CURRICULUM VITAE
`MANSOOR M. AMIJI, PhD, RPh
`
`
`
`CONTACT INFORMATION
`Campus Address:
`Northeastern University
`360 Huntington Avenue
`140 The Fenway Building, Room 156
`Boston, Massachusetts 02115
`
`Office #: (617) 373-3137
`Fax #: (617) 373-8886
`E-mail: m.amiji@northeastern.edu
`Personal Website: http://www.northeastern.edu/amijilab
`LinkedIn: https://www.linkedin.com/in/mansoor-amiji-46109629/
`ResearchGate: https://www.researchgate.net/profile/Mansoor-Amiji
`Google Scholar: https://scholar.google.com/citations?user=0BKYPYMAAAAJ&hl=en
`
`Residential Address:
`195 Richie Road
`Attleboro, Massachusetts 02703
`Residence #: (508) 222-3034
`Mobile #: (617) 839-9679
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`EDUCATION AND TRAINING
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`September, 1984 - June, 1988: Undergraduate Student in the College of Pharmacy and Allied Health Professions,
`Northeastern University, Boston, MA.
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`September, 1986 - May, 1988: Undergraduate Honors Student Research Project Entitled “Preparation and
`Characterization of Doxorubicin-Dextran Conjugates” – Major Advisor: Professor Mehdi Boroujerdi.
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`June, 1988: Bachelor of Science Degree in Pharmacy (magna cum laude).
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`July, 1988: Registered Pharmacist – Licensed to practice in Massachusetts (license # 20415)
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`August, 1988 - July, 1992: Doctoral Student in the Department of Industrial and Physical Pharmacy, College of
`Pharmacy, Purdue University, West Lafayette, Indiana.
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`August, 1988 - June, 1989: Teaching Assistant in the Department of Industrial and Physical Pharmacy.
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`July, 1989 - June, 1992: Research Assistant in the Department of Industrial and Physical Pharmacy.
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`July, 1989 - June, 1992: Doctoral Dissertation Research Entitled “Surface Modification of Biomaterials with Water-
`Soluble Polymers: A Steric Repulsion Approach” - Major Advisor: Professor Kinam Park.
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`July, 1992: Doctor of Philosophy Degree in Pharmaceutics and Pharmaceutical Sciences.
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`PROFESSIONAL AND ACADEMIC POSITIONS
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`August, 1992 – December, 1992: Senior Research Scientist, Columbia Research Laboratories, Madison, WI.
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`January, 1993 – June, 1999: Assistant Professor, Department of Pharmaceutical Sciences, School of Pharmacy,
`Northeastern University, Bouve College of Health Sciences, Boston, MA.
`
`SAB1020
`U.S. Pat. No. 10,945,970
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`July, 1999 – April, 2006: Associate Professor (with tenure), Department of Pharmaceutical Sciences, School of
`Pharmacy, Bouve College of Health Sciences, Northeastern University, Boston, MA.
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`June, 2000 – December, 2000: Visiting Research Scholar. Department of Chemical Engineering, Massachusetts
`Institute of Technology, Cambridge, MA. (Sabbatical leave appointment in Institute Professor Robert Langer’s
`group).
`
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`May, 2006 – Present: Full Professor (primary), Department of Pharmaceutical Sciences, School of Pharmacy, Bouve
`College of Health Sciences, Northeastern University, Boston, MA.
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`February, 2010 – April, 2016: Bouve College Distinguished Professor, Department of Pharmaceutical Sciences, School
`of Pharmacy, Bouve College of Health Sciences, Northeastern University, Boston, MA.
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`September, 2012 – July, 2018: Affiliate Faculty Member, Department of Chemical Engineering, College of Engineering,
`Northeastern University, Boston, MA.
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`September, 2013 – Present: Affiliate Faculty Member, Department of Biomedical Engineering, College of Engineering,
`Northeastern University, Boston, MA.
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`January, 2014 – September, 2017: Distinguished Adjunct Professor, Faculty of Pharmacy, King Abdulaziz University,
`Jeddah, Saudi Arabia.
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`April, 2016 – Present: University Distinguished Professor, Department of Pharmaceutical Sciences, School of
`Pharmacy, Bouve College of Health Sciences, Northeastern University, Boston, MA.
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`March, 2017 – August, 2018: Distinguished Adjunct Professor, Institute for Research and Medical Consultation (IRMC),
`Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia.
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`August 2018 – Present: Professor (secondary). Department of Chemical Engineering, College of Engineering,
`Northeastern University, Boston, MA.
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`ADMINISTRATIVE AND LEADERSHIP POSITIONS
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`July, 1995 – June 2000: Pharmaceutics Group Leader, Department of Pharmaceutical Sciences, School of Pharmacy,
`Bouve College of Health Sciences, Northeastern University, Boston, MA.
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`September, 2002 – June, 2004: Education and Outreach Coordinator, Molecular Biotechnology Initiative at Northeastern
`University, Boston, MA.
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`July, 2002 – Present: Director, Laboratory of Biomaterials and Advanced Nano-Delivery Systems (BANDS) at
`Northeastern University, Boston, MA
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`July, 2003 – December, 2016: Co-Director, Nanomedicine Education and Research Consortium (NERC) at
`Northeastern University, Boston, MA.
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`July, 2005 – December, 2008: Associate Chairman, Department of Pharmaceutical Sciences, School of Pharmacy,
`Bouve College of Health Sciences, Northeastern University, Boston, MA.
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`January, 2009 – January, 2010: Interim Chairman, Department of Pharmaceutical Sciences, School of Pharmacy.
`Bouve College of Health Sciences, Northeastern University, Boston, MA.
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`February, 2010 – April, 2016: Chairman, Department of Pharmaceutical Sciences, School of Pharmacy, Bouve College
`of Health Sciences, Northeastern University, Boston, MA.
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`RESEARCH INTERESTS
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`The primary focus of research in my laboratory is on the development of biocompatible materials from natural and synthetic
`polymers, target-specific drug and gene delivery systems for cancer and infectious diseases, and nanotechnology
`applications for medical diagnosis, imaging, and therapy. Specific projects that we are currently pursuing include:
`
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` Preparation and characterization of polymeric membranes and microcapsules with controlled permeability
`properties for medical and pharmaceutical applications.
` Role of hypoxia and mitochondrial dysfunction in the tumor microenvironment in development of therapeutic
`resistance, angiogenesis, and metastasis.
`Intracellular and sub-cellular delivery systems for drugs and genes using target-specific, long-circulating,
`biodegradable polymeric nanoparticles.
` Localized delivery of cytotoxic and anti-angiogenic drugs, siRNA, and genes for solid tumors in novel biodegradable
`polymeric nanoparticles.
` Local administration of drugs and nucleic acid-containing nanovectors immobilized on stents for the treatment of
`arterial diseases (e.g., coronary restenosis).
` Target-specific drug, gene, and vaccine delivery systems for diseases of the gastro-intestinal tract.
` Systemic and local delivery of DNA, mRNA, siRNA, microRNA, and CRISPR-Cas9 constructs for genetic
`engineering and therapeutic applications.
` Novel oil-in-water nanoemulsion formulations for drug delivery through the gastrointestinal tract and across the
`blood-brain barrier.
` Systemic and mucosal vaccination using novel immune-modulatory strategies and delivery systems.
`Intranasal and trans-nasal administration of biodegradable formulations, including sustained release implants, to
`
`enhance brain delivery of small molecules, peptides, proteins, siRNA, mRNA, and genes for treatment of chronic
`neurodegenerative diseases and brain tumors.
` Functionalized inorganic nanoparticles - including gold, silver, iron oxide, metal alloys, and core-shell nanostructures
`- for biosensing, imaging, and targeted therapeutic applications.
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`
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`PUBLICATIONS [Google Scholar Hirsch “h” index = 95] – Clarivate Analytics/Web of Science
`Highly Cited Researcher (Top 1%) in Pharmacology & Toxicology in 2014 & 2018
`Book Editorship
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`Amiji, M.M. and Sandmann, B.J. (eds.). Applied Physical Pharmacy. Published by McGraw-Hill Medical
`Publishing Division. New York, NY. 2002.
`
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`Amiji, M.M. (ed.) Polymeric Gene Delivery: Principles and Applications. Published by CRC Press, LLC (a
`subsidiary of Taylor and Francis). Boca Raton, FL. 2004.
`
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`Amiji, M.M. (ed.). Nanotechnology for Cancer Therapy. Published by CRC Press, LLC (a subsidiary of Taylor
`and Francis). Boca Raton, FL. 2007.
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`Torchilin, V.P. and Amiji, M.M. (eds.). Handbook of Materials for Nanomedicine. Publication of the Biomedical
`Nanotechnology Series, (10 Volumes Book Series edited by Torchilin, V.P. and Amiji, M.M.). Volume 1,
`Pan Published by Stanford Publishing, Singapore, 2010.
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` Amiji, M.M., Cook, T., and Mobley, W.C. (eds.). Applied Physical Pharmacy – Second Edition. Published by
`McGraw-Hill Medical Publishing Division. New York, NY, 2014.
`
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` Merkel, O.M. and Amiji, M.M. (eds). Advances and Challenges in the Delivery of Nucleic Acid Therapeutics
`– Volumes 1. E-Books Published by Future Science, LTD, London, UK. 2015.
`https://www.futuremedicine.com/doi/book/10.4155/9781910419922.
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` Merkel, O.M. and Amiji, M.M. (eds). Advances and Challenges in the Delivery of Nucleic Acid Therapeutics
`– Volumes 2. E-Books Published by Future Science, LTD, London, UK. 2015.
`https://www.futuremedicine.com/doi/book/10.4155/9781910419953.
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` Milane, L.S. and Amiji, M.M. (eds). Nanomedicine for Inflammatory Diseases. Published by CRC Press, LLC
`(a subsidiary of Taylor and Francis). Boca Raton, FL. 2017.
`
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`Singh, A and Amiji, M.M. (eds). Stimuli-Responsive Drug Delivery Systems. Royal Society of Chemistry
`Biomaterial Series Publication. Royal Society of Chemistry, London, UK. 2018
`
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` Amiji, M.M. and Ramesh, R. (eds). Diagnostic and Therapeutic Applications of Exosomes in Cancer. Elsevier
`Publishing Company. San Diego, CA. 2018.
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`Mobley, W.C., Amiji, M.M., and Cook, T., (eds.). Applied Physical Pharmacy – Third Edition. Published by
`McGraw-Hill Medical Publishing Division. New York, NY, 2019.
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`Amiji, M.M. and Milane, L.S. (eds). Cancer Immunology and Immunotherapy. Volume 1 in Delivery Strategies
`and Engineering Technologies in Cancer Immunotherapy Series. Academic Press/Elsevier Publishing
`Company. Oxford, The United Kingdom, 2021.
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`Amiji, M.M. and Milane, L.S. (eds). Systemic Drug Delivery Strategies. Volume 2 in Delivery Strategies and
`Engineering Technologies in Cancer Immunotherapy Series. Academic Press/Elsevier Publishing
`Company. Oxford, The United Kingdom, 2021.
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`Amiji, M.M. and Milane, L.S. (eds). Engineering Technologies and Clinical Transition. Volume 3 in Delivery
`Strategies and Engineering Technologies in Cancer Immunotherapy Series. Academic Press/Elsevier
`Publishing Company. Oxford, The United Kingdom, 2021.
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`Milane, L.S. and Amiji, M.M. (eds). Organelle and Molecular Targeting. CRS Press/Taylor & Francis, Boca
`Raton, FL (In press).
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`Book Chapters
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`Amiji, M. and Park, K. Surface modification of polymeric biomaterials with poly(ethylene oxide): a steric repulsion approach.
`In Shalaby, S.W., Ikada, Y., Langer, R., and Williams, J. (eds.) Polymers of Biological and Biomedical Significance.
`American Chemical Society Symposium Series Publication, Volume 540. Published by the American Chemical Society,
`Washington, DC. 1994, pp 135-146.
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` Amiji, M. and Park, K. Surface modification of polymeric biomaterials with poly(ethylene oxide), albumin, and heparin for
`reduced thrombogenicity. In Cooper, S.L., Bamford, C.H., and Tsuruta, T. (eds.) Polymer Biomaterials: In Solution, as
`Interfaces, and as Solids. Published by VSP, The Netherlands. 1995, pp 535-552.
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`Amiji, M., Kamath, K., and Park, K. Albumin-modified biomaterial surfaces for reduced thrombogenicity. In Wise, D.L.,
`Altobelli, D.E., Grasser, J.D., Shwartz, E.R., Trantolo, D.J., and Yaszemski, M. (eds.) Encyclopedic Handbook of
`Biomaterials and Bioengineering - Part B Applications. Volume II. Published by Marcel Dekker, Inc., New York, NY.
`1995, pp 1057-1070.
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`Amiji, M.M. Surface modification of chitosan to improve blood compatibility. In Pandalai, S.G. (eds.). Recent Research
`Developments in Polymer Science, Volume III. Published by Transworld Research Network, Trivandrum, India. 1999,
`pp 31-39.
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`Hejazi, R. and Amiji, M. Chitosan-based delivery systems: physicochemical properties and pharmaceutical applications. In
`Dumitriu, S. (eds.). Polymeric Biomaterials. Second Edition, Revised and Expanded. Published by Marcel Dekker, Inc.,
`New York, NY. 2001, Chapter 10, pp 213-238.
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`Kaul, G. and Amiji, M. Polymeric gene delivery systems. In. Wise, D.L., Hasirci, V., Lewandrowski, K.-U., Yaszemski, M.J.,
`Altobelli, D.W., and Trantolo, D.J. (eds.). Tissue Engineering and Novel Delivery Systems. Published by Marcel Dekker,
`Inc., New York, NY. 2004, Chapter 16, pp 333-367.
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`Kommareddy, S. and Amiji, M. Targeted drug delivery to tumor cells using colloidal carriers. In Lu, D.R. and Oie, S. (eds.).
`Cellular Drug Delivery: Principles and Practice. Published by Humana Press, Inc., Totowa, NJ. 2004, Chapter 10, pp
`181-215.
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`Kaul, G. and Amiji, M.M. Protein nanospheres for gene delivery. In Amiji, M.M. (ed.) Polymeric Gene Delivery: Principles
`and Applications. Published by CRC Press, LLC. Boca Raton, FL. 2004, Chapter 27, pp. 429-447.
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`Kommareddy, S., Shenoy, D.B., and Amiji, M.M. Gelatin nanoparticles and their biofunctionalization. In Kumar, C. (ed.).
`Nanotechnologies for the Life Sciences, Volume 2: Biological and Pharmaceutical Nanomaterials. Published by Wiley-
`VCH, Berlin, Germany. 2005, Chapter 11, pp. 330-353.
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`Bhavsar, M.D., Shenoy, D.B., and Amiji, M.M. Nanoparticles for delivery in the gastrointestinal tract. In Torchilin, V.P. (ed.).
`Nanoparticulates as Drug Carriers. Published by Imperial College Press, London, United Kingdom, 2006, Chapter 26,
`pp 609-648.
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`Shenoy, D.B. and Amiji, M.M. An overview of condensing and non-condensing polymeric systems for gene delivery. In
`Friedmann, T. and Rossi, J (eds.). Gene Transfer: Delivery and Expression of DNA and RNA – A Laboratory Manual.
`Published by Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 2007, Chapter 34, pp 395-403.
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`Kommareddy, S. and Amiji, M.M. Protein nanospheres for gene delivery: preparation and in vitro transfection studies with
`gelatin nanoparticles. In Friedmann, T. and Rossi, J. (ed.). Gene Transfer: Delivery and Expression of DNA and RNA
`– A Laboratory Manual. Published by Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 2007, Chapter
`52, pp 527-540.
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`Kommareddy, S., Shenoy, D.B., and Amiji, M.M. Long-circulating polymeric nanocarriers for drug and gene delivery in
`cancer. In Amiji, M.M. (ed.). Nanotechnology for Cancer Therapy. Published by CRC Press, Boca Raton, FL. 2007,
`Chapter 13, pp 231-242.
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`Tiwari, S.B. and Amiji, M.M. Nanoemulsions for tumor targeted drug delivery. In Amiji, M.M. (ed.). Nanotechnology for
`Cancer Therapy. Published by CRC Press, Boca Raton, FL. 2007, Chapter 35, pp 723-739.
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`Iftemia, N., Amiji, M.M., and Iftemia, I. Nanotechnology applications in cancer diagnosis and therapy. In Yih, T.C. and
`Talpasanu, I. (ed.). Micro and Nano Manipulations for Biomedical Applications. Published by Springer Publishing, New
`York, NY, 2008, Chapter 2, pp 13-41.
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`Magadala, P., van Vlerken, L.E. Shahiwala, A., and Amiji, M.M. Multifunctional polymeric nanosystems for tumor-targeted
`delivery. In Torchilin, V.P. (ed.). Multifunctional Pharmaceutical Nanocarriers. Published by Springer Publishing, New
`York, NY 2008, Chapter 2, pp 33-64.
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`Nagesha, D., Devalapally H.K., Sridhar, S., and Amiji, M. Multifunctional magnetic nanosystems for tumor imaging, targeted
`delivery, and thermal therapy. In Torchilin, V.P. (ed.). Multifunctional Pharmaceutical Nanocarriers. Published by
`Springer Publishing, New York, NY 2008, Chapter 14, pp 381-408.
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`Bhavsar, M.B., Jain, S., and Amiji, M.M. Nanotechnology in oral drug delivery. In Xu, J. J. and Ekins, S. (eds.). Drug Efficacy,
`Safety, and Biologics Discovery: Emerging Technologies and Tools. Published by Wiley Publishing, New York, NY
`2009, Chapter 10, pp. 231-275.
`
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`Brito, L., Chadwick, S., and Amiji, M.M. Gelatin-based gene delivery systems. In Morishita, M. and Park, K. (eds.). Biodrug
`Delivery Systems: Fundamentals, Applications, and Clinical Developments”. Published by Informa Healthcare Group,
`New York, NY 2009, Chapter 20, pp 323-341.
`
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`Ganta, S., Iyer, A.K., and Amiji, M.M. Multifunctional stimuli-responsive nanoparticles for delivery of small and
`macromolecular therapeutics. In Mahato, R.I. and Narang, A.S. (eds.). Targeted Delivery of Small and Macromolecular
`Drugs. Published by CRC Press, Inc., Boca Raton, FL, 2010 Chapter 20, pp 555-586.
`
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`Iyer, A.K., Ganta, S., and Amiji, M.M. Polymeric nanoparticles as target-specific delivery systems. In Torchilin, V.P. and
`Amiji, M.M. (eds.). Handbook of Materials for Nanomedicine: Volume 1. Published by Pan Stanford Publishing,
`Singapore, 2010, Chapter 2, pp 81-130.
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`Matthäus, C., Chernenko, T., Miljković, M., Quintero, L., Miljkovic, M., Milane, L., Kale, A., Amiji, M., Torchilin, V., and Diem,
`M. Raman microspectral imaging of cells and intracellular drug delivery using nanocarrier systems. In Dieing, T., and
`Hollricher, O., and Toporski, J. (eds.). Confocal Raman Microscopy, Springer Series in Optical Science, Volume 158.
`Published by Springer Verlag, Heidelberg, Germany. 2010, pp. 137-163.
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`Iftimia, N., Amiji, M., Milane, L., and Oldenburg, A. Nanotechnology approaches for contrast enhancement in optical imaging
`and disease targeted therapy. In Iftimia, N., Brugge, W., and Hammer, D.X (eds.). Advances in Optical Imaging for
`Clinical Medicine, Chapter 16. Published by Wiley Publishing, New York, NY. 2011. Chapter 16, pp 455-504.
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`Shahiwala, A., Vyas, T.K., and Amiji, M.M. Nanotechnology for targeted delivery of drugs and genes. In Nalwa, H.S. (Ed.).
`Encyclopedia of Nanoscience and Nanotechnology, 2nd Edition, Published by American Scientific Publishers, New
`York, NY. 2011. Volume 19, pp 265-295.
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`Kalariya, M., Ganta, S., Attarwala, H., and Amiji, M. Multifunctional lipid nano-systems for cancer prevention and therapy.
`In Souto, E. (ed.). Advanced Anticancer Approaches with Multifunctional Lipid Nanocarriers. Published by iSmithers
`Rapra Publishing, Inc., Billingham, UK. 2011. Chapter 3, pp 29-54.
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`Amiji, M.M. Hornicek, F., and Duan, Z.-F. Gene silencing with nanoparticle-encapsulated siRNA to overcome tumor
`multidrug resistance. In Srirajaskanthan, R. and Preedy, V.R. (eds.). Published by Nanomedicine and Cancer. Science
`Publishers-CRC Press, Enfield, NH. 2012. Chapter 15, pp 290-306.
`
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`Jain, S. and Amiji, M. Macrophage-targeted nanoparticle delivery systems. In Pru’dhomme, R.K. and Svenson, S. (eds.).
`Multifunctional Nanoparticles for Drug Delivery Applications: Imaging, Targeting, and Delivery. Published by Springer
`Publishing, New York, NY. 2012 Chapter 4, pp 47-84.
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`Jain, S. and Amiji, M. Target-specific chitosan-based nanoparticle systems for nucleic acid delivery. In Sarmento, B. and
`das Neves, J. (eds.) Chitosan-Based Systems for Biopharmaceuticals: Delivery, Targeting, and Polymer Therapeutics.
`Published by John Wiley & Sons Publishing, Chichester, West Sussex, UK. 2012 Chapter 15, pp 277-300.
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`Singh, A., Chernenko, T., and Amiji. M. Theranostic applications of plasmonic nanosystems. In Hepel, M. and Zhong, C.J.
`(eds.). Functional Nanoparticles for Bioanalysis, Nanomedicine and Bioelectronic Devices. Volume 2. Published by
`American Chemical Society Publications, Washington, DC. 2012 Chapter 15, pp 383-413.
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`Iyer, A., Ganesh, S., Zhou, Q.L., and Amiji, M. Multifunctional polymeric nano-systems for RNA interference therapy. In
`Wang., W. and Singh, M. (eds.) Biological Drug Products: Development and Strategies. Published by John Wiley
`Publishers, Nutley, NJ. 2013 Chapter 18, pp 569-600.
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`Singh, A., Iyer, A., Ganta, S., and Amiji, M. Multifunctional nanosystems for cancer therapy. In Park, K. (ed.). Biomaterials
`for Cancer Therapeutics: Diagnosis, Prevention and Therapy. Published by Woodhead Publishing, Inc., Cambridge,
`UK. 2013 Chapter 14, pp 387-414.
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`Chernenko, T., Milane, L., Matthäus, C., Diem, M., and Amiji, M. Raman microspectral imaging for label-free detection of
`nanoparticle-mediated cellular and sub-cellular drug delivery. In Li, C. and Tian, M. (eds.). Drug Delivery Applications
`of Non-Invasive Imaging: Validation from Biodistribution to Sites of Action. Published by John Wiley & Sons Publishing,
`Hoboken, NJ. 2013 Chapter 4, pp 70-90.
`
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`Jain, S., and Amiji, M. Nanoparticles-in-microsphere oral systems (NiMOS) for nucleic acid therapy in the gastrointestinal
`tract. In Sarmento, B. and das Neves, J. (eds.) Mucosal Delivery of Biopharmaceuticals: Biology, Challenges and
`Strategies. Published by Springer Science Publishing, New York, NY. 2014 Chapter 11, pp 283-312.
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`Deshpande, D., Jamal-Allial, A., Sankhe, K., and Amiji, M. Nanotechnology applications in local arterial drug delivery. In
`Domb, A. and Khan, W. (eds). Advances in Delivery Science and Technology - Focal Controlled Drug Therapy.
`Published by the Controlled Release Society - Springer Science Publishing, New York, NY. 2014 Chapter 17, pp 359-
`385.
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`Ganesh, S., Iyer, A.K., and Amiji, M.M. Combinatorial-designed hyaluronic acid nanoparticles for tumor targeted drug and
`small interfering RNA delivery. In Collins, M. (ed.). Hyaluronic Acid for Biomedical and Pharmaceutical Applications.
`Published by Simthers Rapra, Shrewsbury, The United Kingdom. 2014 Chapter 3, pp 57-88.
`
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`Iyer, A.K., Ganesh, S., and Amiji, M.M. Nano-platforms for tumor-targeted delivery of nucleic acid therapies. In Alonso, M.J.
`and Fuentes, M.G. (eds). Nano-Oncologicals: New Targeting and Delivery Approaches. Published by the Controlled
`Release Society - Springer Publishing, New York, NY. 2014 Chapter 10, pp 269-291.
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`Singh, A., Oka, A.J., Pandya, P., and Amiji, M.M. Multimodal nano-systems for cancer diagnosis, imaging, and therapy. In
`Alonso, M.J. and Fuentes, M.G. (eds). Nano-Oncologicals: New Targeting and Delivery Approaches. Published by the
`Controlled Release Society - Springer Publishing, New York, NY. 2014 Chapter 13, pp 351-388.
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`Singh, A., Iyer, A., and Amiji, M. Polymeric nano-systems for integrated image-guided cancer therapy. In V.P. Torchilin
`(ed.). Handbook of Nano-Biomedical Research: Fundamentals, Applications, and Recent Developments. Volume 1:
`Materials for Nanomedicine. Published by World Scientific Publishing, Singapore. 2014 Chapter 6, pp 199-233.
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`Ganta, S., Singh, A., Coleman, T.P., Williams, D., and Amiji, M. Pharmaceutical nanotechnology: overcoming drug delivery
`challenges in contemporary medicine. In Ge, Y., Li, S., Wang, S., and Moore, R. (eds.). Nanomedicine: Principles and
`Perspectives - Volumes 1 & 2. Published by Springer Publishing, New York, NY. 2014 Chapter 10, pp 191-236.
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`Shah, R., Brito, L., Singh, M., O’Hagan, D., and, Amiji, M. Emulsions as vaccine adjuvants. In Foged, C., Rades, T., Perrie,
`Y., and Hook, S. (eds). Subunit Vaccine Delivery. Published by the Controlled Release Society - Springer Publishing,
`New York, NY 2014 Chapter 4, pp 59-76.
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`Shah, L., Iyer, A., Talekar, M., and Amiji, M. Image-guided delivery of therapeutics to the brain. In Devarajan, P. and Jain,
`S. (eds). Targeted Drug Delivery – Concepts and Design. Published by the Controlled Release Society - Springer
`Publishing, New York, NY 2015, Chapter 4, pp 151-178.
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`Attarwala, H. and Amiji, M. Multi-compartmental oral delivery systems for oligonucleotide therapeutics. In Merkel, O.M. and
`Amiji, M.M. (eds). Advances and Challenges in the Delivery of Nucleic Acid Therapeutics – Volume 2. E-Book
`Published by Future Science, LTD, London, UK. 2015, Chapter 14, pp 71-86.
`
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`Attarwala, H. and Amiji, M. Biodegradable polyester-based multi-compartmental delivery systems for oral nucleic acid
`therapy. In Majeti, R. (ed.). Handbook of Polyester Drug Delivery Systems. Pan Stanford Publishing, Singapore. 2016,
`Chapter 13, pp 417-443.
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`Singh, A., Tran, T.H., and Amiji, M. Redox-responsive nano-delivery systems for cancer therapy. In V. Weissig and A.
`Prokop (eds.). Fundamentals of Biomedical Technologies Series. Intracellular Delivery, Volume 3 – Market Entry
`Barriers of Nanomedicines. Published by Springer Publishing, New York, NY. 2016, Chapter 10, pp 255-272.
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`Parayath, N., Pawar, G., Avachat, C., Miyake, M.M., Bleier, B.S., and Amiji, M.M. The biology and clinical treatment of
`neurodegenerative diseases. In Milane, L.S. and Amiji, M.M. (eds). Nanomedicine for Inflammatory Diseases.
`Published by CRC Press, LLC (a subsidiary of Taylor and Francis). Boca Raton, FL. 2017, Chapter 8, pp 289-318.
`
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`Singh, A. and Amiji, M.M. Combinatorial approach in rationale design of polymeric nanomedicines for cancer. In Sarmento,
`B. and Das Neves, J. (eds). Biomedical Applications of Functionalized Nanomaterials. Published by Elsevier Press,
`Amsterdam, The Netherlands. 2018, Chapter 13, pp 371-398.
`
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`Su, M.J., Parayath, N., and Amiji, M.M. Exosome-mediated communication in the tumor microenvironment. In Amiji, M.M.
`and Ramesh, R. (eds). Diagnostic and Therapeutic Applications of Exosomes in Cancer. Published by Elsevier
`Publishing Company. San Diego, CA. 2018, Chapter 11, pp 187-218.
`
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`Singh, A. and Amiji, M.M. Regulatory and commercialization challenges with smart materials. In Singh, A. and Amiji, M.M.
`(eds). Stimuli-Responsive Drug Delivery Systems. Royal Society of Chemistry Biomaterial Series Publication. Royal
`Society of Chemistry, London, UK 2018, Chapter 14, pp 335-354.
`
`
`Singh A. and Amiji, M.M. The future of nano-biomaterials for drug delivery in cancer. In Park, K. (ed). Biomaterials for
`Cancer Therapy: Evolution and Innovation, 2nd Edition. Elsevier Press, LTD, Kidlington, UK, 2020, Chapter 21, pp 569-
`598.
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`Parayath, N.N. and Amiji, M.M. Preparation of hyaluronic acid-based nanoparticles for macrophage-targeted microRNA
`delivery and transfection. In Soloviev, M (ed.) Nanoparticles in Biology and Medicine: Methods and Protocols, Second
`Edition. Springer Publishing Company, Totowa, NJ. 2020, Chapter 7, pp 98-110.
`
`
`Singh, A., Rawal, M., and Amiji, M.M. Combinatorial approach to polymer design for nanomedicines. In Torchilin, V.P. (ed)
`Handbook of Materials for Nanomedicine – Polymeric Nanomaterials. Pan Stanford Publishing, Singapore. 2020,
`Chapter 1, pp 8-22.
`
`
`Ahmad, G. and Amiji, M.M.. Cellular therapeutics in immuno-oncology. In Amiji, M.M. and Milane, L. (eds). Cancer
`Immunology and Immunotherapy. Volume 1. Delivery Strategies and Engineering Technologies in Cancer
`Immunotherapy. Academic Press/Elsevier Publishing Company. Oxford, The United Kingdom. CA. 2021, Chapter 8,
`pp 197-236.
`
`
`Padmakumar, S., Huang, D., Parayath, N., Milane, L., and Amiji, M.M. Local and systemic delivery strategies for glioma
`immunotherapy. In Amiji, M.M. and Milane, L (eds). Systemic Drug Delivery Strategies. Volume 2. Delivery Strategies
`and Engineering Technologies in Cancer Immunotherapy. Academic Press/Elsevier Publishing Company. Oxford, The
`United Kingdom. 2021, Chapter 12, pp 295-332.
`
`
`Lodaya, R.N., Gregory, S., Amiji, M.M. and O’Hagan, D.T. Overview of vaccine adjuvants. In Kolhe, P and Ohtake, S. (eds).
`Practical Aspects of Vaccine Development – First Edition, Elsevier Publishing Company, Inc., San Diego, CA, 2021,
`Chapter 3, pp 9-26.
`
`
`Oza, D. and Amiji, M. Delivery of oligonucleotide therapeutics for macrophage reprogramming in inflammatory diseases. In
`Gupta, S and Pathak, Y (eds). Macrophage Targeted Delivery Systems: Basic Concepts and Therapeutic Application.
`Springer Nature Publishing Company, New York, NY (In press).
`
`
`Peer-Reviewed Articles
`
`Amiji, M., Park, H., and Park, K. Study on the prevention of surface-induced platelet activation by albumin coating. Journal
`of Biomaterials Science, Polymer Edition, 3: 375-388 (1992).
`
`
`Amiji, M. and Park, K. Prevention of protein adsorption and platelet adhesion on surfaces by PEO/PPO/PEO triblock
`copolymers. Biomaterials, 13: 682-692 (1992).
`
`
`Amiji, M. and Park, K. Surface modification by radiation-induced grafting of PEO/PPO/PEO triblock copolymers. Journal of
`Colloid and Interface Science, 155: 251-255 (1993).
`
`
`Amiji, M. and Park, K. Surface modification of polymeric biomaterials with poly(ethylene oxide), albumin, and heparin for
`reduced thrombogenicity. Journal of Biomaterials Science, Polymer Edition, 4: 217-234 (1993).
`
`
`Knuth, K., Amiji, M., and Robinson, J.R. Hydrogel delivery system for vaginal and oral applications: formulation and
`biological considerations. Advances in Drug Delivery Reviews, 11: 137-167 (1993).
`
`
`Amiji, M. and K. Park. Analysis on the surface adsorption of PEO/PPO/PEO triblock copolymers by radiolabeling and
`fluorescence techniques. Journal of Applied Polymer Science, 52: 539-544 (1994).
`
`
`Amiji, M.M. Permeability and blood compatibility properties of chitosan-poly(ethylene oxide) blend membranes for
`hemodialysis. Biomaterials, 16: 593-599 (1995).
`
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`Amiji, M.M. Pyrene fluorescence study of chitosan self-association in aqueous solution. Carbohydrate Polymers 26: 211-
`213 (1995).
`
`
`Amiji, M., Shah, E., and Boroujerdi, M. Photophysical characterization of insulin denaturation and aggregation at
`hydrophobic interfaces. Drug Development and Industrial Pharmacy, 21: 1661-1669 (1995).
`
`
`Patel, V.R. and Amiji, M.M. pH-sensitive swelling and drug release properties of chitosan-poly(ethylene oxide) semi-
`interpenetrating polymer network. In R. Ottenbrite, S. Huang, and K. Park (eds.) Hydrogels and Biodegradable
`Polymers for Bioapplications. American Chemical Society Symposium Series Publication. Volume 627. American
`Chemical Society, Washington, DC. 1996, pp 209-220.
`
`
`Patel, V.R. and Amiji, M.M. Preparation and characterization of freeze-dried chitosan-poly(ethylene oxide) hydrogels for
`site-specific antibiotic delivery in the stomach. Pharmaceutical Research 13: 588-593 (1996).
`
`
`Amiji, M.M. Surface modification of chitosan membranes by complexation-interpenetration of anionic polysaccharides for
`improved blood compatibility in hemodialysis. Journal of Biomaterials Science, Polymer Edition, 8: 281-298 (1996).
`
`
`Amiji, M., Tailor, R., Ly, M., and Goreham, J. Gelatin-poly(ethylene oxide) semi-interpenetrating polymer network with pH-
`sensitive swelling and enzyme-degradable properties for oral drug delivery. Drug Development and Industrial
`Pharmacy, 23: 575-582 (1997).
`
`
`Amiji, M.M. Synthesis of anionic poly(ethylene glycol) derivative for chitosan surface modification in blood-contacting
`applications. Carbohydrate Polymers, 32: 193-199 (1997).
`
`
`Amiji, M.M. Platelet adhesion and activation on an amphoteric chitosan derivative bearing sulfonate groups. Colloids and
`Surfaces. Part B: Biointerfaces, 10: 263-271 (1998).
`
`
`Qaqish, R.B. and Amiji, M.M. Synthesis of fluorescent chitosan derivative and its application for the study of chitosan-mucin
`interactions. Carbohydrate Polymers, 38: 99-107 (1999).
`
`
`Shah, S., Qaqish, R., Patel, V., and Amiji. M. Evaluation of the factors influencing stomach-specific delivery of antibacterial
`agents for Helicobacter pylori infection. Journal of Pharmacy and Pharmacology, 51: 667-672 (1999).
`
`
`Anderson, D., Nguyen, T., and Amiji, M. Chitosan-Pluronic® physical interpenetrating network: membrane fabrication and
`protein permeability studies. In M. El-Nokaly and H. Soini (eds.). Polysaccharides in Pharmaceutical and Cosmetic
`Applications. American Chemical Society Symposium Series Publication, Volume 737. American Chemical Society,
`Washington, DC 1999, pp 178-186.
`
`
`McQueen, C., Silvia, A., Lai, P.K., and Amiji, M. Surface and blood interaction properties of poly(ethylene oxide)-modified
`chitosan microspheres. S.T.P Pharma Sciences, 10: 95-100 (2000). [Year 2000 thematic issue on “Chitosan in Drug
`Delivery Systems”].
`
`
`Anderson, D., Nguyen, T., Lai, P.K., and Amiji, M. Evaluation of the permeability and blood-compatibility properties of
`membranes formed by physical interpenetration of chitosan with PEO/PPO/PEO triblock copolymers. Journal of
`Applied Polymer Science, 80: 1274-1284 (2001).
`
`
`Anderson, D. and Amiji, M. Preparation and evaluation of sustained drug release from Pluronic® polyol rectal suppositories.
`International Journal of Pharmaceutical Compounding, 5: 234-237 (2001).
`
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`Lynn, D.M., Amiji, M.M., and Langer, R. pH-responsive biodegradable polymer microspheres: rapid release of encapsulated
`material within the range of intracellular pH. Angewandte Chemie, International Edition, 40(9): 1707-1710 (2001).
`
`
`Amiji, M.M., Lai, P.-K., Shenoy, D.B., and Rao, M. Intratumoral administration of paclitaxel in an in situ gelling poloxamer
`407 formulation. Pharmaceutical Developm