Filed July 22, 2003

Serial No. 78277322

Registered Dec. 26, 2006

Registration No. 3,188,634

Class Clinical trial supplies management services, namely-customized drug packaging and labeling, central and site administered randomization and study supply distribution; developing and managing distribution and storage logistics for all clinical supplies, namely study drugs and devices, case report forms, study binders and all study related documentation; clinical trial management services, namely-pre-study document collection and review, site selection, pre-study site visits, initiation visits, monitoring visits, close-out visits, project tracking and monitoring reports, negotiation and administration of investigator grants, labeling, packaging, distribution, coordination and tracking of clinical trial materials, regulatory document processing, central laboratory selection and coordination; managing site and study-specific subject recruitment strategies and programs, namely contingency strategies and solutions to address specific project challenges; managing the development of all study related documents and materials, namely study protocols, amendments, paper and electronic case report forms, and informed consent forms; managing study operations/monitoring manuals in accordance with data management conventions, web-based data listings, namely adverse events, enrollment status, efficacy endpoints and paper and electronic study newsletters; management of tracking tools for enrollment, essential documents, monitoring, subject and case report form tracking, drug accountability, data queries and adverse events; managing all aspects of study drug reconciliation and inventory and distribution reports; managing all aspects of clinical trials, namely managing investigators, technicians, and participants, ethical reviews, investigator meetings, databases, statistical analyses and reporting, randomization logistics, medical writing services; recruitment of investigators, technicians and participants; providing strategies for recruitment of participants; 100; 101; 102; 100; 101; 107; 100; 101

Case Type Service mark