Material Safety Data Sheet
`
`S0163
`
`HAZARD WARNINGS
`
`RISK PHRASES
`
`PROTECTIVE CLOTHING
`
`Irritating to skin, eyes, and the respiratory system.
`POSSIBLE CARCINOGEN. MINIMIZE EXPOSURE.
`
`Section I.
`
`Chemical Product and Company Identification
`
`Chemical Name
`
`Stearic Acid
`
`Catalog Number
`
`S0163
`
`Synonym
`
`Cetylacetic Acid
`
`Chemical Formula
`
`CH3(CH2)16COOH
`
`CAS Number
`
`57-11-4
`
`Supplier
`
`TCI America
`9211 N. Harborgate St.
`Portland OR
`1-800-423-8616
`
`In case of
`Emergency
`Call
`
`Chemtrec®
`(800) 424-9300 (U.S.)
`(703) 527-3887 (International)
`
`Section II.
`
`Chemical Name
`
`Composition and Information on Ingredients
`Percent (%)
`TLV/PEL
`
`CAS Number
`
`Toxicology Data
`
`Stearic Acid
`
`57-11-4
`
`Min. 95.0
`(GC)
`
`This chemical is classified as
`a possible carcinogen. There
`is no acceptable exposure limit
`for a carcinogen.
`
`Rat LD50 (intravenous) 21500
`ug/kg
`Mouse LD50 (intravenous) 23000
`mg/kg
`
`Section III.
`
`Hazards Identification
`
`Acute Health Effects
`
`Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Inflammation of the
`eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening,
`or, occasionally, blistering. Follow safe industrial hygiene practices and always wear proper protective equipment when
`handling this compound.
`
`Chronic Health Effects
`
`CARCINOGENIC EFFECTS : Classified by the IARC as a Group 2B carcinogen.
`(sufficient evidence in animals, no adequate data in humans)
`Tumorigenic: Mouse (implant) 400 mg/kg. Equivocal tumorigenic by RTECS criteria.
`MUTAGENIC EFFECTS : Not available.
`TERATOGENIC EFFECTS : Not available.
`DEVELOPMENTAL TOXICITY: Not available.
`Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions.
`
`Section IV.
`
`First Aid Measures
`
`Eye Contact
`
`Skin Contact
`
`Inhalation
`
`Ingestion
`
`Check for and remove any contact lenses. DO NOT use an eye ointment. Flush eyes with running water for a minimum
`of 15 minutes, occasionally lifting the upper and lower eyelids. Seek medical attention. Treat symptomatically and
`supportively.
`
`If the chemical gets spilled on a clothed portion of the body, remove the contaminated clothes as quickly as possible,
`protecting your own hands and body. Place the victim under a deluge shower. If the chemical touches the victim's
`exposed skin, such as the hands: Gently and thoroughly wash the contaminated skin with running water and non-abrasive
`soap. Be particularly careful to clean folds, crevices, creases and groin. Cover the irritated skin with an emollient. Seek
`medical attention. Treat symptomatically and supportively. Wash any contaminated clothing before reusing.
`
`If the victim is not breathing, perform artificial respiration. Loosen tight clothing such as a collar, tie, belt or waistband. If
`breathing is difficult, oxygen can be administered. Seek medical attention. Treat symptomatically and supportively.
`
`INDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat.
`Loosen tight clothing such as a collar, tie, belt, or waistband. If the victim is not breathing, administer artificial respiration.
`Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material
`was ingested; the absence of such signs, however, is not conclusive. Seek immediate medical attention and, if possible,
`show the chemical label. Treat symptomatically and supportively.
`
`Section V.
`
`Fire and Explosion Data
`
`Flammability
`
`Combustible.
`
`Auto-Ignition
`
`Not available.
`
`Flash Points
`
`196°C (384.8°F).
`
`Flammable Limits
`
`Not available.
`
`Combustion Products
`
`These products are toxic carbon oxides (CO, CO 2).
`
`Fire Hazards
`
`No specific information is available regarding the flammability of this compound in the presence of various materials.
`
`Explosion Hazards
`
`Risks of explosion of the product in presence of mechanical impact: Not available.
`Risks of explosion of the product in presence of static discharge: Not available.
`No additional information is available regarding the risks of explosion.
`Emergency phone number (800) 424-9300
`Continued on Next Page
`
`Printed 2/24/2005.
`
`Purdue 2012
`Collegium v. Purdue, PGR2018-00048
`
`

`

`S0163
`
`Fire Fighting Media
`and Instructions
`
`S01e namet)
`Spill Cleanup
`Instructions
`
`Stearic Acid
`
`Page 2
`
`SMALL FIRE: Use DRY chemicals, CO 2, water spray or foam.
`LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet.
`
`Accidental Release Measures
`
`Irritating material. Harmful material.
`In case of a spill and/or a leak, always shut off any sources of ignition, ventilate the area, and exercise caution. Use a
`shovel to put the material into a convenient waste disposal container. Finish cleaning the spill by rinsing any
`contaminated surfaces with copious amounts of water. Consult federal, state, and/or local authorities for assistance on
`disposal.
`
`Section VII.
`Handling and Storage
`Information
`
`Handling and Storage
`IRRITANT. POSSIBLE CARCINOGEN. Keep away from heat and sources of ignition. Mechanical exhaust required.
`When not in use, tightly seal the container and store in a dry, cool place. Avoid excessive heat and light. DO NOT
`ingest. DO NOT breathe dust. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek
`medical advice immediately and show the container or the label. Treat symptomatically and supportively. Avoid contact
`with skin and eyes.
`Always store away from incompatible compounds such as oxidizing agents, reducing agents, alkalis (bases).
`
`Section VIII.
`
`Exposure Controls/Personal Protection
`
`Engineering Controls
`
`Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
`recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
`airborne contaminants below the exposure limit.
`
`Personal Protection
`
`Splash goggles. Lab coat. Dust respirator. Boots. Gloves. A MSHA/NIOSH approved respirator must be used to avoid
`inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling
`this product.
`
`Exposure Limits
`
`This chemical is classified as a possible carcinogen. There is no acceptable exposure limit for a carcinogen.
`
`Section IX.
`
`Physical and Chemical Properties
`
`Physical state @ 20°C
`
`White flakes.
`
`Solubility
`
`Specific Gravity
`
`0.94 (water=1)
`
`Easily soluble in diethyl ether.
`Soluble in acetone, chloroform, carbon
`tetrachloride, toluene, carbon disulfide, hot
`alcohol.
`Slightly soluble in benzene.
`Insoluble in cold water, hot water.
`
`Molecular Weight
`
`284.48
`
`Partition Coefficient
`
`Not available.
`
`Boiling Point
`
`232°C (449.6°F) @ 15mmHg
`
`Vapor Pressure
`
`1 mm of Hg (@ 20°C)
`
`Melting Point
`
`67 to 69°C (152.6 to 156.2°F)
`
`Vapor Density
`
`9.8 (Air = 1)
`
`Refractive Index
`
`Not available.
`
`Volatility
`
`Not available.
`
`Critical Temperature
`
`Not available.
`
`Viscosity
`
`Not available.
`
`Odor
`
`Taste
`
`Not available.
`
`Not available.
`
`Section X.
`
`Stability and Reactivity Data
`
`Stability
`
`This material is stable if stored under proper conditions. (See Section VII for instructions)
`
`Conditions of Instability
`
`Avoid excessive heat and light.
`
`Incompatibilities
`
`Reactive with oxidizing agents, reducing agents, alkalis (bases).
`
`Section XI.
`
`Toxicological Information
`
`RTECS Number
`
`WI2800000
`
`Routes of Exposure
`
`Eye contact. Inhalation. Ingestion. Skin contact.
`
`Toxicity Data
`
`Rat LD50 (intravenous) 21500 ug/kg
`Mouse LD50 (intravenous) 23000 mg/kg
`
`Chronic Toxic Effects
`
`CARCINOGENIC EFFECTS : Classified by the IARC as a Group 2B carcinogen.
`(sufficient evidence in animals, no adequate data in humans)
`Tumorigenic: Mouse (implant) 400 mg/kg. Equivocal tumorigenic by RTECS criteria.
`MUTAGENIC EFFECTS : Not available.
`TERATOGENIC EFFECTS : Not available.
`DEVELOPMENTAL TOXICITY: Not available.
`Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions.
`
`Continued on Next Page
`
`Printed 2/24/2005.
`
`Emergency phone number (800) 424-9300
`
`Purdue 2012
`Collegium v. Purdue, PGR2018-00048
`
`

`

`S0163
`Acute Toxic Effects
`
`Stearic Acid
`Irritating to eyes and skin on contact. Inhalation causes irritation of the lungs and respiratory system. Inflammation of the
`eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening,
`or, occasionally, blistering. Follow safe industrial hygiene practices and always wear proper protective equipment when
`handling this compound.
`
`Page 3
`
`Section XII.
`
`Ecological Information
`
`Ecotoxicity
`
`Not available.
`
`Environmental Fate
`
`Not available.
`
`Section XIII.
`
`Disposal Considerations
`
`Waste Disposal
`
`Recycle to process, if possible. Consult your local or regional authorities. You may be able to dissolve or mix material with
`a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all
`federal, state, and local regulations when disposing of this substance.
`
`Section XIV.
`
`Transport Information
`
`DOT Classification
`
`Not a DOT controlled material (United States).
`
`PIN Number
`
`Not applicable.
`
`Proper Shipping Name
`
`Not applicable.
`
`Packing Group (PG)
`
`Not applicable.
`
`DOT Pictograms
`
`Other Regulatory Information and Pictograms
`Section XV.
`TSCA Chemical Inventory
`(EPA)
`
`This product is ON the EPA Toxic Substance Control Act (TSCA) inventory.
`
`WHMIS Classification
`(Canada)
`
`WHMIS CLASS D-2B: Material causing other toxic effects (TOXIC).
`
`EINECS Number (EEC)
`
`200-313-4
`
`EEC Risk Statements
`
`R36/38- Irritating to eyes and skin.
`
`Japanese Regulatory Data
`
`Not available.
`
`Section XVI.
`
`Other Information
`
`Version 1.0
`Validated on 6/30/1997.
`Printed 2/24/2005.
`
`Notice to Reader
`
`TCI laboratory chemicals are for research purposes only and are NOT intended for use as drugs, food additives, households, or pesticides. The information herein is believed to be correct, but does not
`claim to be all inclusive and should be used only as a guide. Neither the above named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness of the
`information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All chemical reagents must be handled with the recognition that their chemical,
`physiological, toxicological, and hazardous properties have not been fully investigated or determined. All chemical reagents should be handled only by individuals who are familiar with their potential
`hazards and who have been fully trained in proper safety, laboratory, and chemical handling procedures. Although certain hazards are described herein, we can not guarantee that these are the only hazards
`which exist. Our MSDS sheets are based only on data available at the time of shipping and are subject to change without notice as new information is obtained. Avoid long storage periods since the
`product is subject to degradation with age and may become more dangerous or hazardous. It is the responsibility of the user to request updated MSDS sheets for products that are stored for extended
`periods. Disposal of unused product must be undertaken by qualified personnel who are knowledgeable in all applicable regulations and follow all pertinent safety precautions including the use of
`appropriate protective equipment (e.g. protective goggles, protective clothing, breathing equipment, facial mask, fume hood). For proper handling and disposal, always comply with federal, state, and local
`regulations.
`
`Printed 2/24/2005.
`
`Purdue 2012
`Collegium v. Purdue, PGR2018-00048
`
`