(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT)
`
`(19) World Intellectual Property Organization
`International Bureau
`
`(43) International Publication Date
`29 January 2009 (29.01.2009)
`
` (10) International Publication Number
`
`W0 2009/01527 4 A2
`
`(51) International Patent Classification:
`C08F 36/02 (2006.01)
`A61K 31/74 (2006.01)
`C08K 11/00 (2006.01)
`
`(74) Agents: SALIWAN CHIK, David, R. et al.; Saliwanchik,
`Lloyd & Saliwanchik, A Professional Association, PO.
`Box 142950, Gainesville, FL 32614—2950 (US).
`
`(21) International Application Number:
`PCT/US2008/071020
`
`(22) International Filing Date:
`
`24 July 2008 (24.07.2008)
`
`(25) Filing Language:
`
`(26) Publication Language:
`
`(30) Priority Data:
`60/951,666
`
`English
`
`English
`
`24 July 2007 (24.07.2007)
`
`US
`
`(71) Applicant (for all designated States except US): UNI-
`VERSITY OF FLORIDA RESEARCH FOUNDA-
`
`TION, INC. [US/US]; 223 Grinter Hall, Gainesville, FL
`32611 (US).
`
`(72) Inventors; and
`(75) Inventors/Applicants (for US only): LEONARD, James,
`Klein [US/US]; 2145 SW. 72nd Street, Gainesville, FL
`32607 (US). WAGENER, Kenneth, Boone [US/US];
`5012 N.w. 15th Place, Gainesville, FL 32605 (US).
`
`(81) Designated States (unless otherwise indicated, for every
`kind of national protection available): AE, AG, AL, AM,
`AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA,
`CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE,
`EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID,
`IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK,
`LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW,
`MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT,
`RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ,
`TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM,
`ZW.
`
`(84) Designated States (unless otherwise indicated, for every
`kind of regional protection available): ARIPO (BW, G1 I,
`GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM,
`ZW), Eurasian (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM),
`European (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI,
`FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL,
`NO, PL, PT, RO, SE, SI, SK, TR), OAPI (BF, BJ, CF, CG,
`CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
`Published:
`
`without international search report and to be republished
`upon receipt of that report
`
`(54) Title: POLYETHYLENE BASED BIOACTIVE AGENTS
`
`(57) Abstract: The present invention concerns an acyclic diene metathesis (ADMET) chemistry— based method of making polymers
`incorporating biologically active molecules, and the polymers formed thereby. Functionalized polymers prepared by this method
`can be used to produce a broad range of commercially important products such as drag delivery agents (prodrugs), chromatography
`reagents (e.g., for use in separatory reagents), biomimetics, and biodegradable synthetic polymers.
`
`
`
`W02009/015274A2|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
`
`