`
`10780 Santa Monica Boulevard
`Suite 105
`Los Angeles, CA 90025
`Ph. 424.320.4850
`Fax. 888.887.2955
`
`EDUCATION
`M.D., MAY 2008
`Keck School of Medicine
`University of Southern California
`
`MBA, MAY 2008
`Marshall School of Business
`University of Southern California
`
`M.A. Linguistics, DEC 1999
`University of California, Los Angeles
`
`B.A. Linguistics, SEPT 1997
`Cum Laude
`University of California, Los Angeles
`
`LICENSURE & CERTIFICATION
`Board certified in Psychiatry by the American Board of Psychiatry and Neurology
`Board certified in Addiction Medicine by the American Board of Preventive Medicine
`Licensed Physician, Medical Board of California
`
`PROFESSIONAL EXPERIENCE
`Founder and Medical Director JUN 2012 – PRESENT
`UCLA Dual Diagnosis Program
`Founder and Medical Director of hospital-based Intensive Outpatient Program specializing in the treatment of
`patients with co-morbid substance use and psychiatric disorders
`
`Founder and Chief Executive Officer JUN 2012 – PRESENT
`Camden Center
`Founder and Chief Executive Officer of a dual diagnosis and primary mental health Partial Hospitalization and
`Intensive Outpatient Program with locations in Los Angeles and San Francisco
`
`Chief Resident Physician JUN 2011 – JUN 2012
`UCLA Anxiety Disorders Program
`
`Resident Physician JUN 2008 – JUN 2012
`Department of Psychiatry
`University of California at Los Angeles
`
`Principal Investigator JUN 2011 – JUN 2012
`The Semel Institute for Neuroscience and Human Behavior at UCLA
`Designed and led research investigating the novel application of compounds for the treatment of
`schizophrenia, mood disorders, and addictive disorders
`
`Principal Investigator JUN 2007 – AUG 2007
`Departments of Anesthesia and Otolaryngology, Keck School of Medicine
`Designed and led research study on opioid-induced changes in voice quality.
`
`Co-Investigator AUG 2006 – AUG 2008
`Department of Cell and Neurobiology, Keck School of Medicine
`Co-author of multiple research articles related to protein kinase C, selenium, and naturally occurring
`polyphenols and their role in cancer prevention, neuritogenesis, and recovery from ischemic stroke.
`
`President AUG 2004 – MAY 2005
`American Medical Association at Keck School of Medicine
`
`President AUG 2004 – MAY 2005
`Students for Training in Substance Use and Health Care at Keck School of Medicine
`
`Laboratory Researcher MAY 2004 – AUG 2004
`Department of Dermatology, Keck School of Medicine
`Contributed to research of gene and protein based therapies for various forms of Epidermolysis Bullosa.
`
`Co-leader AUG 2004 – MAY 2005
`Keck School of Medicine Community Outreach, Substance Abuse Division
`
`President AUG 2003 – MAY 2004
`Keck School of Medicine, Class of 2007
`
`Instructor JAN 2002 – SEP 2002
`Berkeley Review, Los Angeles, CA
`Taught MCAT preparation classes to pre-medical students.
`
`APOTEX EXHIBIT 1049
`Apotex v. Alkermes
`IPR2025-00514
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`Consultant JUN 2000 – JAN 2001
`Tellme, Mountain View, CA
`Linguistic consultant for information services company. Performed phonetic transcription for
`voice recognition technology.
`
`University Instructor WINTER 1999
`UCLA, Teaching with Technology Program
`Taught a course to graduate students and professors in the UCLA Linguistics Department
`on the use of technological teaching aids.
`
`Teaching Assistant SPRING 1998-FALL 1999
`UCLA, Department of Linguistics
`Taught discussion sessions and held office hours for upper and lower division
`courses within the UCLA Linguistics Department.
`
`English Second Language Tutor JAN 1996 – DEC 1997
`UCLA, College Tutorials
`Tutored foreign UCLA students and faculty in English pronunciation, grammar, and writing.
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`Snowboard Instructor NOV 1994 – MARCH 1995
`Schischule Hahnenkamm, Kitzbuhel, Austria
`Snowboard instructor for English and German speakers.
`
`PUBLICATIONS AND PRESENTATIONS
`Schiffman, J.E., (2023) Co-Occurring Mental Health and Substance Use Disorders: Prevalence, Etiology, and
`Treatment. The California Psychologist, Vol. 56, No 1.
`
`Schiffman, J.E., (2021) The Intersection of Psychiatry and 12-step Recovery. San Francisco Marin Medicine, Vol.
`94, No 3.
`
`Schiffman, J.E. (2021). Emerging Treatments. Presentation at The Emergence Conference, Marina Del Rey,
`CA.
`
`Schiffman, J.E. (2019). A Phylogenetic Perspective on the Role of Biogenic Monoamines in the Treatment of
`Trauma Associated Psychiatric Disorders. Presentation at The David Smith Symposium, San Francisco, CA.
`
`Wolitzky-Taylor, K., Schiffman, J.E., (2019) Predictive Associations Among the Repeated Measurements of
`Anxiety, Depression, and Craving in a Dual Diagnosis Program. Journal of Dual Diagnosis, 15(3):140-146.
`
`Schiffman, J.E., (2017). A Trauma-Informed Perspective on Dual Diagnosis. Presentation at the Frontiers in
`Addiction Conference, Torrance CA.
`
`Bystritsky, A., Khalsa, S.S., Cameron, M.E., Schiffman J.E., (2013). Current Diagnosis and Treatment of
`Anxiety Disorders. P.T., 38(1):30-57.
`
`Gopalakrishna, R., Barseghian, B., Sarksian, C., Schiffman, J., Rayudu, D., Gundimeda, U. (2013). Prostate
`cancer progression decreases the cancer prevention by selenium: relation to overexpression of protein kinase C
`and selenoprotein thioredoxin reductase.. Cancer Research, 73. 3677-3677.
`
`Schiffman J.E., Gitlin, M. (2012). Oxycodone for the Treatment of Refractory Bipolar Depression. Journal of
`Clinical Psychiatry, 73(7):992.
`
`Gopalakrishna, R., Arepalli, V., Elhiani, A., Schiffman, J., Gundimeda, U. (2012). Oxidation products of green
`tea polyphenols induce inactivation of PKC isoenzymes and induce cell death via modulation of selenoprotein
`thioredoxin reductase and quinone reductase. Cancer Research, 72. 1609-1609.
`
`Gundimeda, U., McNeill, T. H., Schiffman, J.E., Hinton, D.R., and Gopalakrishna, R., (2012) Green tea
`polyphenols precondition PC12 cells against oxygen-glucose deprivation- induced cell death via laminin
`receptor, generation of sublethal reactive oxygen species, and activation of protein kinase C. Journal of Biological
`Chemistry, 287(41): 34694–34708.
`
`Schiffman, J.E., Davis, M.C., Pierre, J., Saunders, C.S. (2011) Hydroxyzine: Rational Choice for Inpatients with
`Insomnia. Current Psychiatry, 10(3):88.
`
`Gopalakrishna, R., Schiffman, J., Mowatt, K., Gundimeda, Usha. (2011). Curcumin both inactivates and induces
`selenoprotein thioredoxin reductase: dual regulation influences curcumin-induced apoptosis in prostate cancer
`cells. Cancer Research, 71. 3687-3687.
`
`Gundimeda, U., McNeill, T. H., Schiffman, J.E., Hinton, D.R., and Gopalakrishna, R., (2010) Green Tea
`Polyphenols Potentiate the Action of Nerve Growth Factor to Induce Neuritogenesis. Journal of Neuroscience
`Research, 88(16):3644-55.
`
`Gopalakrishna, R., Schiffman, J., Man, J., Lei, L., Wu, A., Gundimeda, U. (2010). Curcumin potentiates the
`cancer-preventive actions of selenium by inactivating selenoprotein thioredoxin reductase in prostate cancer
`cells. Cancer Research, 70. 1889-1889.
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`Gundimeda, U., Schiffman, J. E., Gottlieb, S. N., Roth B., and Gopalakrishna, R. (2009) Negation of
`cancer-preventive actions of selenium by overexpression of protein kinase C and selenoprotein thioredoxin
`reductase. Carcinogenesis, 30, 1553-1561.
`
`Gopalakrishna, R., Gundimeda, U., Schiffman, JE., and McNeill, T. H. (2008) A direct redox regulation of
`protein kinase C isoenzymes mediates oxidant-induced neuritogenesis in PC12 cells. Journal of Biological
`Chemistry, 283(21):14430-44.
`
`Gundimeda, U., Schiffman, J.E., Chhabra, D., Wong, J., Wu, A., and Gopalakrishna, R. (2008) Locally generated
`methylseleninic acid induces specific inactivation of protein kinase C isoenzymes: relevance to
`selenium-induced apoptosis in prostate cancer cells. Journal of Biological. Chemistry, 283, 34519-34531.
`
`Gopalakrishna, R., Schiffman, J., Kapa, N., Mai, H., Gundimeda, U. (2007) Induction of cell death in prostate
`epithelial cells by enhanced proteolysis of selenium oxidized cell survival protein kinase C isoenzymes. Cancer
`Research, (67) (9 Supplement) 23
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`Gopalakrishna, R., Schiffman, J., Gundimeda, U.. (2006). Selenoproteins act as a safeguard against
`selenium-induced cytotoxicity in prostate cancer cells. Cancer Research, (66) (8 Supplement) 920.
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`Gopalakrishna, R., Schiffman, J., and Gundimeda, U. (2007, August). Comparison of membrane translocation
`pattern induced by diacylglycerol and oxidants in prostate epithelial cells. Poster presented at FASEB Summer
`Research Conference, Indian Wells, CA.
`
`HONORS & AWARDS
`Irwin Lasky Research Award 2008
`Thomas Krulisky Scholarship 2007
`American Dermatological Association’s 2004 Medical Student Fellowship
`University of California Fellowship 1997/1998
`UCLA Department of Linguistics Departmental Honors 1997
`UCLA Dean's Honors List 1995-1997
`
`LANGUAGE SKILLS
`Fluent in Spanish and German
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