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2
`
`In the Claims
`
`Docket No. UF.572XC1
`
`Serial No. 12/664,172
`
`
`moneme-rsmonomer units. each. of the repeating diene monomer units having coupled thereto at
`
`least one biologically active molecule through at least one non-amide linkerr—wéltereinig a
`
`
`carbons massages
`f
`.
`
`
`
`‘ ol the Repeatingr diene monomm unit “herein the carbons coupled to the
`
`biologicall active molecule of the adjacent repeating diene monomer units are separated by
`
`2n+2 other carbons
`
`
`
`‘ ' me, where n is the number of alkvlene carbons1n
`
`each of two alkylene carbon backbone spacers residing between each ene and the carbon coupled
`
`
`to the biologicallv agtige molecule oflthe repeatin11gglj§ne monome1 unit '
`
`2. (previously presented) The polymer of claim 1, wherein the linker comprises at least
`
`one moiety selected from the group consisting of an ester, carbonate, carbamate, and ether.
`
`3. (previously presented) The polymer of claim 1, wherein the at least one moiety is an
`
`ether moiety and a carbamate moiety.
`
`4.
`
`(currently amended) The polymer of claim 1, wherein the repeating diene monomer
`
`1111i; is selected from the group consisting of 3,3 acid, 6,6 acid, 9,9 acid, and 18,18 acid.
`
`5.
`
`(currently amended) The polymer of claim 1, wherein therrepeating diene monomer
`
`111111 further comprises at least one spacer interposed between the biologically active molecule
`
`and the linker.
`
`6.
`
`(original) The polymer of claim 5, wherein the spacer is at least one moiety selected
`
`from the group consisting of methoxy and glycol.
`
`7.
`
`(original) The polymer of claim 6, wherein the spacer is at least one ethylene glycol
`
`J :\UF\572XC 1\Amend\Amend-Final.docx/ps
`
`

`

`moiety.
`
`3
`
`Docket No. UF.572XC1
`
`Serial No. 12/664,172
`
`8.
`
`(original) The polymer of claim 6, wherein the spacer is diethylene glycol or
`
`triethylene glycol.
`
`9. (previously presented) The polymer of claim 5, wherein the spacer is at least one alkyl
`
`or diol moiety.
`
`10.
`
`(previously presented) The polymer of claimS, wherein the at least one linker, the at
`
`least one spacer, or both are degradable by enzymatic cleavage, chemical hydrolysis, or both.
`
`11.
`
`(previously presented) The polymer of claim 1, wherein the biologically active
`
`molecule is selected from the group consisting of analgesics, anesthetics, anti-inflammatory
`
`agents, anthelmintics, anti—arrhythmic agents, antiasthma agents, antibiotics, anticancer agents,
`
`anticoagulants, antidepressants, antidiabetic agents, antiepileptics, antihistamines, antitussives,
`
`antihypertensive agents, antimuscarinic agents, antimycobacterial agents, antineoplastic agents,
`
`antioxidant agents, antipyretics,
`
`immunosuppressants,
`
`immunostimulants, antithyroid agents,
`
`antiviral agents, anxiolytic sedatives (hypnotics and neuroleptics), astringents, bacteriostatic
`
`agents, beta—adrenoceptor blocking agents, blood products and substitutes, bronchodilators,
`
`buffering agents, cardiac inotropic agents, chemotherapeutics, contrast media, corticosteroids,
`
`cough suppressants (expectorants and mucolytics), diagnostic agents, diagnostic imaging agents,
`
`diuretics, dopaminergics (antiparkinsonian agents),
`
`free radical scavenging agents, growth
`
`factors, haemostatics, immunological agents, lipid regulating agents, muscle relaxants, proteins,
`
`peptides and polypeptides, parasympathomimetics, parathyroid calcitonin and biphosphonates,
`
`pesticides, prostaglandins, radio-pharmaceuticals, hormones, sex hormones (including steroids),
`
`time release binders, anti-allergic agents, stimulants and anoretics, steroids, sympathomimetics,
`
`thyroid agents, vaccines, vasodilators, and xanthines.
`
`12.
`
`(original) A pharmaceutical composition comprising a polymer of claim 1; and a
`
`pharrnaceutically acceptable carrier.
`J :\UF\5 72XC1\Amend\Amend-Finaldocx/ps
`
`

`

`4
`
`Docket No. UF.572XC1
`
`Serial No. 12/664,172
`
`13. (withdrawn) A method for making a polymer of claim 1, comprising providing diene
`
`monomers coupled to at least one biologically active molecule through at least one non-amide
`
`linking moiety (linker); and polymerizing the monomers to produce the polymer.
`
`14.
`
`(withdrawn) The method of claim 13, wherein said providing comprises coupling
`
`the at least one biologically active molecule to the diene through at least one linker.
`
`15.
`
`(withdrawn) A method for delivering a biologically active molecule to a subject,
`
`comprising administering a polymer of claim 1 to the subject.
`
`16. (withdrawn) A device comprising a polymer of claim 1.
`
`17.
`
`(withdrawn) The device of claim 16, wherein the device comprises one or more
`
`substrates (surfaces) coated with the polymer or coated with a composition comprising the
`
`polymer.
`
`18.
`
`(withdrawn) The device of claim 16, wherein the device is an implantable or
`
`deployable medical device.
`
`J :\UF\572XCIMmendmmend—Finaldocx/ps
`
`

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