(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT)
`
`9
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`WI PO I PCT
`
`International Bureau
`(43) International Publication Date
`16 May 2019 (16.05.2019)
`
`(51) International Patent Classification:
`A61B 5/00 (2006.01)
`
`(21) International Application Number:
`
`PCT/IB2018/0015 l 7
`
`(22) International Filing Date:
`12 November 2018 (12.11.2018)
`
`(25) Filing Language:
`
`(26) Publication Language:
`
`English
`
`English
`
`(30) Priority Data:
`62/584,404
`
`IO November 2017 (IO. l l.2017) US
`
`(71) Applicant: GALDERMA RESEARCH & DEVELOP(cid:173)
`MENT [FR/FR]; 2400 Route des Colles Les Templiers,
`06410 Biot (FR).
`
`(72) Inventors: PETIT, Laurent; 19, Chemin du Peylou(cid:173)
`bier, 06530 Peymeinade (FR). CHANTALAT, Laurent;
`12 Stuyvesant Oval, New York, NY, NY 10009 (US).
`
`JOMIER, Matthieu; 252 Nassau Street, Princeton, New(cid:173)
`jersey 08542 (US). VERNET, Romain; l3bis, place Jules
`Ferry, 69006 Lyon (FR). ADNET, Cyprien; l3bis, place
`Jules Ferry, 69006 Lyon (FR).
`
`(74) Agent: CABINET PLASSERAUD; 66 me de la Chaussee
`d'Antin, 75440 Paris Cedex 09 (FR).
`
`(81) Designated States (unless otherwise indicated, for every
`kind of national protection available): AE, AG, AL, AM,
`AO, AT, AU, AZ, BA, BB, BG, EH, EN, BR, BW, BY, BZ,
`CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO,
`DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN,
`HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP,
`KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME,
`MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ,
`OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA,
`SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN,
`TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
`
`(54) Title: UV DEVICE FOR EVALUATION OF SKIN CONDITIONS
`
`100
`~
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`129
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`123
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`121
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`120
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`128
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`FIG. 9
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`130
`(57) Abstract: A lighting and filtering device configured for use with a camera including at least one light source configured to emit
`light having a peak wavelength in a range between 365 nm and 44 nm, and thereby illuminate a portion of a patient's skin to produce
`a fluorescence on the portion of the patient's skin, and a filter configured to be disposed in front of a lens of the camera, the filter
`being (i) a band-pass filter configured to facilitate transmission of light having a peak wavelength in a range between 550 nm and
`750 nm therethrough, or (ii) a long-pass filter configured to attenuate light that is less than a first predetermined wavelength, the first
`predetermined wavelength being in a range of 400 nm to 450 nm.
`
`[Continued on next page]
`
`Petitioner's Exhibit 1020,
` Page 1 of 68
`
`

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`WO 2019 /092509 Al 1111111111111111 IIIIII IIIII 111111111111111 II Ill 111111111111111 IIIII lllll 11111111111111111111111
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`(84) Designated States (unless otherwise indicated, for every
`kind of regional protection available): ARIPO (BW, GH,
`GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ,
`UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ,
`TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK,
`EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV,
`MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM,
`TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW,
`KM, ML, MR, NE, SN, TD, TG).
`
`Published:
`with international search report (Art. 21 (3))
`before the expiration of the time limit for amending the
`claims and to be republished in the event of receipt of
`amendments (Rule 48.2(h))
`
`Petitioner's Exhibit 1020,
` Page 2 of 68
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`WO 2019/092509
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`PCT/IB2018/001517
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`UV DEVICE FOR EVALUATION OF SKIN CONDITIONS
`
`CROSS-REFERENCE TO RELATED PATENT APPLICATION
`
`[0001] This application claims the benefit of and priority to U.S. Provisional Patent
`
`Application No. 62/584,404, filed November 10, 2017, the entire disclosure of which is
`
`incorporated herein by reference.
`
`FIELD OF INVENTION
`
`[0002] The present disclosure generally relates to a device configured for use with a camera for
`
`capturing an image of a patient's skin.
`
`BACKGROUND
`
`[0003] Many medical treatments, whether prescription or not, are known to have significant
`
`patient compliance issues which reduce the effectiveness of the treatments. In some cases, poor
`
`patient compliance results from the patient's inability to detect or observe improvements in
`
`medical conditions even though such improvements are occurring. For example, some medical
`
`conditions do not manifest immediate or significant visual improvement despite the fact that the
`
`conditions are improving in the patient. In other cases, a patient simply has poor "consumer
`
`engagement" with the specific treatment appropriate for the patient.
`
`[0004] A Woods lamp, also known as a black-light (or black light), or ultraviolet (UV) light,
`
`is a lamp which emits long-wave (UV) light and only a small amount of visible light. A Woods
`
`lamp is helpful in diagnosing bacterial infections, including Propionibacterium acnes ( also
`
`referred to as "p. acnes"), a bacterium that causes acne. This bacterium exhibits an orange-type
`
`glow under a Woods lamp. More specifically, acne fluoresces orange-red under a Woods lamp
`
`due to the presence of propionibacteria on a person's hair follicles or skin.
`
`-1-
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`Petitioner's Exhibit 1020,
` Page 3 of 68
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`[0005] As described in U.S. Patent Publication No. 20036/0063801 ("Rubinstenn, et al."),
`
`features of a facial image of a subject may be extracted by illuminating a portion of the subject's
`
`skin using a Woods lamp. The Woods lamp may help identify an amount of acne-causing
`
`bacteria present on the portion of the subject's skin by rendering visible on the subject's skin
`
`residues, such as porphyrin, which are excreted by the bacteria. In this manner, the presence
`
`and/or amount of porphyrin present on a subject's skin is a proxy for the presence and/or amount
`
`of p-acnes. An image of the illuminated residue is captured and then analyzed to determine the
`
`presence and/or amount of p-acnes present on the subject's skin. However, Rubinstenn, et al.
`
`does not teach how to use new technologies to improve consumer engagement with treatment of
`
`a skin of the patient in order to improve patient compliance with the treatments.
`
`[0006] There is a need for a device which improves patient compliance with treatments for
`
`various skin conditions or other skin treatments by providing for good consumer engagement
`
`with specific treatment appropriate for the patient.
`
`SUMMARY OF THE INVENTION
`
`[0007] The following presents a general summary of aspects of the present disclosure in order
`
`to provide a basic understanding of the disclosure. This summary is not an extensive overview
`
`of the disclosure and is not intended to identify key or critical elements of the invention or to
`
`delineate the scope of the present disclosure. The following summary merely presents some
`
`concepts of the present disclosure in a general form as a prelude to the more detailed description
`
`provided below.
`
`[0008] According to one exemplary embodiment, a lighting and filtering device configured for
`
`use with a camera includes at least one light source configured to emit light having a peak
`
`wavelength in a range between 365 nm and 445 nm, and thereby illuminate a portion of a
`
`patient's skin to produce a fluorescence on the portion of the patient's skin, and a filter
`
`configured to be disposed in front of a lens of the camera, the filter being (i) a band-pass filter
`
`configured to facilitate transmission of light having a peak wavelength in a range between 550
`
`-2-
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`nm and 750 nm therethrough, or (ii) a long-pass filter configured to attenuate light that is less
`
`than a first predetermined wavelength, the first predetermined wavelength being in a range of
`
`400 nm to 450 nm.
`
`[0009] According to one aspect, the lighting and filtering device is configured to be physically
`
`mounted to the camera.
`
`[0010] According to another aspect, the lighting and filtering device is configured to be
`
`physically mounted to an external device that comprises the camera.
`
`[0011] According to another aspect, the external device is a cellular phone, a tablet computer, a
`
`handheld media device, a laptop computer, or a desktop computer.
`
`[0012] According to another aspect, the external device is a cellular phone.
`
`[0013] According to another aspect, the lighting and filtering device is configured to be
`
`physically mounted to the cellular phone via a magnet.
`
`[0014] According to another aspect, the lighting and filtering device also includes a housing
`
`having a first lateral side configured to extend along a first lateral side of the cellular phone, a
`
`second lateral side configured to extend along a second lateral side of the cellular phone, and a
`
`third lateral side extending from the first lateral side to the second lateral side.
`
`[0015] According to another aspect, the housing includes an annular portion, the at least one
`
`light source is located at a surface of the annular portion, and the annular portion surrounds the
`
`filter.
`
`[0016] According to another aspect, the at least one light source includes a plurality oflight
`
`sources, and the plurality of light sources are evenly distributed around the surface of the annular
`
`portion.
`
`[0017] According to another aspect, the plurality of light sources includes 8 light sources.
`
`-3-
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`[0018] According to another aspect, the lighting and filtering device also includes a battery
`
`configured to supply power to the at least one light source.
`
`[0019] According to another aspect, the lighting and filtering device also includes a processor
`
`configured to control the at least one light source.
`
`[0020] According to another aspect, the lighting and filtering device also includes a transceiver
`
`configured to allow wireless communication between the processor and an external device, such
`
`that the at least one light source is controllable by the external device via the processor.
`
`[0021] According to another aspect, the transceiver operates using a frequency-hopping
`
`technique.
`
`[0022] According to another aspect, the external device is configured to receive imaging data
`
`from the camera via the transceiver and further configured to process the imaging data.
`
`[0023] According to another aspect, the external device is further configured to determine a
`
`presence and an amount of a substance on the portion of the patient's skin based on the imaging
`
`data.
`
`[0024] According to another aspect, the external device is further configured to compare the
`
`imaging data to imaging data of a control image.
`
`[0025] According to another aspect the lighting and filtering device also includes a connector
`
`configured to allow wired communication between the processor and an external device, such
`
`that the at least one light source is controllable by the external device via the processor.
`
`[0026] According to another aspect, the connector is a USB type connector.
`
`[0027] According to another aspect, the lighting and filtering device also includes a processor,
`
`a transceiver configured to allow wireless communication between the processor and an external
`
`device, such that the at least one light source is controllable by the external device via the
`
`processor, and a connector configured to allow wired communication between the processor and
`
`-4-
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`the external device, such that the at least one light source is controllable by the external device
`
`via the processor.
`
`[0028] According to another aspect, the transceiver operates using a frequency-hopping
`
`technique, and the connector is a USB type connector.
`
`[0029] According to another aspect, the band-pass filter is configured to attenuate light that is
`
`less than a second predetermined wavelength and greater than a third predetermined wavelength,
`
`the second predetermined wavelength being in a range of 550 to 650 nm, and the third
`
`predetermined wavelength being in a range of 650 to 750 nm.
`
`[0030] According to another aspect, the first predetermined wavelength is in a range of 430 nm
`
`to 440 nm.
`
`[0031] According to another aspect, the first predetermined wavelength is 435 nm.
`
`[0032] According to another aspect, the at least one light source is configured to emit light
`
`having a peak wavelength in a range between 385 nm and 425 nm.
`
`[0033] According to another aspect, the at least one light source is configured to emit light
`
`having a peak wavelength in a range between 400 nm and 415 nm.
`
`[0034] According to another aspect, the at least one light source is configured to emit light
`
`having a peak wavelength of 405 nm.
`
`[0035] According to another aspect, the peak wavelength of light emitted by the band-pass
`
`filter is in a range between 600 nm and 650 nm.
`
`[0036] According to another aspect, the peak wavelength of light emitted by the band-pass
`
`filter is in a range between 630 nm and 640 nm.
`
`[0037] According to another aspect, the peak wavelength of light emitted by the band-pass
`
`filter is 635 nm.
`
`-5-
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`[0038] According to another aspect, wherein the band-pass filter is configured to facilitate
`
`transmission oflight having a full width at half maximum in a range of 70 nm to 130 nm
`
`therethrough.
`
`[0039] According to another aspect, the lighting and filtering device comprises the camera.
`
`[0040] According to another aspect, the lighting and filtering device also includes a black
`
`housing.
`
`[0041] According to one exemplary embodiment, a method of diagnosing p-acnes using an
`
`external device and a lighting and filtering device, the external device including a processor and
`
`a camera and the lighting and filtering device including a light source configured to emit a light
`
`having a peak wavelength in a range between 365 nm and 445 nm, the lighting and filtering
`
`device configured to be connected to the external device, the method including connecting, by a
`
`user, the lighting and filtering device to the external device, positioning, by a user, the lighting
`
`and filtering device adjacent a target area of a user's skin, emitting, by the lighting and filtering
`
`device, the light onto the target area, and determining, by the processor, whether the target area
`
`contains any p-acnes.
`
`[0042] According to one aspect, the method further includes obtaining, by the camera, an
`
`image of the target area while the light is emitted onto the target area.
`
`[0043] According to another aspect, the method further includes instructing, by the processor,
`
`the camera to obtain the image, where the processor does not instruct the camera to obtain the
`
`image until the light has been emitted onto the target area for a target amount of time.
`
`[0044] According to another aspect, the method further includes determining, by the processor,
`
`whether each pixel of the image has an attribute that is above an attribute threshold.
`
`[0045] According to another aspect, the attribute is a red component of the pixel.
`
`-6-
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`[0046] According to another aspect, the method further includes recording, by the processor,
`
`each pixel that has an attribute that is above the attribute threshold.
`
`[0047] According to another aspect, the method further includes calculating, by the processor,
`
`an area percentage for the image by comparing a total number of pixels for the image and a
`
`number of pixels for which the attribute is above the attribute threshold.
`
`[0048] According to another aspect, the method further includes calculating, by the processor,
`
`an area score by comparing the area percentage to an area percentage threshold.
`
`[0049] According to another aspect, the method further includes calculating, by the processor,
`
`an area score for the image by comparing the area percentage and an area percentage threshold
`
`and correlating, by the processor, the area score to a plurality of area score ranges to determine if
`
`the target area contains any p-acnes.
`
`[0050] According to another aspect, the method further includes calculating, by the processor,
`
`an average fluorescence for the image.
`
`[0051] According to another aspect, the method further includes displaying, by the external
`
`device, the image, the area score, and the average fluorescence.
`
`BRIEF DESCRIPTION OF THE DRAWINGS
`
`[0052] The accompanying drawings are not intended to be drawn to scale. Like reference
`
`numbers and designations in the various drawings indicate like elements. For purposes of
`
`clarity, not every component may be labeled in every drawing. In the drawings:
`
`[0053] FIG. 1 is a front perspective view of a lighting and filtering device configured for use
`
`with a camera, according to one exemplary embodiment.
`
`[0054] FIG. 2 is a front perspective view of a lighting and filtering device configured for use
`
`with a camera, similar to the lighting and filtering device configured for use with a camera
`
`shown in FIG. 1.
`
`-7-
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`[0055] FIG. 3 is a front cross-sectional perspective view of the lighting and filtering device
`
`configured for use with a camera shown in FIG. 2.
`
`[0056] FIG. 4 is a front perspective view of a lighting and filtering device configured for use
`
`with a camera, according to a second exemplary embodiment.
`
`[0057] FIG. 5 is a front perspective view of a lighting and filtering device configured for use
`
`with a camera, according to a third exemplary embodiment.
`
`[0058] FIG. 6 is a rear perspective view of the lighting and filtering device configured for use
`
`with a camera shown in FIG. 5.
`
`[0059] FIG. 7 is a graph illustrating an internal transmittance of a 435 nm long-pass filter
`
`useable with a lighting and filtering device configured for use with a camera.
`
`[0060] FIG. 8 is a graph illustrating a transmission rate for wavelengths of light of a 630 nm
`
`band-pass filter useable with a lighting and filtering device configured for use with a camera.
`
`[0061] FIG. 9 is a front perspective view of an assembly including the lighting and filtering
`
`device configured for use with a camera shown in FIG. 1 mounted on a cellular phone.
`
`[0062] FIG. 10 is a rear perspective view of the assembly shown in FIG. 9.
`
`[0063] FIG. 11 is a schematic illustrating components of an external device on which the
`
`lighting and filtering device configured for use with a camera, shown in FIG. 1, is mountable.
`
`[0064] FIG. 12 is a front perspective view of the lighting and filtering device configured for
`
`use with a camera shown in FIG. 1, according to one aspect.
`
`[0065] FIG. 13 is a front perspective view of the lighting and filtering device configured for
`
`use with a camera shown in FIG. 4 mounted on a cellular phone.
`
`[0066] FIG. 14 is a rear view of the assembly shown in FIG. 13.
`
`-8-
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`[0067] FIG. ISA is a photograph showing an image captured by a camera of a handheld media
`
`device.
`
`[0068] FIG. 15B is a photograph showing an image captured by the camera of a handheld
`
`media device using the lighting and filtering device configured for use with a camera shown in
`
`FIG. 2.
`
`[0069] FIG. 16A is a photograph showing an image captured by a camera of a cellular phone.
`
`[0070] FIG. 16B is a photograph showing an image captured by a camera of the cellular phone
`
`using the lighting and filtering device configured for use with a camera shown in FIG. 2.
`
`[0071] FIG. 17 is a photograph showing an image captured by a camera of a cellular phone
`
`using the lighting and filtering device configured for use with a camera shown in FIG. 2.
`
`[0072] FIG. 18 a photograph showing an image captured by a camera of a cellular phone using
`
`the lighting and filtering device configured for use with a camera shown in FIG. 2.
`
`[0073] FIG. 19 is a block diagram of a process for analyzing p-acnes on a user's skin.
`
`[0074] FIG. 20 is a photograph showing an image captured by a camera of a cellular phone
`
`using the lighting and filtering device configured for use with a camera shown in FIG. 2.
`
`[0075] FIG. 21 a photograph showing an image captured by a camera of a cellular phone using
`
`the lighting and filtering device configured for use with a camera shown in FIG. 2.
`
`[0076] FIG. 22 is a front perspective view of a lighting and filtering device configured for use
`
`with a camera and having a blocking tube, according to one exemplary embodiment.
`
`[0077] FIG. 23 is a side perspective view of the lighting and filtering device configured for use
`
`with a camera shown in FIG. 22.
`
`-9-
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`[0078] FIG. 24 is a rear perspective view of the lighting and filtering device configured for use
`
`with a camera shown in FIG. 22.
`
`[0079] FIG. 25 is a detailed view of the lighting and filtering device configured for use with a
`
`camera shown in FIG. 22.
`
`[0080] FIG. 26 is a photograph showing an image captured by a camera of a cellular phone
`
`using the lighting and filtering device configured for use with a camera shown in FIG. 22.
`
`[0081] FIG. 27 a photograph showing an image captured by a camera of a cellular phone using
`
`the lighting and filtering device configured for use with a camera shown in FIG. 22.
`
`[0082] FIG. 28 a photograph showing an image captured by a camera of a cellular phone using
`
`the lighting and filtering device configured for use with a camera shown in FIG. 22.
`
`[0083] FIG. 29 is a front view of a blocking tube configured for use with a lighting and
`
`filtering device, according to one exemplary embodiment.
`
`[0084] FIG. 30 is a cross-sectional view of the blocking tube shown in FIG. 29 taken about
`
`plane A-A.
`
`[0085] FIG. 31 is a bottom view of the blocking tube shown in FIG. 29.
`
`[0086] FIG. 32 is a rear view of the blocking tube shown in FIG. 29.
`
`DETAILED DESCRIPTION
`
`[0087] The description below relates to a lighting and filtering device configured for use with a
`
`camera. The lighting and filtering device configured for use with a camera is configured to
`
`provide imaging of a portion of a patient's skin and determine a level ( e.g., an intensity, a
`
`density, etc.) of fluorescence illuminating the portion of the patient's skin. The lighting and
`
`filtering device configured for use with a camera thereby effectively and efficiently
`
`communicates information regarding the portion of the patient's skin such that the patient can
`
`-10-
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`determine an effectiveness of treatment for the patient's skin. Accordingly, patient compliance
`
`with the treatment is facilitated.
`
`[0088] The lighting and filtering device configured for use with a camera (such as a device for
`
`providing imaging of a patient's skin or device for evaluating a skin condition of a patient)
`
`herein disclosed is configured to assist a patient in determining an effectiveness of skin treatment
`
`by, for example, determining an existence or amount of a substance present on the skin of the
`
`patient. For example, the lighting and filtering device configured for use with a camera is
`
`useable in determining an existence and/or amount of a substance on the patient's skin indicative
`
`of a state and/or extent of a skin condition. A skin condition includes, but is not limited to,
`
`increase in pigmentation ( e.g., melasma, postinflammatory pigmentation, etc.), loss of
`
`pigmentation ( e.g., Vitiligo, ash-leaf macules in tuberous sclerosis, and hypomelanosis oflto ),
`
`pityriasis versicolor, malassezia folliculitis, tinea capitis, head lice, scabies, erythrasma,
`
`pseudomonas (wound infection), acne ( e.g., p. acne), poryphia, presence of porphyrins,
`
`photodamage, and actinic keratosis. As an additional example, the lighting and filtering device
`
`configured for use with a camera is useable in determining an existence and/or amount of a
`
`substance on the patient's skin that is unrelated to a skin condition of the patient, for example, a
`
`presence and/or amount of sun screen applied to a portion of the patient's skin or application of
`
`salicylic acid ( e.g., application of chemical peel) on a portion of the patient's skin.
`
`[0089] Acne, particularly p. acne, is particularly prone to poor patient compliance and
`
`consumer engagement of treatment for the acne. One type of acne treatment involves applying a
`
`topical product to the acne, such as a product that includes as an active ingredient benzoyl
`
`peroxide. A severity of p. acne can be determined based on a presence and amount of porphyrin
`
`present on a patient's skin because the bacteria which cause p. acne excrete porphyrin.
`
`[0090] As shown in FIGS. 1-3, herein disclosed is a device 1 (e.g., a lighting and filtering
`
`device configured for use with a camera). In some implementations, the device 1 is configured
`
`to be physically mounted to the camera. In some implementations, the device 1 is configured to
`
`be mounted by any suitable means to an external device that includes a camera. The external
`
`-11-
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`device may be a computing device such as a cellular phone ( e.g., smartphone, etc.), a tablet
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`computer, a handheld media device, a laptop computer, or a desktop computer. The device 1 is
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`configured to illuminate a portion of a patient's skin to facilitate imaging the portion of the
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`patient's skin so that a presence and/or amount of a substance (for example, a substance secreted
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`by bacteria that cause acne) present on the portion of the patient's skin can be detected and
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`determined, thereby allowing for the patient to determine or visualize an effectiveness of
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`treatment of the patient's skin.
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`[0091] Referring to FIGS. 1-2, the device 1 includes a housing (e.g., case) 5 which includes a
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`front, closed surface 6 and a back, open surface 7 (shown in FIG. 3). Referring to FIGS. 1-3, the
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`housing 5 is made of any suitable material, for example, molded plastic or metal, such that the
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`housing 5 is configured to be mounted to a computing device. As one example, the device 1 is
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`configured to be physically mounted to an external device via a magnet. In other examples, the
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`device 1 may be configured to be physically mounted to an external device via adhesive (e.g.,
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`fugitive glue, double sided adhesive, etc.) or via a hook and loop fastener (e.g., Velcro, etc.). In
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`still other examples, the device 1 may be configured to be physically mounted to an external
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`device via fasteners ( e.g., snap members, clasps, bolts, etc.). The housing 5 is of any suitable
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`size or shape, for example, a size or shape for mounting device 1 onto at least one side of an
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`external device (e.g., a cellular phone) so that the device 1 is used in conjunction with the
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`external device (as described below) without adversely affecting the patient's ability to use the
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`external device. For example, the housing 5 includes a first lateral side (e.g., a right side) 8
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`configured to extend along a first lateral side 128 of an external device 120 (shown in FIG. 9),
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`which is, in this case, a cellular phone. As shown in FIG. 1, the housing 5 also includes a second
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`lateral side (e.g., left side) 9 configured to extend along a first lateral side 129 of an external
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`device 120 (shown in FIG. 9). As shown in FIG. 1, the housing 5 also includes a third lateral
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`side ( e.g., bottom side) 10 extending from the first lateral side 8 to the second lateral side 9 of the
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`housing 5.
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`[0092] According to one example, the housing 5 is colored black ( e.g., by painting the housing
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`5 with a black paint, dying the housing 5 black, or other suitable coloration process) to avoid
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`-12-
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` Page 14 of 68
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`PCT/IB2018/001517
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`external light reflection off of the housing 5 when the device 1 is in use. As a specific example,
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`the housing 5 is formed of molded black plastic.
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`[0093] As shown in FIG. 3, the housing 5 includes a recess or opening 15 configured to house
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`a power button 20 (shown in FIG. 1) for controlling an electric power provided to the device 1
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`(for example, a button for turning the device 1 on or off). The housing 5 also includes a recess or
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`opening 16 configured to house a hub or plug for connecting the device 1 to an electric power
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`supply or to house a USB type connector. For example, the recess 16 is a port configured to
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`receive a USB type connector 25 configured to provide a wired connection between the device 1
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`and an external device (such as the external device 120 shown in FIGS. 9-10) and/or an external
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`power source.
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`[0094] The housing 5 also includes an annular portion 30. The annular portion 30 is of any
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`suitable size. The annular portion 30 is configured to house or support at least one lighting
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`element, such as at least one light source 40 or filter 45. As shown in FIG. 3, the annular portion
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`30 includes a surface 31 configured to support the at least one light source 40 and/or the filter 45.
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`The surface 31 has a circular cross section and is configured to be received into an interior region
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`32 of the annular portion 30 (for example, the interior region 32 of annular portion 30 defined by
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`an outer circumference and an inner circumference of annular portion 30). The annular portion
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`30 is configured to hold the at least one light source 40 (described below) at the surface 31 and is
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`further configured to surround the filter 45. As shown in FIG. 1, the annular portion 30 is
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`disposed on the first lateral side 8 of the housing 5, but the annular portion 30 is not limited to
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`this particular orientation. For example, as shown in FIGS. 2-3, the annular portion 30 is
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`disposed on the second lateral side 9 of the housing 5.
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`[0095] Referring back to FIG. 1., the at least one light source 40 is, for example, a Woods lamp
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`for providing UV light and of a size appropriate for mounting on an external device ( e.g., cellular
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`phone, etc.). The at least one light source 40, in some implementations, includes a plurality of
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`light sources 40 which are evenly distributed around the surface 31 of the annular portion 30 of
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`the housing 5. Although FIG. 1 shows eight light sources distributed along a circumference of
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`-13-
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` Page 15 of 68
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`PCT/IB2018/001517
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`the annular portion 30, the at least one light source 40 is not limited to this particular example.
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`According to one example, the at least one light source 40 includes one light source. According
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`to another example, the at least one light source 40 includes two, three, four, five, six, seven, or
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`eight light sources. According to a still another example, the at least one light source 40 includes
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`more light sources, such as sixteen light sources, thirty-two light sources, or sixty-four light
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`sources.
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`[0096] As one specific example, the at least one light source 40 is a light emitting diode (LED)
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`In a particular example, the at least one light source 40 is a UV flash light. The at least one light
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`source 40 is configured to emit light having a predetermined wavelength, for example, light
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`having at least a component of UV light (e.g., light having a wavelength of between 100 nm and
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`400 nm). As another example, the at least one light source 40 emits light having a wavelength
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`outside the UV wavelength ranges to avoid damaging a skin of a patient using the device 1.
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`Specifically, the at least one light source 40 is configured, for example, to emit light having a
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`peak wavelength in a range between 365 nm and 445 nm. Preferably, the at least one light
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`source 40 is configured to emit light having a peak wavelength in a range between 385 nm and
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`425 nm. More preferably, the at least one light source 40 is configured to emit light having a
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`peak wavelength in a range between 400 nm and 420 nm. More preferably, the at leas