417,164 B2
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`12/2003 Bartkowiak etal.
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`9/2008 Bristeretal.
`2004/0011671 Al
`1/2004 Shults etal.
`7,426,408 B2
`9/2008 DeNuzzio etal.
`2004/0015063 Al
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`12/2008 Bristeretal.
`2004/0015134 Al
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`7,467,003 B2
`12/2008 Bristeretal.
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`2/2004 Brodnick
`7A7T1,972 B2
`12/2008 Rhodesetal.
`2004/0030285 Al
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`7,494,465 B2
`2/2009 Bristeretal.
`2004/0039298 Al
`2/2004 Abreu
`7,497,827 B2
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`10/2002 Koulik
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`
`ABBOTT DIABETES CAREINC.
`IPR2022-00914
`Exhibit 1011 - Page 5 of 93
`
`ABBOTT DIABETES CARE INC.
`IPR2022-00914
`Exhibit 1011 - Page 5 of 93
`
`

`

`US 7,905,833 B2
`
`Page 6
`
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`
`ABBOTT DIABETES CAREINC.
`IPR2022-00914
`Exhibit 1011 - Page 6 of 93
`
`ABBOTT DIABETES CARE INC.
`IPR2022-00914
`Exhibit 1011 - Page 6 of 93
`
`

`

`US 7,905,833 B2
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`Wo
`Wo
`Wo
`Wo
`Wo
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`Wo
`Wo
`Wo
`Wo
`Wo
`Wo
`Wo
`WO
`WO
`WO
`WO
`wo
`Wo
`WO
`Wo
`WO
`Wo
`Wo
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`1/1997
`WO 97/01986
`2/1997
`WO 97/06727
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`WO 97/28737
`5/1998
`WO 98/19159
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`WO 98/24358
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`WO 98/38906
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`WO 00/59373
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`WO 00/074753
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`WO 01/00865
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`WO 01/12158
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`WO 01/20019 A2
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`WO 01/88534
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`WO 02/082989
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`WO 02/100266
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`WO 03/033726
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`WO 03/082091
`2/2005
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