To:
`
`Subject:
`
`Greenlight Distribution, L.L.C. (fsaigh@cox.net)
`
`U.S. TRADEMARK APPLICATION NO. 85145526 - MARY JANE'S
`HERBAL INCENSE BLEND - N/A
`
`Sent:
`
`3/9/2011 12:51:42 PM
`
`Sent As:
`
`ECOM109@USPTO.GOV
`
`Attachments: Attachment - 1
`Attachment - 2
`Attachment - 3
`Attachment - 4
`Attachment - 5
`Attachment - 6
`Attachment - 7
`Attachment - 8
`Attachment - 9
`Attachment - 10
`
`UNITED STATES PATENT AND TRADEMARK OFFICE (USPTO)
`OFFICE ACTION (OFFICIAL LETTER) ABOUT APPLICANT’S TRADEMARK APPLICATION
`
`(cid:160) (cid:160)(cid:160)(cid:160) APPLICATION SERIAL NO.(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)
`(cid:160)(cid:160)(cid:160)(cid:160) MARK: MARY JANE'S HERBAL INCENSE
`
`85145526
`
`(cid:160)(cid:160)(cid:160) CORRESPONDENT ADDRESS:
`(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)
`
`11811 N TATUM BLVD STE 3031
`
`(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)
`
`*85145526*
`
`CLICK HERE TO RESPOND TO THIS LETTER:
`http://www.uspto.gov/teas/eTEASpageD.htm
`
`BLEND(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160) (cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)
`(cid:160) (cid:160)
`FRED R. SAIGH(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)
`SAIGH LAW, P.L.L.C.(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)
`(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160) APPLICANT:(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)
`PHOENIX, AZ 85028-1621(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)
`L.L.C.(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160) (cid:160)(cid:160)(cid:160)(cid:160)(cid:160) CORRESPONDENT’S
`(cid:160)(cid:160)(cid:160)
`REFERENCE/DOCKET NO:(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)
`N/A(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160) CORRESPONDENT E-MAIL ADDRESS:(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)(cid:160)
`
`(cid:160) Greenlight Distribution,
`
`fsaigh@cox.net
`
`OFFICE ACTION
`
`STRICT DEADLINE TO RESPOND TO THIS LETTER(cid:160)
`TO AVOID ABANDONMENT OF APPLICANT’S TRADEMARK APPLICATION, THE USPTO MUST
`
`(cid:160)
`

`
`RECEIVE APPLICANT’S COMPLETE RESPONSE TO THIS LETTER WITHIN 6 MONTHS OF THE
`ISSUE/MAILING DATE BELOW.
`
`(cid:160)I
`
`SSUE/MAILING DATE: 3/9/2011
`
`The assigned trademark examining attorney has reviewed the referenced application and has determined
`the following:
`
`NO SIMILAR MARKS
`
`The trademark examining attorney has searched the Office’s database of registered and pending marks
`and has found no conflicting marks that would bar registration under Trademark Act Section 2(d).(cid:160) TMEP
`§704.02; see 15 U.S.C. §1052(d).
`
`Applicant, however, should note the following refusal.
`
`SECTIONS 1 AND 45 REFUSAL – NOT IN LAWFUL USE IN COMMERCE
`
`(cid:160)R
`
`egistration is refused because the applied-for mark, as used in connection with the goods and/or services
`identified in the application, is not in lawful use in commerce.(cid:160) Trademark Act Sections 1 and 45, 15
`U.S.C. §§1051, 1127.
`
`(cid:160)T
`
`o qualify for federal trademark/service mark registration, the use of a mark in commerce must be lawful.(cid:160)
`Gray v. Daffy Dan's Bargaintown, 823 F.2d 522, 526, 3 USPQ2d 1306, 1308 (Fed. Cir. 1987) (stating
`that "[a] valid application cannot be filed at all for registration of a mark without 'lawful use in
`commerce'"); TMEP §907; see In re Stellar Int'l, Inc., 159 USPQ 48, 50-51 (TTAB 1968); CreAgri, Inc.
`v. USANA Health Scis., Inc., 474 F.3d 626, 630, 81 USPQ2d 1592, 1595 (9th Cir. 2007).(cid:160) Thus, any
`goods or services to which the mark is applied must comply with all applicable federal laws.(cid:160) See In re
`Midwest Tennis & Track Co., 29 USPQ2d 1386, 1386 n.2 (TTAB 1993) (noting that "[i]t is settled that
`the Trademark Act's requirement of '"use in commerce," means a "lawful use in commerce," and [that the
`sale or] the shipment of goods in violation of [a] federal statute . . . may not be recognized as the basis for
`establishing trademark rights'" (quoting Clorox Co. v. Armour-Dial, Inc., 214 USPQ 850, 851 (TTAB
`
`1982))); In re Pepcom Indus., Inc., 192 USPQ 400, 401 (TTAB 1976); TMEP §907.(cid:160)(cid:160)
`
`The Controlled Substances Act (CSA) prohibits, among other things, manufacturing, distributing,
`dispensing, or possessing certain controlled substances, including marijuana and marijuana-based
`preparations.(cid:160) 21 U.S.C. §§812, 841(a)(1), 844(a); see also 21 U.S.C. §802(16) (defining "[marijuana]").(cid:160)
`In addition, the CSA makes it unlawful to sell, offer for sale, or use any facility of interstate commerce to
`transport drug paraphernalia, i.e., "any equipment, product, or material of any kind which is primarily
`intended or designed for use in manufacturing, compounding, converting, concealing, producing,
`processing, preparing, injecting, ingesting, inhaling, or otherwise introducing into the human body a
`controlled substance, possession of which is unlawful under [the CSA]."(cid:160) 21 U.S.C. §863.
`
`(cid:160)I
`
`n the present case, the application identifies applicant's goods as follows: “Incense.”
`
`(cid:160)T
`
`he wording contained in the applied-for mark plainly indicates that applicant's identified goods/services
`
`(cid:160)
`(cid:160)(cid:160)
`(cid:160)
`(cid:160)(cid:160)
`(cid:160)(cid:160)
`

`
`include items and/or activities that are prohibited by the CSA, namely, synthetic cannabis.
`
`(cid:160)A
`
`s the attached evidence from Wikipedia shows, the term “herbal incense” refers to illegal synthetic
`cannabis.
`
`(cid:160)B
`
`ecause these goods and/or services are prohibited by the CSA, the applied-for mark, as used in
`connection with such goods and/or services, is not in lawful use in commerce.
`
`(cid:160)A
`
`lthough applicant’s mark has been refused registration, applicant may respond to the refusal by
`submitting evidence and arguments in support of registration.(cid:160) If applicant responds to the refusal to
`register, then applicant must also respond to the requirements set forth below.
`
`COLOR CLAIM AND LOCATION STATEMENT
`
`(cid:160)T
`
`he drawing shows the mark in colors that differ from those specified in the color claim and mark
`description.(cid:160) Specifically, the drawing shows the mark in the colors green, white, yellow, red, black and
`brown; however, the following colors appear in the color claim and mark description:(cid:160) blue and purple.(cid:160)
`The colors in the drawing, color claim, and mark description must all agree.(cid:160) See 37 C.F.R. §§2.37,
`2.52(b)(1); TMEP §§807.07(a) et seq.
`
`(cid:160)A
`
`dditionally, the drawing contains the colors white, black and yellow, but there is not reference to these
`colors in the color claim and mark description.
`
`(cid:160)T
`
`herefore, applicant must submit either a corrected color claim and mark description that agrees with the
`colors depicted in the drawing of the mark, or a substitute color drawing that agrees with the colors
`specified in the color claim and mark description.(cid:160) TMEP §807.07(c).(cid:160) Any additional amendments to the
`applied-for mark will not be accepted if the changes would materially alter the mark.(cid:160) 37 C.F.R. §2.72; see
`TMEP §§807.07(c), 807.14 et seq.
`
`(cid:160)I
`
`f black, white and/or gray appear in the mark and are not being claimed as color, applicant must include
`a statement that the colors black, white, and /or gray represent background, outlining, shading and/or
`transparent areas and are not part of the mark.(cid:160) TMEP §807.07(d)(ii).(cid:160) Generic color names must be used
`
`to describe the colors in the mark, e.g., magenta, yellow, turquoise.(cid:160) TMEP §807.07(a)(i)-(a)(ii).(cid:160)(cid:160)
`
`The following color claim and mark description is suggested:
`
`The colors green, red, brown, yellow, white and black are claimed as a feature of the mark.
`
`(cid:160)T
`
`he mark consists of a profile view of a nude woman's body from head to waist. The woman is
`green and black with red lips and white and black eyes. The woman has long hair that is brown and
`black. The woman has a flower in her hair that is yellow and white and is on top of a green marijuana
`leaf. Behind the woman is a yellow circle with white smoke coming from a white and black
`cigarette held by the woman.(cid:160) The wording “MARY JANE’S” is green and outlined in black above
`the woman.(cid:160) The wording “HERBAL INCENSE BLEND” is red and black on a yellow and black
`scrolled banner below the woman.
`
`DISCLAIMER REQUIRED
`
`(cid:160)(cid:160)
`(cid:160)
`(cid:160)(cid:160)
`

`
`(cid:160)A
`
`pplicant must disclaim the descriptive wording “HERBAL INCENSE BLEND” apart from the mark as
`shown because it merely describes an ingredient, quality, characteristic, function, feature, purpose or use
`of applicant’s goods and/or services. (cid:160) See 15 U.S.C. §§1052(e)(1), 1056(a); In re Steelbuilding.com, 415
`F.3d 1293, 1297, 75 USPQ2d 1420, 1421 (Fed. Cir. 2005); In re Gyulay, 820 F.2d 1216, 1217-18, 3
`
`USPQ2d 1009, 1010 (Fed. Cir. 1987); TMEP §§1213, 1213.03(a).(cid:160)(cid:160)
`
`Specifically, the attached evidence from Wikipedia shows the wording HERBAL INCENSE is commonly
`used in connection with applicant’s type of goods to mean synthetic cannabis. (cid:160) The term BLEND means
`“.” (cid:160) Please see the attached definition from the Merriam-Webster Online Dictionary.(cid:160) Therefore, the
`wording merely describes a blend of synthetic cannabis.
`
`A “disclaimer” is a statement that applicant does not claim exclusive rights to an unregistrable
`component of a mark; it does not affect the appearance of the mark.(cid:160) TMEP §1213.(cid:160) An unregistrable
`component of a mark includes wording and designs that are merely descriptive or generic of the goods
`and/or services, and is wording or an illustration that others would need to use to describe or show their
`goods and services in the marketplace.(cid:160) 15 U.S.C. §1052(e); see TMEP §§1209.03(f), 1213.03 et seq.
`
`(cid:160)T
`
`he following is the accepted standard format for a disclaimer:
`
`No claim is made to the exclusive right to use “HERBAL INCENSE BLEND” apart from the
`mark as shown.
`
`(cid:160)T
`
`MEP §1213.08(a)(i).
`
`(cid:160)F
`
`ailure to comply with a disclaimer requirement can result in a refusal to register the entire mark.(cid:160) TMEP
`§1213.01(b).
`
`SPECIMEN OF USE
`
`(cid:160)T
`
`he specimen is not acceptable because it consists of advertising material for goods.(cid:160) Trademark Act
`Section 45 requires use of the mark “on the goods or their containers or the displays associated therewith
`or on the tags or labels affixed thereto.” (cid:160) 15 U.S.C. §1127; see 37 C.F.R. §2.56(b)(1); TMEP §§904.03,
`904.04(b), (c).
`
`(cid:160)M
`
`aterial that functions merely to tell prospective purchasers about the goods, or to promote the sale of the
`goods, is not acceptable to show trademark use.(cid:160) TMEP §904.04(b).(cid:160) Leaflets, handbills, brochures,
`advertising circulars and other printed advertising material, while normally acceptable for showing use in
`connection with services, generally are not acceptable specimens for showing trademark use in
`connection with goods.(cid:160) See In re MediaShare Corp., 43 USPQ2d 1304, 1307 (TTAB 1997); In re
`
`Schiapparelli Searle, 26 USPQ2d 1520, 1522 (TTAB 1993); TMEP §§904.04(b), (c), 1301.04.(cid:160)(cid:160)
`
`An application based on Section 1(a) must include a specimen showing the applied-for mark in use in
`commerce for each class of goods.(cid:160) Trademark Act Sections 1 and 45, 15 U.S.C. §§1051, 1127; 37 C.F.R.
`
`§§2.34(a)(1)(iv), 2.56(a); TMEP §§904, 904.07(a).(cid:160)(cid:160)
`
`Therefore, applicant must submit the following:
`
`(cid:160)
`(cid:160)
`(cid:160)(cid:160)
`(cid:160)
`

`
`(1)(cid:160) A substitute specimen showing the mark in use in commerce for each class of goods specified
`in the application; and
`
`(2)(cid:160) The following statement, verified with an affidavit or signed declaration under 37 C.F.R.
`§2.20:(cid:160) “ The substitute specimen was in use in commerce at least as early as the filing date
`of the application.” (cid:160) 37 C.F.R. §2.59(a); TMEP §904.05; see 37 C.F.R. §2.193(e)(1).(cid:160) If
`submitting a substitute specimen requires an amendment to the dates of use, applicant must also
`verify the amended dates.(cid:160) 37 C.F.R. §2.71(c); TMEP §904.05.
`
`(cid:160)E
`
`xamples of specimens for goods are tags, labels, instruction manuals, containers, photographs that show
`the mark on the actual goods or packaging, or displays associated with the actual goods at their point of
`
`sale.(cid:160) See TMEP §§904.03 et seq.(cid:160)(cid:160)
`
`To submit a verified substitute specimen online via the Trademark Electronic Application System
`(TEAS), applicant should do the following:(cid:160) (1) answer “yes” to the TEAS response form wizard question
`to “submit a new or substitute specimen;” (2) attach a jpg or pdf file of the substitute specimen; (3) select
`the statement that “The substitute specimen(s) was in use in commerce at least as early as the filing date
`of the application.”; and (4) sign personally or enter personally his/her electronic signature and date after
`the declaration at the end of the TEAS response form. (cid:160) See 37 C.F.R. §§2.59(a), 2.193(a), (c)-(d), (e)(1);
`TMEP §§611.01(c), 804.01(b).(cid:160) Please note that these steps appear on different pages of the TEAS
`
`response form.(cid:160)(cid:160)
`
`If applicant experiences difficulty in submitting the required substitute specimen, supporting statement
`and/or declaration, please e-mail TEAS@uspto.gov for technical assistance regarding the TEAS response
`form.
`
`(cid:160)I
`
`f applicant cannot satisfy the above requirements, applicant may amend the application from a use in
`commerce basis under Section 1(a) to an intent to use basis under Section 1(b), for which no specimen is
`required.(cid:160) See TMEP §806.03(c).(cid:160) However, if applicant amends the basis to Section 1(b), registration will
`not be granted until applicant later amends the application back to use in commerce by filing an
`acceptable allegation of use with a proper specimen.(cid:160) See 15 U.S.C. §1051(c), (d); 37 C.F.R. §§2.76, 2.88;
`
`TMEP §1103.(cid:160)(cid:160)
`
`To amend to Section 1(b), applicant must submit the following statement, verified with an affidavit or
`signed declaration under 37 C.F.R. §2.20:(cid:160) “ Applicant has had a bona fide intention to use the mark
`in commerce on or in connection with the goods listed in the application as of the filing date of the
`application.” (cid:160) 37 C.F.R. §2.34(a)(2); TMEP §806.01(b); see 15 U.S.C. §1051(b); 37 C.F.R. §§2.35(b)(1),
`2.193(e)(1).
`
`(cid:160)P
`
`ending receipt of a proper response, registration is refused because the specimen does not show the
`applied-for mark in use in commerce as a trademark.(cid:160) Trademark Act Sections 1 and 45, 15 U.S.C.
`§§1051, 1127; 37 C.F.R. §§2.34(a)(1)(iv), 2.56(a); TMEP §§904, 904.07(a).
`
`RESPONSE GUIDELINES
`
`(cid:160)F
`
`or this application to proceed toward registration, applicant must explicitly address each refusal and/or
`requirement raised in this Office action.(cid:160) If the action includes a refusal, applicant may provide arguments
`and/or evidence as to why the refusal should be withdrawn and the mark should register.(cid:160) Applicant may
`
`(cid:160)
`(cid:160)(cid:160)
`

`
`also have other options for responding to a refusal and should consider such options carefully.(cid:160) To
`respond to requirements and certain refusal response options, applicant should set forth in writing the
`
`required changes or statements.(cid:160)(cid:160)
`
`If applicant does not respond to this Office action within six months of the issue/mailing date, or responds
`by expressly abandoning the application, the application process will end, the trademark will fail to
`register, and the application fee will not be refunded.(cid:160) See 15 U.S.C. §1062(b); 37 C.F.R. §§2.65(a),
`2.68(a), 2.209(a); TMEP §§405.04, 718.01, 718.02.(cid:160) Where the application has been abandoned for
`failure to respond to an Office action, applicant’s only option would be to file a timely petition to revive
`the application, which, if granted, would allow the application to return to live status.(cid:160) See 37 C.F.R.
`§2.66; TMEP §1714.(cid:160) There is a $100 fee for such petitions.(cid:160) See 37 C.F.R. §§2.6, 2.66(b)(1).
`
`If applicant has questions about the application or this Office action, please telephone the assigned
`trademark examining attorney at the telephone number below.
`
`/Robert J. Struck/
`Robert J. Struck
`Trademark Examining Attorney
`Law Office 109
`Phone - (571) 272-1513
`robert.struck@uspto.gov
`
`(cid:160)(cid:160)
`TEAS PLUS APPLICANTS MUST SUBMIT DOCUMENTS ELECTRONICALLY OR SUBMIT
`FEE:(cid:160) Applicants who filed their application online using the reduced-fee TEAS Plus application must
`continue to submit certain documents online using TEAS, including responses to Office actions.(cid:160) See 37
`C.F.R. §2.23(a)(1).(cid:160) For a complete list of these documents, see TMEP §819.02(b).(cid:160) In addition, such
`applicants must accept correspondence from the Office via e-mail throughout the examination process
`and must maintain a valid e-mail address.(cid:160) 37 C.F.R. §2.23(a)(2); TMEP §§819, 819.02(a).(cid:160) TEAS Plus
`applicants who do not meet these requirements must submit an additional fee of $50 per international
`class of goods and/or services.(cid:160) 37 C.F.R. §2.6(a)(1)(iv); TMEP §819.04.(cid:160) In appropriate situations and
`where all issues can be resolved by amendment, responding by telephone to authorize an examiner’s
`amendment will not incur this additional fee.
`
`(cid:160)T
`
`O RESPOND TO THIS LETTER: (cid:160) Use the Trademark Electronic Application System (TEAS)
`response form at http://teasroa.uspto.gov/roa/.(cid:160) Please wait 48-72 hours from the issue/mailing date before
`using TEAS, to allow for necessary system updates of the application.(cid:160) For technical assistance with
`online forms, e-mail TEAS@uspto.gov.(cid:160) For(cid:160)questions about the Office action itself, please contact the
`assigned examining attorney.(cid:160)(cid:160) Do not respond to this Office action by e-mail;(cid:160)the USPTO does not
`accept e-mailed responses.
`
`(cid:160)W
`
`HO MUST SIGN THE RESPONSE:(cid:160) It must be personally signed by(cid:160)an individual applicant
`or(cid:160)someone with legal authority to bind an applicant (i.e., a corporate officer, a general partner, all joint
`applicants).(cid:160)(cid:160)If an applicant is represented by an attorney, the attorney must sign the response.
`
`(cid:160)(cid:160)
`PERIODICALLY CHECK THE STATUS OF THE APPLICATION: (cid:160) To ensure that applicant does
`
`(cid:160)(cid:160)
`(cid:160)(cid:160)(cid:160)
`

`
`not miss crucial deadlines or official notices, check the status of the application every three to four months
`using Trademark Applications and Registrations Retrieval (TARR) at http://tarr.uspto.gov/. (cid:160) Please keep a
`copy of the complete TARR screen. (cid:160) If TARR shows no change for more than six months, call
`1-800-786-9199. (cid:160) For more information on checking status, see
`http://www.uspto.gov/trademarks/process/status/.
`
`(cid:160)T
`
`O UPDATE CORRESPONDENCE/E-MAIL ADDRESS:(cid:160) Use the TEAS form at
`http://www.uspto.gov/teas/eTEASpageE.htm.
`
`(cid:160)(cid:160)
`

`
`httn:fJen.wikioedia. oru!wikii'Synthetic cannabis
`
`DBJUQIZD11 12:00 25 PM
`
` -r.-..-I
`
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`Article Discussion
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`3.Y”lh,9llC cannabis
`From Wil<ipedia. the free encyclopedia
`
`I Log in I create account
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`Read View source View history
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`
`
`Q I
`
`Synthetic cannabis is a psychoactive herbal and chemical product which. when consumed mimicsthe elfects ofcannabis. It is best
`known by the brand names Kimand Spice,l23 both of which have largely become genericized trademarks used to refer to any synthetic
`cannabis product. (it is also for this reason that synthetic cannabis is ofien referred to as spice pmducl, due to the latter.)
`When synthetic cannabis blends first went on sale in the early 2000s it was thought that they achieved an etfect through a mixture of
`legal herbs. Laboratory analysis in 2008 showed this was not the case and that they in factcontained synthetic cannabinoids which act
`on the body in a similar way to cannabinoids naturally found In cannabis. such as THC. A large and complex variety of synthetic
`cannabinoids, most often cannabicyclohe;(ano|_ JWH-018. JWH-W3. or HU-210, are used in an attempt to avoid the laws which make
`cannabis illegal, making synthetic cannabis a designerdrug. lt has been sold under various brand names, online, in head shops and at
`some gas stations.
`
`
`
`It is olten marketed as "hefbal ir|cerLse". however some brands market their products as "herbal smoking blends". In either case the
`products are usually smoked by users. Although synthetic cannabis does not produce positive results in drugtests for cannabis, it is
`possible to detect its metabolites in human urine. The synthetic cannabinoids contained in synthetic cannabis products have been made illegal in many European countries. On 24
`November 2010. the U.S. Drug Enforcement Agency announced it would make five synthetic cannabinoids Schedule I drugs within a month using emergency powers.[3l Prior to the
`announcement. several US states had already made them illegal under state law. As of March ‘lst, 2011. Spice, K2 and the like are no longer legal alternatives in the United
`States, as an at least one yearlong ban bythe DEA has gone into el"fect_l"l
`Contents{l1ide}
`
`A1159 Dr Spine brand herbal imenge
`
`5‘
`
`' 1 History
`22 Ingredients
`2.1 Synthetic cannabinoid ingredients;
`33 Safety
`failjrugtesting
`25 Legal status
`5.1 Europe
`5 2 South America
`5.3 Asia
`5.4.fl.ustralasia
`5.5 North America
`5.51 Canada
`5.5 2 United States
`;B References
`7Exlerna| links
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`|—lic_-i-nru
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`httn:fJen.wikinedia.orqJ'wikifSynthetic cannabis
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`History
`
`Accordiog to the Psychonaut Web Mapping Research Progect, synthetic carmabis products. sold under the brand name Spice first appeared in Europe in 200-1-.l5] The brand
`"Spice" was reteased in 2004 by the now dormant company The Psyche Deli in London. UK. In 2006 the brand gained popularity. According to the Financial "limes the assets of
`The Psyche Deli rose from £65,613} in 2M6 to £899,000 in 20107, I53 The EMCDIJA repnrted in 20109 that ‘Spice products were identified in 21 of the 30 parlidpaing countries,
`Because 'Spice' was the dominant braid until 2009, the competing brands that started to appear from 2908 on, were also dubbed 'Spice'. Spice car therdore relate to both the
`brand 'Spice', as to all herbal hierids with synthetic carinabinoids added, A survey ofreaders of Mixmag in the UK in 20139, found that one in eight rt-esporiderits had used synthetic
`cannabis, cornpared to 85% who had used carinabism
`
`Ingredients
`Synthetic cainabis is claimed by the niariutacturers to coritain a rnixture of traditionally used medicinal herbs, each of which supposedly produces mild effects with the overall
`blcrid resulting in thc: cannabis like intoxication produced by the product. Herbs listed on the pracloagirig of Spice include Canavalia maritime, Nymphcroa oacruica, Saufcilario none,
`Pedrbirlans densiflora. Leonotis ieonurus. Zorma latifolra. Nelumbo warfare and Leonurus sibrricus. However, when the product was analyzed by laboratories in Gemiariy and
`elsewhere, it was found that many of the characteristic "fingerprint" rnolecules expetzled to be prinserit from the claimed plan! ingredients were not plesent, There were also large
`amounts of synthetic tcscopherol present. This suggested that the actuai ingredients migii not be the same as iiidiat was listed on the packet, and a Gennail government risk
`asceccmixit of the product conducted in Ntwarnbcr 2008 concluded that it w unclear what the adual plant ingriodierits were, where the synthetic tncophuol had come from, and
`inihether the subjective carinabis-like elfects were actuaily produced by any of the claimed piant ingedierits or instead rriigit possibly be caused by a synthetic carinabinoid drug.
`
`Synthetic cannabinoid ingredients
`in January 2009, re-searches at the University of Freiburg in Gamany announced that an acme substance in Spice was 3: undisclosed analogue ofthe synthetic rannabinoid CF’
`47.491431 Later that month, GP 415,97 along mm its dirnethylhexyl, diinethyloctyl and dimethytiionyi hornologues, were added to the German controlled drug si::hedules_l9}l1 91 In
`May the analogue of CF’ 47.49? was named cannabicyclo-hexano|.lm
`In July 2910. it was announced that JWH—U18 is one of the active cornporierits In at ieast three mrsioris oi Spice. |M'!lCi't had been sold ll'1 a number ofcountnes around the world
`since 2002, oflen marketed as incense.llZ}l”lll“ll°3 Another potent synthetic cannabinoid, HU-210, has been repoited to have been found in Spice seized by U.S. Customs and
`Border F'rotecti0n,l1E] An analysis of sample; acquired four weeks after the Gerrriai prohibition of JWH-018 took place found Ihait the cnrripourrd had been replaced wilh JWH-D73,
`[17]
`
`Difiererit ratios or’J‘WH-018 and CP 47,497 and their ariaiogues have been found in different brands of synthetic caririabisllal and rnariufacturers coristaiitiy change the composition
`cifflieir products,“ 91' The arnourit nr.:vvH4i1s in Spice has been found to uayimm 02% to 3°1.F”1
`
`Name
`
`l3_"_l1an11ai:i:n_Iqgii:s| properties ofcannabinoiihfligritified in syriflielii: iainriaiyis, i_iv_itl1 THC for
`'
`Binding affinity for the CB1 receptor
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`__ __
`_
`_
`_
`__
`__
`' Binding alfinily for me CB2
`Ieueplui
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`‘THC
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`:Car1nabicyc|ul1exanUl'
`'
`
`CH,
`
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`= -10_?i1_7 amt”
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`KI = 36.4110 um“
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`= l.lflk!'!0|lWL Reported to be 5tiri'ii=_s' more potent lhai THC, based on giiysioiogical
`.
`..
`I n!:E§§X)f!Sr%lll rat.sl‘2l
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`h1tn:fJen.wikinedia.orqJ'w\kifSynthetic cannabis
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`:HU-210
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`QJWH-018
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`JWH-I173
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`: 234 pM (14:-(Lam times more ;xm:)l231
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`
`
`_N
`_ V,\_«cH:;i<i = 9.ao:5_eo nmml
`
`CH
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`=8_90:E1.80rm-.{213
`
`kg = 2.9-112.65 mnlz“
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`xi=3801-2-1.0nmlan
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`Safety
`No ollicial studies have been conducted on its effects on huma'1s,[24] 'l'l'n:m_[ii its efiects ESE not well do-munented, extremely large doses may cause nega'l.ive eflazts that ate
`Q-erlerallv not noted in marijuana users, §'lJ(‘l'l as incieased agitation and unmitingpsl Professor John W, HLIfl‘man who firs! svntlrlesised man: of the cannabinnids used in svnljrletic
`cannabis is quoted as saying, "Peopte who use it a1e1diots."[2'“"You don't know what it's going to do to yo1.I."[26i A use! who consumed 3 g nfspice Gold every day for seueial
`months showed withdravval symptoms, similat to those associated with witmlrawing from the use of natcotics. Doctois treating the user also noted that his use ofthe product
`showed signs associated with addiction??? One case has been repofled where a usei, who had previously sulfesed from cannabis induced Iecunent psychotic episodes, sufiered
`Ieactivelion of their symptoms alter using Space. Psychiatrists Heating him have suggested that the tack of an anupsychotlc chemical. similar to cannabxdiol found in natuial
`cannanis, may make synthetic cannabis mote likely to induce psychosis than natural CE'1flai)lS.[25]
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`Drug testing
`Space does not cause a positive drug test for cannabis or othet illegal drugs using GC-MS—screening with library search, multi-tasget screening by LC-MSIMS, or immunological
`scieening pl'uCedllfEG.[1Sl[2Tl A study has been conducted into the detection of nletaboiites ufJ\NH-018 in unne, the metabolites we mainly conjugates with glucuromc acid and
`can be reliably detected by GC—MS.I"MS and Lc—Ms.-'Ms_l29l
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`Legal status
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`Europe
`Austria
`The Austrian llnlinistry of Health announced on 18 December 2698 that Spice would be controlled under Paragraph ?'‘8 of their drug law on the wounds that it contains an active
`substance ma: afiects the ruucums ufllle body. and me legaiitv uf.l'u'lll-l-fl18 is under :ewewP"3I3"1l3Z1
`Gelwrany
`JW'l-I-018. CP 4?.-£9? and the (:6. (:3 and C9‘ homologues of CP 47519? aie illegal in Germany since 22 January 2009.119153]
`Finland
`Spice blends we ulaasifiutl as a rrietllcirie in Finland and tlltwelme it is illegid in Didi-.‘I' them inritliuul. ii {.xe5(;ripl.iun. In [.JIac3.1u-.- it is not pu:-itiahle in get a pn-::iL;np1inr:.
`[matron needed]
`Ftanee
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`Jl|'\I'H-018, CP H.497 (and its homologuesj and HU-210 weie all made illegal in France on 24 Februasy 2009.134]
`lrnlslnd
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`hitn:fi'en.wikioedia.orcii'wikii’Synthetic cannabis
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`Ireland
`From June 2t11G,.lV\H-I-018, aiorig wiiiii avarietv or other designer drugs are iiie_dai,[353
`Latvia
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`Jli'\I'H-018, JWl-I-073, CP 47,497 (and its homologues) arid HU-210 are altbarined in Latvia as well as ieonofis .i9Ontl'l't.lS.{363
`Poland
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`JWH-018 and many oniie herbs mentioned on iiie ingredie-n lists orspice and similar preparations were made illegal in May 2009. Tliebill was passed by Poiish seim,[3"[33'
`Polish Senatmi and was signed bytlie P:esideni_[‘*°1
`Romania
`Spice was made iiieeai in Romania on 15 Febniaw 2010?“!
`Russia
`On April 9, 2009, the Chieé Medical Officer ol the Russian Federation issued a resoluuon on reinforcirig control over the sales ofsrnoldng blends. These blends, marketed
`under the trade names AM-H!—-C0. Dream. Spice (Gold. Diarnorid), Zoom. Ex—ses. Yucatan Fire aaid others have been declared to contain Saivia divinarum. Hawaiian Wood
`Rose and Blue Lotus and are prohibited to be sold. These substances have been found to have "psychotropic, narcotic elfects, contain poisonous components and represent
`potential threat for humans". The iesoiouori does not meniJ'oi1 Jli'\i'H-018 or other synthetic cai'inabinoids.[423 On Januav 14-, 2010. the Russian _taoMernrnent issued a statement
`inciuding 23 synthetic carinahinoids found in smoking blends Hawaiian Rose and Blue Lotus on the list of prohibited narcotic arid psychotropic substances. Thus, all of these
`plzmts arid corngiounds are now illegal in the Russia’! FederatiaiI.[43i
`Slovakia
`Spice is legal in the sinuses. The National Arlli-Drug Unit is corisideririg adding it to die iist of oorilrolied suiiaiarices_l““? The latest anti-drug iaw version {ia8i2oii9)vaiid since
`January 2018 still does not mention active compounds ofSpice.[45}
`Sweden
`CP 47,497-C6_ CF’ 47_-197-CT, CP 4749?-CS_ CP 47.41.97-C9_ JWH-018, JWH-073 and HU-213 wave all made illegal in Sweden on 15 fierriba 2009. The bill wa aiccqnted
`en ;io.Iuiy 2{)(l9arnd was putirl efiecton 15 miiembei :-_‘ori9.[‘"51
`Switzerland
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`Spice has been banned in swiiizeiiand,{”T
`United Kingdoln
`Spice was legal in the United Ffingido-no until December 2069, when it was classified as a Class El drug.[4'si
`south America
`Chile
`The cniiean Ministrv of Health on Anni 24, 2009 declared die aaie ofsvnthetic cannabis to be iiiegai.[49]
`Asia
`South Korea
`South Korea officiailv added J‘|M-I-018, CP 47,497 and HU-210 to the coritrolied subslarrce list on July 1, 26-09, effectively maisirig these clierriicais iiiegaiism
`Japan
`Japan hasbenned JWH-H318, CP 4?, 49?, and nemoiogues, arid HU—21fl since Oct. 2ue91=“”'*°” “E959”
`Australasia
`New Zealand
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`Spice is Iilegai in New Zealand. it is classified as a Ctass C controlled dri.i_ta.[513
`North America
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`hltn:f1'en.wil<iiJedia.orq1'wlkifSynthetic cannabis
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`Canada
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`Spice and specific forrns oi .iWH)oo( are not specificaiiy prohibited in Canada, but synthaic cannabis is listed as a schedule ll drug.l52]l53l Health Canada is debating on the
`Sub}-ed_[54][55i
`United States
`See also’ JWH-Dfflitflniten‘ States
`
`Some compounds |llNi.l'Il'li siinthetic cannabis (l-lU-210) are i:urrent!y scheduled in the USA under federai law while others (JWH-073) have been te1'npo1a1'i1y scheduled until final
`determination oftlneir status can be made.l5E] [5-'1l5Bll'l59l The Drug Enforcement Agency (DEA) considers it to be a "drug of concei'ri",l6°}c.i1.ing "...a surge in emergericyaoorn visits
`and calls to poison-control centers. Adverse health elfects associated with its use include seizures, hallucinations, paranoid beliavior, agitaion, anxiety, nausea, vomiting, r