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`WO2011/083850AIMAUUATNATTA
`
`(74)
`
`(54) Title: ANTISTATIC AGENT AND RESIN COMPOSITION CONTAINING SAME
`
`(54) EROS: PEMILAIRUEHEBAS Siti
`
`(57) Abstract: Disclosed are an antistatic agent, which can sustain antistatic properties over a long period of time and does not
`damage the appearanceor transparency of a resin when incorporated therein, and a resin composition containing the same. Specif-
`ically disclosed are: an antistatic agent comprising a block copolymer which is obtained from a product of a reaction between a
`polyolefin (a) having been acid-modified at one end and a diol and/or diamine (b) having a polyoxyalkylene chain, and in which
`some or all of acid groups remaining in the reaction product have been neutralized with an alkaline substance; a thermoplastic
`resin composition containing said antistatic agent; and a film or sheet formed of said thermoplastic resin composition.
`(57) a9: [ERA] EARS Ro CT AP TE eitL HABIT ARY AA CHEE ONPIB FIRE
`UmEeILAIRUCKNESAS SBMMeRRS S0e. | (RSH) Ca) FRMAERSIES 1
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`WO 2011/083850
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`1
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`PCT/JP2011/050194
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`WO 2011/083850
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`2
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`PCT/JP2011/050194
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`

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`WO 2011/083850
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`3
`
`PCT/JP2011/050194
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`
`

`

`WO 2011/083850
`
`4
`
`PCT/JP2011/050194
`
`(HAL RUKYA—ILA’ 6 KR ART REE, AIL RRR 2~ 4 D7 IX
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`

`

`WO 2011/083850
`
`5
`
`PCT/JP2011/050194
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`

`

`WO 2011/083850
`
`6
`
`PCT/JP2011/050194
`
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`
`

`

`WO 2011/083850
`
`7
`
`PCT/JP2011/050194
`
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`
`

`

`WO 2011/083850
`
`8
`
`PCT/JP2011/050194
`
`[0024]
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`[
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`
`

`

`WO 2011/083850
`
`9
`
`PCT/JP2011/050194
`
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`8
`
`—DAFILIFILF BY, 2-FEBINTIEY, B-FREINIEAY VD
`
`AAV FILG BY, AEVILVP BY, VOAREVILE BY, ADFILIT SE
`
`VY. JZILDP BY, TUN EY, DUTUIVF BY, FTUILT SUS)
`
`DEAE FOV STILE IMLRORRRFM 621 2DRSR—RMES
`
`FRY (FLU Y, AVUILF SYS) OEAE FOXY ST ILSIVEMAS
`
`fon.
`
`CNnbYAIWHESMOHCH, BELLS (SRO LA LRU
`
`EFADTS—ILCHY. RICHELLE LFLY AVA)RUEAII
`
`J—NACHS.
`
`[0027]
`
`He A IMLS BMICAMSHSPILELU ALY FELTIA, RHR
`
`FR2ABZ4OF WEL UATE, HAIL, DFLYALGH FL Fo
`
`ELUASHT FL FDFUV ALU FASB oN, CONDO 1M 2
`
`VALE aT SCEMCES. FILELUASH ST FORME, BAIS IL
`
`A ' fRROGER. 100~200COHRECHES.
`
`[0028]
`
`SIO. ASEAAICTHUYT. Cb) RYU L—PFILVA— IVE UT HBIT AALS
`
`NE*ADELTIA, DFBSOCOMBZ2, OOOD, KYRELSKIE500
`
`HB1, OOONKRYLFLYAYA-IRNAERADLSY—-WADLIFLY
`
`ALOT FHMMEBIFSCEMRCES.
`
`[0029]
`
`Kte, WER DC—-TPILY FS VMIk, BAAR T—-TILYA—IOe FA
`
`

`

`WO 2011/083850
`
`10
`
`PCT/JP2011/050194
`
`HVAREDBAMOARICEUVP S/RICBMITSCEICEY RSH, HlAIE—
`
`fest: H,N—A’ — (OA) m—O—R—-O-— (AO) n—-A’ —-NH, CR
`
`SHEILEMMEBIFonS. MHA, RL AL mMRUn (SARK T—TILY
`
`AIL CEIFTTEDERMRCHY, A’
`
`(tRRRPRM2MBZL4OVILELY
`
`BERT.
`
`[0030]
`
`[PFOvyZ7ZRESMIEI
`
`AFHAICROEPAOYOHBSAS. BE (a) ARAB SNERY
`
`ALI4 VERE (b) RUALVLIPILELVUHeaTS57—-IRVUYR
`
`AVF SVEORIMD Son, BREMRILRET SBBO—-MBEL<
`
`(LERATILAUEMBICKYRPMAENTHSCESHMETS. HAIL (
`
`a) MARimeRKY LT VBRCHRELERUAL IV CHS, KI
`
`HAyDREAA (a) & (b) ERISHSCET (a) PORKYVET
`
`VE AROBil, RAT STEBOD DILARYL ILEMT ILA UIEDMS
`
`ICkEaDTPA SHIREL CE ON—DLATIVERS.
`
`[0031]
`
`(a) AmmARBIESHMERUAL IA VE (b) RUAFLVIILEL
`
`VIRAAT SVA—ILRUY REVS SVEORIMISHROREF. 150
`
`~250CCHAICEACEHS. ARIA CHDCTETILA ARE CH
`
`DCHKWA, ENKEEBBOPMICE MLS CEMCESACTFILA |) ih
`
`bEASEFE LLY, FILA) HEE LT, EROBBZOPHOLOIMEAT S
`
`FUAVEMBE UCTHITSAO SHILA CES.
`
`Kt, Lachheee OC, SPIE P VD FEV REOP VU FEV RAM: EV
`
`PFIAZRALY FREDAZAARARE | ThKODFILFAR—-bFREDFS
`
`Vane > TKO PDFIVVIVIAKA—bFKREOV ILIAD ARE> BFERUIL
`
`I=J)L, BRERA COARSEBBA: RBRVS DOLL TF hOER
`
`(KUDTAILRAD AY) NIVIOLEEOKRIVIOARERE > RON
`
`5D 2ZEALOMABHEEAUTHEHLL.. CHhODIHMELWEDIE,
`
`VILVA=~VARIERUAREBSE Bis KARE CHU. RICHELLE OILH
`
`BO)LI-/LCHS. CNDKLIGARFRIRAMRSEAT SMlt, RR
`
`

`

`WO 2011/083850
`
`14
`
`PCT/JP2011/050194
`
`BOF ILA VEMBRBI-KSANLEADESERY, PMLBLIOyIOHRE
`
`BAO RIGRIIFOTERBUL, RIBRICT OTHER. GECCCHLS
`
`NOEFSWMAUEMB LIL, ROBT SBEROPAOKOIMEAT STIL
`
`AVEMBE UCHITS EO SMMIL EA CES.
`
`(a) AmRimABEHESHERUALI AVE (b) RUAFEYVIILEL
`
`VHEATSVA—-IVRUY REY 5 VORIGEIS (THRICE SNELAS
`
`. BMD (A) — (B) — (A) BOFOYITREBERASMBKXK ESRC
`
`EJLIEE (a)
`
`:
`
`(Cb) =2: 1TICILMEERPELL,
`
`[0032]
`
`RETEST SBREOPAOKLOIEAT SP ILAUIEMBELTIZ, UFUL
`
`,AYIL, FRUDLEOT ILA) SROKRILMPRBIB, DILYIL
`
`. VIRVIOLSOS NAV THER OKBiLwM PRB. TVET. A
`
`HIF SVSRUCNHSD 246ULOHAMSIT 6nd.
`
`BURMUITILIAKFaMEF UDA. OKSHMEDA UDA, AKRMEDAILY OA, Fh
`
`WObDREY EL FRUDLAREY FL FRUDAter t—-—FAkeY
`
`FL AUDAtert—-DhEVE, n-PFILUFDL, sec-—TFIL
`
`YFOL, VFUVAVAYVPOPWP SFL FRUDASFSE KF. UFUAE
`
`ARUAFILYUILE S FL REIT RKUDL, RBRAUODL, RBKRT
`
`DL. RERAKRA DL. OKERIEU FOL, ARBRE F RUD, OKERILA
`
`WoL, 7KEMEINU DL, TKERIEDILY OL, J VERT BUDA,
`
`UD VBA
`
`WoL, YURBAILY DL, MRT FKUDL, RRA UDL, FRI RUD
`
`A, FREBDU OL, RRV DRDO L, TIBI FUDD, OT RBUFOL
`
`~ KURURUD, DLFUV VP ELT ROBT RUD LAY SF
`
`NOR BRST RK UDA, NS KILEY AILRUBFhUDAL NS bILE
`
`VAILRVYBAUDL, AAW RKUDL, DOVBRF FUL, OLY
`
`BAYDA, LFLUYSY 5 VORB hKUDAL, SRY OSBFU
`
`A, ERPAXYVIFIVDLFL UY SVS bh UDA, VLFEV EY
`
`FS VARI bKUDA, DOV ILORRT RUD, FART RUD
`
`SEARS SBMNCESMCOMY CEL.
`
`

`

`WO 2011/083850
`
`12
`
`PCT/JP2011/050194
`
`CONE PF ILAUVEMRODI6, PEWLENDATCAUDL, FFKUDLS
`
`DF ILA) FBOKBMIEMAGE LL.
`
`ERT ILA VEMRIXCKSPMLBICKk CHEK L CU SREOSIA
`
`lk, BF LD (a) ARimOBEESHMERUALIAVE (b) MUAH
`
`VI ILA LViBZAT OSVA—ILRUY RLV SE VORMGEILRAT OB
`
`BEOFCCE<S THEWA, BHEMILHOATE 3 OLIMUALAHELS.
`
`SOEMMALEMKUGELLY. KERFTSREBEFEKVY SC PAT SEO
`
`[X, FILA UVEMEBILRET SBAICM LT 10 OSI MAEM ADT SSA
`
`C#S. HASISRAT SBEBIOMLTIO~2ZOOLILMAHBELSL KE
`
`YRFELKILSO~ 150 £IMCHY, BICHELSIESO~ 1004/1
`
`%CHS. ZH. CORP SHLAE THAT SES, FU- FFU
`
`ORO TH OI, ARLBER, MEAT SSCP ILA ViEMHOIS6EB
`
`BANE RAT SC EAE LLY.
`
`[0033]
`
`RIFT SREORAMGPMAKECTSA,
`
`(1) HiARHO VILA UD
`
`BeAn, Aime eERICHAT SAR,
`
`(2) RELRUAL I UO
`
`BEA BA OTe RIC VILA UIEMR ERAT SAR.
`
`(3)
`
`(a) BUALD
`
`ave (b) RUALYV PILE LUVBEATSVA—-IRVUY RAVI SY
`
`ORME LPM SABMEFSNS. PEL. FILA EMS = fk
`
`BEL TCHUSCEMCESCEDH,
`
`(a) E (b) ORGMIIX PATS
`
`~ TEPE,
`
`(1) HIARICPILAUEMBEANSAAMBELLY. FIL
`
`AVEMBABAT SABIL, TOHEANTERUWL, KMRILABABMBIX
`
`BMS CHMRAGTHERL, PARIEDETO LOT EHMSHELKSC [EI
`
`RitABSIT SECHERT SC EMDBELLY,
`
`[0034]
`
`Alec FOvyOHBAALECTIZ,
`
`(A) Hit (a) AARMASREH SNE
`
`MRUALIA 4 VICHRTSAPOYVE,
`
`(B) Wi (b) MUAY TV ILS
`
`LYGeAt S°A—-—ILRUY RAYS SUMITHRIFSIFOYVIEM,
`
`(A
`
`) — (B) — (A) #RIE (A) — (B) HIcMALEBBFAT SIO
`
`DRE GAM, RIC,
`
`(A) — (B) — (A) BHRBOP OY DRESA
`
`

`

`WO 2011/083850
`
`13
`
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`
`Aa IbAbEL<LY— bOMA PIBSIRG DRA CHELLY. CHEs
`
`»
`
`(A) — (B) — (A) BOF Oy PRE BAMERO EA THEEE
`
`He. BATFE ILAIOPRMCATEEALTHAY, EARTHSE
`
`IFFIDMBCHOEPAYU—KFDFOMBEAKS LOD, BATH SEMI
`
`RIK Y SiH eC OFIBEIENOSELOCHEEBAH5NS.
`
`[0035]
`
`(A) — (B) — (A) #OF7OvyI7HBSSARE UTA, FitCR
`
`SHEPOYVIHESAMBENS.
`
`[4E6]
`
`R2
`
`O
`
`O
`
`OM
`MO
`(OA)m—- O- R'-O-(AO) n
`
`O
`
`O
`
`R3
`
`(1)
`
`bath, RUKVYA—ILASE FOV RARERER, Ald
`
`2TBADS WAL VAR, m,. nlkenNEnNMULT1IE1 OOD,
`
`R2, RISKUALI 4 VRE, MLV ILA SB. FILA UV ARMS. FV
`
`EAVLMILART VEADLERT.
`
`[0036]
`
`RiELTIZ, HIXBIRLEVAIMEAM, BAILIMHPILI—IL (BIA
`
`(SimRRTM2~ 1 20K, HRA LC ILABRIM ILA IL)
`
`RRREME~18OMIT -IVRVEMT Z/RBAVA—IASE
`
`FO TRARUE-REMSIT SONS.
`
`AELTIA, RRRTRM2NABA4DS IX LVEMAIF ONS. m, nit
`
`EACHLT ITSBEIO0O, PEULMIE2ABS OL RICHELCKIES
`
`HE 1ODERCHS.
`
`R*%*, RIKUALI 4 VRECHY, BMI AICMIRLERYALD
`
`4 VICHRS SREMEFONSM, BELSERYU (FY) DTAILEC
`
`HS.
`
`MIZLUFUAL, AUDA, FRUDLESEOPFILAUEEB. AIVYOUALL VY
`
`DPRUDLEOT IA VERSE, PV ELRVDLRISARST VEADULECH
`
`

`

`WO 2011/083850
`
`14
`
`PCT/JP2011/050194
`
`Bo
`
`[0037]
`
`Zé. MB AAE CTE,
`
`(A) BE (a) ARABS HERY
`
`ALIA4 VICHBRTSIOVVZE,L (B) WR (b) RUAALVIPILELY
`
`GeEAtT SVA-ILRVUY REVS SVICHRTSAIOVIEM (A) — (
`
`B) — (A) #ic#§A@ LCE.
`
`(A) — (B) Hina Leis, MKC
`
`NMA DBBAATSHEBSACHSECEMBE LLY.
`
`aomsegvaepb,
`
`(A) FAVE (B) FOYIEORY RLHWMOF
`
`t4 VIR LE (Nn) MARMCHSCEABBELS. . ICR Y RLR
`
`A1. SUPARBPELLY., NnonNCOMACHO¢CBEMILE, HAZED
`
`Gi D SELLY, Nn M2e6BAZASEPOYVIHBARIAMTIVELAYVE
`
`J VUOMMA RIXZSISAU A. FIBER BILET S.
`
`[0038 ]
`
`CHOKDIRBAARE CCK, Widst (1) CHENGSKEIE (A) — (B
`
`) — (A) HOPFOyvyITHESAILMA, Rid—fext (2) CHAN SHI
`
`ZATSAOYIHRSSAMA TONS.
`
`L{b7]
`
`R?
`
`OM
`(OA), —-O-R4*—O-B
`
`(2)
`
`O
`
`beet, RUSVAIWMER MASE FOS TRSERUERA, AIR
`
`REM 2ABZ4O7VIXLUVER, klh17521000FPR, RIEKUALD
`
`4 VRE, MIFV ILA U SB, FILA US, PY VERDALRILARST
`
`VELDAVYAGRL, BILKRRF MEK (3) CRANSBEBERT.
`
`[4b8]
`
`MO
`—(AO),
`
`O
`
`RS
`
`(3)
`
`bait. RISA IMERS MASE FOF VRERUEREA, AIR
`
`

`

`WO 2011/083850
`
`15
`
`PCT/JP2011/050194
`
`ERM 2AEZ4OFVIHEULUVAR, 141 EB1000DBR, RILKUALTD
`
`4 VRE, MLV ILAUSB. FILAUVLRSB, FV E-VULRILART
`
`VEADLERT.
`
`[0039]
`
`S5Ir,
`
`(b) RMAELTHRY L-FILYAIVMCBAT., CMHOMOE FO
`
`AVEAY 2 / BIC BMENERUL—-FILV TP SEVER CS ONSHE
`
`SARE CTIA, Bat—fkxt (4) CHENSILASMMAT SONS.
`
`[469]
`
`R8
`
`OM
`MO
`NH— A’—(OA) , -O—R’—O-(AO),— A’—NH
`
`R?
`
`(4)
`
`O
`
`O
`
`tiexth, RIKYL—-FILV IY SV ERMAT SHOR T-—FILVA—
`
`ILOVA—ILDRA StF FOFVTHRERUYLBER, ALLRRRATM25Z4O
`
`FILE L VE, A’
`
`(tikRRRFRM2GBI4OSILALVA, of, plkene
`
`AIR LT1TbE1 OOD RR, R§, RIAKUAL I 4 VRB, MILPILA
`
`USB. FAURE. PY ELRDARISART VELRULERT.
`
`[0040]
`
`(tat HS #8 ReI
`
`AFASHROREMILAlL, MOBFEAT STHBIL
`
`RMII tT 4.
`
`AVEC Ma) tte LCI, BIAIL, RUAL I 4 Via, RU AFLY
`
`iia, 77LBB, EJ/LBHB. RU S RHEL, RU LDAT ILA, *
`
`YP Rea—ILiBhe, RY A—KRR— bE, MA BERUOLSA Uitia, 2
`
`YRS RUCNbO 2HUEDO BAMA SNS.
`
`[0041]
`
`RUALI 4 VEHBE UTIAL HAIL, TFLY, FOFLY, 1-T9F
`
`Yo VAHAV FY 1-AS RY, 4-AFID-1-ALV FV SEOa-FL
`
`24 VUORIRE SA, Hida -ALI+4VALOKHESA, Mita-ALD
`
`4VEHKESORGAa-ALI4VUNORekeEa-ALI1VEDKE
`
`Bi, RUCKHSOBSWAET SNS. MitDa-ALIa4vVEHEAT
`
`

`

`WO 2011/083850
`
`16
`
`PCT/JP2011/050194
`
`AE a-ALI 7 VUUAOMSAELTIA, BREIL. YLT UB, A
`
`D') DEB, ABD IEA FIL, ABD) IBLF ILSESTECEMTCE
`
`® o
`
`ARUAFLVBBE UTIL, AF LV HORREAAOIR AFLVUMBE
`
`HBA RECGHEALAFLVUMLOREBAARETSNS. BtRMICI,
`
`MUAFELY, FIVOLDRYIL-AFLUVEB (AS). 77UGLDRY
`
`WV-PFAVIY-AF LUE (ABS) SAB SNS.
`
`E/E LUCIA, DIVABAA, HAILDS VOU, RUT VY
`
`PUVBISRMBFONS, RUSS FRB ELTIZ, FT OVSEMBIPS
`
`NS
`
`AU DLAT ILE UTA, RULFLYIFLISAL—bh, RUPFLY
`
`FLISBL—b, RULFLYIFISAL—bFSORBSRRY LATIL RY
`
`FFELYIFYUA— bk, RU LFLYVEDV Ab, RU DFE UEDA
`
`kL RULFLY EDV A— bh, RU PDFLUYE DUR KP UA, OR
`
`YLFLYVHIYAh YXK—b, RUAPADIIEY, RU ABSOI
`
`AKER LAT ILVSREFSNS.
`
`BRU 2A—IDABE LTE, BILAPVILTFE FRIKKUAEOLVOERS
`
`(AMABIF SNS. RYUA—KA—bBABELTIX, EADETI—ILAERA
`
`TYEDHEAW. EADLTI-NAERBMVIATIVEDMAMMNEIT SN
`
`Bo
`
`SAT MERU OLS Ve E LIL, ABUT UL PR bh ERR FUT
`
`—“ILORGMMEBIF Son. Dymtigt UTlk, DyRBARESY—-OZE
`
`FAMBIF SNS,
`
`4.5 AG) BEBOP CHE. RHORUAL OO + UB AEFE LLY.
`
`[0042]
`
`ARO BHILAIDEA Slt, WaVSRHSIIOW LT SE8OR
`
`BSMOMABELCL. STEB2OBSMOMKEYBELLY.
`
`[0043]
`
`AKO BSMILAML, BIRCEtAMRERIETSCEMCESM, A
`
`FRAORWFiS PE SAC. MAIC KYRERAUADBGHAOST ~AVAR
`
`

`

`WO 2011/083850
`
`17
`
`PCT/JP2011/050194
`
`Matta, AFALVAMAA. JHA VDABAAl, MEADEAS
`
`MRA LMA 2A EAA SETHE HEL. KK, RY L—-TIVIAZTIVIG Ss FS
`
`DkLIGEATHEREMILAl, BicMihal, A, BEAL FARIEA, 7
`
`VHRR, SEO ER RIANA SOC thi OD St HS SS GAIN SN SSAA, FE
`
`ARIAT MRA E UL CRMTSCERCES.
`
`[0044]
`
`FIA VAMAAE UTI, BIAIL, DOU ILS FUDAL OD
`
`IVREBA IDL. SUAFIDRBT FUDL, SUAFIRBAUDL,
`
`FIR FUDL. ATS IRR FKUDL. Ae LRT RUD L
`
`, DOV ILRB RK ULE SIS SV SOT IY LRBRUEO : RUA
`
`HVIFLVIDYILI—T IRB bKUDL, RUAEVY LF LU EFI
`
`THT IL RUD L, RUAEV LF LUA ILI—FT LRT bY
`
`Qh. RYUALVLFLYLSDY ILI—F IRB RU LAS —ILV BLY EO
`
`FILS ILL —F IGRBROUE OI | RUAEVIFLYAPFILITAIIT
`
`FILET FU DLO ILEILE —ILIL—F IRB ROUtOE : RY
`
`AHVELFLYVID VBS = FLT IRB bh UDA, RUA LS
`
`LY SUV = KI-FILRBRKU LAY EY, RUARV OF
`
`bYSUAF URS = FI-—TIRRIT bFUDA, RUASYLLFLUAL
`
`4 VERY S FL—TIRBST RUD, RUAEVL LF LUVRS
`
`= FLI—F/LRBT RUD L, ALT UBS SFL TIRBST Fh UD LS
`
`DF ILILT = FRBRUEOIE : Bib VASAT te RD bY
`
`DLO VIVIATIRBROEOE : DIVILAILRUVEBF RKUDL,
`
`SYAFILAZILMRUVBITF KUDAL VU ILSILAILRU BIT bUDLS
`
`OF ILAILAIL7RVBRRUEO ; FTUVILAYVRYVAILDRV BT bFUDL
`
`~ PFYUILAVL EV AIDRV BLU LEAS IVT BV SEOPIEILALV EY
`
`AILARVBRUE OI : FILEILDF ISA LVAILARVBRUEO : +78
`
`LYAILARUVEEORILY ) VERA WSORILY Vi8SaRAILARUEBR
`
`OE OH ; AILARANDRBIDYILAFREUDA, Y-2-LFILNEVIL
`
`AIMRANDBIRKUDL, RUAEVLIFLVAIRAND BID IL2
`
`

`

`WO 2011/083850
`
`18
`
`PCT/JP2011/050194
`
`FRUUDA, PLT VBS FAILDRANDB2F FUDLEOAILARAIN
`
`DRRUOEOR: FT RYVAILRVBTF UDA, TROT RVAILAUE
`
`FRUDL, FRRYVAIDRVYBAUDAL TRITRYAILDRVUBAUTD
`
`LENa-ALIVAIWRVBRUEOIE: A-AIRIDY VBA FIL
`
`LATIL, A-AIRE VAFUBAFIVDILATIL, A-AILRKOIDY VB
`
`(EO) nAFILLATILVDEOD aA -AILARAIBLATIVRUEO : VL
`
`HABER DIL -N-AFILADYVAYUDL, DIATIL-N-AFILA
`
`DYYVIFRKUDA, DIOALIL-NAFILEDYYVAUDA, FIUATIL—
`
`N-AFILADYUEYLAS—-ILF BY. BYAKTILV-N-AFILAD
`I
`WUPRUDA, SURKTIL-N-AFILAEDYUEYULAS—-WSF EY
`
`. VUABRRBRT VD IL-N-AFILEDY UI RUDL, VU IEBT Lv
`
`IL-N-AFILEADYUEYLAUYV—ILG SY SON-FTVILAFIL-B9
`
`VV ROCCO : VURBIBAARR VD IL—- FILS SB VRRAUDA, VU IRA
`
`BBY VIL-TILA SVB bUD AL, V UTAH DV IL—- FILS SUB
`
`YDAYV-IWSFSY, DIUAAI-AFILA SVB RKUDL, ZUAKTIL
`
`—FIVAZVBAUDAL, BUAKTIL-FTIVGA SUB RUDA,L INL
`
`HABER DIL —- TILA SUBST FUDD LSON-SUIIILS SVBRU
`
`EOI: N-FPYVAANAYYLUFRUDA, N-SUAKTIAY YUE
`
`WIRSI—-ILF SY, N-V URIBE DP IL- PU YUP RU DL, NO
`
`VU REBAR DIL- PU DV AUODLSEON-PTVILFU YU RUVEO
`
`DIAS RFAUVBIFRUDL, SURES RFAUBI RUD
`
`A, VU TRESRRERT VILT CFA URI hU DO LEOP VILA PIA UBR
`
`Ut O > PILAILAIL ARREARS | RUASVLFLY SOY ILI—-FILY
`
`VERT FKUDAL RUAEV LF LV eFILI—FILY DBT PUD A, OR
`
`YARVLIFLYVSEUAFILY VRAUDL, RUAZVLIFLYALTIL
`
`I—FILYVRF RKUDA, VRUAEVLFLUALAILI—TILY UE
`
`FRU DLEOPILEILI-TFILY VRRUEOIE : FILEILT J — ILI
`
`FILLY VBRUEOW : RUAFEVLFLYIVDINSS FI-FILY UB
`
`

`

`WO 2011/083850
`
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`
`PCT/JP2011/050194
`
`FRUDLSORMRBST = FI-FILU VURBRUEOH: SOU ILY VRS
`
`RKUDA, SYUAFILY VR RUD, VUTRISRRRU URI RU DL,
`
`SYAFILY VRBAUDA, SUUILDUVRKULAS—-ILF EY, FL
`
`IL') VERY LAS IDV BV SEOTIVSILY VDRRUEOH: SVUOLIG
`
`S/ UBPRT bKUDL, SUOAINA SY CBRE ULaY ILE Ye
`
`DH ABRRERY DLT SY DEPT bFUDL, DUO IS S/R Sb
`
`NOL. N—LSMIERT S/T FU DLSEOP VIL S/R
`
`OEOH : RUALVYIFLYVIDY/LI-FILBRBIT bhUDL, RUA
`
`VIFLYS YVAFILI—T ILERA UIA, RUAEVIFLUINLE F
`
`JVI—7F/LEFRKUDASY—-ILF BY, RY ARV LFLYAT? YJ ILI—
`
`FILER FT FUDAL RU PU RUILSDY ILL— FILES FU DLO
`
`T—TILAILRVUBRUEOIE , VLASR ILIA DF RF SOP VIVE
`
`ADFR RUAEVLIFLYIOY VB? S FL-TILAILRUBT EY
`
`DL. RUALVLF LYS UAF UBT FLT ILAILRVBIT RUD
`
`A, RUA VLIF LUV HARRY S FLAT ILANRVUB FUL
`
`IVF SV SOF = FLI-FILAI RU BRUEO : 7D ILSLE I FIL
`
`TFOIILANDRRUEOMSMAT SNS.
`
`[0045]
`
`AFAVAMBEAIE CTIA, BAIL, DOUILKUAZFILFVERUL
`
`DASA KL, SURFILKEYV AFLP VEAYDLAIAST FL NILE FILE
`
`YAFILPVEZADLIONSA KL RFKFVYUWEKVAFILPVEAVDLIA
`
`BIR, FETIV EY AFILFVEADLIODDTFL RPFIL EU A FILE
`
`VEDADADADHA FY ANZIL EV AFILP VEADAIASTL FL VY
`
`WAP ILL KU A FIL FP VELDVADOST FL FABPILSIL EU A FILE
`
`VEDADAIADL FL ATFFKUILEUVAFILF VEZADLIASKL VY
`
`HAV ILAIL KU AFIL PW VELRDLIOS FL RFILD EU AFILEH VERY
`
`LAF WRBRSOES FILS ILBORS VERDE VADFILYAFIL
`
`PFYEADADOAIA FL VIDYILVAFIP VERADLIASGT FLY
`
`ATF UILGAFILF VEZDLIADT FEOVST IYIGRS VER
`
`

`

`WO 2011/083850
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`
`PCT/JP2011/050194
`
`ith: D/UABY SY PO EILELFILV AF IL VELDALFIL
`
`RE, DPVOFIVF SY LFIVAFILV LFS VELVD LAF IRBRSO
`
`PUVILE SS FINI BORS VERO ASE DIDS FILRU LTS EY
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`LFILF VEDADLIODH FL VAFFK URI LFS EV AFILI VE
`
`=DLIODSL FSOPWHILITF SY FV RORY VEARDAE: DDL
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`AVES VADLIODT FEOS ISI VEY JADA DDUILY
`
`AFILAYVVILG VEADLAIOADT FL ATP UY AFILAYVUILE
`
`ELDLIODDT FEORV PIAL DLE AV VILY AF IL [2-— [2
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`— (p-1,
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`1, 3, S-FRIAFILIFILILIFHY) DhAHY]
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`LFIL} FVYEDAVLIAST FHORV EKA A: PFILEY VAY
`
`LAIADT FENDEY VIOLAS: f SFVV ROLE: N-AATILFIL
`
`FI VIFIVDLAFIVEOY FY AILRUBBE, N-DSUOAILDY SUL
`
`IVLLFILLAT JVIGBIBSOST UILERES SY BT IY ILIAT IVE:
`
`O'JILS = VigBiSoOeR—-MT SVB: VIVUILP 5 UBBESORT
`
`MY 2G: BSMY SUE: AARP S EOP RV OUO LE: DIDI
`
`YOFLYLAY AW VEDADLING FOF FSOPIEIL EUS
`
`WALLY AY AIWF VELD AGS MSIF SNS,
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`[0046]
`
`JIAVAMBEAE UCIAL BAIR, POE (RUFAYIFLY) F
`
`DFILI—TFIL, POE (2-LFIL-A¥FV IL) LT-FIL, POEDDUY
`
`JLI—FIL, POEZSYAFILI-FIL, POERFILI—-TFIL, POER
`
`TF JIVI—-TFIL, POEALHILI—-TFIL, POEL YA YILI-F
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`IL, POENAN=ILI—FIL, RUAHEVLF LY RFILATS JILYI—
`
`FILDEORYAEVYLF LY IP ILVEIVI-FIL; POE: POP (RUA
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`VLIOELY) PFIVI-TFIL, POE+:POPZSUYILI-TFIL, POE
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`-POPtFILI—FIL, POE: POPFTYA—-ILSORUFHVLIFL
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`YVRUAEVLAFOPL YAY A—IWH; POEADVFILIZAIWI—FIL,
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`POE/YIILVIZAILI—-FIL, POEPVOAVITAILI—-FIL, POEF
`
`AFIVLI—FILSORYAEVLFLYS Y—IL—FIW; POERILVE
`
`

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`
`LaI—FIL, POEUVELHMI—TIL; ZOUPOEDS J UFILVA—IL
`
`I—TFIL, POED4 KAT A—-ILSEOLI—TIVR; ESATSI I VUBPO
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`EMU RYUIL, ALT VRPOEFY PU ILDSORUAEVLIFLYL IU &
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`AEGATS J VEBPOEYILE K—JL, FRKOUATFUVBPOEVILE
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`hK—JL, FRKDALTVEBPOEYVYILE KIL, ESSUJUVBPOEYVIL
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`EK—ILSORUALYV OIF LY VYILE K—/DABRAPR LAT IL; RU LFL
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`VIYA-IES II VB, BRU LFLYAYA-IESATT UB,
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`RY DLFLEYAYA-ILESALT VBR, BU LFLY AY A-NYVATS
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`UB. RU LFLYL AYALA LT VBL RU LFLUYFYA—-IWLY
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`4YATF J) VRBSORYLTFIFLY ST J A—IDABRRLAT IL, RULFL
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`VIYA—-ILDS |) VARIALAT IVS OL—TFIVLATIVAZA: ES ATS
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`YUVBAURUIL, BOPbEBES ATP ULVBIU PUL, EYE FOX
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`VATFI IVE RUIL, VATU VBI PR UILSEOT) YU VARA
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`BLATT IL; EAATST VBL RUIL, EAA LT UBT U RU
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`VAT UVBRU TUR UIL, EST YVATI UVR TU RUIL, ESA
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`FF UVVEFKITURUIL,
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`ATFPUVBT RIAU RUIL, EASOY VBALGTYURUIL, ES
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`PARR LATF IL; EYATPUVBFOELLF YAW, BeSibBE/A
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`FF JVBPFOPLYAYA-WSOPFOELY AY A)RLAT IL
`
`

`

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`
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`
`SEY ATTY VBAVALY AY OIL ESA UT VBAKVALYAY
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`BAF ILVIR/S—ILF & FSOMRMRTILAY—ILF SF; POEDDY
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`meae UCI, BIAIL, DIOUILVYAFILABHY, ZURF
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`RY DRE YVLFIL-N-AIMRYVYLFILLFIFL YY PS VAtFhuyd
`
`

`

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`
`LOT 'ULV: RNt*H,CH,CH,COO- (R: FILEIL) CHRENSDT
`
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`Bl DOJ IVAILAREFRRF KUDAL FROTRYVAILMUBRI FUDA,
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`AILARAIIND BY (2 -LFIAEVIL) FRUDL, DOVILVAFILE
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`FOYYLPOFILAILRAS TY, ZEYUAFILVAF ILE FOFVIOEFY
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`EFOSYV IPA EILAILRASD ST VEOAILRASST VE: RN‘H,CH,CH
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`29S Oz (R: FILEIL) CRHENSAILALU BH ; RN*H,CH,CH,OS OF
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`ASV IFIL-N’ -—YVAILRELVIFILD-LFIFEYYTEV2AFRUOL
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`LYUVYEYVIRUDA, N-DSVOTIL-N’ —-AILRALYAFIL—N’
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`-—ERFOXLVIFILPILFLY YF SYVI RUD, N-W VESEY DIL
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`N’
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`-LFLYVPTEVAFRKUDLA, N-FVATIL-N-E FAY LFIL
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`—N’
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`RFFUVIL-N-RUASVIFLY—N’
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`AYLVOIFILTFLYYP SUI bUDL, FOF S/AIRU BH ; 2
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`EBAY) UH; RN*H,CH (CH3) P (OH) O7 (R: VILXIL) CHE
`
`

`

`WO 2011/083850
`
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`
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`
`NOY URE LY FY: DOUILVAFILT ZS BRASIL, VUE
`
`ERPS FFOEILVAFILP S/S BRAS 1 USOT R/S BRAS TU
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`RIBAS RBIP oN, MNOABIO bE CES.
`
`

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`
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`
`[0051]
`
`flo, FA UncH. Wahinwe se EOD RRA fon ILS HOLE E UES
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`RIZEOBS., HonoemrAOWME, MAA, MSH, BRtSORA
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