PTO-1390 (10-20)
`Approved for use through 10/31/2022. OMB 0651-0021
`U.S. Patent and Trademark Office; U.S. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it displays a valid OMB control number.
`
`TRANSMITTAL LETTER TO THE UNITED STATES=|Syqnasipa(115479.000414)
`DESIGNATED/ELECTED OFFICE (DO/EO/US)
`U.S. Application No. (if known, see 37 CFR 1.5)
`CONCERNING A SUBMISSION UNDER35 U.S.C. 371ennee|
`
`International Application No.
`
`International Filing Date
`
`Priority Date Claimed
`
`Title of Invention
`
`First Named Inventor
`
`Applicant herewith submits to the United States Designated/Elected Office (DO/EO/US) the following items and other information.
`1.
`[mi] This is an express request to begin national examination procedures (35 U.S.C. 371(f}). NOTE: The express request under
`35 U.S.C. 371(f) will not be effective unless the requirements under 35 U.S.C. 371(c){1), (2), and (4) for payment of the basic
`national fee, copy of the International Application and English translation thereof (if required), and the oath or declaration of the
`inventor(s) have been received.
`A copy of the International Application (35 U.S.C. 371(c)(2)) is attached hereto (not required if the Intemational Application was
`previously communicated by the International Bureau or wasfiled in the United States Receiving Office (RO/US)).
`An English language translation of the International Application (35 U.S.C. 371(c)(2))
`[mi]
`.
`is attached hereto.
`. [] has been previously submitted under 35 U.S.C. 154(d)(4).
`An oath or declaration of the inventor(s) (35 U.S.C. 371(c)(4))
`[mi]
`.
`is attached.
`. [| waspreviously filed in the international phase under PCT Rule 4.17(iv).
`Items 5 to 8 below concern amendments madein the international phase.
`PCTArticle 19 and 34 amendments
`
`37 CFR 3.73(c) Statement (when there is an Assignee).
`
`5. [| Amendmentsto the claims under PCT Article 19 are attached (not required if communicated by the International Bureau)
`(35 U.S.C. 371(c)(3)).
`6. [| English translation of the PCT Article 19 amendmentis attached (35 U.S.C. 371(c)(3)).
`7. [| English translation of annexes (Article 19 and/or 34 amendmentsonly) of the International Preliminary Examination Report is
`attached (35 U.S.C. 371(c)(5)).
`
`Cancellation of amendments made in the international phase
`
`8a. [| Do not enter the amendment madein the international phase under PCTArticle 19.
`8b. [| Do not enter the amendment madein the international phase under PCTArticle 34.
`NOTE: A proper amendment made in English under Article 19 or 34 will be entered in the U.S. national phase application absent a clear
`instruction from applicant not to enter the amendments).
`
`The following items 9 to 17 concern a document(s) or information included.
`
`AnInformation Disclosure Statement under 37 CFR 1.97 and 1.98.
`
`A preliminary amendment.
`
`An Application Data Sheet under 37 CFR 1.76.
`
`A substitute specification. NOTE: A substitute specification cannot include claims. See 37 CFR 1.125(b).
`
`A powerof attorney and/or change ofaddressletter.
`
`A computer-readable form of the sequencelisting in accordance with PCT Rule 13fer.3 and 37 CFR 1.821-1.825 (not required if
`sequencelisting in text format was indicated on the PCT Request as part of the International Application and the sequencelisting
`was published as part of the international application).
`
`Assignment papers (cover sheet and document(s)). Name of Assignee:
`
`This collection of information is required by 37 CFR 1.414 and 1.491-1.492. The information is required to obtain or retain a benefit by the public, whichis tofile
`(and by the USPTOto process) an application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.11 and 1.14. This collection is estimated to take 15
`minutes to complete, including gathering, preparing, and submitting the completed application form to the USPTO.Timewill vary depending upon the individual
`case. Any comments on the amount of time you require to complete this form and/or suggestions for reducing this burden should be sentto the Chief Information
`Officer, U.S. Patent and Trademark Office, U.S. Department of Commerce, P.O. Box 1450, Alexandria, VA 22313-1450. DO NOT SEND FEES OR COMPLETED
`FORMSTO THIS ADDRESS. SEND TO: Mail Stop PCT, Commissionerfor Patents, P.O. Box 1450, Alexandria, VA 22313-1450.
`
`

`

`PTO-1390 (10-20)
`Approved for use through 10/31/2022. OMB 0651-0021
`U.S. Patent and Trademark Office; U.S. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it displays a valid OMB control number.
`U.S. APPLN. No. (if known - see 37 CFR1.5)
`INTERNATIONAL APPLICATIONNo.
`ATTORNEY DOCKETNo.
`PCT/EP2019/077185
`SYG-451PA(115479.00041 4)
`
`17. [mi] Otheritems orinformation:
`-Written Opinion of the International Search Authority; PCT Request;
`-PCT/IB/308 (2); PCT/IB/301; and
`-Notification Concerning Submission, Obtention or Transmittal of Priority Document.
`
`The following fees have been submitted.
`
`CALCULATIONS
`
`$
`
`$
`
`TOTAL OF 18, 19, and 20 =|$1660.00
`[mi] Additional fee for specification and drawingsfiled in paper over 100 sheets (excluding sequencelisting
`in compliance with 37 CFR 1.821(c) or (e) in an electronic medium or computer program listing in an
`electronic medium) (37 CFR 1.492(j)).
`
`$
`
`540.00
`
`$420
`
`RATE
`
`18. $3201$320.00[mi] Basic national fee (87 CFR 1.492(a)) ...... 00. cee cee teeeetes testes tessststtttitsttessteecceeee
`
`
`19. [mi] Examination fee (37 CFR 1.492(c))
`°
`If the written opinion prepared by ISA/USorthe international preliminary examination report
`$0
`prepared by IPEA/US indicatesall claims satisfy provisions of PCT Article 33(1)-(4)..............
`All other situations 2.0.00... 000.00 cee cee ee tenets settee seeteetseteesesttttseeetestssteeeessese $800
`20. [mi] Search fee (37 CFR 1.492(b))
`If the written opinion prepared by ISA/USorthe international preliminary examination report
`$0
`prepared by IPEA/US indicatesall claims satisfy provisions of PCT Article 33(1)-(4)..............
`Search fee (37 CFR 1.445(a){2)) has been paid on the international application to the USPTO as
`an International Searching Authority ..........0.0.0 0000 coco cece cee eeeceeceeetseeteseeecesteseersesssees $140
`International Search Report prepared by an ISA other than the US and provided to the Office or
`previously communicated to the US by the IB.....0... 0.0.00 cee cece cee ces see testeteteseettereeesess $540
`All other situations ......0.0 0.00.0 cec cee cee cee cee cee cae cae eee cee eeeeee eee cesses sae ecsnaeeteees ens eeeeeeees $700
`
`TOTAL FEES ENCLOSED=|$2080.00
`
`Fee for each additional 50 sheets of paperor fraction thereof ..............0 0c cece cee cee neee teen eee es
`Number of each additional 50 or fraction
`thereof (round up to a whole number)
`
`Extra Sheets
`
`7
`
`/50=
`
`Surcharge for furnishing any of the search fee, examination fee, or the oath or declaration after the date of
`commencementof the national stage (37 CFR 1.492(h))......... 0... cece ccc cee cee cee nee eee ces eeee cee tee seneaeeneee
`NUMBERFILED
`
`15
`
`- 20 =
`
`Processing fee for furnishing the English translation later than 30 months from the earliest claimed priority date
`
`TOTAL OF ABOVE CALCULATIONS =|$ 420.00
`
`C] Applicant certifies micro entity status. See 37 CFR 1.29. Fees above are reduced by%. Po
`
`Applicant must attach form PTO/SB/15Aor B or equivalent.
`
`TOTAL NATIONAL FEE =|$0.00
`
`Fee for recording the enclosed assignment (37 CFR 1.21(h)). The assignment must be accompanied by an
`appropriate cover sheet (37 CFR 3.28, 3.31)... 0. cece ccc cence cee cee eee nee tae cen ene centaeees $50.00 per property
`
`[Page 2 of 3]
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`

`PTO-1390 (10-20)
`Approved for use through 10/31/2022. OMB 0651-0021
`U.S. Patent and Trademark Office; U.S. DEPARTMENT OF COMMERCE
`Under the Paperwork Reduction Act of 1995, no persons are required to respond to a collection of information unless it displays a valid OMB control number.
`: [| A checkin the amountof $
`to cover the above feesis enclosed.
`
`Please charge my Deposit Account No.
`
`in the amountof $
`
`to cover the abovefees.
`
`The Director is hereby authorized to charge additional fees which may be required, or credit any overpayment, to Deposit Account
`No.
`50-2036
`as follows:
`
`[mi] any required fee.
`C] any required fee except for excess claims fees required under 37 CFR 1.492(d) and (e) and multiple dependent claim fee
`required under 37 CFR 1.492(f).
`Fees are to be charged to a credit card. WARNING:
`Information on this form may become public. Credit card information should not
`be included onthis form. Provide credit card information and authorization on PTO-2038. The PTO-2038 should only be mailed or
`faxed to the USPTO. However, when paying the basic national fee, the PTO-2038 may NOTbe faxed to the USPTO.
`
`ADVISORY:If filing by EFS-Web, do NOTattach the PTO-2038 form as a PDF along with your EFS-Web submission. Please be
`advised that this is not recommended and by doing so your credit card information may be displayed via PAIR. To protect your
`information, it is recommendedto pay fees online by using the electronic payment method.
`
`NOTE: Where an appropriate time limit under 37 CFR 1.495 has not been met, a petition to revive (37 CFR 1.137(a)} or (b)} must be
`filed and granted to restore the International Application to pending status.
`
`Statement under 37 CFR 1.55 or 1.78 for AIA (First Inventor to File) Transition Applications
`Cl This application (1) claims priority to or the benefit of an application filed before March 16, 2013, and (2) also contains, or contained at
`any time, a claim to a claimed invention that has an effective filing date on or after March 16, 2013.
`NOTE 1: By providing this statement under 37 CFR 1.55 or 1.78, this application, with a filing date on or after March 16, 2013, will be
`examined underthe first inventorto file provisions of the AIA.
`
`NOTE 2: AU.S. national stage application may not claim priority to the international application of which it is the national phase. The filing
`date of a U.S. national stage application is the international filing date. See 35 U.S.C. 363.
`
`Correspondence Address
`
`[mr] The address associated with Customer Number:
`
`153842
`
`Ol
`
`R [| Correspondence address below
`
`
`
`=|
`=[
`=[[i
`
`=[
`
`April 6, 2021
` sanete |/Toni-Junell Herbert/
`
`einttype)|TOni-Junell Herbert inns [34,348
`
`[Page 3 of 3]
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